TSPYL6 Gene
protein-coding GIFtS: 39
GCID: GC02M054480
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|
TSPY-like 6
| |
Aliases
for TSPYL6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| TSPY-Like 61 2 | | TSPY-Like Protein 62 3 | | Testis-Specific Y-Encoded-Like Protein 62 |
Export aliases for TSPYL6 gene to outside databasesPrevious GC identifers: GC02M054391 GC02M054215 |
Summaries
for TSPYL6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TSPYL6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TSPYL6 gene promoter:
TBP C/EBPbeta p53 AML1a LUN-1 RORalpha1 MEF-2A TFIID aMEF-2 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TSPYL6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSPYL6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p16.2 Ensembl cytogenetic band: 2p16.2 HGNC cytogenetic band: 2p16.3TSPYL6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M054480: view genomic region
(about GC identifiers)
Start:
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54,480,315 bp from pter |
End:
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54,483,409 bp from pter |
Size:
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3,095 bases |
Orientation:
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minus strand |
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Proteins
for TSPYL6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TSYL6_HUMAN, Q8N831 (See
protein sequence)Recommended Name: Testis-specific Y-encoded-like protein 6 Size: 410 amino acids; 45874 Da
Secondary accessions: Q6NUJ3Explore the universe of human proteins at neXtProt for TSPYL6: NX_Q8N831
TSPYL6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001003937.2
ENSEMBL proteins: ENSP00000417919
Human Recombinant Protein Products for TSPYL6:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
TSPYL6 for ontologies About GeneDecksing
TSPYL6 Antibody Products:
Assay Products for TSPYL6: |
Protein
Domains /
Families
for TSPYL6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TSPYL6 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N831ProtoNet protein and cluster: Q8N831 1 Blocks protein family: IPB002164 Nucleosome assembly protein (NAP)
UniProtKB/Swiss-Prot: TSYL6_HUMAN, Q8N831Similarity: Belongs to the nucleosome assembly protein (NAP) family |
Function
for TSPYL6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for TSPYL6:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TSPYL6
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TSPYL6
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TSPYL6 (NM_001003937) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TSPYL6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPYL6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL6 |
|
Pathways & Interactions
for TSPYL6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TSPYL6
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006334 | nucleosome assembly |
IEA | -- |
TSPYL6 for ontologies About GeneDecksing
|
Drugs & Compounds
for TSPYL6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TSPYL6
Search CenterWatch for drugs/clinical trials and news about TSPYL6 / TSYL6
|
Transcripts
for TSPYL6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TSPYL6 gene: NM_001003937.2 Unigene Cluster for TSPYL6: TSPY-like 6 Hs.620508 [show with all ESTs]Unigene Representative Sequence: NM_0010039371 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000317802(uc002rxr.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TSPYL6
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TSPYL6
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TSPYL6 (NM_001003937) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TSPYL6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPYL6 |
Additional cDNA sequence: AK097417.1 AL117628.1 BC068576.1 1 DOTS entry: DT.108646 19 AceView cDNA sequences: AA400475 AA970125 AL042471 AK097417 AA776761 AI138392 AA928151 AA973319 AA725832 AA400448 NM_001003937 AW086060 AL117628 BC068576 AL042470 AL042623 AW469541 BG037165 AW085070
GeneLoc Exon Structure
|
Expression
for TSPYL6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TSPYL6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGTAAATAAA
About this image
See TSPYL6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TSPYL6
SOURCE GeneReport for Unigene cluster: Hs.620508
SABiosciences Custom PCR Arrays for TSPYL6
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TSPYL6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TSPYL6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSPYL6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSPYL6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL6 |
Orthologs
for TSPYL6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TSPYL6 gene from 6/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
35(a) |
1 → many |
2(89265460-89270074) |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc:664306 |
zgc:66430 |
20(a) |
1 → many |
8(26561010-26569017) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Set6 |
Set |
26(a) |
1 → many |
3R(11089257-11090975) |
worm
(Caenorhabditis elegans) |
Secernentea |
spr-26 |
Suppressor of presenilin-2 |
22(a) |
1 → many |
IV(8891457-8892734) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
NRP26NRP16 |
template-activating factor I |
27(a)26(a) |
many ↔ manymany ↔ many |
1(6481113-6483596) 1(28017584-28020049) |
rice
(Oryza sativa) |
Liliopsida |
---- |
SET, putative, expressedNAP domain containing protein, putative, expressed... |
29(a)24(a) |
many ↔ manymany ↔ many |
2(22145563-22150173) 4(22758069-22761770) |
ENSEMBL Gene Tree for TSPYL6 (if available)
TreeFam Gene Tree for TSPYL6 (if available) |
Paralogs
for TSPYL6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TSPYL6 gene
- SET2 TSPYL12 TSPY42 TSPY12 TSPY82 TSPYL22 TSPYL52 TSPYL42
- TSPY102 TSPY22 TSPY32
12 SIMAP similar genes for TSPYL6 using alignment to 1 protein entry: TSYL6_HUMAN:TSPYL TSPYL1 TSPYL4 TSPY26P TSPY1 TSPY3
TSPY8 TSPY10 TSPY2 TSPY4 TSPYL2 TSPYL5
TSPYL6 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for TSPYL6
PGOHUM00000247511
|
Genomic Variants
for TSPYL6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TSPYL6 |
|
Disorders
/ Diseases
for TSPYL6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TSPYL6 for disorders About GeneDecksing
4  diseases for TSPYL6: About MalaCardsacute myeloid leukemia myeloid leukemia leukemia malaria
Export disorders for TSPYL6 gene to outside databases
|
Publications
for TSPYL6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TSPYL6 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TSPYL6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for TSPYL6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TSPYL6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TSPYL6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TSPYL6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TSPYL6 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TSPYL6 gene:
Search GeneIP for patents involving TSPYL6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TSPYL6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TSPYL6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TSPYL6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TSPYL6 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TSPYL6 | | OriGene 3'-UTR Clone for TSPYL6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TSPYL6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TSPYL6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TSPYL6 | | OriGene Custom Protein Services for TSPYL6 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TSPYL6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TSPYL6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSPYL6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TSPYL6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSPYL6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSPYL6 |
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 |  |  |  | |
| | | | Search Tocris compounds for TSPYL6 |
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 | | | TSPYL6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL6 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TSPYL6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPYL6 |
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