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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TSPYL4 Gene

protein-coding   GIFtS: 48
GCID: GC06M116571

TSPY-Like 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
TSPY-Like 41 2
TSPY-Like Protein 42 3
dJ486I3.22
Testis-Specific Y-Encoded-Like Protein 42
KIAA07213

External Ids:    HGNC: 215591   Entrez Gene: 232702   Ensembl: ENSG000001871897   UniProtKB: Q9UJ043   

Export aliases for TSPYL4 gene to outside databases

Previous GC identifers: GC06M116616 GC06M116677 GC06M114151


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TSPYL4 Gene: 
TSPYL4 (TSPY-like 4) is a protein-coding gene. Diseases associated with TSPYL4 include acute myeloid leukemia, and myeloid leukemia. An important paralog of this gene is SET.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TSPYL4 gene promoter:
         FOXF2   AML1a   POU3F2   E47   Arnt   AREB6   SRY   LyF-1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTSPYL4 promoter sequence
   Search SABiosciences Chromatin IP Primers for TSPYL4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSPYL4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q22.1   Ensembl cytogenetic band:  6q22.1   HGNC cytogenetic band: 6q22.1

TSPYL4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSPYL4 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M116571:  view genomic region     (about GC identifiers)

Start:
116,571,127 bp from pter      End:
116,575,261 bp from pter
Size:
4,135 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TSYL4_HUMAN, Q9UJ04 (See protein sequence)
Recommended Name: Testis-specific Y-encoded-like protein 4  
Size: 414 amino acids; 45126 Da
Sequence caution: Sequence=BAA34441.1; Type=Erroneous initiation;
Secondary accessions: B4DYQ2 O94828 Q96GW8

Explore the universe of human proteins at neXtProt for TSPYL4: NX_Q9UJ04

Explore proteomics data for TSPYL4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UJ04

  • TSPYL4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TSPYL4 Protein Expression
    REFSEQ proteins: NP_067680.3  
    ENSEMBL proteins: 
     ENSP00000410943  

    Human Recombinant Protein Products for TSPYL4: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TSPYL4
    OriGene Protein Over-expression Lysate for TSPYL4
    OriGene MassSpec for TSPYL4 
    OriGene Custom Protein Services for TSPYL4
    GenScript Custom Purified and Recombinant Proteins Services for TSPYL4
    Novus Biologicals TSPYL4 Protein
    Novus Biologicals TSPYL4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TSPYL4 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    TSPYL4 for ontologies           About GeneDecksing



    TSPYL4 Antibody Products: 
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    ThermoFisher Antibodies for TSPYL4
    LSBio Antibodies in human, mouse, rat for TSPYL4 

    Assay Products for TSPYL4: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for TSPYL4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TSPYL4 
    Cloud-Clone Corp. CLIAs for TSPYL4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR002164 NAP_family

    Graphical View of Domain Structure for InterPro Entry Q9UJ04

    ProtoNet protein and cluster: Q9UJ04

    1 Blocks protein domain: IPB002164 Nucleosome assembly protein (NAP)

    UniProtKB/Swiss-Prot: TSYL4_HUMAN, Q9UJ04
    Similarity: Belongs to the nucleosome assembly protein (NAP) family


    TSPYL4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TSPYL4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TSPYL4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TSPYL4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TSPYL4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TSPYL4
    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate TSPYL4 (see all 41):
    hsa-miR-607 hsa-miR-4328 hsa-miR-548k hsa-miR-485-3p hsa-miR-1258 hsa-miR-30d hsa-miR-507 hsa-miR-371-5p
    SwitchGear 3'UTR luciferase reporter plasmidTSPYL4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TSPYL4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TSPYL4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TSPYL4
    Sirion Biotech Customized adenovirus for overexpression of TSPYL4

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TSPYL4 (see all 7)
    OriGene ORF clones in mouse, rat for TSPYL4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TSPYL4 (NM_021648)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSPYL4
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TSPYL4
    Sirion Biotech Customized lentivirus for stable overexpression of TSPYL4 
                         Customized lentivirus expression plasmids for stable overexpression of TSPYL4 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TSPYL4
    Search LifeMap BioReagents cell lines for TSPYL4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TSPYL4

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/67 Interacting proteins for TSPYL4 (Q9UJ042, 3 ENSP000004109434) via UniProtKB, MINT, STRING, and/or I2D (see all 67)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158343, ENSP000003116954I2D: score=4 STRING: ENSP00000311695
    NINLQ9Y2I63, ENSP000002788864I2D: score=4 STRING: ENSP00000278886
    CELSR3Q9NYQ73, ENSP000001640244I2D: score=3 STRING: ENSP00000164024
    FOSP011003I2D: score=1 
    BAG2O958162MINT-8415355
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--

    TSPYL4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TSPYL4 (TSYL4)

    Search CenterWatch for drugs/clinical trials and news about TSPYL4 / TSYL4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TSPYL4 gene: 
    NM_021648.4  

    Unigene Cluster for TSPYL4:

    TSPY-like 4
    Hs.284141  [show with all ESTs]
    Unigene Representative Sequence: NM_021648
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000420283(uc003pwn.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TSPYL4
    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate TSPYL4 (see all 41):
    hsa-miR-607 hsa-miR-4328 hsa-miR-548k hsa-miR-485-3p hsa-miR-1258 hsa-miR-30d hsa-miR-507 hsa-miR-371-5p
    SwitchGear 3'UTR luciferase reporter plasmidTSPYL4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TSPYL4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TSPYL4
    Clone
    Products:
         
    OriGene clones in human, mouse for TSPYL4 (see all 7)
    OriGene ORF clones in mouse, rat for TSPYL4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TSPYL4 (NM_021648)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSPYL4
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TSPYL4
    Sirion Biotech Customized lentivirus for stable overexpression of TSPYL4 
                         Customized lentivirus expression plasmids for stable overexpression of TSPYL4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TSPYL4
    OriGene qSTAR qPCR primer pairs in human, mouse for TSPYL4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TSPYL4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSPYL4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSPYL4

    Additional mRNA sequence: 

    AB018264.1 AJ420569.1 AK091559.1 AK302542.1 AL049347.1 AL137639.1 BC009116.1 BC040453.1 

    4 DOTS entries:

    DT.455106  DT.121344653  DT.447340  DT.95213659 

    24/134 AceView cDNA sequences (see all 134):

    BM991040 AW964188 AI184732 AI697750 BU177679 AI698113 AA287683 AA468256 
    BQ778159 CR603581 BC040453 BF437966 BQ771567 AW419157 BU787664 F01388 
    AI421564 BM720525 BC009116 AW662150 AI874014 C01943 AA452859 AI457849 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TSPYL4 expression in normal human tissues (normalized intensities)      TSPYL4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCTTGAAGG
    TSPYL4 Expression
    About this image


    TSPYL4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             ganglion/cranial/facial VII   
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Eye (Sensory Organs)
             Retina

    See TSPYL4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TSPYL4

    SOURCE GeneReport for Unigene cluster: Hs.284141
        SABiosciences Custom PCR Arrays for TSPYL4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TSPYL4
    OriGene qSTAR qPCR primer pairs in human, mouse for TSPYL4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TSPYL4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSPYL4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSPYL4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TSPYL4 gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tspyl41 , 5 TSPY-like 41, 5 81.48(n)1
    79.51(a)1
      10 (18.85 cM)5
    724801  NM_030203.21  NP_084479.11 
     342974425 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    29(a)
    1 → many
    2(89264771-89274104)
    zebrafish
    (Danio rerio)
    Actinopterygii TSPYL16
    TSPY-like 1
    19(a)
    1 → many
    8(26561010-26569017)
    fruit fly
    (Drosophila melanogaster)
    Insecta Set6
    Set
    28(a)
    1 → many
    3R(11089257-11090975)
    worm
    (Caenorhabditis elegans)
    Secernentea spr-26
    Suppressor of presenilin-2
    21(a)
    1 → many
    IV(8891470-8892747)


    ENSEMBL Gene Tree for TSPYL4 (if available)
    TreeFam Gene Tree for TSPYL4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TSPYL4 gene
    SET2  TSPY6P2  TSPYL12  TSPYL62  TSPY42  TSPY12  TSPY82  TSPYL22  
    TSPYL52  TSPY102  TSPY22  TSPY32  
    15 SIMAP similar genes for TSPYL4 using alignment to 2 protein entries:     TSYL4_HUMAN (see all proteins):
    DKFZp434M235    LOC728395    TSPYL6    SET    TSPY26P    TSPYL
    TSPYL1    TSPY8    TSPY10    TSPY2    TSPY3    TSPY4
    TSPY6P    TSPY1    TSPYL5

    TSPYL4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/52 SNPs in TSPYL4 are shown (see all 52)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0502284
    ----see VAR_0502282 R L mis40--------
    rs1418642301,2
    --116570636(+) ATTACC/TGGTAA 1 -- int10--------
    rs1836765721,2
    --116570656(+) TGATAC/TCTGAT 1 -- int10--------
    rs1476562751,2
    C--116570658(+) TACCT-/GAGATAT 1 -- int10--------
    rs1462332131,2
    --116570688(+) TATTTC/TATATT 1 -- int10--------
    rs1890177061,2
    --116570748(+) AAGTAA/GCACTG 1 -- int10--------
    rs1931611651,2
    --116570757(+) TGACAA/GAATAC 1 -- int10--------
    rs1843893781,2
    --116570791(+) TCTATA/CTTAAG 1 -- int10--------
    rs1869341011,2
    C--116570810(+) ATCTCA/GGAAGG 1 -- int10--------
    rs12048311,2
    C,F,A,H--116570824(-) TATTAT/ATAACT 1 -- int19Minor allele frequency- A:0.28NS EA NA CSA WA 774

    HapMap Linkage Disequilibrium report for TSPYL4 (116571127 - 116575261 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TSPYL4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv523972CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TSPYL4
    DNA2.0 Custom Variant and Variant Library Synthesis for TSPYL4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for TSPYL4:    About MalaCards
    acute myeloid leukemia    myeloid leukemia    leukemia


    TSPYL4 for disorders           About GeneDecksing


    Export disorders for TSPYL4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TSPYL4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TSPYL4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    4. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2 Nagase T.... Ohara O. (1998)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    8. Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. (PubMed id 12421765)1 Nakayama M....Ohara O. (2002)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23270 HGNC: 21559 AceView: TSPYL4 Ensembl:ENSG00000187189 euGenes: HUgn23270
    ECgene: TSPYL4 H-InvDB: TSPYL4

    (According to HUGE)
    About This Section
    HUGE: KIAA0721

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TSPYL4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TSPYL4 gene:
    Search GeneIP for patents involving TSPYL4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TSPYL4
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     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TSPYL4
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     GenScript Custom Purified and Recombinant Proteins Services for TSPYL4 GenScript cDNA clones with any tag delivered in your preferred vector for TSPYL4
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     Regulatory tfbs in TSPYL4 promoter
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     Proteins for TSPYL4
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     SwitchGear 3'UTR luciferase reporter plasmids for TSPYL4
     SwitchGear Promoter luciferase reporter plasmids for TSPYL4
     ThermoFisher Antibodies for TSPYL4
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TSPYL4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TSPYL4
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TSPYL4
    Customized:
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     LSBio Antibodies in human, mouse, rat for TSPYL4
    Customized transgenic rodents for:
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


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