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Aliases for TSPY10 Gene

Aliases for TSPY10 Gene

  • Testis Specific Protein, Y-Linked 10 2 3

External Ids for TSPY10 Gene

Previous GeneCards Identifiers for TSPY10 Gene

  • GC00U926456
  • GC0YP009365

Summaries for TSPY10 Gene

GeneCards Summary for TSPY10 Gene

TSPY10 (Testis Specific Protein, Y-Linked 10) is a Protein Coding gene. An important paralog of this gene is TSPY2.

UniProtKB/Swiss-Prot for TSPY10 Gene

  • Unknown. May be involved in sperm differentiation and proliferation (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSPY10 Gene

Genomics for TSPY10 Gene

Genomic Location for TSPY10 Gene

Start:
9,527,880 bp from pter
End:
9,530,683 bp from pter
Size:
2,804 bases
Orientation:
Plus strand

Genomic View for TSPY10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TSPY10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSPY10 Gene

No data available for Regulatory Elements for TSPY10 Gene

Proteins for TSPY10 Gene

  • Protein details for TSPY10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CW01-TSPYA_HUMAN
    Recommended name:
    Testis-specific Y-encoded protein 10
    Protein Accession:
    P0CW01
    Secondary Accessions:

    Protein attributes for TSPY10 Gene

    Size:
    314 amino acids
    Molecular mass:
    35727 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TSPY10 Gene

Proteomics data for TSPY10 Gene at MOPED

Post-translational modifications for TSPY10 Gene

No Post-translational modifications

Other Protein References for TSPY10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TSPY10 Gene

Domains for TSPY10 Gene

Protein Domains for TSPY10 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TSPY10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CW01

UniProtKB/Swiss-Prot:

TSPYA_HUMAN :
  • P0CW01
Family:
  • Belongs to the nucleosome assembly protein (NAP) family.
genes like me logo Genes that share domains with TSPY10: view

No data available for Gene Families for TSPY10 Gene

Function for TSPY10 Gene

Molecular function for TSPY10 Gene

UniProtKB/Swiss-Prot Function:
Unknown. May be involved in sperm differentiation and proliferation (By similarity).

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TSPY10 Gene

Localization for TSPY10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TSPY10 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TSPY10 Gene COMPARTMENTS Subcellular localization image for TSPY10 gene
Compartment Confidence
nucleus 5
cytosol 2
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TSPY10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with TSPY10: view

Pathways for TSPY10 Gene

SuperPathways for TSPY10 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TSPY10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006334 nucleosome assembly IEA --
GO:0007283 spermatogenesis IEA --
GO:0007506 gonadal mesoderm development IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with TSPY10: view

No data available for Pathways by source for TSPY10 Gene

Transcripts for TSPY10 Gene

mRNA/cDNA for TSPY10 Gene

(2) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TSPY10

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TSPY10 Gene

No ASD Table

Relevant External Links for TSPY10 Gene

GeneLoc Exon Structure for
TSPY10
ECgene alternative splicing isoforms for
TSPY10

Expression for TSPY10 Gene

mRNA expression in normal human tissues for TSPY10 Gene

mRNA differential expression in normal tissues according to GTEx for TSPY10 Gene

This gene is overexpressed in Testis (53.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TSPY10 Gene

genes like me logo Genes that share expressions with TSPY10: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for TSPY10 Gene

Orthologs for TSPY10 Gene

This gene was present in the common ancestor of animals.

Orthologs for TSPY10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC101059018 35
  • 88.74 (n)
  • 77.24 (a)
-- 36
  • 95 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 43 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 37 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 36 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
TSPY-M2 36
  • 35 (a)
ManyToMany
TSPY-M2 36
  • 41 (a)
ManyToMany
TSPY-M2 36
  • 41 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 25 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 26 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii TSPY2 36
  • 16 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Set 36
  • 26 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea spr-2 36
  • 20 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9132 36
  • 19 (a)
OneToMany
Species with no ortholog for TSPY10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TSPY10 Gene

ENSEMBL:
Gene Tree for TSPY10 (if available)
TreeFam:
Gene Tree for TSPY10 (if available)

Paralogs for TSPY10 Gene

Paralogs for TSPY10 Gene

Selected SIMAP similar genes for TSPY10 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with TSPY10: view

Variants for TSPY10 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for TSPY10 Gene

P0CW01-TSPYA_HUMAN
Maps to a tandemly repeated region on chromosome Yp11; additionally at least one copy is reported originating from Yq. The gene is thought to be present with an inter-individual variation in copy number and between 20 and 60 copies per Y chromosome are expected. 35 tandemly repeated gene copies on Yp11 originating from one individual have been reported (PubMed:12815422).

Sequence variations from dbSNP and Humsavar for TSPY10 Gene

SNP ID Clin Chr 0Y pos Sequence Context AA Info Type MAF
rs199621556 -- 9,529,367(+) AGTGG(A/G)AGGAA intron-variant
rs368030504 -- 9,530,413(+) ACATT(G/T)CAAAG intron-variant
rs368615634 -- 9,530,730(+) GTGTG(-/TC)TGTGT downstream-variant-500B
rs369584700 -- 9,530,801(+) TCTCT(G/T)CATGG downstream-variant-500B
rs370811737 -- 9,530,720(+) GTGTT(-/TG)TGTGT downstream-variant-500B

Relevant External Links for TSPY10 Gene

HapMap Linkage Disequilibrium report
TSPY10

No data available for Structural Variations from Database of Genomic Variants (DGV) for TSPY10 Gene

Disorders for TSPY10 Gene

(4) University of Copenhagen DISEASES for TSPY10 Gene

genes like me logo Genes that share disorders with TSPY10: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for TSPY10 Gene

Publications for TSPY10 Gene

  1. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. (PMID: 12815422) Skaletsky H. … Page D.C. (Nature 2003) 3 4
  2. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for TSPY10 Gene

Sources for TSPY10 Gene

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