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Aliases for TSR3 Gene

Aliases for TSR3 Gene

  • TSR3, 20S RRNA Accumulation, Homolog (S. Cerevisiae) 2 3
  • C16orf42 3 4
  • Probable Ribosome Biogenesis Protein C16orf42 3
  • Ribosome Biogenesis Protein TSR3 Homolog 3
  • Chromosome 16 Open Reading Frame 42 2
  • UND313L 4

External Ids for TSR3 Gene

Previous HGNC Symbols for TSR3 Gene

  • C16orf42

Previous GeneCards Identifiers for TSR3 Gene

  • GC16M001400
  • GC16M001401
  • GC16M001402
  • GC16M001403

Summaries for TSR3 Gene

GeneCards Summary for TSR3 Gene

TSR3 (TSR3, 20S RRNA Accumulation, Homolog (S. Cerevisiae)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TSR3 Gene

  • Probable pre-rRNA processing protein involved in ribosome biogenesis.

Gene Wiki entry for TSR3 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSR3 Gene

Genomics for TSR3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TSR3 Gene

1,349,240 bp from pter
1,351,911 bp from pter
2,672 bases
Minus strand

Genomic View for TSR3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TSR3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSR3 Gene

No data available for Regulatory Elements for TSR3 Gene

Proteins for TSR3 Gene

  • Protein details for TSR3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ribosome biogenesis protein TSR3 homolog
    Protein Accession:
    Secondary Accessions:
    • Q6PJT8

    Protein attributes for TSR3 Gene

    312 amino acids
    Molecular mass:
    33596 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TSR3 Gene

Proteomics data for TSR3 Gene at MOPED

Post-translational modifications for TSR3 Gene

  • Ubiquitination at Lys103, Lys136, and Lys192
  • Modification sites at PhosphoSitePlus

Other Protein References for TSR3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TSR3 Gene

Domains for TSR3 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TSR3 family.
  • Belongs to the TSR3 family.
genes like me logo Genes that share domains with TSR3: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TSR3 Gene

Function for TSR3 Gene

Molecular function for TSR3 Gene

UniProtKB/Swiss-Prot Function:
Probable pre-rRNA processing protein involved in ribosome biogenesis.

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TSR3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TSR3 Gene

Localization for TSR3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TSR3 Gene

Pathways for TSR3 Gene

SuperPathways for TSR3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TSR3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006364 rRNA processing --
GO:0030490 maturation of SSU-rRNA IBA --
genes like me logo Genes that share ontologies with TSR3: view

No data available for Pathways by source for TSR3 Gene

Transcripts for TSR3 Gene

mRNA/cDNA for TSR3 Gene

Unigene Clusters for TSR3 Gene

TSR3, 20S rRNA accumulation, homolog (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TSR3

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TSR3 Gene

No ASD Table

Relevant External Links for TSR3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TSR3 Gene

mRNA expression in normal human tissues for TSR3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for TSR3 Gene

This gene is overexpressed in Adrenal (50.7) and Peripheral blood mononuclear cells (7.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TSR3 Gene

SOURCE GeneReport for Unigene cluster for TSR3 Gene Hs.134846

genes like me logo Genes that share expressions with TSR3: view

Expression partners for TSR3 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TSR3 Gene

Orthologs for TSR3 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TSR3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TSR3 35
  • 84.94 (n)
  • 83.65 (a)
C25H16ORF42 36
  • 82 (a)
(Canis familiaris)
Mammalia TSR3 35
  • 83.45 (n)
  • 81.47 (a)
TSR3 36
  • 80 (a)
(Mus musculus)
Mammalia Tsr3 35
  • 80.04 (n)
  • 77.67 (a)
Tsr3 16
Tsr3 36
  • 74 (a)
(Pan troglodytes)
Mammalia TSR3 35
  • 98.57 (n)
  • 97.86 (a)
TSR3 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Tsr3 35
  • 81.39 (n)
  • 82.33 (a)
(Monodelphis domestica)
Mammalia TSR3 36
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia TSR3 36
  • 64 (a)
(Gallus gallus)
Aves C14H16ORF42 35
  • 60.83 (n)
  • 61.43 (a)
C14H16ORF42 36
  • 54 (a)
(Anolis carolinensis)
Reptilia TSR3 36
  • 59 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tsr3 35
  • 57.95 (n)
  • 60.78 (a)
(Danio rerio)
Actinopterygii tsr3 35
  • 59.58 (n)
  • 60.98 (a)
tsr3 36
  • 56 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4338 35
  • 55.34 (n)
  • 50.78 (a)
CG4338 36
  • 46 (a)
(Caenorhabditis elegans)
Secernentea F52C12.2 35
  • 51.01 (n)
  • 46.46 (a)
F52C12.2 36
  • 39 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TSR3 36
  • 35 (a)
TSR3 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G10070 35
  • 50.97 (n)
  • 51.16 (a)
(Oryza sativa)
Liliopsida Os03g0195200 35
  • 50.46 (n)
  • 49.07 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 52 (a)
Species with no ortholog for TSR3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TSR3 Gene

Gene Tree for TSR3 (if available)
Gene Tree for TSR3 (if available)

Paralogs for TSR3 Gene

No data available for Paralogs for TSR3 Gene

Variants for TSR3 Gene

Relevant External Links for TSR3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TSR3 Gene

Disorders for TSR3 Gene

No disorders were found for TSR3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TSR3 Gene

Publications for TSR3 Gene

  1. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PMID: 11157797) Daniels R.J. … Higgs D.R. (Hum. Mol. Genet. 2001) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for TSR3 Gene

Sources for TSR3 Gene

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