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Aliases for TSNAXIP1 Gene

Aliases for TSNAXIP1 Gene

  • Translin-Associated Factor X Interacting Protein 1 2 3
  • Trax-Interacting Protein 1 3 4
  • TXI1 3 4
  • Translin-Associated Factor X-Interacting Protein 1 3

External Ids for TSNAXIP1 Gene

Previous GeneCards Identifiers for TSNAXIP1 Gene

  • GC16P058535
  • GC16P068218
  • GC16P067577
  • GC16P067617
  • GC16P066398
  • GC16P067840
  • GC16P053713

Summaries for TSNAXIP1 Gene

GeneCards Summary for TSNAXIP1 Gene

TSNAXIP1 (Translin-Associated Factor X Interacting Protein 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TSNAXIP1 Gene

  • Possible role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSNAXIP1 Gene

Genomics for TSNAXIP1 Gene

Regulatory Elements for TSNAXIP1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TSNAXIP1 Gene

67,806,573 bp from pter
67,832,148 bp from pter
25,576 bases
Plus strand

Genomic View for TSNAXIP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TSNAXIP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSNAXIP1 Gene

Proteins for TSNAXIP1 Gene

  • Protein details for TSNAXIP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Translin-associated factor X-interacting protein 1
    Protein Accession:
    Secondary Accessions:
    • Q9P105

    Protein attributes for TSNAXIP1 Gene

    658 amino acids
    Molecular mass:
    76773 Da
    Quaternary structure:
    • Interacts with TSNAX.

    Alternative splice isoforms for TSNAXIP1 Gene


neXtProt entry for TSNAXIP1 Gene

Proteomics data for TSNAXIP1 Gene at MOPED

Post-translational modifications for TSNAXIP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for TSNAXIP1 Gene

Domains for TSNAXIP1 Gene

Protein Domains for TSNAXIP1 Gene


Suggested Antigen Peptide Sequences for TSNAXIP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TSNAXIP1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TSNAXIP1 Gene

Function for TSNAXIP1 Gene

Molecular function for TSNAXIP1 Gene

UniProtKB/Swiss-Prot Function:
Possible role in spermatogenesis.

Gene Ontology (GO) - Molecular Function for TSNAXIP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TSNAXIP1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TSNAXIP1 Gene

Localization for TSNAXIP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TSNAXIP1 Gene

Cytoplasm, perinuclear region.

Subcellular locations from

Jensen Localization Image for TSNAXIP1 Gene COMPARTMENTS Subcellular localization image for TSNAXIP1 gene
Compartment Confidence
cytosol 2
extracellular 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TSNAXIP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005737 cytoplasm --
GO:0048471 perinuclear region of cytoplasm IEA --
genes like me logo Genes that share ontologies with TSNAXIP1: view

Pathways for TSNAXIP1 Gene

SuperPathways for TSNAXIP1 Gene

No Data Available

Interacting Proteins for TSNAXIP1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000373485 Q2TAA8-TXIP1_HUMAN for TSNAXIP1 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for TSNAXIP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007275 multicellular organismal development IEA --
GO:0007283 spermatogenesis IEA --
GO:0008150 biological_process ND --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with TSNAXIP1: view

No data available for Pathways by source for TSNAXIP1 Gene

Transcripts for TSNAXIP1 Gene

Unigene Clusters for TSNAXIP1 Gene

Translin-associated factor X interacting protein 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TSNAXIP1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TSNAXIP1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h · 1i ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13 ^ 14 ^
SP2: - - -
SP3: - - - - -
SP4: - - - - - - -
SP5: - -
SP6: - -
SP7: -
SP8: - - - - - - -
SP9: - - - -

ExUns: 15 ^ 16

Relevant External Links for TSNAXIP1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TSNAXIP1 Gene

mRNA expression in normal human tissues for TSNAXIP1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TSNAXIP1 Gene

This gene is overexpressed in Testis (8.6) and Pituitary (5.3).

Protein differential expression in normal tissues for TSNAXIP1 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (42.0), Cervix (19.5), and Plasma (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TSNAXIP1 Gene

SOURCE GeneReport for Unigene cluster for TSNAXIP1 Gene Hs.632212

genes like me logo Genes that share expressions with TSNAXIP1: view

Expression partners for TSNAXIP1 Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TSNAXIP1 Gene

Orthologs for TSNAXIP1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TSNAXIP1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TSNAXIP1 35
  • 86.26 (n)
  • 82 (a)
  • 78 (a)
(Canis familiaris)
Mammalia TSNAXIP1 35
  • 87.03 (n)
  • 84.97 (a)
  • 80 (a)
(Mus musculus)
Mammalia Tsnaxip1 35
  • 79.78 (n)
  • 75.71 (a)
Tsnaxip1 16
Tsnaxip1 36
  • 72 (a)
(Pan troglodytes)
Mammalia TSNAXIP1 35
  • 99.16 (n)
  • 98.6 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Tsnaxip1 35
  • 80.52 (n)
  • 77.02 (a)
(Monodelphis domestica)
Mammalia TSNAXIP1 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 43 (a)
-- 36
  • 57 (a)
(Gallus gallus)
Aves TSNAXIP1 35
  • 59.71 (n)
  • 50.92 (a)
  • 46 (a)
(Anolis carolinensis)
Reptilia TSNAXIP1 36
  • 52 (a)
(Danio rerio)
Actinopterygii tsnaxip1 35
  • 50.42 (n)
  • 37.39 (a)
tsnaxip1 36
  • 33 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 28 (a)
Species with no ortholog for TSNAXIP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TSNAXIP1 Gene

Gene Tree for TSNAXIP1 (if available)
Gene Tree for TSNAXIP1 (if available)

Paralogs for TSNAXIP1 Gene

No data available for Paralogs for TSNAXIP1 Gene

Variants for TSNAXIP1 Gene

Sequence variations from dbSNP and Humsavar for TSNAXIP1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs1109273 -- 67,822,294(+) aaaaa(A/G)aaaga intron-variant
rs2008173 -- 67,822,337(+) GATCC(A/G)AAAGT intron-variant
rs2292316 -- 67,827,231(+) TGGCC(C/G)TCATG intron-variant
rs3743731 -- 67,814,259(+) CCACT(C/G)TGGAC intron-variant
rs3743732 -- 67,826,088(+) GCAGC(C/T)GGCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TSNAXIP1 Gene

Variant ID Type Subtype PubMed ID
nsv524363 CNV Loss 19592680
nsv522852 CNV Gain 19592680
dgv502e199 CNV Deletion 23128226

Relevant External Links for TSNAXIP1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TSNAXIP1 Gene

Disorders for TSNAXIP1 Gene

No disorders were found for TSNAXIP1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TSNAXIP1 Gene

Publications for TSNAXIP1 Gene

  1. Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X. (PMID: 12036294) Bray J.D. … Hecht N.B. (Genomics 2002) 2 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Lack of association between translin-associated factor X gene (TSNAX) and methamphetamine dependence in the Japanese population. (PMID: 21683752) Kishi T. … Iwata N. (Prog. Neuropsychopharmacol. Biol. Psychiatry 2011) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for TSNAXIP1 Gene

Sources for TSNAXIP1 Gene

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