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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TSPAN18 Gene

protein-coding   GIFtS: 45
GCID: GC11P044838

Tetraspanin 18

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tetraspanin 181 2
TSPAN2
tetraspanin-182
tspan-182
Tspan-183

External Ids:    HGNC: 206601   Entrez Gene: 901392   Ensembl: ENSG000001575707   UniProtKB: Q96SJ83   

Export aliases for TSPAN18 gene to outside databases

Previous GC identifer: GC11P044496


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TSPAN18 Gene: 
TSPAN18 (tetraspanin 18) is a protein-coding gene. Diseases associated with TSPAN18 include schizophrenia. An important paralog of this gene is CD151.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TSPAN18 gene promoter:
         Egr-3   NF-1   AML1a   Egr-1   POU3F2   Egr-4   Chx10   LyF-1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTSPAN18 promoter sequence
   Search SABiosciences Chromatin IP Primers for TSPAN18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSPAN18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p11.2   Ensembl cytogenetic band:  11p11.2   HGNC cytogenetic band: 11p11.2

TSPAN18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSPAN18 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P044838:  view genomic region     (about GC identifiers)

Start:
44,748,015 bp from pter      End:
44,953,978 bp from pter
Size:
205,964 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TSN18_HUMAN, Q96SJ8 (See protein sequence)
Recommended Name: Tetraspanin-18  
Size: 248 amino acids; 27710 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=BAC11690.1; Type=Erroneous initiation;
Secondary accessions: Q6UY44 Q8NBI9

Explore the universe of human proteins at neXtProt for TSPAN18: NX_Q96SJ8

TSPAN18 Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --

REFSEQ proteins: NP_570139.3  
ENSEMBL proteins: 
 ENSP00000433592   ENSP00000434625   ENSP00000433362   ENSP00000429993   ENSP00000427942  
 ENSP00000430343   ENSP00000429020   ENSP00000339820  

Human Recombinant Protein Products for TSPAN18: 
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OriGene Protein Over-expression Lysate for TSPAN18
OriGene Custom MassSpec 
OriGene Custom Protein Services for TSPAN18
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Novus Biologicals TSPAN18 Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for TSPAN18 

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral to membrane IEA--

TSPAN18 for ontologies           About GeneDecksing



TSPAN18 Antibody Products: 
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LSBio Antibodies in human, mouse, rat for TSPAN18 

Assay Products for TSPAN18: 
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Cloud-Clone Corp. ELISAs for TSPAN18 
Cloud-Clone Corp. CLIAs for TSPAN18


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
TSPAN: Tetraspanins

4 InterPro protein domains:
 IPR018499 Tetraspanin/Peripherin
 IPR018503 Tetraspanin_CS
 IPR000301 Tetraspanin
 IPR008952 Tetraspanin_EC2

Graphical View of Domain Structure for InterPro Entry Q96SJ8

ProtoNet protein and cluster: Q96SJ8

1 Blocks protein domain: IPB000301 Transmembrane four family signature

UniProtKB/Swiss-Prot: TSN18_HUMAN, Q96SJ8
Similarity: Belongs to the tetraspanin (TM4SF) family


TSPAN18 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Phenotypes:
     1 MGI phenotypic allele for Tspan18 (no phenotypes)

TSPAN18 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Tspan18tm1Lex for TSPAN18

   inGenious Targeting Laboratory - Custom generated mouse model solutions for TSPAN18 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TSPAN18

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TSPAN18 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TSPAN18 

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TSPAN18
8/57 QIAGEN miScript miRNA Assays for microRNAs that regulate TSPAN18 (see all 57):
hsa-miR-579 hsa-let-7d hsa-miR-330-5p hsa-miR-765 hsa-miR-301a hsa-miR-449a hsa-let-7g hsa-miR-9
SwitchGear 3'UTR luciferase reporter plasmidTSPAN18 3' UTR sequence
Inhib. RNA
Products:
    
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OriGene RNAi products in human, mouse, rat for TSPAN18
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Gene Editing
Products:
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Clone
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OriGene clones in human, mouse for TSPAN18 (see all 11)
OriGene ORF clones in mouse, rat for TSPAN18
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GenScript: all cDNA clones in your preferred vector: TSPAN18 (NM_130783)
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSPAN18
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPAN18
Sirion Biotech Customized lentivirus for stable overexpression of TSPAN18 
                     Customized lentivirus expression plasmids for stable overexpression of TSPAN18 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for TSPAN18
LifeMap BioReagents: cell lines associated with TSPAN18: PureStem MEL2, NCr-fac Progenitor,
PureStem SK11, NCr-fac & Meso-prx Progenitor
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPAN18


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TSPAN18

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TSPAN18 (TSN18)

Search CenterWatch for drugs/clinical trials and news about TSPAN18 / TSN18

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TSPAN18 gene (2 alternative transcripts): 
NM_001031730.1  NM_130783.4  

Unigene Cluster for TSPAN18:

Tetraspanin 18
Hs.385634  [show with all ESTs]
Unigene Representative Sequence: NM_130783
13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000533786 ENST00000533202 ENST00000533080 ENST00000520358 ENST00000520999
ENST00000520837 ENST00000518429(uc001myg.3) ENST00000519051 ENST00000520245
ENST00000517621 ENST00000521990 ENST00000520278 ENST00000340160(uc001mye.4)

miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TSPAN18
8/57 QIAGEN miScript miRNA Assays for microRNAs that regulate TSPAN18 (see all 57):
hsa-miR-579 hsa-let-7d hsa-miR-330-5p hsa-miR-765 hsa-miR-301a hsa-miR-449a hsa-let-7g hsa-miR-9
SwitchGear 3'UTR luciferase reporter plasmidTSPAN18 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for TSPAN18
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TSPAN18
Clone
Products:
     
OriGene clones in human, mouse for TSPAN18 (see all 11)
OriGene ORF clones in mouse, rat for TSPAN18
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: TSPAN18 (NM_130783)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSPAN18
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSPAN18
Sirion Biotech Customized lentivirus for stable overexpression of TSPAN18 
                     Customized lentivirus expression plasmids for stable overexpression of TSPAN18 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for TSPAN18
OriGene qSTAR qPCR primer pairs in human, mouse for TSPAN18
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TSPAN18
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSPAN18
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSPAN18

Additional mRNA sequence: 

AK027515.1 AK027715.1 AK075547.1 AY358087.1 BC019342.2 

20 DOTS entries:

DT.95167083  DT.100757525  DT.91667654  DT.100801564  DT.120709731  DT.120709677  DT.120709695  DT.120709733 
DT.120709739  DT.447356  DT.91753527  DT.95167093  DT.100642756  DT.120709743  DT.91989708  DT.95167088 
DT.100649893  DT.120709774  DT.120709777  DT.91917603 

24/170 AceView cDNA sequences (see all 170):

BM672270 BQ006406 BF222454 AI343458 BP334243 BE296419 BM700925 AI146822 
CR597335 BF438041 AA227614 AA326605 BE326377 T34493 BF222231 BE269763 
BX416503 AI632087 AI160268 AI215915 BM726565 BF437556 Z42871 AW205519 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TSPAN18 expression in normal human tissues (normalized intensities)      TSPAN18 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGTCATATGT
TSPAN18 Expression
About this image


TSPAN18 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/22 selected tissues (see all 22) fully expand
 
 Endothelium (Cardiovascular System)    fully expand to see all 19 entries
         PureStem endothelial progenitor 30-SM2-1
         Human Cardiac Microvascular Endothelial Cells (HCMEC)   
 
 Blood (Hematopoietic System)    fully expand to see all 3 entries
         PureStem endothelial Progenitor 30-SM2-3
         platelets   
 
 Bone (Muscoskeletal System)    fully expand to see all 3 entries
         HyStem+TGFbeta3+GDF5-induced SK11 cells
         Normal Human osteoblasts (NHOST)   
 
 Brain (Nervous System)    fully expand to see all 3 entries
         Human Astrocytes   
 
 Heart (Cardiovascular System)    fully expand to see all 3 entries
         Human Cardiac Myocytes-adult (HCM-a)   

Genevestigator expression for TSPAN18

SOURCE GeneReport for Unigene cluster: Hs.385634
    SABiosciences Custom PCR Arrays for TSPAN18
Primer
Products:
OriGene qPCR primer pairs and template standards for TSPAN18
OriGene qSTAR qPCR primer pairs in human, mouse for TSPAN18
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QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSPAN18
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSPAN18
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSPAN18

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TSPAN18 gene from 6/14 species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tspan181 , 5 tetraspanin 181, 5 87.1(n)1
90.73(a)1
  2 (51.37 cM)5
2415561  NM_183180.21  NP_899003.11 
 932017605 
chicken
(Gallus gallus)
Aves TSPAN181 tetraspanin 18 76.25(n)
81.38(a)
  395586  NM_204801.1  NP_990132.1 
lizard
(Anolis carolinensis)
Reptilia TSPAN186
--
Uncharacterized protein
83(a)
42(a)
1 ↔ 1
possible ortholog
1(46505508-46533679)
4(133566172-133574118)
African clawed frog
(Xenopus laevis)
Amphibia LOC3985862 similar to tetraspanin similiar to uroplakin 1 75.14(n)    BC049346.1 
zebrafish
(Danio rerio)
Actinopterygii tspan18b1 tetraspanin 18b 73.44(n)
72.76(a)
  436712  NM_001002439.1  NP_001002439.1 
fruit fly
(Drosophila melanogaster)
Insecta Tsp74F6
Tetraspanin 74F
28(a)
1 → many
3L(17884920-17888962)


ENSEMBL Gene Tree for TSPAN18 (if available)
TreeFam Gene Tree for TSPAN18 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for TSPAN18 gene
CD1512  TSPAN12  TSPAN62  CD372  TSPAN32  TSPAN92  CD632  TSPAN192  
CD532  CD822  TSPAN72  TSPAN112  TSPAN42  ENSG000002503492  
18/21 SIMAP similar genes for TSPAN18 using alignment to 8 protein entries:     TSN18_HUMAN (see all proteins) (see all similar genes):
CD82    BTCC-1    CD53    CD151    CD9    TSPAN5
TSPAN4    TSPAN1    TSPAN11    TSPAN16    CD37    TSPAN8
CD63    TSPAN6    TSPAN17    TSPAN9    TM4SF2    TSPAN7

TSPAN18 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/3551 SNPs in TSPAN18 are shown (see all 3551)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1144139771,2
F--44783992(+) ATACAC/TGTATT 1 -- us2k11Minor allele frequency- T:0.02WA 118
rs1407073421,2
C--44784044(+) GTTTGC/TAGTGG 1 -- us2k10--------
rs1839789771,2
C--44784153(+) TACCTA/CTATAT 1 -- us2k10--------
rs1434854281,2
C--44784166(+) ACATA-/TGTGTGT 1 -- us2k10--------
rs1883123081,2
--44784254(+) GGTTCA/GTGATG 1 -- us2k10--------
rs1459091001,2
C--44784319(+) CTAAAC/TAAAAT 1 -- us2k10--------
rs1807798371,2
--44784345(+) AGCCAA/GTCCCT 1 -- us2k10--------
rs1863796941,2
C--44784432(+) GACCTC/TGAACT 1 -- us2k10--------
rs1382105891,2
--44784477(+) GGCGAA/GCGTGA 1 -- us2k10--------
rs71048961,2
C,F,A,H--44784540(+) GCACCA/GGGCTT 1 -- us2k126Minor allele frequency- G:0.47EA NA NS WA CSA 2567

HapMap Linkage Disequilibrium report for TSPAN18 (44748015 - 44953978 bp)

Structural Variations
     Database of Genomic Variants (DGV) 5 variations for TSPAN18:    About this table     
Variant IDTypeSubtypePubMed ID
esv2744420CNV Deletion23290073
nsv510252CNV Loss20534489
nsv832140CNV Loss17160897
nsv304CNV Loss18451855
esv28960CNV Gain19812545

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing TSPAN18
DNA2.0 Custom Variant and Variant Library Synthesis for TSPAN18

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
2 diseases for TSPAN18:    About MalaCards
schizophrenia    


TSPAN18 for disorders           About GeneDecksing

Genetic Association Database (GAD): TSPAN18
Human Genome Epidemiology (HuGE) Navigator: TSPAN18 (2 documents)

Export disorders for TSPAN18 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for TSPAN18 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with TSPAN18)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Genome-wide association study identifies a susceptibi lity locus for schizophrenia in Han Chinese at 11p11.2. (PubMed id 22037552)1, 4 Yue W.H....Zhang D. (2011)
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
  3. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (2009)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
  6. Specific tetraspanin functions. (PubMed id 11756464)1, 3 Hemler M.E. (2001)
  7. Replication study confirms link between TSPAN18 mutati on and schizophrenia in Han Chinese. (PubMed id 23505562)1 Yuan J....Shugart Y.Y. (2013)
  8. The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)1 Lin C.W....Jan M.S. (2012)
  9. Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins. (PubMed id 17192395)1 Macaulay I.C....Ouwehand W.H. (2007)
  10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 90139 HGNC: 20660 AceView: LOC90139 Ensembl:ENSG00000157570 euGenes: HUgn90139
ECgene: TSPAN18 H-InvDB: TSPAN18

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for TSPAN18 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for TSPAN18 gene:
Search GeneIP for patents involving TSPAN18

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Proteins for TSPAN18
 Antibodies for TSPAN18
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Customized transgenic rodents for:
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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transforming growth factor, beta 1
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