Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TSSC4 Gene

protein-coding   GIFtS: 48
GCID: GC11P002421

Tumor Suppressing Subtransferable Candidate 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Tumor Suppressing Subtransferable Candidate 41 2
Tumor-Suppressing STF CDNA 4 Protein2 3
Tumor-Suppressing Subchromosomal Transferable Fragment Candidate Gene 4
Protein2 3
Protein TSSC42

External Ids:    HGNC: 123861   Entrez Gene: 100782   Ensembl: ENSG000001842817   OMIM: 6038525   UniProtKB: Q9Y5U23   

Export aliases for TSSC4 gene to outside databases

Previous GC identifers: GC11P002483 GC11P002624 GC11P002381 GC11P002387 GC11P002378 GC11P002380 GC11P002213


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for TSSC4 Gene:
This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of
11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the
Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and
breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the
pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and
disease that involve this region. (provided by RefSeq, Jul 2008)

GeneCards Summary for TSSC4 Gene:
TSSC4 (tumor suppressing subtransferable candidate 4) is a protein-coding gene. Diseases associated with TSSC4 include adrenocortical carcinoma, and wilms tumor.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000011.10  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TSSC4 gene promoter:
         SREBP-1c   MyoD   STAT5A   GATA-1   YY1   SREBP-1b   E47   Ik-2   SREBP-1a   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TSSC4 promoter sequence
   Search Chromatin IP Primers for TSSC4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSSC4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

TSSC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSSC4 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P002421:  view genomic region     (about GC identifiers)

Start:
2,421,718 bp from pter      End:
2,425,106 bp from pter
Size:
3,389 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TSSC4_HUMAN, Q9Y5U2 (See protein sequence)
Recommended Name: Protein TSSC4  
Size: 329 amino acids; 34326 Da
Secondary accessions: C9JS66 Q86VL2 Q9BRS6
Alternative splicing: 2 isoforms:  Q9Y5U2-1   Q9Y5U2-2   

Explore the universe of human proteins at neXtProt for TSSC4: NX_Q9Y5U2

Explore proteomics data for TSSC4 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TSSC4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005697.2  
    ENSEMBL proteins: 
     ENSP00000370384   ENSP00000331087   ENSP00000370380   ENSP00000396925   ENSP00000403475  
     ENSP00000431430   ENSP00000416937   ENSP00000435013   ENSP00000411224  

    TSSC4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TSSC4
    OriGene Protein Over-expression Lysate for TSSC4
    OriGene MassSpec for TSSC4
    OriGene Custom Protein Services for TSSC4
    GenScript Custom Purified and Recombinant Proteins Services for TSSC4
    Novus Biologicals TSSC4 Proteins
    Novus Biologicals TSSC4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for TSSC4
    Cloud-Clone Corp. Proteins for TSSC4

    TSSC4 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TSSC4
    Novus Biologicals TSSC4 Antibody
    Search for Antibodies for TSSC4 at Abcam
    Cloud-Clone Corp. Antibodies for TSSC4
    Search ThermoFisher Antibodies for TSSC4
    Search LSBio for Antibodies for TSSC4

    TSSC4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TSSC4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TSSC4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TSSC4
    Cloud-Clone Corp. CLIAs for TSSC4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus

    ProtoNet protein and cluster: Q9Y5U2

    UniProtKB/Swiss-Prot: TSSC4_HUMAN, Q9Y5U2
    Similarity: Belongs to the TSSC4 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:
         Genatlas biochemistry entry for TSSC4:
    tumor suppressing subchromosomal transferable fragment (STF4),in a center of the 11p15 imprinted domain but
    escaping genomic imprinting

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TSSC4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TSSC4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TSSC4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TSSC4

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TSSC4 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TSSC4
    SwitchGear 3'UTR luciferase reporter plasmidTSSC4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TSSC4
    Predesigned siRNA for gene silencing in human, mouse, rat TSSC4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TSSC4

    Clone
    Products:
         
    OriGene clones in human, mouse for TSSC4 (see all 8)
    OriGene ORF clones in mouse, rat for TSSC4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TSSC4 (NM_005706)
    Sino Biological Human cDNA Clone for TSSC4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSSC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSSC4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TSSC4
    Browse ESI BIO Cell Lines and PureStem Progenitors for TSSC4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSSC4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    golgi apparatus1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TSSC4
    Interactions:

        Search GeneGlobe Interaction Network for TSSC4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    Selected Interacting proteins for TSSC4 (Q9Y5U22, 3 ENSP000003310874) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TAB1Q157502, 3MINT-8260383 I2D: score=2 
    SPTAN1Q138132, 3, ENSP000003618244MINT-64161 I2D: score=5 STRING: ENSP00000361824
    UBA1P223143, ENSP000003384134I2D: score=3 STRING: ENSP00000338413
    KPNA3O005053I2D: score=1 
    PRPF8ENSP000003043504STRING: ENSP00000304350
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TSSC4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TSSC4 gene: 
    NM_005706.2  

    Unigene Cluster for TSSC4:

    Tumor suppressing subtransferable candidate 4
    Hs.523424  [show with all ESTs]
    Unigene Representative Sequence: BC050616
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380996(uc001lwi.3) ENST00000333256(uc001lwk.3 uc001lwl.3)
    ENST00000380992 ENST00000437110 ENST00000435795 ENST00000485682 ENST00000440813
    ENST00000496468 ENST00000467308 ENST00000451491
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TSSC4 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TSSC4
    SwitchGear 3'UTR luciferase reporter plasmidTSSC4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TSSC4
    Predesigned siRNA for gene silencing in human, mouse, rat TSSC4
    Clone
    Products:
         
    OriGene clones in human, mouse for TSSC4 (see all 8)
    OriGene ORF clones in mouse, rat for TSSC4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TSSC4 (NM_005706)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSSC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSSC4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TSSC4
    OriGene qSTAR qPCR primer pairs in human, mouse for TSSC4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSSC4
      QuantiTect SYBR Green Assays in human, mouse, rat TSSC4
      QuantiFast Probe-based Assays in human, mouse, rat TSSC4

    Additional mRNA sequence: 

    AF125568.1 BC006091.1 BC050616.1 

    4 DOTS entries:

    DT.114625  DT.99939205  DT.65285794  DT.97848265 

    Selected AceView cDNA sequences (see all 247):

    BE794027 CR626346 AA459413 AA368609 BI917267 CD671823 AI867354 BF345486 
    BU145815 BM727539 CA389669 BQ637823 BQ654335 AA576770 BM555343 BC050616 
    AI914605 CR612628 AA745925 NM_005706 BC006091 BX438974 BQ062038 BQ051497 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TSSC4 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e
    SP1:                          -     -                 -                 -     -                                 
    SP2:                          -     -     -     -     -                 -     -                                 
    SP3:                          -                 -     -                                                         
    SP4:                          -                       -                                                         
    SP5:                          -     -     -     -     -                                                         


    ECgene alternative splicing isoforms for TSSC4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TSSC4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAGCAGGAA
    TSSC4 Expression
    About this image

    TSSC4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TSSC4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.523424

    UniProtKB/Swiss-Prot: TSSC4_HUMAN, Q9Y5U2
    Tissue specificity: Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues

        Custom PCR Arrays for TSSC4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TSSC4
    OriGene qSTAR qPCR primer pairs in human, mouse for TSSC4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSSC4
    QuantiTect SYBR Green Assays in human, mouse, rat TSSC4
    QuantiFast Probe-based Assays in human, mouse, rat TSSC4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSSC4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TSSC4 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tssc41 , 5 tumor-suppressing subchromosomal transferable fragment more1, 5 72.47(n)1
    66.45(a)1
      7 (88.11 cM)5
    568441  NM_001115085.11  NP_001108557.11 
     1430692495 
    chicken
    (Gallus gallus)
    Aves TSSC41 tumor suppressing subtransferable candidate 4 55.92(n)
    49.67(a)
      423092  NM_001006470.1  NP_001006470.1 
    lizard
    (Anolis carolinensis)
    Reptilia TSSC46
    tumor suppressing subtransferable candidate 4
    42(a)
    1 ↔ 1
    1(69516448-69517494)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC1471331 uncharacterized protein MGC147133 51.7(n)
    40.82(a)
      780083  NM_001079159.1  NP_001072627.1 
    zebrafish
    (Danio rerio)
    Actinopterygii TSSC46
    tumor suppressing subtransferable candidate 4
    29(a)
    1 ↔ 1
    7(34232233-34234353) ENSDARG00000036144


    ENSEMBL Gene Tree for TSSC4 (if available)
    TreeFam Gene Tree for TSSC4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TSSC4 (see all 148)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs751105971,2
    C,F--2421525(+) CCCAGA/CAGGAG 1 -- us2k11Minor allele frequency- C:0.15WA 118
    rs169282421,2
    C,F,H--2421531(+) AGGAGT/CGACGG 1 -- us2k1 tfbs313Minor allele frequency- C:0.15NA NS EA WA CSA 895
    rs1998379401,2
    --2421817(+) GGCGT-/GGAGGAGT 1 -- us2k10--------
    rs110226321,2
    C--2421824(+) AGGAGG/TAGAGG 1 -- us2k1 ese30--------
    rs1912573461,2
    --2421853(+) GGACTA/GCACGT 1 -- us2k10--------
    rs1834470111,2
    --2421856(+) CTACAA/CGTCCC 1 -- us2k10--------
    rs1859881701,2
    --2421965(+) GAGGGC/TTGAGC 1 -- us2k10--------
    rs1910983271,2
    --2421998(+) CGACCA/GAGATG 1 -- us2k10--------
    rs1170218691,2
    F--2422034(+) GTAGGT/ATTGTG 1 -- us2k11Minor allele frequency- A:0.04NA 120
    rs1835218381,2
    --2422247(+) TGGCAC/GCGAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TSSC4 (2421718 - 2425106 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for TSSC4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509382CNV Insertion20534489
    nsv896812CNV Loss21882294
    nsv469928CNV Loss18288195
    nsv896806CNV Loss21882294
    dgv1000n71CNV Loss21882294
    nsv896811CNV Loss21882294
    nsv896821CNV Loss21882294
    nsv896820CNV Loss21882294
    nsv467645CNV Gain19166990

    Human Gene Mutation Database (HGMD): TSSC4
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TSSC4
    DNA2.0 Custom Variant and Variant Library Synthesis for TSSC4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 603852    OMIM disorders: --

    5 diseases for TSSC4:    About MalaCards
    adrenocortical carcinoma    wilms tumor    rhabdomyosarcoma    beckwith-wiedemann syndrome
    breast cancer

    1 disease from the University of Copenhagen DISEASES database for TSSC4:
    Beckwith-Wiedemann syndrome

    TSSC4 for disorders           About GeneDecksing


    Export disorders for TSSC4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TSSC4 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with TSSC4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting. (PubMed id 10072438)1, 2, 3, 9 Lee M.P....Feinberg A.P. (Hum. Mol. Genet. 1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    7. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    8. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (amp 2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    10. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 10078 HGNC: 12386 AceView: TSSC4 Ensembl:ENSG00000184281 euGenes: HUgn10078
    ECgene: TSSC4 H-InvDB: TSSC4

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TSSC4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TSSC4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TSSC4 gene:
    Search GeneIP for patents involving TSSC4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TSSC4  
     OriGene qPCR primer pairs and template standards for TSSC4   OriGene Protein Over-expression Lysate for TSSC4  
     OriGene MassSpec something-or-other for TSSC4   OriGene clones in human, mouse for TSSC4  
     OriGene qSTAR qPCR primer pairs in human, mouse for TSSC4   OriGene Purified Protein for TSSC4  
     OriGene ORF clones in mouse, rat for TSSC4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TSSC4   OriGene Custom Protein Services for TSSC4  

     
     
     Block miRNA regulation of human, mouse, rat TSSC4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TSSC4
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSSC4 Predesigned siRNA for gene silencing in human, mouse, rat TSSC4
     QuantiFast Probe-based Assays in human, mouse, rat TSSC4 QuantiTect SYBR Green Assays in human, mouse, rat TSSC4
     Custom PCR Arrays for TSSC4 Search Chromatin IP Primers for TSSC4
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSSC4  Search GeneGlobe Interaction Network for TSSC4
     Regulatory tfbs in TSSC4 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TSSC4 GenScript cDNA clones with any tag delivered in your preferred vector for TSSC4
     GenScript Custom Assay Services for TSSC4 GenScript Custom overexpressing Cell Line Services for TSSC4
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TSSC4
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for TSSC4
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TSSC4 antibodies
     TSSC4 proteins
     TSSC4 lysates
     Search for Antibodies for TSSC4 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for TSSC4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for TSSC4
     Proteins for TSSC4
     Antibodies for TSSC4
     ELISAs for TSSC4
     CLIAs for TSSC4



     Browse ESI BIO Cell Lines and PureStem Progenitors for TSSC4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSSC4
     SwitchGear 3'UTR luciferase reporter plasmids for TSSC4
     SwitchGear Promoter luciferase reporter plasmids for TSSC4
     Search ThermoFisher Antibodies for TSSC4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSSC4
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TSSC4
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TSSC4
     Search LSBio for Antibodies for TSSC4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TSSC4 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4