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TSKU Gene

protein-coding   GIFtS: 52
GCID: GC11P076494

Tsukushi, Small Leucine Rich Proteoglycan

(Previous names: leucine rich repeat containing 54, tsukushin, tsukushi small...)
(Previous symbol: LRRC54)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tsukushi, Small Leucine Rich Proteoglycan1 2     Leucine-Rich Repeat-Containing Protein 542 3
LRRC541 2 3     E2-Induced Gene 4 Protein2 3
E2IG42 3 5     Tsukushi Small Leucine Rich Proteoglycan Homolog (Xenopus Laevis)1
TSK2 3 5     Tsukushi Homolog2
Leucine Rich Repeat Containing 541 2     Tsukushi Small Leucine Rich Proteoglycan Homolog2
tsukushin1 2     Tsukushi3

External Ids:    HGNC: 288501   Entrez Gene: 259872   Ensembl: ENSG000001827047   OMIM: 6080155   UniProtKB: Q8WUA83   

Export aliases for TSKU gene to outside databases

Previous GC identifers: GC11P076171 GC11P072791


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TSKU Gene:
TSKU (tsukushi, small leucine rich proteoglycan) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_167190.2  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TSKU gene promoter:
         COUP-TF1   AP-1   COUP   Nkx5-1   Evi-1   Egr-4   GATA-1   GATA-2   AREB6   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTSKU promoter sequence
   Search Chromatin IP Primers for TSKU

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSKU


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.5   Ensembl cytogenetic band:  11q13.5   HGNC cytogenetic band: 11q13.5

TSKU Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSKU gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P076494:  view genomic region     (about GC identifiers)

Start:
76,493,295 bp from pter      End:
76,509,198 bp from pter
Size:
15,904 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TSK_HUMAN, Q8WUA8 (See protein sequence)
Recommended Name: Tsukushin precursor  
Size: 353 amino acids; 37807 Da
Secondary accessions: B3KQT7 Q6UXK1 Q9UG10 Q9UJX9

Explore the universe of human proteins at neXtProt for TSKU: NX_Q8WUA8

Explore proteomics data for TSKU at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn74, Asn137, Thr152, Thr153, Ser248
  • Modification sites at PhosphoSitePlus

  • See TSKU Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001245139.1  NP_056331.2  

    ENSEMBL proteins: 
     ENSP00000435133   ENSP00000332668   ENSP00000434873   ENSP00000434847  

    TSKU Human Recombinant Protein Products:

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    Novus Biologicals TSKU Proteins
    Novus Biologicals TSKU Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for TSKU 

     
    antibodies-online proteins for TSKU (3 products) 

     
    antibodies-online peptides for TSKU

    TSKU Antibody Products:

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    antibodies-online antibodies for TSKU (17 products) 

    TSKU Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
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    Search eBioscience for ELISAs for TSKU 
    antibodies-online kits for TSKU (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR001611 Leu-rich_rpt
     IPR003591 Leu-rich_rpt_typical-subtyp
     IPR000372 LRR-contain_N

    Graphical View of Domain Structure for InterPro Entry Q8WUA8

    ProtoNet protein and cluster: Q8WUA8

    1 Blocks protein domain: IPB000372 Cysteine-rich flanking region

    UniProtKB/Swiss-Prot: TSK_HUMAN, Q8WUA8
    Similarity: Contains 10 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRNT domain


    Find genes that share domains with TSKU           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TSK_HUMAN, Q8WUA8
    Induction: By 17-beta-estradiol

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with TSKU           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TSKU:
     Decreased homologous recombina 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Tsku):
     nervous system 

    Find genes that share phenotypes with TSKU           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TSKU

    miRNA
    Products:
        
    miRTarBase miRNAs that target TSKU:
    hsa-mir-769-5p (MIRT039200), hsa-mir-124-3p (MIRT004908), hsa-mir-196a-5p (MIRT048164), hsa-mir-26b-5p (MIRT029592), hsa-mir-7-5p (MIRT025821)

    Block miRNA regulation of human, mouse, rat TSKU using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSKU (see all 20):
    hsa-miR-1271 hsa-miR-29b-1* hsa-miR-105 hsa-miR-124 hsa-miR-4274 hsa-miR-7-1* hsa-miR-3662 hsa-miR-506
    SwitchGear 3'UTR luciferase reporter plasmidTSKU 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TSKU

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    Sino Biological Human cDNA Clone for TSKU
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSKU

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSKU


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TSK_HUMAN, Q8WUA8: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    cytosol2
    nucleus2
    plasma membrane2
    endoplasmic reticulum1
    lysosome1
    vacuole1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--

    Find genes that share ontologies with TSKU           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TSKU
    Interactions:

        GeneGlobe Interaction Network for TSKU

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for TSKU (Q8WUA82, 3 ENSP000003326684) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SKILP127572, 3MINT-61667 I2D: score=3 
    CAB39ENSP000002584184STRING: ENSP00000258418
    CAB39LENSP000002616694STRING: ENSP00000261669
    MFAP1ENSP000002678124STRING: ENSP00000267812
    --ENSP000002626244STRING: ENSP00000262624
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010468regulation of gene expression IEA--
    GO:0021540corpus callosum morphogenesis IEA--
    GO:0021670lateral ventricle development IEA--
    GO:0021960anterior commissure morphogenesis IEA--
    GO:0030178negative regulation of Wnt signaling pathway IEA--

    Find genes that share ontologies with TSKU           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TSKU (TSK)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TSKU gene (2 alternative transcripts): 
    NM_001258210.1  NM_015516.3  

    Unigene Cluster for TSKU:

    Tsukushi, small leucine rich proteoglycan
    Hs.8361  [show with all ESTs]
    Unigene Representative Sequence: AK126536
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000533752 ENST00000333090(uc001oxt.3) ENST00000525167 ENST00000527881

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TSKU using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSKU (see all 20):
    hsa-miR-1271 hsa-miR-29b-1* hsa-miR-105 hsa-miR-124 hsa-miR-4274 hsa-miR-7-1* hsa-miR-3662 hsa-miR-506
    SwitchGear 3'UTR luciferase reporter plasmidTSKU 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TSKU
    Predesigned siRNA for gene silencing in human, mouse, rat TSKU
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    OriGene ORF clones in mouse, rat for TSKU
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TSKU (NM_015516)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSKU
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSKU
    Primer
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    OriGene qPCR primer pairs and template standards for TSKU
    OriGene qSTAR qPCR primer pairs in human, mouse for TSKU
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSKU
      QuantiTect SYBR Green Assays in human, mouse, rat TSKU
      QuantiFast Probe-based Assays in human, mouse, rat TSKU

    Additional mRNA sequence: 

    AF191019.1 AK075476.1 AK091475.1 AK126536.1 AK313405.1 AL110276.1 AY358317.1 BC020975.1 
    BT007440.1 

    10 DOTS entries:

    DT.417669  DT.100777424  DT.100754481  DT.120701703  DT.91768837  DT.100777423  DT.91768832  DT.120701695 
    DT.120701697  DT.40215150 

    Selected AceView cDNA sequences (see all 258):

    AA651701 NM_015516 BM707831 AI826822 BE336901 BM704369 BX365318 BU846213 
    BG697318 AW183447 BU855121 BG327574 BC020975 AI074139 BX463614 CB051400 
    AL553726 BU539454 BM702062 BE786245 BM723751 BM679949 AI613032 BF725906 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TSKU expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCATCAGGG
    TSKU Expression
    About this image

    TSKU Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TSKU Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.8361
        Custom PCR Arrays for TSKU
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSKU

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TSKU gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tsku1 , 5 tsukushi1, 5 82.43(n)1
    85.39(a)1
      7 (53.66 cM)5
    2441521  NM_001168539.11  NP_001162011.11 
     983506685 
    chicken
    (Gallus gallus)
    Aves TSKU1 tsukushi small leucine rich proteoglycan homolog (Xenopus more 60.12(n)
    57.01(a)
      419088  NM_001005346.1  NP_001005346.1 
    lizard
    (Anolis carolinensis)
    Reptilia TSKU6
    tsukushi, small leucine rich proteoglycan
    53(a)
    1 ↔ 1
    AAWZ02036615(20249-21304)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tsku1 tsukushi, small leucine rich proteoglycan 58.95(n)
    50.45(a)
      496792  NM_001011330.1  NP_001011330.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd51d022 wufd51d02 79.24(n)   325958  BC047843.1 


    ENSEMBL Gene Tree for TSKU (if available)
    TreeFam Gene Tree for TSKU (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TSKU (see all 435)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1807416591,2
    --76491507(+) GTCCCC/TGACAT 1 -- us2k10--------
    rs1863066811,2
    --76491623(+) CCAGAC/GAGAGG 1 -- us2k10--------
    rs1891519791,2
    --76491642(+) GGGGCA/GAAGAC 1 -- us2k10--------
    rs1818737801,2
    --76491725(+) TTGGGA/TTGTGT 1 -- us2k10--------
    rs1860343671,2
    --76491828(+) TTGCCA/GTTGAA 1 -- us2k10--------
    rs1917643091,2
    --76491975(+) GAGGGG/TAGGTG 1 -- us2k10--------
    rs1442681851,2
    --76491987(+) GTAAAA/GTTCAT 1 -- us2k10--------
    rs1465869491,2
    --76492178(+) CACACA/CGTGCA 1 -- us2k10--------
    rs71074091,2
    C,F,A--76492195(+) GTTAGC/TTTCCC 1 -- us2k110Minor allele frequency- T:0.26NA WA CSA EA 372
    rs1144665691,2
    --76492216(+) GGCAGC/TTGGGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TSKU (76493295 - 76509198 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TSKU:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv897931CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TSKU
    DNA2.0 Custom Variant and Variant Library Synthesis for TSKU

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608015    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for TSKU:
    Fibromyalgia

    Find genes that share disorders with TSKU           About GenesLikeMe


    Export disorders for TSKU gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TSKU gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with TSKU)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Effects of estrogen on global gene expression: identification of novel targets of estrogen action. (PubMed id 11085516)1, 2, 3 Charpentier A.H.... Aldaz C.M. (Cancer Res. 2000)
    2. Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer. (PubMed id 22880013)1, 3 Henke A....Thomson A.A. (PLoS ONE 2012)
    3. Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human. (PubMed id 19710929)1, 3 Rakhshandehroo M....Kersten S. (PLoS ONE 2009)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    7. Tsukushi controls the hair cycle by regulating TGF-I^1 signaling. (PubMed id 22995554)1 Niimori D....Ohta K. (Dev. Biol. 2012)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. Functional proteomics mapping of a human signaling pathway. (PubMed id 15231748)1 Colland F....Gauthier J.M. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25987 HGNC: 28850 AceView: TSK Ensembl:ENSG00000182704 euGenes: HUgn25987
    ECgene: TSKU H-InvDB: TSKU

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TSKU Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TSKU gene:
    Search GeneIP for patents involving TSKU

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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