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Aliases for TSPAN19 Gene

Aliases for TSPAN19 Gene

  • Tetraspanin 19 2 3 5
  • Tspan-19 3 4

External Ids for TSPAN19 Gene

Previous GeneCards Identifiers for TSPAN19 Gene

  • GC12M083911
  • GC12M085408
  • GC12M082465

Summaries for TSPAN19 Gene

GeneCards Summary for TSPAN19 Gene

TSPAN19 (Tetraspanin 19) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSPAN19 Gene

Genomics for TSPAN19 Gene

Regulatory Elements for TSPAN19 Gene

Promoters for TSPAN19 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TSPAN19 on UCSC Golden Path with GeneCards custom track

Genomic Location for TSPAN19 Gene

85,014,311 bp from pter
85,036,278 bp from pter
21,968 bases
Minus strand

Genomic View for TSPAN19 Gene

Genes around TSPAN19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TSPAN19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TSPAN19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSPAN19 Gene

Proteins for TSPAN19 Gene

  • Protein details for TSPAN19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative tetraspanin-19
    Protein Accession:

    Protein attributes for TSPAN19 Gene

    248 amino acids
    Molecular mass:
    28460 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TSPAN19 Gene

Proteomics data for TSPAN19 Gene at MOPED

Post-translational modifications for TSPAN19 Gene

  • Glycosylation at Asn 5 and Asn 158
  • Modification sites at PhosphoSitePlus

Other Protein References for TSPAN19 Gene

No data available for DME Specific Peptides for TSPAN19 Gene

Domains & Families for TSPAN19 Gene

Gene Families for TSPAN19 Gene

Protein Domains for TSPAN19 Gene

Suggested Antigen Peptide Sequences for TSPAN19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the tetraspanin (TM4SF) family.
  • Belongs to the tetraspanin (TM4SF) family.
genes like me logo Genes that share domains with TSPAN19: view

Function for TSPAN19 Gene

Animal Model Products

CRISPR Products

miRNA for TSPAN19 Gene

miRTarBase miRNAs that target TSPAN19

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TSPAN19 Gene

Localization for TSPAN19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TSPAN19 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TSPAN19 Gene COMPARTMENTS Subcellular localization image for TSPAN19 gene
Compartment Confidence
plasma membrane 4
extracellular 1

Gene Ontology (GO) - Cellular Components for TSPAN19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TSPAN19: view

Pathways & Interactions for TSPAN19 Gene

SuperPathways for TSPAN19 Gene

No Data Available

Interacting Proteins for TSPAN19 Gene

Gene Ontology (GO) - Biological Process for TSPAN19 Gene


No data available for Pathways by source and SIGNOR curated interactions for TSPAN19 Gene

Drugs & Compounds for TSPAN19 Gene

No Compound Related Data Available

Transcripts for TSPAN19 Gene

Unigene Clusters for TSPAN19 Gene

Tetraspanin 19:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TSPAN19 Gene

No ASD Table

Relevant External Links for TSPAN19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TSPAN19 Gene

mRNA expression in normal human tissues for TSPAN19 Gene

mRNA differential expression in normal tissues according to GTEx for TSPAN19 Gene

This gene is overexpressed in Pituitary (x6.4), Testis (x5.8), Brain - Hypothalamus (x5.1), and Lung (x4.4).

SOURCE GeneReport for Unigene cluster for TSPAN19 Gene Hs.156962

genes like me logo Genes that share expression patterns with TSPAN19: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TSPAN19 Gene

Orthologs for TSPAN19 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TSPAN19 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TSPAN19 35
  • 84.75 (n)
  • 74.49 (a)
TSPAN19 36
  • 74 (a)
(Canis familiaris)
Mammalia TSPAN19 35
  • 86.29 (n)
  • 77.42 (a)
TSPAN19 36
  • 78 (a)
(Pan troglodytes)
Mammalia TSPAN19 35
  • 99.46 (n)
  • 98.79 (a)
TSPAN19 36
  • 99 (a)
(Gallus gallus)
Aves TSPAN19 35
  • 60.62 (n)
  • 43.88 (a)
TSPAN19 36
  • 40 (a)
(Danio rerio)
Actinopterygii LOC101884436 35
  • 45.76 (n)
  • 27.54 (a)
TSPAN19 36
  • 17 (a)
Species with no ortholog for TSPAN19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TSPAN19 Gene

Gene Tree for TSPAN19 (if available)
Gene Tree for TSPAN19 (if available)

Paralogs for TSPAN19 Gene

(3) SIMAP similar genes for TSPAN19 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with TSPAN19: view

No data available for Paralogs for TSPAN19 Gene

Variants for TSPAN19 Gene

Sequence variations from dbSNP and Humsavar for TSPAN19 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs982602 -- 85,032,528(-) TACCA(C/T)AAACA intron-variant
rs1525548 -- 85,021,583(+) CTTTC(C/T)TATGT intron-variant
rs1404868 -- 85,028,812(-) TAGAG(A/C)ATATT intron-variant
rs1404871 -- 85,016,838(+) TTTTT(A/T)AAAAA intron-variant
rs1838671 -- 85,025,278(-) GGCAC(C/T)GGTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TSPAN19 Gene

Variant ID Type Subtype PubMed ID
nsv899377 CNV Loss 21882294
nsv510605 CNV Loss 20534489
nsv899387 CNV Loss 21882294
nsv899388 CNV Loss 21882294

Variation tolerance for TSPAN19 Gene

Residual Variation Intolerance Score: 77% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.97; 49.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TSPAN19 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TSPAN19 Gene

Disorders for TSPAN19 Gene

Relevant External Links for TSPAN19

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TSPAN19 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TSPAN19 Gene

Publications for TSPAN19 Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4 67
  2. Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains. (PMID: 18795891) Protty M.B. … Tomlinson M.G. (Biochem. J. 2009) 23
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for TSPAN19 Gene

Sources for TSPAN19 Gene

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