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TSPYL1 Gene

protein-coding   GIFtS: 52
GCID: GC06M116601

TSPY-Like 1

(Previous name: TSPY-like)
(Previous symbol: TSPYL)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TSPY-Like 11 2     Testis-Specific Y-Encoded-Like Protein 12
TSPYL1 2 3 5     Testis-Specific-Like Protein, Y Encoded2
TSPY-Like Protein 12 3     SIDDT5
TSPY-like1     

External Ids:    HGNC: 123821   Entrez Gene: 72592   Ensembl: ENSG000001892417   OMIM: 6047145   UniProtKB: Q9H0U93   

Export aliases for TSPYL1 gene to outside databases

Previous GC identifers: GC06M116643 GC06M116704 GC06M114176 GC06M116599


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TSPYL1 Gene:
The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the
Y-chromosome. This gene is intronless. Defects in this gene are a cause of sudden infant death with dysgenesis of
the testes syndrome (SIDDT). (provided by RefSeq, Dec 2009)

GeneCards Summary for TSPYL1 Gene:
TSPYL1 (TSPY-like 1) is a protein-coding gene. Diseases associated with TSPYL1 include sudden infant death with dysgenesis of the testes syndrome, and sudden infant death syndrome. An important paralog of this gene is SET.

Gene Wiki entry for TSPYL1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the TSPYL1 gene promoter:
         HOXA9B   HOXA9   HOXA3   AML1a   STAT5A   SRY   POU2F1   POU2F1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTSPYL1 promoter sequence
   Search Chromatin IP Primers for TSPYL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSPYL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q22.1   Ensembl cytogenetic band:  6q22.1   HGNC cytogenetic band: 6q22.1

TSPYL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSPYL1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M116601:  view genomic region     (about GC identifiers)

Start:
116,596,022 bp from pter      End:
116,601,280 bp from pter
Size:
5,259 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TSYL1_HUMAN, Q9H0U9 (See protein sequence)
Recommended Name: Testis-specific Y-encoded-like protein 1  
Size: 437 amino acids; 49192 Da
Secondary accessions: O75885 Q5TFE6

Explore the universe of human proteins at neXtProt for TSPYL1: NX_Q9H0U9

Explore proteomics data for TSPYL1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys256
  • Modification sites at PhosphoSitePlus

  • See TSPYL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003300.1  
    ENSEMBL proteins: 
     ENSP00000357597  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR002164 NAP_family

    Graphical View of Domain Structure for InterPro Entry Q9H0U9

    ProtoNet protein and cluster: Q9H0U9

    1 Blocks protein domain: IPB002164 Nucleosome assembly protein (NAP)

    UniProtKB/Swiss-Prot: TSYL1_HUMAN, Q9H0U9
    Similarity: Belongs to the nucleosome assembly protein (NAP) family


    TSPYL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    TSPYL1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TSPYL1:
     Increased number of cells in m 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TSPYL1
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    miRNA
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    miRTarBase miRNAs that target TSPYL1:
    hsa-mir-197-3p (MIRT004190), hsa-mir-1260b (MIRT052748), hsa-mir-92b-3p (MIRT040692), hsa-mir-877-3p (MIRT036870), hsa-mir-320c (MIRT036165)

    Block miRNA regulation of human, mouse, rat TSPYL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSPYL1 (see all 16):
    hsa-miR-579 hsa-miR-148b hsa-miR-3133 hsa-miR-548l hsa-miR-570 hsa-miR-186 hsa-miR-3148 hsa-miR-148a
    SwitchGear 3'UTR luciferase reporter plasmidTSPYL1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TSPYL1

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPYL1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TSYL1_HUMAN, Q9H0U9: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm ----

    TSPYL1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TSPYL1 About    
    See pathways by source

    SuperPathContained pathways About
    1SIDS Susceptibility Pathways
    SIDS Susceptibility Pathways


    1 BioSystems Pathway for TSPYL1
        SIDS Susceptibility Pathways


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TSPYL1
    Interactions:

        Search GeneGlobe Interaction Network for TSPYL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for TSPYL1 (Q9H0U93 ENSP000003575974) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SLX4Q8IY923, ENSP000002940084I2D: score=2 STRING: ENSP00000294008
    CTNNA1P352213I2D: score=2 
    HAP1P542573I2D: score=2 
    JUNP054123I2D: score=2 
    DVL3Q929973I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--
    GO:0008150biological_process ND--

    TSPYL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TSPYL1 (TSYL1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TSPYL1 gene: 
    NM_003309.3  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000368608(uc003pwp.4)
    miRNA
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    Block miRNA regulation of human, mouse, rat TSPYL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSPYL1 (see all 16):
    hsa-miR-579 hsa-miR-148b hsa-miR-3133 hsa-miR-548l hsa-miR-570 hsa-miR-186 hsa-miR-3148 hsa-miR-148a
    SwitchGear 3'UTR luciferase reporter plasmidTSPYL1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TSPYL1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPYL1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TSPYL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSPYL1
      QuantiTect SYBR Green Assays in human, mouse, rat TSPYL1
      QuantiFast Probe-based Assays in human, mouse, rat TSPYL1

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TSPYL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGTTCTGCT
    TSPYL1 Expression
    About this image

    TSPYL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TSPYL1 Protein Expression

    UniProtKB/Swiss-Prot: TSYL1_HUMAN, Q9H0U9
    Tissue specificity: Expressed in testis, ovary, liver, spleen, brain, kidney, prostate, lung, liver, and heart

        Custom PCR Arrays for TSPYL1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPYL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TSPYL1 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tspyl11 , 5 testis-specific protein, Y-encoded-like 11, 5 78.18(n)1
    75.45(a)1
      10 (18.85 cM)5
    221101  NM_009433.31  NP_033459.11 
     342821905 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    34(a)
    1 → many
    2(89264771-89274104)
    zebrafish
    (Danio rerio)
    Actinopterygii TSPY26
    testis specific protein, Y-linked 2
    21(a)
    1 → many
    8(26561010-26569017) ENSDARG00000005015
    fruit fly
    (Drosophila melanogaster)
    Insecta Set6
    Set
    30(a)
    1 → many
    3R(11089257-11090975)
    worm
    (Caenorhabditis elegans)
    Secernentea spr-26
    Protein SPR-2, isoform b (spr-2) mRNA, complete cd...
    24(a)
    1 → many
    IV(8891470-8892747) WBGene00005007


    ENSEMBL Gene Tree for TSPYL1 (if available)
    TreeFam Gene Tree for TSPYL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TSPYL1 gene
    SET2  TSPY6P2  TSPYL62  TSPY42  TSPY12  TSPY82  TSPYL22  TSPYL52  
    TSPYL42  TSPY102  TSPY22  TSPY32  
    14 SIMAP similar genes for TSPYL1 using alignment to 1 protein entry:     TSYL1_HUMAN:
    TSPYL    LOC728395    TSPYL6    TSPY8    TSPYL4    TSPY26P
    TSPY6P    TSPY10    TSPY3    TSPY4    TSPY1    TSPY2
    TSPYL2    TSPYL5

    TSPYL1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TSPYL1
    PGOHUM00000242463


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TSPYL1 (see all 203)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1903106291,2
    --116596877(+) GGTGGC/TGCATG 1 -- ds50010--------
    rs94888831,2
    C--116596923(+) agaatC/Tgcttg 1 -- ds50010--------
    rs1930515941,2
    --116596957(+) TGAGCA/GGAAGC 1 -- ds50010--------
    rs1387081151,2
    --116596974(+) TGAGCC/TGAGAT 1 -- ds50010--------
    rs752177111,2
    C,F--116596975(+) GAGCCA/GAGATG 1 -- ds50012Minor allele frequency- G:0.33WA CSA 3
    rs1847268151,2
    --116597008(+) GCAACA/TAGAGC 1 -- ds50010--------
    rs1879984271,2
    --116597009(+) CAACAA/GGAGCA 1 -- ds50010--------
    rs563594311,2
    C,F--116597235(+) ACCTTC/ATTTTT 1 -- ds50013Minor allele frequency- A:0.08WA CSA 122
    rs1808203881,2
    --116597494(+) TCAATA/CTGAAA 1 -- ut310--------
    rs1851775201,2
    --116597501(+) GAAAAA/TAATTG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TSPYL1 (116596022 - 116601280 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TSPYL1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv523972CNV Gain19592680

    Human Gene Mutation Database (HGMD): TSPYL1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TSPYL1
    DNA2.0 Custom Variant and Variant Library Synthesis for TSPYL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604714   
    OMIM disorders: 608800  
    UniProtKB/Swiss-Prot: TSYL1_HUMAN, Q9H0U9
  • Sudden infant death with dysgenesis of the testes syndrome (SIDDT) [MIM:608800]: Autosomal recessive
    disorder. Affected infants appear normal at birth, develop signs of visceroautonomic dysfunction early in life,
    and die before 12 months of age of abrupt cardiorespiratory arrest. Features included bradycardia, hypothermia,
    severe gastroesophageal reflux, laryngospasm, bronchospasm, and abnormal cardiorespiratory patterns during sleep.
    Genotypic males with SIDDT had fetal testicular dysgenesis and ambiguous genitalia, with findings such as
    intraabdominal testes, dysplastic testes, deficient fetal testosterone production, fusion and rugation of the
    gonadal sac, and partial development of the penile shaft. Female sexual development was normal. Affected infants
    had an unusual staccato cry, similar to the cry of a goat. Note=The disease is caused by mutations affecting the
    gene represented in this entry

  • 14 diseases for TSPYL1:    
    About MalaCards
    sudden infant death with dysgenesis of the testes syndrome    sudden infant death syndrome    intrahepatic cholangiocarcinoma    brain cancer
    male infertility    cholangiocarcinoma    azoospermia    infertility
    acute myeloid leukemia    myeloid leukemia    multiple myeloma    myeloma
    leukemia    prostatitis


    TSPYL1 for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for TSPYL1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sudden infant death syndrome 71.9 4 16418600 (2), 15273283 (1), 15833274 (1)
    congenital malformation 58 5 16418600 (2), 15833274 (2), 15273283 (1)
    death sudden 50 1 16418600 (1)

    Genetic Association Database (GAD): TSPYL1
    Human Genome Epidemiology (HuGE) Navigator: TSPYL1 (2 documents)

    Export disorders for TSPYL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TSPYL1 gene, integrated from 10 sources (see all 32):
    (articles sorted by number of sources associating them with TSPYL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Murine and human TSPYL genes: novel members of the TSPY-SET-NAP1L1 family. (PubMed id 9730615)1, 2, 3, 9 Vogel T....Schmidtke J. (Cytogenet. Cell Genet. 1998)
    2. Genetic investigation of the TSPYL1 gene in sudden infant death syndrome. (PubMed id 16418600)1, 4, 9 Hering R....Riess O. (Genet. Med. 2006)
    3. Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function. (PubMed id 15273283)1, 2, 9 Puffenberger E.G.... Stephan D.A. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    4. Mutations in the TSPYL1 gene associated with 46,XY disorder of sex development and male infertility. (PubMed id 19463995)1, 4 Vinci G....Bashamboo A. (Fertil. Steril. 2009)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    8. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    9. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. (PubMed id 23382074)1 Armour S.M....Sinclair D.A. (Mol. Cell. Biol. 2013)
    10. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7259 HGNC: 12382 Ensembl:ENSG00000189241 euGenes: HUgn7259 ECgene: TSPYL1
    H-InvDB: TSPYL1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TSPYL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TSPYL1 gene:
    Search GeneIP for patents involving TSPYL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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