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Aliases for TSR3 Gene

Aliases for TSR3 Gene

  • TSR3, Acp Transferase Ribosome Maturation Factor 2 3
  • TSR3, 20S RRNA Accumulation, Homolog (S. Cerevisiae) 2 5
  • C16orf42 3 4
  • Probable Ribosome Biogenesis Protein C16orf42 3
  • TSR3, 20S RRNA Accumulation, Homolog 3
  • Chromosome 16 Open Reading Frame 42 2
  • UND313L 4

External Ids for TSR3 Gene

Previous HGNC Symbols for TSR3 Gene

  • C16orf42

Previous GeneCards Identifiers for TSR3 Gene

  • GC16M001400
  • GC16M001401
  • GC16M001402
  • GC16M001403

Summaries for TSR3 Gene

GeneCards Summary for TSR3 Gene

TSR3 (TSR3, Acp Transferase Ribosome Maturation Factor) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TSR3 Gene

  • Probable pre-rRNA processing protein involved in ribosome biogenesis.

Gene Wiki entry for TSR3 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSR3 Gene

Genomics for TSR3 Gene

Regulatory Elements for TSR3 Gene

Promoters for TSR3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TSR3 on UCSC Golden Path with GeneCards custom track

Genomic Location for TSR3 Gene

Chromosome:
16
Start:
1,349,240 bp from pter
End:
1,351,911 bp from pter
Size:
2,672 bases
Orientation:
Minus strand

Genomic View for TSR3 Gene

Genes around TSR3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TSR3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TSR3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSR3 Gene

Proteins for TSR3 Gene

  • Protein details for TSR3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UJK0-TSR3_HUMAN
    Recommended name:
    Ribosome biogenesis protein TSR3 homolog
    Protein Accession:
    Q9UJK0
    Secondary Accessions:
    • Q6PJT8

    Protein attributes for TSR3 Gene

    Size:
    312 amino acids
    Molecular mass:
    33596 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TSR3 Gene

Proteomics data for TSR3 Gene at MOPED

Post-translational modifications for TSR3 Gene

  • Ubiquitination at Lys 103, Lys 136, and Lys 192
  • Modification sites at PhosphoSitePlus

Other Protein References for TSR3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TSR3 Gene

Domains & Families for TSR3 Gene

Suggested Antigen Peptide Sequences for TSR3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UJK0

UniProtKB/Swiss-Prot:

TSR3_HUMAN :
  • Belongs to the TSR3 family.
Family:
  • Belongs to the TSR3 family.
genes like me logo Genes that share domains with TSR3: view

No data available for Gene Families for TSR3 Gene

Function for TSR3 Gene

Molecular function for TSR3 Gene

UniProtKB/Swiss-Prot Function:
Probable pre-rRNA processing protein involved in ribosome biogenesis.

Phenotypes for TSR3 Gene

genes like me logo Genes that share phenotypes with TSR3: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TSR3 Gene

Localization for TSR3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TSR3 Gene COMPARTMENTS Subcellular localization image for TSR3 gene
Compartment Confidence
cytosol 2
endoplasmic reticulum 1
mitochondrion 1
nucleus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TSR3 Gene

Pathways & Interactions for TSR3 Gene

SuperPathways for TSR3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TSR3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TSR3 Gene

Drugs & Compounds for TSR3 Gene

No Compound Related Data Available

Transcripts for TSR3 Gene

mRNA/cDNA for TSR3 Gene

Unigene Clusters for TSR3 Gene

TSR3, 20S rRNA accumulation, homolog (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TSR3 Gene

No ASD Table

Relevant External Links for TSR3 Gene

GeneLoc Exon Structure for
TSR3
ECgene alternative splicing isoforms for
TSR3

Expression for TSR3 Gene

mRNA expression in normal human tissues for TSR3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TSR3 Gene

This gene is overexpressed in Adrenal (50.7) and Peripheral blood mononuclear cells (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for TSR3 Gene



SOURCE GeneReport for Unigene cluster for TSR3 Gene Hs.134846

genes like me logo Genes that share expression patterns with TSR3: view

Protein tissue co-expression partners for TSR3 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TSR3 Gene

Orthologs for TSR3 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TSR3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TSR3 35
  • 98.57 (n)
  • 97.86 (a)
TSR3 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C25H16ORF42 36
  • 82 (a)
OneToOne
TSR3 35
  • 84.94 (n)
  • 83.65 (a)
dog
(Canis familiaris)
Mammalia TSR3 35
  • 83.45 (n)
  • 81.47 (a)
TSR3 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tsr3 16
Tsr3 36
  • 74 (a)
OneToOne
Tsr3 35
  • 80.04 (n)
  • 77.67 (a)
oppossum
(Monodelphis domestica)
Mammalia TSR3 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TSR3 36
  • 64 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tsr3 35
  • 81.39 (n)
  • 82.33 (a)
chicken
(Gallus gallus)
Aves C14H16ORF42 36
  • 54 (a)
OneToOne
C14H16ORF42 35
  • 60.83 (n)
  • 61.43 (a)
lizard
(Anolis carolinensis)
Reptilia TSR3 36
  • 59 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tsr3 35
  • 57.95 (n)
  • 60.78 (a)
zebrafish
(Danio rerio)
Actinopterygii tsr3 35
  • 59.58 (n)
  • 60.98 (a)
tsr3 36
  • 56 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG4338 36
  • 46 (a)
OneToOne
CG4338 35
  • 55.34 (n)
  • 50.78 (a)
worm
(Caenorhabditis elegans)
Secernentea F52C12.2 36
  • 39 (a)
OneToOne
F52C12.2 35
  • 51.01 (n)
  • 46.46 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TSR3 36
  • 35 (a)
OneToOne
TSR3 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G10070 35
  • 50.97 (n)
  • 51.16 (a)
rice
(Oryza sativa)
Liliopsida Os03g0195200 35
  • 50.46 (n)
  • 49.07 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 52 (a)
OneToOne
Species with no ortholog for TSR3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TSR3 Gene

ENSEMBL:
Gene Tree for TSR3 (if available)
TreeFam:
Gene Tree for TSR3 (if available)

Paralogs for TSR3 Gene

No data available for Paralogs for TSR3 Gene

Variants for TSR3 Gene

Variation tolerance for TSR3 Gene

Residual Variation Intolerance Score: 37.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.49; 28.96% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TSR3 Gene

HapMap Linkage Disequilibrium report
TSR3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TSR3 Gene

Disorders for TSR3 Gene

Relevant External Links for TSR3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TSR3

No disorders were found for TSR3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TSR3 Gene

Publications for TSR3 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3
  5. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PMID: 11157797) Daniels R.J. … Higgs D.R. (Hum. Mol. Genet. 2001) 3

Products for TSR3 Gene

Sources for TSR3 Gene

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