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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TSPAN32 Gene

protein-coding GIFtS: 49
GCID: GC11P002323

Tetraspanin 32

(Previous name: pan-hematopoietic expression)
(Previous symbols: TSSC6, PHEMX)

Microbiology & Infectious Diseases Congress

34 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Tetraspanin 32¹ ²		Pan-Hematopoietic Expression Protein²
PHEMX¹ ² ³ ⁵		tetraspanin-32²
TSSC6¹ ² ³ ⁵		tspan-32²
Protein Phemx² ³		Tumor-Suppressing STF CDNA 6²
Pan-Hematopoietic Expression¹		Tumor-Suppressing Subchromosomal Transferable Fragment CDNA 6²
ART1²		Tumor-Suppressing Subtransferable Candidate 6²
PHMX²		Tspan-32³

External Ids:	HGNC: 13410¹	Entrez Gene: 10077²	Ensembl: ENSG00000064201⁷	OMIM: 603853⁵	UniProtKB: Q96QS1³

Export aliases for TSPAN32 gene to outside databases

Previous GC identifers: GC11P002280 GC11P002113

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TSPAN32 Gene:

This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable

fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region.

Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma,

adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes;

however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This

gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic

cell function. Alternatively spliced transcript variants have been described, but their biological validity has not

been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for TSPAN32 Gene:

TSPAN32 (tetraspanin 32) is a protein-coding gene. Diseases associated with TSPAN32 include adrenocortical carcinoma, and mental retardation epilepsy. GO annotations related to this gene include molecular_function.

Gene Wiki entry for TSPAN32 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NT_009237.18 NC_018922.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TSPAN32 gene promoter:
Elk-1 RP58 GATA-3 NCX/Ncx MyoD CREB GATA-6 deltaCREB HOXA5 TGIF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TSPAN32 promoter sequence

Search SABiosciences Chromatin IP Primers for TSPAN32

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSPAN32

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.5 HGNC cytogenetic band: 11p15

TSPAN32 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSPAN32 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P002323: view genomic region (about GC identifiers)

Start:	2,323,227 bp from pter	End:	2,339,430 bp from pter
Size:	16,204 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TSN32_HUMAN, Q96QS1 (See protein sequence)

Recommended Name: Tetraspanin-32

Size: 320 amino acids; 34631 Da

Subcellular location: Membrane; Multi-pass membrane protein (Potential)

Developmental stage: Expressed from early embryogenesis through to adulthood

Secondary accessions: Q96KX4 Q9HC50 Q9HC51 Q9Y5U1

Alternative splicing: 5 isoforms: Q96QS1-1 Q96QS1-2 Q96QS1-3 Q96QS1-4 Q96QS1-5 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for TSPAN32: NX_Q96QS1

Explore proteomics data for TSPAN32 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q96QS1

TSPAN32 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_620591.3

ENSEMBL proteins:

ENSP00000405001 ENSP00000182290 ENSP00000395018 ENSP00000370513 ENSP00000343285

ENSP00000405205 ENSP00000370509

Human Recombinant Protein Products for TSPAN32:

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	Cloud-Clone Corp. Proteins for TSPAN32

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0009986	cell surface	IEA	--
GO:0016021	integral to membrane	NAS	--
GO:0070442	alphaIIb-beta3 integrin complex	IEA	--

TSPAN32 for ontologies About GeneDecksing

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

TSPAN: Tetraspanins

3 InterPro protein domains:

IPR018499 Tetraspanin/Peripherin

IPR000301 Tetraspanin

IPR008952 Tetraspanin_EC2

Graphical View of Domain Structure for InterPro Entry Q96QS1

ProtoNet protein and cluster: Q96QS1

UniProtKB/Swiss-Prot: TSN32_HUMAN, Q96QS1

Similarity: Belongs to the tetraspanin (TM4SF) family

TSPAN32 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

TSPAN32 for ontologies About GeneDecksing

Phenotypes:
3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tspan32):

cellular

hematopoietic system

immune system

TSPAN32 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for TSPAN32

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TSPAN32

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPAN32

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TSPAN32

Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007010	cytoskeleton organization	IEA	--
GO:0007229	integrin-mediated signaling pathway	IEA	--
GO:0007267	cell-cell signaling	TAS	10950922
GO:0007596	blood coagulation	--	--
GO:0007599	hemostasis	--	--

TSPAN32 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

TSPAN32 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TSPAN32 (TSN32)

7 Novoseek inferred chemical compound relationships for TSPAN32 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
ganglioside	44.3	4	15334254 (1), 12068006 (1), 15710618 (1), 19559406 (1)
tyrosine	31	6	10427099 (1), 12938224 (1), 12110679 (1), 19166707 (1) (see all 5)
lipid	27.3	9	15454569 (1), 15496196 (1), 16785325 (1), 19497983 (1) (see all 9)
phosphatidylinositol	23.4	2	12110679 (1), 11739647 (1)
cysteine	23.2	5	20171294 (2), 11907260 (1), 14556650 (1), 12575999 (1)
cholesterol	5.22	23	12938224 (5), 15184367 (2), 15454569 (1), 19497983 (1) (see all 5)
polysaccharide	0	1	12701754 (1)

Search CenterWatch for drugs/clinical trials and news about TSPAN32 / TSN32

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TSPAN32 gene (3 alternative transcripts):

NM_139022.2 NM_005705.4 NM_139024.3

Unigene Cluster for TSPAN32:

Tetraspanin 32

Hs.271954 [show with all ESTs]

Unigene Representative Sequence: AK298692

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000437313 ENST00000461200(uc001lvx.1 uc009ydk.1 uc010qxk.2 uc001lvy.1 uc009ydl.1 uc001lwb.1 uc001lwc.1 uc001lwd.1)

ENST00000182290 ENST00000446063 ENST00000493924 ENST00000484104 ENST00000479508

ENST00000498313 ENST00000483227 ENST00000381121 ENST00000493948 ENST00000339046

ENST00000451520(uc001lvz.1) ENST00000381117 ENST00000484523 ENST00000486011

Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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Additional mRNA sequence:

AF176071.1 AK298692.1 AK307638.1 AK310116.1 AY039001.1 AY303780.1 BC016693.1

11 DOTS entries:

DT.95168325 DT.111418 DT.95094062 DT.111419 DT.91648803 DT.97812022 DT.91656368 DT.120684722

DT.95168321 DT.95168322 DT.40314344

24/49 AceView cDNA sequences (see all 49):

AF176070 NM_139022 AA701395 CR606621 AY039001 AW440888 BI906333 NM_139024

BX117724 N99620 BI909447 AA694062 AA777339 BE243068 AF176071 BG506933

BI909345 AY303780 NM_005705 AA913945 AK128812 BI907377 BC016693 BV196160

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for TSPAN32 (see all 12) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	·	2c	·	2d	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	^	10	^	11	^	12	^	13	^	14a	·	14b	·	14c
SP1:					-		-		-						-				-										-		-		-
SP2:					-		-		-						-				-										-		-		-				-
SP3:															-				-						-				-		-		-
SP4:															-				-										-		-		-
SP5:															-				-		-								-		-		-

ECgene alternative splicing isoforms for TSPAN32

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TSPAN32 expression in normal human tissues (normalized intensities) TSPAN32 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GCTGTAGGAC

About this image

TSPAN32 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/6 selected tissues (see all 6) fully expand


Blood (Cardiovascular System) fully expand to see all 3 entries
cd8+ t cell

Umbilical Cord (Extraembryonic Tissues)
cord blood

Inner Cell Mass (Early Embryo)
Blimp1- mVenus and stella-ECFP genetically modified stem cells

Bone (Muscoskeletal System)
Chondrocytes Zeugopod Epiphyseal End

Cartilage (Muscoskeletal System)
Chondrocytes Zeugopod Epiphyseal End

See TSPAN32 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TSPAN32

SOURCE GeneReport for Unigene cluster: Hs.271954

UniProtKB/Swiss-Prot: TSN32_HUMAN, Q96QS1

Tissue specificity: Expressed ubiquitously at low levels. High levels of expression are confined to hematopoietic

tissues including peripheral blood leukocytes, thymus and spleen

SABiosciences Custom PCR Arrays for TSPAN32

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for TSPAN32 gene from 3/8 species (see all 8) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tspan32^{1 , 5}	tetraspanin 32^{1, 5}	76.02(n)¹ 64.03(a)¹		7 (88.09 cM)⁵ 27027¹ NM_001128080.2¹ NP_001121552.1¹ 143005046⁵
chicken (Gallus gallus)	Aves	TSPAN32¹	tetraspanin 32	59.82(n) 47.49(a)		395087 XM_421025.2 XP_421025.2
lizard (Anolis carolinensis)	Reptilia	TSPAN32⁶	Uncharacterized protein	52(a)	1 ↔ 1	1(69690114-69698244)

ENSEMBL Gene Tree for TSPAN32 (if available)
TreeFam Gene Tree for TSPAN32 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TSPAN32 gene

1 SIMAP similar gene for TSPAN32 using alignment to 5 protein entries: TSN32_HUMAN (see all proteins):

PHEMX

TSPAN32 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs183338409^1,2		--	2325165(+)	`AGTCCC/TACCTC`	1	--	int¹		0	--	--	--	--
rs117600357^1,2	C,F	--	2325192(+)	`GGGCCG/ATCTGA`	1	--	int¹		1		NA	120
rs2234295^1,2	C,F	--	2325239(+)	`CCTCAC/TGGCCC`	1	--	int¹		1		NA	120
rs202189471^1,2	C	--	2325290(+)	`TCAGGA/GCCTGT`	1	--	int¹		0	--	--	--	--
rs201530910^1,2		--	2325347(+)	`TCTGCA/GGGGTT`	2	A	syn¹		0	--	--	--	--
rs200631781^1,2		--	2325378(+)	`CTCTGA/GGAGCC`	2	R G	mis¹		0	--	--	--	--
rs2234296^1,2	C,F,H	--	2325384(+)	`GAGCCG/ATGCTG`	2	/M /V	mis¹ ese³		8		NS EA CSA NA EU	4985
rs199650987^1,2		--	2325392(+)	`CTGAGC/TGCTGC`	2	S	syn¹		0	--	--	--	--
rs201634419^1,2	C	--	2325393(+)	`TGAGCA/GCTGCA`	2	T A	mis¹		0	--	--	--	--
rs200624662^1,2	C	--	2325414(+)	`GGGAGG/TCCCAG`	2	A S	mis¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TSPAN32 (2323227 - 2339430 bp)

Structural Variations
Database of Genomic Variants (DGV) 10/12 variations for TSPAN32 (see all 12): About this table

Variant ID	Type	Subtype	PubMed ID
esv2744004	CNV	Deletion	23290073
esv2744005	CNV	Deletion	23290073
esv2744003	CNV	Deletion	23290073
esv1338872	CNV	Deletion	17803354
nsv896801	CNV	Loss	21882294
dgv999n71	CNV	Loss	21882294
nsv469928	CNV	Loss	18288195
nsv896806	CNV	Loss	21882294
nsv896776	CNV	Loss	21882294
nsv896804	CNV	Loss	21882294

SABiosciences Cancer Mutation PCR Assays

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TSPAN32 for disorders           About GeneDecksing

OMIM gene information: 603853    OMIM disorders: --

20/34 diseases for TSPAN32 (see all 34):    About MalaCards

adrenocortical carcinoma mental retardation epilepsy beckwith-wiedemann syndrome alveolar echinococcosis

echinococcosis disseminated intravascular coagulation epilepsy syndrome schistosomiasis

merkel cell carcinoma wilms tumor rhabdomyosarcoma diphtheria

myeloma retinal degeneration eczema breast cancer

hepatitis c multiple myeloma oral squamous cell carcinoma lung cancer

1 disease from the University of Copenhagen DISEASES database for TSPAN32:

Beckwith-Wiedemann syndrome

Congresses - knowledge worth sharing:
The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

10/24 Novoseek inferred disease relationships for TSPAN32 gene (see all 24) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
metastasis	52.3	50	16823699 (3), 19078974 (3), 19363832 (2), 16467180 (2) (see all 33)
hepatitis c	39.2	10	11226150 (2), 15449903 (1), 11134943 (1), 18836553 (1) (see all 9)
cancer	37.4	19	15205336 (1), 16823699 (1), 16944980 (1), 18395972 (1) (see all 16)
pathological processes	32.1	4	19251723 (1), 19703604 (1), 16404722 (1), 16467180 (1)
tumors	30.6	25	12579280 (2), 15205336 (1), 15533898 (1), 16823699 (1) (see all 22)
primary tumor	25.7	5	16467180 (2), 16404722 (1), 17582603 (1)
myeloma	23.9	2	18804164 (1), 16113057 (1)
colon cancer	23	4	16467180 (2), 16404722 (1)
immunodeficiency	16.7	4	16775336 (1), 18836553 (1), 17522207 (1), 19458002 (1)
schistosomiasis	11.1	2	9756983 (1), 17222846 (1)

Export disorders for TSPAN32 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TSPAN32 gene, integrated from 9 sources (see all 227):
(articles sorted by number of sources associating them with TSPAN32)

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Phemx, a novel mouse gene expressed in hematopoietic cells maps to the imprinted cluster on distal chromosome 7. (PubMed id 10950922)^{1, 2, 3, 9} Nicholson R.H.... Ko M.S.H. (2000)
Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting. (PubMed id 10072438)^{1, 2, 3, 9} Lee M.P....Feinberg A.P. (1999)
Molecular characterisation of mouse and human TSSC6: evidence that TSSC6 is a genuine member of the tetraspanin superfamily and is expressed specifically in haematopoietic organs. (PubMed id 11718897)^{1, 2, 9} Robb L....Wright M.D. (2001)
An unappreciated role for RNA surveillance. (PubMed id 14759258)^{1, 2} Hillman R.T.... Brenner S.E. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A complementary role for the tetraspanins CD37 and Ts sc6 in cellular immunity. (PubMed id 20709950)¹ Gartlan K.H....Wright M.D. (2010)
Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins. (PubMed id 17192395)¹ Macaulay I.C....Ouwehand W.H. (2007)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse. (PubMed id 10915772)¹ Paulsen M....Walter J. (2000)
A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes. (PubMed id 9403053)¹ Hu R.-J.... Feinberg A.P. (1997)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 10077	HGNC: 13410	AceView: PHEMX	Ensembl:ENSG00000064201	euGenes: HUgn10077
ECgene: TSPAN32	H-InvDB: TSPAN32

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TSPAN32	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for TSPAN32	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for TSPAN32 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TSPAN32 gene:
Search GeneIP for patents involving TSPAN32

GeneCards and IP:
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