Aliases for TSPAN15 Gene
External Ids for TSPAN15 Gene
Previous HGNC Symbols for TSPAN15 Gene
Previous GeneCards Identifiers for TSPAN15 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for TSPAN15 Gene
TSPAN15 (Tetraspanin 15) is a Protein Coding gene. GO annotations related to this gene include enzyme binding. An important paralog of this gene is TSPAN33.
UniProtKB/Swiss-Prot for TSPAN15 Gene
Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.