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TSPAN3 Gene

protein-coding   GIFtS: 53
GCID: GC15M077336

Tetraspanin 3

(Previous name: transmembrane 4 superfamily member 8)
(Previous symbol: TM4SF8)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tetraspanin 31 2     TSPAN-32
Transmembrane 4 Superfamily Member 81 2 3     Tetraspan 32
TM4SF81 2 3     Tetraspan TM4SF2
Tetraspanin TM4-A2 3     tetraspanin-32
TM4-A2     Tspan-33

External Ids:    HGNC: 177521   Entrez Gene: 100992   Ensembl: ENSG000001403917   OMIM: 6131345   UniProtKB: O606373   

Export aliases for TSPAN3 gene to outside databases

Previous GC identifers: GC15M075126 GC15M075127 GC15M054093


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TSPAN3 Gene:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin
family. Most of these members are cell-surface proteins that are characterized by the presence of four
hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell
development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this
gene. Multiple alternative transcripts encoding different isoforms have been described. (provided by RefSeq, Dec
2009)

GeneCards Summary for TSPAN3 Gene:
TSPAN3 (tetraspanin 3) is a protein-coding gene. An important paralog of this gene is CD151.

UniProtKB/Swiss-Prot: TSN3_HUMAN, O60637
Function: Regulates the proliferation and migration of oligodendrocytes, a process essential for normal
myelination and repair (By similarity)

Gene Wiki entry for TSPAN3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the TSPAN3 gene promoter:
         SREBP-1c   Nkx2-5   SREBP-1b   Evi-1   GATA-1   C/EBPalpha   MZF-1   SREBP-1a   IRF-7A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTSPAN3 promoter sequence
   Search Chromatin IP Primers for TSPAN3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSPAN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q24.3   Ensembl cytogenetic band:  15q24.3   HGNC cytogenetic band: 15q23

TSPAN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSPAN3 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M077336:  view genomic region     (about GC identifiers)

Start:
77,336,359 bp from pter      End:
77,376,326 bp from pter
Size:
39,968 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TSN3_HUMAN, O60637 (See protein sequence)
Recommended Name: Tetraspanin-3  
Size: 253 amino acids; 28018 Da
Subunit: Interacts with claudin-11/CLDN11 and integrins (By similarity)
Secondary accessions: A6NEH4 B3KQQ2 B4DP19 Q9BW22 Q9NVX9
Alternative splicing: 3 isoforms:  O60637-1   O60637-2   O60637-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TSPAN3: NX_O60637

Explore proteomics data for TSPAN3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys124
  • Glycosylation2 at Asn127, Asn152, Asn167, Asn183
  • Modification sites at PhosphoSitePlus

  • See TSPAN3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001161884.1  NP_005715.1  NP_944492.1  

    ENSEMBL proteins: 
     ENSP00000267970   ENSP00000341329   ENSP00000407243   ENSP00000453613   ENSP00000452835  
     ENSP00000453868  

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    Novus Biologicals TSPAN3 Protein
    Novus Biologicals TSPAN3 Lysate
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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for TSPAN3

     
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    antibodies-online proteins for TSPAN3 (5 products) 

     
    antibodies-online peptides for TSPAN3

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    antibodies-online antibodies for TSPAN3 (33 products) 

    TSPAN3 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TSPAN: Tetraspanins

    4 InterPro protein domains:
     IPR018499 Tetraspanin/Peripherin
     IPR000301 Tetraspanin
     IPR008952 Tetraspanin_EC2
     IPR018503 Tetraspanin_CS

    Graphical View of Domain Structure for InterPro Entry O60637

    ProtoNet protein and cluster: O60637

    1 Blocks protein domain: IPB000301 Transmembrane four family signature

    UniProtKB/Swiss-Prot: TSN3_HUMAN, O60637
    Similarity: Belongs to the tetraspanin (TM4SF) family


    Find genes that share domains with TSPAN3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TSN3_HUMAN, O60637
    Function: Regulates the proliferation and migration of oligodendrocytes, a process essential for normal
    myelination and repair (By similarity)

    Animal Models:

       genOway: Develop your customized and physiologically relevant rodent model for TSPAN3

    miRNA
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    miRTarBase miRNAs that target TSPAN3:
    hsa-let-7f-5p (MIRT051380), hsa-mir-155-5p (MIRT020952), hsa-mir-16-5p (MIRT031979), hsa-mir-15b-5p (MIRT046454), hsa-let-7b-5p (MIRT052340), hsa-mir-484 (MIRT041737), hsa-mir-197-3p (MIRT000215), hsa-let-7a-5p (MIRT052616), hsa-mir-26b-5p (MIRT030069)

    Block miRNA regulation of human, mouse, rat TSPAN3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSPAN3 (see all 65):
    hsa-miR-21* hsa-miR-323-3p hsa-miR-142-5p hsa-miR-136 hsa-miR-607 hsa-miR-1197 hsa-miR-1914* hsa-miR-199a-3p
    SwitchGear 3'UTR luciferase reporter plasmidTSPAN3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TSPAN3

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    GenScript: all cDNA clones in your preferred vector: TSPAN3 (NM_005981)
    Sino Biological Human cDNA Clone for TSPAN3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSPAN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPAN3

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TSN3_HUMAN, O60637: Membrane; Multi-pass membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    golgi apparatus1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with TSPAN3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TSPAN3
    Interactions:

        Search GeneGlobe Interaction Network for TSPAN3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    Selected Interacting proteins for TSPAN3 (O606372, 3 ENSP000002679704) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLDN11O755083, ENSP000000647244I2D: score=2 STRING: ENSP00000064724
    EWSR1Q018443, ENSP000003810314I2D: score=3 STRING: ENSP00000381031
    ITGB1P055563I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    --Q9BWA23, 2MINT-67828 I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TSPAN3 (TSN3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TSPAN3 gene (3 alternative transcripts): 
    NM_001168412.1  NM_005724.5  NM_198902.2  

    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000267970(uc002bcj.3 uc002bck.3 uc010ump.2) ENST00000560715
    ENST00000346495 ENST00000424443 ENST00000561277 ENST00000559494 ENST00000558745
    ENST00000558394 ENST00000560514 ENST00000559373
    miRNA
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    Block miRNA regulation of human, mouse, rat TSPAN3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSPAN3 (see all 65):
    hsa-miR-21* hsa-miR-323-3p hsa-miR-142-5p hsa-miR-136 hsa-miR-607 hsa-miR-1197 hsa-miR-1914* hsa-miR-199a-3p
    SwitchGear 3'UTR luciferase reporter plasmidTSPAN3 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: TSPAN3 (NM_005981)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPAN3
    Primer
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    OriGene qPCR primer pairs and template standards for TSPAN3
    OriGene qSTAR qPCR primer pairs in human, mouse for TSPAN3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSPAN3
      QuantiTect SYBR Green Assays in human, mouse, rat TSPAN3
      QuantiFast Probe-based Assays in human, mouse, rat TSPAN3

    Selected AceView cDNA sequences (see all 673):

    BP362892 AI026978 CN481853 BU687253 AA046969 BM556159 BQ891890 BQ679208 
    BC009248 CR609168 AW131508 CR604332 BM903880 BM704017 AW128929 BX355988 
    CD243225 AA366555 BQ424298 CR625746 CR598055 CA396172 BP373071 BU183577 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TSPAN3 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8
    SP1:                                -                                             
    SP2:                                -     -     -                                 
    SP3:                    -           -                                             
    SP4:                                                                              
    SP5:                                -     -                                       


    ECgene alternative splicing isoforms for TSPAN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TSPAN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGACTAGCA
    TSPAN3 Expression
    About this image


    TSPAN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 20) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Endochondral Facial Bones
     
     Blood (Hematopoietic System)
             Mature B-Cells Peripheral Blood
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
    TSPAN3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TSPAN3 Protein Expression
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TSPAN3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tspan31 , 5 tetraspanin 31, 5 90.91(n)1
    97.23(a)1
      9 (30.13 cM)5
    564341  NM_019793.31  NP_062767.31 
     561358855 
    chicken
    (Gallus gallus)
    Aves TSPAN31 tetraspanin 3 82.06(n)
    89.69(a)
      415348  NM_001257258.1  NP_001244187.1 
    lizard
    (Anolis carolinensis)
    Reptilia TSPAN36
    tetraspanin 3
    92(a)
    1 ↔ 1
    GL343374.1(913524-928765)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.237732 Xenopus laevis transcribed sequence with moderate similarity more 79.25(n)    BU914676.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tspan3a1 tetraspanin 3a 76.42(n)
    87.35(a)
      565579  NM_001025538.2  NP_001020709.1 


    ENSEMBL Gene Tree for TSPAN3 (if available)
    TreeFam Gene Tree for TSPAN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TSPAN3 gene
    CD1512  TSPAN52  TSPAN102  TSPAN172  TSPAN332  TSPAN62  CD632  TSPAN152  
    TSPAN72  TSPAN112  TSPAN142  ENSG000002503492  
    12 SIMAP similar genes for TSPAN3 using alignment to 4 protein entries:     TSN3_HUMAN (see all proteins):
    CD151    TSPAN11    CD63    TSPAN16    TM4SF2    TSPAN9
    TSPAN1    TSPAN6    TSPAN8    TSPAN7    TSPAN4    CD53

    Find genes that share paralogs with TSPAN3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TSPAN3 (see all 498)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs116366481,2
    C,F,H--77335891(+) gaaatC/Tgcaga 3 -- ds500120Minor allele frequency- T:0.36NS EA NA WA 2346
    rs116366131,2
    C,F,A,H--77335902(+) caaacA/Gcagat 3 -- ds500121Minor allele frequency- G:0.49NS EA NA WA CSA 2347
    rs1432954521,2
    --77336078(+) GGACAC/TGATGC 3 -- ds50010--------
    rs1180128261,2
    C,F--77336133(+) TGGACG/AGAATT 3 -- ds50011Minor allele frequency- A:0.02EA 120
    rs1816234281,2
    --77336222(+) GACAGA/GTGTGG 3 -- ds50010--------
    rs1165843231,2
    C,F--77336268(+) GTTGGC/TGCAAG 3 -- ds50011Minor allele frequency- T:0.04WA 118
    rs1862141491,2
    --77336414(+) GAAATA/CATTTC 3 -- ut310--------
    rs1140710591,2
    C,F--77336664(+) GCACTG/AGGTAA 3 -- ut311Minor allele frequency- A:0.03WA 118
    rs1915062121,2
    --77336795(+) TTTCCA/GGGACA 3 -- ut310--------
    rs1145767971,2
    C,F--77336949(+) GAGGCT/CGCTCT 3 -- ut311Minor allele frequency- C:0.01WA 118

    HapMap Linkage Disequilibrium report for TSPAN3 (77336359 - 77376326 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for TSPAN3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2749898CNV Deletion23290073
    nsv509576CNV Insertion20534489
    nsv1622CNV Insertion18451855
    nsv904414CNV Loss21882294
    nsv511547CNV Loss21212237
    nsv833058CNV Loss17160897
    nsv517068CNV Gain+Loss19592680
    dgv757e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TSPAN3
    DNA2.0 Custom Variant and Variant Library Synthesis for TSPAN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613134    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for TSPAN3:
    Echinococcosis

    Find genes that share disorders with TSPAN3           About GenesLikeMe


    Export disorders for TSPAN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TSPAN3 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with TSPAN3)
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    1. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Sequences and expression of six new members of the tetraspanin/TM4SF family. (PubMed id 9714763)1, 2 Todd S.C.... Levy S. (Biochim. Biophys. Acta 1998)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    9. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10099 HGNC: 17752 AceView: TM4SF8 Ensembl:ENSG00000140391 euGenes: HUgn10099
    ECgene: TSPAN3 H-InvDB: TSPAN3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TSPAN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TSPAN3 gene:
    Search GeneIP for patents involving TSPAN3

    GeneCards and IP:
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