Aliases for TSPAN8 Gene
External Ids for TSPAN8 Gene
Previous HGNC Symbols for TSPAN8 Gene
Previous GeneCards Identifiers for TSPAN8 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for TSPAN8 Gene
TSPAN8 (Tetraspanin 8) is a Protein Coding gene. Diseases associated with TSPAN8 include Autosomal Recessive Nonsyndromic Deafness 3. Among its related pathways are Extracellular vesicle-mediated signaling in recipient cells. An important paralog of this gene is TSPAN4.