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TSPAN32 Gene

protein-coding GIFtS: 50
GCID: GC11P002323

Tetraspanin 32

(Previous name: pan-hematopoietic expression)
(Previous symbols: TSSC6, PHEMX)

See TSPAN32-related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Tetraspanin 32¹ ²		Pan-Hematopoietic Expression Protein²
PHEMX¹ ² ³ ⁵		tetraspanin-32²
TSSC6¹ ² ³ ⁵		tspan-32²
Protein Phemx² ³		Tumor-Suppressing STF CDNA 6²
Pan-Hematopoietic Expression¹		Tumor-Suppressing Subchromosomal Transferable Fragment CDNA 6²
ART1²		Tumor-Suppressing Subtransferable Candidate 6²
PHMX²		Tspan-32³

External Ids:	HGNC: 13410¹	Entrez Gene: 10077²	Ensembl: ENSG00000064201⁷	OMIM: 603853⁵	UniProtKB: Q96QS1³

ORGUL members:

Export aliases for TSPAN32 gene to outside databases

Previous GC identifers: GC11P002280 GC11P002113

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TSPAN32 Gene:

This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable

fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region.

Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma,

adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted

genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes

imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also

involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their

biological validity has not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for TSPAN32 Gene:

TSPAN32 (tetraspanin 32) is a protein-coding gene. Diseases associated with TSPAN32 include wilms tumor, and malaria.

Gene Wiki entry for TSPAN32 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000011.9 NT_009237.19 NC_018922.2

Regulatory elements:

Regulatory transcription factor binding sites in the TSPAN32 gene promoter:
Elk-1 RP58 GATA-3 NCX/Ncx MyoD CREB GATA-6 deltaCREB HOXA5 TGIF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TSPAN32 promoter sequence

Search Chromatin IP Primers for TSPAN32

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSPAN32

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.5 HGNC cytogenetic band: 11p15

TSPAN32 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSPAN32 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P002323: view genomic region (about GC identifiers)

Start:	2,323,227 bp from pter	End:	2,339,430 bp from pter
Size:	16,204 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TSN32_HUMAN, Q96QS1 (See protein sequence)

Recommended Name: Tetraspanin-32

Size: 320 amino acids; 34631 Da

Developmental stage: Expressed from early embryogenesis through to adulthood

Secondary accessions: Q96KX4 Q9HC50 Q9HC51 Q9Y5U1

Alternative splicing: 5 isoforms: Q96QS1-1 Q96QS1-2 Q96QS1-3 Q96QS1-4 Q96QS1-5 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for TSPAN32: NX_Q96QS1

Explore proteomics data for TSPAN32 at MOPED

See TSPAN32 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_620591.3

ENSEMBL proteins:

ENSP00000405001 ENSP00000182290 ENSP00000395018 ENSP00000370513 ENSP00000343285

ENSP00000405205 ENSP00000370509

TSPAN32 Human Recombinant Protein Products:

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	antibodies-online proteins for TSPAN32 (3 products)
	antibodies-online peptides for TSPAN32

TSPAN32 Antibody Products:

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	antibodies-online antibodies for TSPAN32 (36 products)

TSPAN32 Assay Products:

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	Cloud-Clone Corp. ELISAs for TSPAN32 Cloud-Clone Corp. CLIAs for TSPAN32
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	antibodies-online kits for TSPAN32 (4 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

TSPAN: Tetraspanins

3 InterPro protein domains:

IPR018499 Tetraspanin/Peripherin

IPR000301 Tetraspanin

IPR008952 Tetraspanin_EC2

Graphical View of Domain Structure for InterPro Entry Q96QS1

ProtoNet protein and cluster: Q96QS1

UniProtKB/Swiss-Prot: TSN32_HUMAN, Q96QS1

Similarity: Belongs to the tetraspanin (TM4SF) family

Find genes that share domains with TSPAN32 About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

Find genes that share ontologies with TSPAN32 About GenesLikeMe

Phenotypes:
2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tspan32):

hematopoietic system

immune system

Find genes that share phenotypes with TSPAN32 About GenesLikeMe

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for TSPAN32

miRNA Products:		Block miRNA regulation of human, mouse, rat TSPAN32 using miScript Target Protectors
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Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for TSPAN32
		Predesigned siRNA for gene silencing in human, mouse, rat TSPAN32

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for TSPAN32

Clone Products:		OriGene clones in human, mouse for TSPAN32 (see all 9) OriGene ORF clones in mouse, rat for TSPAN32 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TSPAN32 (NM_139022)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPAN32

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

TSN32_HUMAN, Q96QS1: Membrane; Multi-pass membrane protein (Potential)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
extracellular	3
plasma membrane	2
golgi apparatus	1
nucleus	1

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Gene Ontology (GO): 4 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0009986	cell surface	IEA	--
GO:0016021	integral component of membrane	--	--
GO:0070442	alphaIIb-beta3 integrin complex	IEA	--

Find genes that share ontologies with TSPAN32 About GenesLikeMe

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for TSPAN32
Interactions:

Search GeneGlobe Interaction Network for TSPAN32

Gene Ontology (GO): Selected biological process terms (see all 10): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007010	cytoskeleton organization	IEA	--
GO:0007229	integrin-mediated signaling pathway	IEA	--
GO:0007267	cell-cell signaling	TAS	10950922
GO:0007596	blood coagulation	--	--
GO:0007599	hemostasis	--	--

Find genes that share ontologies with TSPAN32 About GenesLikeMe

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for TSPAN32 (TSN32)

7 Novoseek inferred chemical compound relationships for TSPAN32 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
ganglioside	44.3	4	15334254 (1), 12068006 (1), 15710618 (1), 19559406 (1)
tyrosine	31	6	10427099 (1), 12938224 (1), 12110679 (1), 19166707 (1) (see all 5)
lipid	27.3	9	15454569 (1), 15496196 (1), 16785325 (1), 19497983 (1) (see all 9)
phosphatidylinositol	23.4	2	12110679 (1), 11739647 (1)
cysteine	23.2	5	20171294 (2), 11907260 (1), 14556650 (1), 12575999 (1)
cholesterol	5.22	23	12938224 (5), 15184367 (2), 15454569 (1), 19497983 (1) (see all 5)
polysaccharide	0	1	12701754 (1)

Find genes that share compounds with TSPAN32 About GenesLikeMe

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for TSPAN32 gene (3 alternative transcripts):

NM_139022.2 NM_005705.4 NM_139024.3

Unigene Cluster for TSPAN32:

Tetraspanin 32

Hs.271954 [show with all ESTs]

Unigene Representative Sequence: AK298692

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000437313 ENST00000461200(uc001lvx.1 uc009ydk.1 uc010qxk.2 uc001lvy.1 uc009ydl.1 uc001lwb.1 uc001lwc.1 uc001lwd.1)

ENST00000182290 ENST00000446063 ENST00000493924 ENST00000484104 ENST00000479508

ENST00000498313 ENST00000483227 ENST00000381121 ENST00000493948 ENST00000339046

ENST00000451520(uc001lvz.1) ENST00000381117 ENST00000484523 ENST00000486011

miRNA Products:		Block miRNA regulation of human, mouse, rat TSPAN32 using miScript Target Protectors
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Primer Products:		OriGene qPCR primer pairs and template standards for TSPAN32 OriGene qSTAR qPCR primer pairs in human, mouse for TSPAN32
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Additional mRNA sequence:

AF176071.1 AK298692.1 AK307638.1 AK310116.1 AY039001.1 AY303780.1 BC016693.1

11 DOTS entries:

DT.95168325 DT.111418 DT.95094062 DT.111419 DT.91648803 DT.97812022 DT.91656368 DT.120684722

DT.95168321 DT.95168322 DT.40314344

Selected AceView cDNA sequences (see all 49):

CR606621 NM_139022 AF176070 AW440888 AY039001 NM_139024 BX117724 BI906333

AA701395 BF512909 AA694062 BM926073 BV196160 BC016693 BG506933 AF125569

AY303780 AF176071 AK128812 BI909345 BI907377 N99620 AA777339 AA913945

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for TSPAN32 (see all 12) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	·	2c	·	2d	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	^	10	^	11	^	12	^	13	^	14a	·	14b	·	14c
SP1:					-		-		-						-				-										-		-		-
SP2:					-		-		-						-				-										-		-		-				-
SP3:															-				-						-				-		-		-
SP4:															-				-										-		-		-
SP5:															-				-		-								-		-		-

ECgene alternative splicing isoforms for TSPAN32

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TSPAN32 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GCTGTAGGAC

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TSPAN32 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 5) fully expand


Blood (Cardiovascular System) fully expand to see all 2 entries
Hematopoietic Stem Cells Hematopoietic Bone Marrow

Liver (Hepatobiliary System)
Hematopoietic Stem Cells Liver Bud

Bone (Muscoskeletal System)
Chondrocytes Zeugopod Epiphyseal End

Cartilage (Muscoskeletal System)
Chondrocytes Zeugopod Epiphyseal End

Spleen (Hematopoietic System)

TSPAN32 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

TSPAN32 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.271954

UniProtKB/Swiss-Prot: TSN32_HUMAN, Q96QS1

Tissue specificity: Expressed ubiquitously at low levels. High levels of expression are confined to hematopoietic

tissues including peripheral blood leukocytes, thymus and spleen

Custom PCR Arrays for TSPAN32

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPAN32

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for TSPAN32 gene from Selected species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tspan32^{1 , 5}	tetraspanin 32^{1, 5}	76.02(n)¹ 64.03(a)¹		7 (88.09 cM)⁵ 27027¹ NM_001128080.2¹ NP_001121552.1¹ 143005046⁵
chicken (Gallus gallus)	Aves	TSPAN32¹	tetraspanin 32	60.54(n) 46.58(a)		395087 XM_004941440.1 XP_004941497.1
lizard (Anolis carolinensis)	Reptilia	TSPAN32⁶	tetraspanin 32	52(a)	1 ↔ 1	1(69690114-69698244)
tropical clawed frog (Xenopus tropicalis)	Amphibia	tspan32¹	tetraspanin 32	46.58(n) 32.22(a)		100489691 XM_002938903.2 XP_002938949.2

ENSEMBL Gene Tree for TSPAN32 (if available)
TreeFam Gene Tree for TSPAN32 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for TSPAN32 gene

1 SIMAP similar gene for TSPAN32 using alignment to 5 protein entries: TSN32_HUMAN (see all proteins):

PHEMX

Find genes that share paralogs with TSPAN32 About GenesLikeMe

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs183338409^1,2		--	2325165(+)	`AGTCCC/TACCTC`	1	--	int¹		0	--	--	--	--
rs117600357^1,2	C,F	--	2325192(+)	`GGGCCG/ATCTGA`	1	--	int¹		1		NA	120
rs2234295^1,2	C,F	--	2325239(+)	`CCTCAC/TGGCCC`	1	--	int¹		1		NA	120
rs202189471^1,2	C	--	2325290(+)	`TCAGGA/GCCTGT`	1	--	int¹		0	--	--	--	--
rs201530910^1,2		--	2325347(+)	`TCTGCA/GGGGTT`	2	A	syn¹		0	--	--	--	--
rs200631781^1,2		--	2325378(+)	`CTCTGA/GGAGCC`	2	R G	mis¹		0	--	--	--	--
rs2234296^1,2	C,F,H	--	2325384(+)	`GAGCCG/ATGCTG`	2	/M /V	mis¹ ese³		8		NS EA CSA NA EU	4985
rs199650987^1,2		--	2325392(+)	`CTGAGC/TGCTGC`	2	S	syn¹		0	--	--	--	--
rs201634419^1,2	C	--	2325393(+)	`TGAGCA/GCTGCA`	2	T A	mis¹		0	--	--	--	--
rs200624662^1,2	C	--	2325414(+)	`GGGAGG/TCCCAG`	2	A S	mis¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TSPAN32 (2323227 - 2339430 bp)

Structural Variations
Database of Genomic Variants (DGV) Selected variations for TSPAN32 (see all 12): About this table

Variant ID	Type	Subtype	PubMed ID
esv2744004	CNV	Deletion	23290073
esv2744005	CNV	Deletion	23290073
esv2744003	CNV	Deletion	23290073
esv1338872	CNV	Deletion	17803354
nsv896801	CNV	Loss	21882294
dgv999n71	CNV	Loss	21882294
nsv469928	CNV	Loss	18288195
nsv896806	CNV	Loss	21882294
nsv896776	CNV	Loss	21882294
nsv896804	CNV	Loss	21882294

Site Specific Mutation Identification with PCR Assays

Search QIAGEN SeqTarget long-range PCR primers for resequencing TSPAN32

DNA2.0 Custom Variant and Variant Library Synthesis for TSPAN32

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 603853 OMIM disorders: --

5 diseases for TSPAN32:
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wilms tumor malaria beckwith-wiedemann syndrome adrenocortical carcinoma

alveolar echinococcosis

1 inferred disease relationship from the University of Copenhagen DISEASES database for TSPAN32:

Beckwith-Wiedemann syndrome

Find genes that share disorders with TSPAN32 About GenesLikeMe

Selected Novoseek inferred disease relationships for TSPAN32 gene (see all 24) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
metastasis	52.3	50	16823699 (3), 19078974 (3), 19363832 (2), 16467180 (2) (see all 33)
hepatitis c	39.2	10	11226150 (2), 15449903 (1), 11134943 (1), 18836553 (1) (see all 9)
cancer	37.4	19	15205336 (1), 16823699 (1), 16944980 (1), 18395972 (1) (see all 16)
pathological processes	32.1	4	19251723 (1), 19703604 (1), 16404722 (1), 16467180 (1)
tumors	30.6	25	12579280 (2), 15205336 (1), 15533898 (1), 16823699 (1) (see all 22)
primary tumor	25.7	5	16467180 (2), 16404722 (1), 17582603 (1)
myeloma	23.9	2	18804164 (1), 16113057 (1)
colon cancer	23	4	16467180 (2), 16404722 (1)
immunodeficiency	16.7	4	16775336 (1), 18836553 (1), 17522207 (1), 19458002 (1)
schistosomiasis	11.1	2	9756983 (1), 17222846 (1)

Export disorders for TSPAN32 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for TSPAN32 gene, integrated from 10 sources (see all 228):
(articles sorted by number of sources associating them with TSPAN32)

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Phemx, a novel mouse gene expressed in hematopoietic cells maps to the imprinted cluster on distal chromosome 7. (PubMed id 10950922)^{1, 2, 3, 9} Nicholson R.H.... Ko M.S.H. (Genomics 2000)
Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting. (PubMed id 10072438)^{1, 2, 3, 9} Lee M.P....Feinberg A.P. (Hum. Mol. Genet. 1999)
Molecular characterisation of mouse and human TSSC6: evidence that TSSC6 is a genuine member of the tetraspanin superfamily and is expressed specifically in haematopoietic organs. (PubMed id 11718897)^{1, 2, 9} Robb L....Wright M.D. (Biochim. Biophys. Acta 2001)
An unappreciated role for RNA surveillance. (PubMed id 14759258)^{1, 2} Hillman R.T.... Brenner S.E. (Genome Biol. 2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. (PubMed id 23770605)¹ Berndt S.I....Slager S.L. (Nat. Genet. 2013)
A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity. (PubMed id 20709950)¹ Gartlan K.H....Wright M.D. (J. Immunol. 2010)
Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins. (PubMed id 17192395)¹ Macaulay I.C....Ouwehand W.H. (Blood 2007)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse. (PubMed id 10915772)¹ Paulsen M....Walter J. (Hum. Mol. Genet. 2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10077	HGNC: 13410	AceView: PHEMX	Ensembl:ENSG00000064201	euGenes: HUgn10077
ECgene: TSPAN32	H-InvDB: TSPAN32

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TSPAN32	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for TSPAN32	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for TSPAN32 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TSPAN32 gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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