Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TSTD1 Gene

Aliases for TSTD1 Gene

  • Thiosulfate Sulfurtransferase (Rhodanese)-Like Domain Containing 1 2 3
  • KAT 3 4
  • Thiosulfate Sulfurtransferase/Rhodanese-Like Domain-Containing Protein 1 3
  • Thiosulfate Sulfurtransferase KAT, Putative 3
  • Putative Thiosulfate Sulfurtransferase KAT 3

External Ids for TSTD1 Gene

Summaries for TSTD1 Gene

GeneCards Summary for TSTD1 Gene

TSTD1 (Thiosulfate Sulfurtransferase (Rhodanese)-Like Domain Containing 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TSTD1 Gene

  • Possible role in tumorigenesis

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSTD1 Gene

Genomics for TSTD1 Gene

Genomic Location for TSTD1 Gene

Start:
161,037,631 bp from pter
End:
161,038,990 bp from pter
Size:
1,360 bases
Orientation:
Minus strand

Genomic View for TSTD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TSTD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSTD1 Gene

No data available for Regulatory Elements for TSTD1 Gene

Proteins for TSTD1 Gene

  • Protein details for TSTD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NFU3-TSTD1_HUMAN
    Recommended name:
    Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1
    Protein Accession:
    Q8NFU3
    Secondary Accessions:
    • Q5SY48
    • Q5SY49
    • Q5SY50
    • Q5SY51
    • Q8NFU2
    • Q9BV22

    Protein attributes for TSTD1 Gene

    Size:
    115 amino acids
    Molecular mass:
    12530 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH01699.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15368.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI15369.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for TSTD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TSTD1 Gene

Proteomics data for TSTD1 Gene at MOPED

Post-translational modifications for TSTD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TSTD1 Gene

No data available for DME Specific Peptides for TSTD1 Gene

Domains for TSTD1 Gene

Protein Domains for TSTD1 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for TSTD1 Gene

Graphical View of Domain Structure for InterPro Entry

Q8NFU3

UniProtKB/Swiss-Prot:

TSTD1_HUMAN
Domain:
  • Contains 1 rhodanese domain.:
    • Q8NFU3
genes like me logo Genes that share domains with TSTD1: view

No data available for Gene Families for TSTD1 Gene

Function for TSTD1 Gene

Molecular function for TSTD1 Gene

UniProtKB/Swiss-Prot Function: Possible role in tumorigenesis

miRNA for TSTD1 Gene

miRTarBase miRNAs that target TSTD1

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TSTD1 Gene

Localization for TSTD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TSTD1 Gene

Cytoplasm, perinuclear region. Note=Localized around the nuclear membranes.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TSTD1 Gene COMPARTMENTS Subcellular localization image for TSTD1 gene
Compartment Confidence
mitochondrion 2
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for TSTD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 12817473
GO:0005739 mitochondrion IEA --
GO:0048471 perinuclear region of cytoplasm IEA --
genes like me logo Genes that share ontologies with TSTD1: view

Pathways for TSTD1 Gene

SuperPathways for TSTD1 Gene

No Data Available

Interacting Proteins for TSTD1 Gene

Gene Ontology (GO) - Biological Process for TSTD1 Gene

None

No data available for Pathways by source for TSTD1 Gene

Compounds for TSTD1 Gene

(4) HMDB Compounds for TSTD1 Gene

Compound Synonyms Cas Number PubMed IDs
Cyanide
  • Carbon nitride ion
57-12-5
Sulfite
  • Sulfite ion
14265-45-3
Thiocyanate
  • Ammonium rhodanate
302-04-5
Thiosulfate
  • Hyposulfite
14383-50-7
genes like me logo Genes that share compounds with TSTD1: view

Transcripts for TSTD1 Gene

mRNA/cDNA for TSTD1 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TSTD1 Gene

Thiosulfate sulfurtransferase (rhodanese)-like domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TSTD1 Gene

No ASD Table

Relevant External Links for TSTD1 Gene

GeneLoc Exon Structure for
TSTD1
ECgene alternative splicing isoforms for
TSTD1

Expression for TSTD1 Gene

mRNA expression in normal human tissues for TSTD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TSTD1 Gene

SOURCE GeneReport for Unigene cluster for TSTD1 Gene Hs.720030

mRNA Expression by UniProt/SwissProt for TSTD1 Gene

Q8NFU3-TSTD1_HUMAN
Tissue specificity: Highly expressed in kidney, liver and skeletal muscle. Lower levels of expression in heart, colon, thymus, spleen, placenta and lung. Weakly expressed in brain, small intestine and peripheral blood leukocytes. Expressed at high levels in the breast carcinoma cell lines MCF-7 and MDA-MB-468 and at a lower level in the breast carcinoma cell line MDA-MB-231, the colon carcinoma call line LoVo and the lung carcinoma cell line A-549. No expression in the cell lines EFO-27 and HeLa, or the normal breast tissue cell lines MCF-10A and H184A1. Detected in invasive ductal carcinoma, but not in the adjacent tissues.
genes like me logo Genes that share expressions with TSTD1: view

No data available for mRNA differential expression in normal tissues for TSTD1 Gene

Orthologs for TSTD1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TSTD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TSTD1 35
  • 99.11 (n)
  • 99.11 (a)
TSTD1 36
  • 91 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TSTD1 35
  • 86.43 (n)
  • 89.38 (a)
TSTD1 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TSTD1 35
  • 85.96 (n)
  • 88.6 (a)
TSTD1 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tstd1 35
  • 80.99 (n)
  • 84.21 (a)
Tstd1 16
Tstd1 36
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TSTD1 36
  • 64 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TSTD1 36
  • 31 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tstd1 35
  • 82.46 (n)
  • 84.21 (a)
chicken
(Gallus gallus)
Aves TSTD1 36
  • 28 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TSTD1 36
  • 32 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LOC563265 35
  • 56.79 (n)
  • 52.78 (a)
TSTD1 36
  • 49 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG12279 36
  • 37 (a)
OneToMany
CG6000 36
  • 26 (a)
OneToMany
Hsp67Bb 36
  • 33 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RDL1 36
  • 22 (a)
OneToMany
RDL2 36
  • 23 (a)
OneToMany
RDL2 38
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
OneToOne
Species with no ortholog for TSTD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TSTD1 Gene

ENSEMBL:
Gene Tree for TSTD1 (if available)
TreeFam:
Gene Tree for TSTD1 (if available)

Paralogs for TSTD1 Gene

Pseudogenes.org Pseudogenes for TSTD1 Gene

genes like me logo Genes that share paralogs with TSTD1: view

No data available for Paralogs for TSTD1 Gene

Variants for TSTD1 Gene

Sequence variations from dbSNP and Humsavar for TSTD1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs4339888 -- 161,037,536(+) CAGAT(C/G)AATGC downstream-variant-500B
rs10908821 -- 161,038,745(+) CTCAC(C/G)TGGCA intron-variant
rs17175568 -- 161,038,638(-) CACTC(C/T)TAGCC reference, synonymous-codon, intron-variant
rs17181967 -- 161,037,533(-) TTCAT(C/T)TGCTT downstream-variant-500B
rs17181988 -- 161,038,634(-) CCTAG(C/T)CTCCG reference, missense, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TSTD1 Gene

Variant ID Type Subtype PubMed ID
nsv3221 CNV Loss 18451855

Relevant External Links for TSTD1 Gene

HapMap Linkage Disequilibrium report
TSTD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TSTD1 Gene

Disorders for TSTD1 Gene

Relevant External Links for TSTD1

Genetic Association Database (GAD)
TSTD1
Human Genome Epidemiology (HuGE) Navigator
TSTD1
genes like me logo Genes that share disorders with TSTD1: view

No data available for UniProtKB/Swiss-Prot for TSTD1 Gene

Publications for TSTD1 Gene

  1. Identification and characterization of KAT, a novel gene preferentially expressed in several human cancer cell lines. (PMID: 12817473) Wenzel K. … Hoehe M.R. (Biol. Chem. 2003) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  5. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PMID: 12665801) Gevaert K. … Vandekerckhove J. (Nat. Biotechnol. 2003) 3 4

Products for TSTD1 Gene

Sources for TSTD1 Gene

Back to Top

Content