Aliases for TSPAN7 Gene
External Ids for TSPAN7 Gene
Previous HGNC Symbols for TSPAN7 Gene
Previous GeneCards Identifiers for TSPAN7 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
GeneCards Summary for TSPAN7 Gene
TSPAN7 (Tetraspanin 7) is a Protein Coding gene. Diseases associated with TSPAN7 include Non-Syndromic X-Linked Intellectual Disability and Miliaria Rubra. Among its related pathways are Transmission across Chemical Synapses and Cell surface interactions at the vascular wall. An important paralog of this gene is ENSG00000250349.
UniProtKB/Swiss-Prot for TSPAN7 Gene
May be involved in cell proliferation and cell motility.