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TSPYL5 Gene

protein-coding   GIFtS: 51
GCID: GC08M098354

TSPY-Like 5

  Search for TSPYL5
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TSPY-Like 51 2
TSPY-Like Protein 52 3
KIAA17503 5
Testis-Specific Y-Encoded-Like Protein 52

External Ids:    HGNC: 293671   Entrez Gene: 854532   Ensembl: ENSG000001805437   OMIM: 6147215   UniProtKB: Q86VY43   

Export aliases for TSPYL5 gene to outside databases

Previous GC identifers: GC08M098243 GC08M093492


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TSPYL5 Gene:
TSPYL5 (TSPY-like 5) is a protein-coding gene. An important paralog of this gene is SET.

UniProtKB/Swiss-Prot: TSYL5_HUMAN, Q86VY4
Function: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation
of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes
its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from
interaction with USP7




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NC_018919.2  NT_008046.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the TSPYL5 gene promoter:
         Sox5   MyoD   NF-AT   C/EBPalpha   AREB6   CHOP-10   NF-AT2   POU2F1   POU2F1a   NF-AT1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TSPYL5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSPYL5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.1   Ensembl cytogenetic band:  8q22.1   HGNC cytogenetic band: 8q22.1

TSPYL5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSPYL5 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M098354:  view genomic region     (about GC identifiers)

Start:
98,285,714 bp from pter      End:
98,290,176 bp from pter
Size:
4,463 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TSYL5_HUMAN, Q86VY4 (See protein sequence)
Recommended Name: Testis-specific Y-encoded-like protein 5  
Size: 417 amino acids; 45143 Da
Subunit: Interacts with USP7
Sequence caution: Sequence=BAB21841.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B3KRF0 Q9C0B3

Explore the universe of human proteins at neXtProt for TSPYL5: NX_Q86VY4

Explore proteomics data for TSPYL5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys311
  • Modification sites at PhosphoSitePlus

  • See TSPYL5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_277047.2  
    ENSEMBL proteins: 
     ENSP00000322802  

    TSPYL5 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TSPYL5

     
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    TSPYL5 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for TSPYL5

    TSPYL5 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for TSPYL5
    Cloud-Clone Corp. CLIAs for TSPYL5
    Search eBioscience for ELISAs for TSPYL5 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR002164 NAP_family

    Graphical View of Domain Structure for InterPro Entry Q86VY4

    ProtoNet protein and cluster: Q86VY4

    1 Blocks protein domain: IPB002164 Nucleosome assembly protein (NAP)

    UniProtKB/Swiss-Prot: TSYL5_HUMAN, Q86VY4
    Similarity: Belongs to the nucleosome assembly protein (NAP) family


    Find genes that share domains with TSPYL5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TSYL5_HUMAN, Q86VY4
    Function: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation
    of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes
    its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from
    interaction with USP7

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with TSPYL5           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TSPYL5:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TSPYL5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TSPYL5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TSPYL5
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    miRNA
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    Block miRNA regulation of human, mouse, rat TSPYL5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSPYL5 (see all 35):
    hsa-miR-193a-3p hsa-let-7d hsa-miR-513a-5p hsa-miR-29b-1* hsa-miR-4267 hsa-let-7g hsa-let-7a hsa-miR-193b
    SwitchGear 3'UTR luciferase reporter plasmidTSPYL5 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat TSPYL5

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with TSPYL5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TSPYL5
    Interactions:

        Search GeneGlobe Interaction Network for TSPYL5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for TSPYL5 (Q86VY41, 3 ENSP000003228024) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP7Q930091, 3, ENSP000003435354EBI-3436472,EBI-302474 I2D: score=2 STRING: ENSP00000343535
    UBCENSP000003448184STRING: ENSP00000344818
    ASF1AENSP000002295954STRING: ENSP00000229595
    ASF1BENSP000002633824STRING: ENSP00000263382
    H2AFVENSP000003084054STRING: ENSP00000308405
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    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--
    GO:0008284positive regulation of cell proliferation IMP--
    GO:0031398positive regulation of protein ubiquitination IDA--
    GO:0040008regulation of growth IEA--
    GO:0051897positive regulation of protein kinase B signaling IMP--

    Find genes that share ontologies with TSPYL5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TSPYL5 (TSYL5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TSPYL5 gene: 
    NM_033512.2  

    Unigene Cluster for TSPYL5:

    TSPY-like 5
    Hs.173094  [show with all ESTs]
    Unigene Representative Sequence: NM_033512
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000322128(uc003yhy.3)
    miRNA
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    Block miRNA regulation of human, mouse, rat TSPYL5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSPYL5 (see all 35):
    hsa-miR-193a-3p hsa-let-7d hsa-miR-513a-5p hsa-miR-29b-1* hsa-miR-4267 hsa-let-7g hsa-let-7a hsa-miR-193b
    SwitchGear 3'UTR luciferase reporter plasmidTSPYL5 3' UTR sequence
    Inhib. RNA
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    Primer
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    OriGene qPCR primer pairs and template standards for TSPYL5
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSPYL5
      QuantiTect SYBR Green Assays in human, mouse, rat TSPYL5
      QuantiFast Probe-based Assays in human, mouse, rat TSPYL5

    Additional mRNA sequence: 

    AB051537.1 AK091445.1 AK092272.1 AL080059.2 BC045630.1 

    5 DOTS entries:

    DT.97840214  DT.100026974  DT.86846660  DT.100742854  DT.117251 

    Selected AceView cDNA sequences (see all 105):

    AB051537 AA338873 AA973313 F07174 AI076674 AW512403 CD557452 BQ006066 
    BU178255 BQ004589 AA810584 AA781943 BU860463 BQ130523 CD724009 F03819 
    AA403139 Z45560 AL041711 BM684209 NM_033512 AA747824 Z39657 BQ771895 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TSPYL5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGGAAAAAT
    TSPYL5 Expression
    About this image


    TSPYL5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Fibroblasts
             Detroit 551
     
     Epidermis (Integumentary System)
             Detroit 551
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Endothelium (Cardiovascular System)
             Human umbilical vein endothelial cells (HUVEC)
     
     Gonad
             XY Germ Cells Testis Cord
    TSPYL5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TSPYL5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.173094
        Custom PCR Arrays for TSPYL5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TSPYL5 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tspyl51 , 5 testis-specific protein, Y-encoded-like 51, 5 78.19(n)1
    73.83(a)1
      15 (13.91 cM)5
    2393641  NM_001085421.11  NP_001078890.11 
     336838765 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    33(a)
    1 → many
    2(89264771-89274104)
    zebrafish
    (Danio rerio)
    Actinopterygii TSPY26
    testis specific protein, Y-linked 2
    18(a)
    1 → many
    8(26561010-26569017) ENSDARG00000005015
    fruit fly
    (Drosophila melanogaster)
    Insecta Set6
    Set
    30(a)
    1 → many
    3R(11089257-11090975)
    worm
    (Caenorhabditis elegans)
    Secernentea spr-26
    Protein SPR-2, isoform b (spr-2) mRNA, complete cd...
    22(a)
    1 → many
    IV(8891470-8892747) WBGene00005007


    ENSEMBL Gene Tree for TSPYL5 (if available)
    TreeFam Gene Tree for TSPYL5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TSPYL5 gene
    SET2  TSPY6P2  TSPYL12  TSPYL62  TSPY42  TSPY12  TSPY82  TSPYL22  
    TSPYL42  TSPY102  TSPY22  TSPY32  
    6 SIMAP similar genes for TSPYL5 using alignment to 1 protein entry:     TSYL5_HUMAN:
    SET    TSPYL4    TSPY26P    TSPYL1    TSPYL6    TSPYL

    Find genes that share paralogs with TSPYL5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TSPYL5 (see all 172)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1155985621,2
    C--93491704(+) CACCCA/CCCCTT 1 -- int10--------
    rs1894501721,2
    --93491840(+) CACAAC/TTCAGA 1 -- int10--------
    rs1491612991,2
    C--93491861(+) AATTT-/AAGAAGCA 1 -- int10--------
    rs1817699351,2
    --93491917(+) ATTCTA/CATGGG 1 -- int10--------
    rs2005601251,2
    --93492056(+) CTAGT-/CACA  
            
    CAGGG
    1 -- int10--------
    rs1471077051,2
    C--93492057(+) TAGTC-/ACACA 
            
    AGGGT
    1 -- int10--------
    rs570623301,2
    C--93492058(+) AGTCA-/ACAC  
     A
    /CACAA
    GGGTC
    1 -- int10--------
    rs1861282811,2
    --93492350(+) TTCTTC/TCAAAA 1 -- ut310--------
    rs757796321,2
    C,F--93492373(+) GACCAG/ATACAA 1 -- ut311Minor allele frequency- A:0.03WA 118
    rs1139697561,2
    C,F--93492445(+) TCTGGC/TGAAGG 1 -- ut311Minor allele frequency- T:0.50CSA 2

    HapMap Linkage Disequilibrium report for TSPYL5 (98285714 - 98290176 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TSPYL5: --
    Human Gene Mutation Database (HGMD): TSPYL5
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TSPYL5
    DNA2.0 Custom Variant and Variant Library Synthesis for TSPYL5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614721    OMIM disorders: --


    Find genes that share disorders with TSPYL5           About GenesLikeMe

    Genetic Association Database (GAD): TSPYL5

    Export disorders for TSPYL5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TSPYL5 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with TSPYL5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. TSPYL5 suppresses p53 levels and function by physical interaction with USP7. (PubMed id 21170034)1, 2 Epping M.T....Bernards R. (Nat. Cell Biol. 2011)
    3. TSPYL5 is involved in cell growth and the resistance to radiation in A549 cells via the regulation of p21(WAF1/Cip1) and PTEN/AKT pathway. (PubMed id 20079711)1, 2 Kim E.J.... Kim I.G. (Biochem. Biophys. Res. Commun. 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression. (PubMed id 23518928)1 Liu M....Weinshilboum R.M. (Mol. Endocrinol. 2013)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Genome-wide association study of antipsychotic-induced QTc interval prolongation. (PubMed id 20921969)4 Aberg K....van den Oord E.J. (Pharmacogenomics J. 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 85453 HGNC: 29367 AceView: TSPYL5 Ensembl:ENSG00000180543 euGenes: HUgn85453
    ECgene: TSPYL5 H-InvDB: TSPYL5

    (According to HUGE)
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    HUGE: KIAA1750

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TSPYL5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TSPYL5 gene:
    Search GeneIP for patents involving TSPYL5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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