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TSPAN33 Gene

protein-coding   GIFtS: 50
GCID: GC07P128784

Tetraspanin 33
  See related disease
at
MalaCards
 

Aliases
for TSPAN33 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tetraspanin 331 2     tetraspanin-332
PEN2 3 5     tspan-332
Proerythroblast New Membrane2 3     Penumbra3
hPen2 3     Tspan-333
penumbra2     

External Ids:    HGNC: 287431   Entrez Gene: 3403482   Ensembl: ENSG000001584577   OMIM: 6101205   UniProtKB: Q86UF13   

Export aliases for TSPAN33 gene to outside databases

Previous GC identifers: GC07P128379 GC07P128571 GC07P123145


Summaries
for TSPAN33 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TSPAN33 Gene:
TSPAN33 (tetraspanin 33) is a protein-coding gene. Diseases associated with TSPAN33 include inflammatory bowel disease. An important paralog of this gene is CD151.

UniProtKB/Swiss-Prot: TSN33_HUMAN, Q86UF1
Function: Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid
progenitors (By similarity)




Genomic Views
for TSPAN33 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TSPAN33 gene promoter:
         STAT1   GATA-3   STAT1beta   NF-kappaB   Arnt   GATA-1   GATA-2   STAT1alpha   NF-kappaB1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TSPAN33 promoter sequence
   Search Chromatin IP Primers for TSPAN33

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSPAN33


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q32.1   Ensembl cytogenetic band:  7q32.1   HGNC cytogenetic band: 7q32.3

TSPAN33 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSPAN33 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P128784:  view genomic region     (about GC identifiers)

Start:
 128,784,712 bp from pter      End:
 128,809,534 bp from pter
Size:
 24,823 bases      Orientation:
 plus strand

1 alternative location:
Chr7+,CRA_TCAG 128,168,549-128,193,491     

Proteins
for TSPAN33 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TSN33_HUMAN, Q86UF1 (See protein sequence)
Recommended Name: Tetraspanin-33  
Size: 283 amino acids; 31538 Da
Subunit: Homodimer; disulfide-linked (By similarity)

Explore the universe of human proteins at neXtProt for TSPAN33: NX_Q86UF1

Explore proteomics data for TSPAN33 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn172
  • Modification sites at PhosphoSitePlus

    • See TSPAN33 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_848657.1  
    ENSEMBL proteins: 
     ENSP00000289407  

    TSPAN33 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TSPAN33

    TSPAN33 Antibody Products:

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    Novus Biologicals TSPAN33 Antibodies
    Abcam antibodies for TSPAN33
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    ThermoFisher Antibody for TSPAN33
    LSBio Antibodies in human, mouse, rat for TSPAN33

    TSPAN33 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for TSPAN33
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    Cloud-Clone Corp. ELISAs for TSPAN33
    Cloud-Clone Corp. CLIAs for TSPAN33

    Domains /
    Families
    for TSPAN33 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 HGNC Gene Families:
    TSPAN: Tetraspanins

    3 InterPro protein domains:
     IPR018499 Tetraspanin/Peripherin
     IPR000301 Tetraspanin
     IPR008952 Tetraspanin_EC2

    Graphical View of Domain Structure for InterPro Entry Q86UF1

    ProtoNet protein and cluster: Q86UF1

    1 Blocks protein domain: IPB000301 Transmembrane four family signature

    UniProtKB/Swiss-Prot: TSN33_HUMAN, Q86UF1
    Similarity: Belongs to the tetraspanin (TM4SF) family


    TSPAN33 for domains           About GeneDecksing


    Function
    for TSPAN33 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TSN33_HUMAN, Q86UF1
    Function: Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid
    progenitors (By similarity)

    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tspan33):

     hematopoietic system  immune system  tumorigenesis 

    TSPAN33 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tspan33tm1Stsa for TSPAN33

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TSPAN33
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TSPAN33

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TSPAN33
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TSPAN33

    miRNA
    Products:            		miRTarBase miRNAs that target TSPAN33:
    hsa-mir-10b-5p (MIRT047482), hsa-mir-10a-5p (MIRT047718), hsa-mir-484 (MIRT042265)

    Block miRNA regulation of human, mouse, rat TSPAN33 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSPAN33 (see all 29):
    hsa-miR-1287 hsa-miR-30c hsa-miR-875-3p hsa-miR-137 hsa-miR-30d hsa-miR-1265 hsa-miR-30a hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmid: TSPAN33 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for TSPAN33
    Predesigned siRNA for gene silencing in human, mouse, rat TSPAN33

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TSPAN33

    Clone
    Products:             		 OriGene clones in human, mouse for TSPAN33 (see all 6)
    OriGene ORF clones in mouse, rat for TSPAN33
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TSPAN33 (NM_178562)
    Sino Biological Human cDNA Clone for TSPAN33
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSPAN33
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPAN33

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for TSPAN33
    Browse ESI BIO Cell Lines and PureStem Progenitors for TSPAN33 
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPAN33


    Localization
    for TSPAN33 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TSN33_HUMAN, Q86UF1: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytoskeleton1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    TSPAN33 for ontologies           About GeneDecksing


    Pathways & Interactions
    for TSPAN33 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TSPAN33
    Interactions:

        Search GeneGlobe Interaction Network for TSPAN33

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for TSPAN33 (ENSP000002894074) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ITGA8ENSP000003673164STRING: ENSP00000367316
    ITGAXENSP000002682964STRING: ENSP00000268296
    ITGB2ENSP000003032424STRING: ENSP00000303242
    About this table

    Drugs & Compounds
    for TSPAN33 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TSPAN33 (TSN33)



    Transcripts
    for TSPAN33 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TSPAN33 gene: 
    NM_178562.3  

    Unigene Cluster for TSPAN33:

    Tetraspanin 33
    Hs.27267  [show with all ESTs]
    Unigene Representative Sequence: NM_178562
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000289407(uc003vop.2) ENST00000496963 ENST00000486685(uc003voq.2)

    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat TSPAN33 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSPAN33 (see all 29):
    hsa-miR-1287 hsa-miR-30c hsa-miR-875-3p hsa-miR-137 hsa-miR-30d hsa-miR-1265 hsa-miR-30a hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmid: TSPAN33 3' UTR sequence
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for TSPAN33
    Predesigned siRNA for gene silencing in human, mouse, rat TSPAN33
    Clone
    Products:             		 OriGene clones in human, mouse for TSPAN33 (see all 6)
    OriGene ORF clones in mouse, rat for TSPAN33
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TSPAN33 (NM_178562)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSPAN33
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPAN33
    Primer
    Products:            		OriGene qPCR primer pairs and template standards for TSPAN33
    OriGene qSTAR qPCR primer pairs in human, mouse for TSPAN33
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSPAN33
      QuantiTect SYBR Green Assays in human, mouse, rat TSPAN33
      QuantiFast Probe-based Assays in human, mouse, rat TSPAN33

    Additional mRNA sequence: 

    AF276891.1 AY236849.1 BC044244.1 

    5 DOTS entries:

    DT.315426  DT.315427  DT.100814132  DT.95160864  DT.40310326 

    Selected AceView cDNA sequences (see all 119):

    BM675347 AI217778 AA456896 AA827439 AW001670 AA768759 BM714582 AA917873 
    AI078627 AA631017 BX280316 BQ684452 W95735 CA309092 BP872796 AA485019 
    CR609044 BF724098 AA715038 AW026287 BX093063 AA232951 CA311002 BQ708420 

    GeneLoc Exon Structure


    Expression
    for TSPAN33 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TSPAN33 expression in normal human tissues (normalized intensities)      TSPAN33 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCTTGAATT
    TSPAN33 Expression
    About this image


    TSPAN33 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
     
     Liver (Hepatobiliary System)
     
     Kidney (Urinary System)
    TSPAN33 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    TSPAN33 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.27267

    UniProtKB/Swiss-Prot: TSN33_HUMAN, Q86UF1
    Tissue specificity: Predominantly expressed in erythroblasts

        Custom PCR Arrays for TSPAN33
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    QuantiFast Probe-based Assays in human, mouse, rat TSPAN33
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPAN33

    Orthologs
    for TSPAN33 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TSPAN33 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Tspan331 , 5 tetraspanin 331, 5 90.69(n)1
    96.82(a)1    		   6 (12.36 cM)5
    2326701  NM_146173.21  NP_666285.11 
     296942225 
    chicken
    (Gallus gallus)    		 Aves --
    		 Uncharacterized protein
    		 28(a)
    		 many ↔ many
    		 22(2867289-2901924) ENSGALG00000013528
    lizard
    (Anolis carolinensis)    		 Reptilia TSPAN336
    		 tetraspanin 33
    		 41(a)
    		 1 ↔ 1
    		 GL343993.1(98110-113242)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia tspan331 tetraspanin 33 75.44(n)
    83.99(a)    		   100487922  XM_002931844.2  XP_002931890.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii tspan331 tetraspanin 33 73.21(n)
    77.57(a)    		   436890  NM_001002617.1  NP_001002617.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Tsp86D1 Tetraspanin 86D 55.04(n)
    43.68(a)    		   41310  NM_001275539.1  NP_001262468.1 


    ENSEMBL Gene Tree for TSPAN33 (if available)
    TreeFam Gene Tree for TSPAN33 (if available)

    Paralogs
    for TSPAN33 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TSPAN33 gene
    CD1512  TSPAN52  TSPAN102  TSPAN172  TSPAN62  CD632  TSPAN32  TSPAN152  
    TSPAN72  TSPAN112  TSPAN142  ENSG000002503492  
    15 SIMAP similar genes for TSPAN33 using alignment to 1 protein entry:     TSN33_HUMAN:
    TM4SF17    TSPAN5    TM4SF9    TSPAN17    TSPAN15    TSPAN14
    CD63    TSPAN10    TSPAN6    TSPAN8    TM4SF2    TSPAN7
    CD151    CD82    TSPAN9

    TSPAN33 for paralogs           About GeneDecksing



    Genomic Variants
    for TSPAN33 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

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    Selected SNPs for TSPAN33 (see all 542)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1823860231,2
    		--128166584(+) CTAGCA/CAGGCA 1 -- us2k10--------
    rs1878256061,2
    		C--128166596(+) GGTGGC/TGGGCG 1 -- us2k10--------
    rs1125745461,2
    		C,F--128166659(+) GGAGGC/TGGAGG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs803181311,2
    		C--128166797(+) CTATC-/C/TTCCCC 1 -- us2k10--------
    rs2008548941,2
    		C--128166799(+) TATCC-/TCCCCG 1 -- us2k10--------
    rs2022432111,2
    		C--128166799(+) TATCCC/TCCCCG 1 -- us2k10--------
    rs1925060181,2
    		--128167008(+) ACCACA/TGCCTA 1 -- us2k10--------
    rs1444606721,2
    		--128167082(+) GTCTAC/TTACTC 1 -- us2k10--------
    rs1832189661,2
    		--128167089(+) ACTCCC/TAAATC 1 -- us2k10--------
    rs800153551,2
    		C--128167130(+) AGCAGA/CATGCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TSPAN33 (128784712 - 128809534 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TSPAN33:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1096622CNV Insertion17803354
    nsv831127CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TSPAN33
    DNA2.0 Custom Variant and Variant Library Synthesis for TSPAN33

    Disorders / Diseases
    for TSPAN33 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus    		 OMIM gene information: 610120    OMIM disorders: --

    1 disease for TSPAN33:    About MalaCards
    inflammatory bowel disease


    TSPAN33 for disorders           About GeneDecksing


    Export disorders for TSPAN33 gene to outside databases

    Publications
    for TSPAN33 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for TSPAN33 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TSPAN33)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The human Penumbra gene is mapped to a region on chromosome 7 frequently deleted in myeloid malignancies. (PubMed id 16213355)1, 2, 3 Chen Z.... Tsai S. (Cancer Genet. Cytogenet. 2005)
    2. Penumbra encodes a novel tetraspanin that is highly expressed in erythroid progenitors and promotes effective erythropoiesis. (PubMed id 17158226)1, 2 Heikens M.J.... Tsai S. (Blood 2007)
    3. The phylogenetic analysis of tetraspanins projects the evolution of cell-cell interactions from unicellular to multicellular organisms. (PubMed id 16242907)1, 3 Huang S....Xu A. (Genomics 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. TSPAN33 is a novel marker of activated and malignant B cells. (PubMed id 24211713)1 Luu V.P....Zlotnik A. (Clin. Immunol. 2013)
    6. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (Nature 2012)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    8. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1 Scherer S.W.... Tsui L.-C. (Science 2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Intron evolution: testing hypotheses of intron evolution using the phylogenomics of tetraspanins. (PubMed id 19262691)9 Garcia-EspaA+a A....Desalle R. (PLoS ONE 2009)

    External Searches for TSPAN33 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing TSPAN33 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 340348 HGNC: 28743 AceView: MGC50844 Ensembl:ENSG00000158457 euGenes: HUgn340348
    ECgene: TSPAN33 H-InvDB: TSPAN33

    Other Databases showing TSPAN33 gene

    (According to HUGE)
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    Specialized Databases showing TSPAN33 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TSPAN33 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TSPAN33 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    TryGeneCards Plus    		Patent Information for TSPAN33 gene:
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