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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TSHZ1 Gene

protein-coding   GIFtS: 51
GCID: GC18P072922

Teashirt Zinc Finger Homeobox 1

(Previous names: serologically defined colon cancer antigen 33, teashirt...)
(Previous symbol: SDCCAG33)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Teashirt Zinc Finger Homeobox 11 2     Teashirt Family Zinc Finger 11
Serologically Defined Colon Cancer Antigen 331 2 3     Teashirt Zinc Finger 11
SDCCAG331 2 3     CAA2
Antigen NY-CO-332 3     NY-CO-332
TSH12 3     Teashirt Homolog 12

External Ids:    HGNC: 106691   Entrez Gene: 101942   Ensembl: ENSG000001799817   OMIM: 6144275   UniProtKB: Q6ZSZ63   

Export aliases for TSHZ1 gene to outside databases

Previous GC identifers: GC18P071051 GC18P069607


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TSHZ1 Gene:
This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression
libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be
involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with
congenital aural atresia syndrome. (provided by RefSeq, Jan 2012)

GeneCards Summary for TSHZ1 Gene: 
TSHZ1 (teashirt zinc finger homeobox 1) is a protein-coding gene. Diseases associated with TSHZ1 include congenital aural atresia, and microtia. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is TSHZ3.

UniProtKB/Swiss-Prot: TSH1_HUMAN, Q6ZSZ6
Function: Probable transcriptional regulator involved in developmental processes. May act as a transcriptional
repressor (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NT_025028.14  NC_018929.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TSHZ1 gene promoter:
         GR   Sox5   GATA-3   GR-beta   FOXD3   LCR-F1   GATA-2   GATA-1   GR-alpha   RSRFC4   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TSHZ1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSHZ1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q22.3   Ensembl cytogenetic band:  18q22.3   HGNC cytogenetic band: 18q22.3

TSHZ1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSHZ1 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P072922:  view genomic region     (about GC identifiers)

Start:
72,922,710 bp from pter      End:
73,001,905 bp from pter
Size:
79,196 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TSH1_HUMAN, Q6ZSZ6 (See protein sequence)
Recommended Name: Teashirt homolog 1  
Size: 1077 amino acids; 117916 Da
Subunit: Interacts (via homeobox domain) with APBB1 (via PID domain 1) (By similarity)
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAC18047.1; Type=Frameshift; Positions=304, 1048; Sequence=BAE06124.1; Type=Erroneous
initiation; Note=Translation N-terminally shortened;
Secondary accessions: O60534 Q4LE29 Q53EU4
Alternative splicing: 2 isoforms:  Q6ZSZ6-1   Q6ZSZ6-2   

Explore the universe of human proteins at neXtProt for TSHZ1: NX_Q6ZSZ6

Explore proteomics data for TSHZ1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZSZ6

  • TSHZ1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TSHZ1 Protein Expression
    REFSEQ proteins: NP_005777.3  
    ENSEMBL proteins: 
     ENSP00000323584   ENSP00000464391   ENSP00000453834   ENSP00000452718  

    Human Recombinant Protein Products for TSHZ1: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TSHZ1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    TSHZ1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZFHX: Homeoboxes / ZF class
    TSHZ: Teashirt zinc fingers

    5/6 InterPro protein domains (see all 6):
     IPR015880 Znf_C2H2-like
     IPR026808 Tshz1
     IPR027008 Teashirt_fam
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q6ZSZ6

    ProtoNet protein and cluster: Q6ZSZ6

    UniProtKB/Swiss-Prot: TSH1_HUMAN, Q6ZSZ6
    Similarity: Belongs to the teashirt C2H2-type zinc-finger protein family
    Similarity: Contains 5 C2H2-type zinc fingers
    Similarity: Contains 1 homeobox DNA-binding domain


    TSHZ1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TSH1_HUMAN, Q6ZSZ6
    Function: Probable transcriptional regulator involved in developmental processes. May act as a transcriptional
    repressor (Potential)

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding ----
    GO:0043565sequence-specific DNA binding IEA--
         
    TSHZ1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TSHZ1:
     Decreased Hepatitis C virus re 

         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tshz1):
     behavior/neurological  craniofacial  digestive/alimentary  hearing/vestibular/ear  mortality/aging 
     respiratory system  skeleton 

    TSHZ1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tshz1tm1Core for TSHZ1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TSHZ1 
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    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate TSHZ1 (see all 48):
    hsa-miR-411* hsa-miR-323-3p hsa-miR-379* hsa-miR-301a hsa-miR-764 hsa-miR-570 hsa-miR-124 hsa-miR-629
    SwitchGear 3'UTR luciferase reporter plasmidTSHZ1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSHZ1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TSHZ1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TSHZ1 (Q6ZSZ63 ENSP000003235844) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APBB1O002133, ENSP000002994024I2D: score=1 STRING: ENSP00000299402
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0009952anterior/posterior pattern specification IEA--
    GO:0010468regulation of gene expression ----
    GO:0042474middle ear morphogenesis IEA--

    TSHZ1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TSHZ1 (TSH1)

    Search CenterWatch for drugs/clinical trials and news about TSHZ1 / TSH1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TSHZ1 gene: 
    NM_005786.5  

    Unigene Cluster for TSHZ1:

    Teashirt zinc finger homeobox 1
    Hs.284217  [show with all ESTs]
    Unigene Representative Sequence: AB210042
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322038(uc002lly.3) ENST00000580243 ENST00000560918 ENST00000560661
    ENST00000584217(uc021uln.1)

    miRNA
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    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate TSHZ1 (see all 48):
    hsa-miR-411* hsa-miR-323-3p hsa-miR-379* hsa-miR-301a hsa-miR-764 hsa-miR-570 hsa-miR-124 hsa-miR-629
    SwitchGear 3'UTR luciferase reporter plasmidTSHZ1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    GenScript: all cDNA clones in your preferred vector: TSHZ1 (NM_005786)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSHZ1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSHZ1
    Sirion Biotech Customized lentivirus for stable overexpression of TSHZ1 
                         Customized lentivirus expression plasmids for stable overexpression of TSHZ1 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TSHZ1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSHZ1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSHZ1

    Additional mRNA sequence: 

    AB210042.1 AF039698.1 AK127042.1 AK223545.1 AL833321.1 BC010679.2 BC024152.2 

    9 DOTS entries:

    DT.114292  DT.97794820  DT.102827466  DT.95273705  DT.40198231  DT.100009543  DT.91663127  DT.95273704 
    DT.92002331 

    24/121 AceView cDNA sequences (see all 121):

    NM_005786 W01027 AA127183 N73862 AW150420 BM973845 AL833321 CA448119 
    AA975279 AI363032 BF477380 H80280 BU689131 AW614927 BM668248 D61613 
    BC010679 BQ954170 AW293262 BC024152 N48543 BG059915 BE731871 BP341276 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TSHZ1 expression in normal human tissues (normalized intensities)      TSHZ1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTTCTTGA
    TSHZ1 Expression
    About this image


    TSHZ1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Nose (Sensory Organs)
             sensory organ/nose/nasal cavity   
     
     Bone (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Cartilage (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Fibroblast
             Human Dermal Fibroblasts-neonate (HDF-n)   

    See TSHZ1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TSHZ1

    SOURCE GeneReport for Unigene cluster: Hs.284217

    UniProtKB/Swiss-Prot: TSH1_HUMAN, Q6ZSZ6
    Tissue specificity: Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease

        SABiosciences Expression via Pathway-Focused PCR Array including TSHZ1: 
              Polycomb & Trithorax Target Genes in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSHZ1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TSHZ1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tshz11 , 5 teashirt zinc finger family member 11, 5 85.9(n)1
    92.92(a)1
      18 (57.53 cM)5
    1107961  NM_001081300.11  NP_001074769.11 
     840116275 
    chicken
    (Gallus gallus)
    Aves TSHZ11 teashirt zinc finger homeobox 1 78.32(n)
    88.54(a)
      428513  XM_426067.2  XP_426067.2 
    lizard
    (Anolis carolinensis)
    Reptilia TSHZ16
    Uncharacterized protein
    83(a)
    1 ↔ 1
    4(49803101-49895215)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.144302 Transcribed sequence 80.55(n)    BX698934.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sdccag332 serologically defined colon cancer antigen 33 78.03(n)   369196  AF242292.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta tio6
    tsh6
    teashirt
    11(a)
    10(a)
    many ↔ many
    many ↔ many
    2L(22020035-22024313)
    2L(21828593-21837011)


    ENSEMBL Gene Tree for TSHZ1 (if available)
    TreeFam Gene Tree for TSHZ1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TSHZ1 gene
    TSHZ32  TSHZ22  
    2 SIMAP similar genes for TSHZ1 using alignment to 4 protein entries:     TSH1_HUMAN (see all proteins):
    TSHZ3    TSHZ2

    TSHZ1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1881 SNPs in TSHZ1 are shown (see all 1881)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3743942321,2
    C--69607657(+) GTTTG-/AG/G  
            
    GGGGG
    2 -- ut510--------
    rs1502175321,2
    C--69634602(+) ctttc-/TTTCATTT/TTTTA
    TTT
    /TTTTATTTATTT
    attta
    2 -- int1 cds10--------
    rs118748501,2
    H--69639175(+) AGGCAC/GTTACT 1 -- int10--------
    rs2017591061,2
    C--72774728(+) TCAGGG/TTGACG 1 -- us2k10--------
    rs2008888301,2
    C--72774772(+) ACCAGA/CTTCTG 1 -- us2k10--------
    rs1998526671,2
    C--72774971(+) TAGGG-/GGGCGG 1 -- us2k10--------
    rs1819177651,2
    --72775175(+) GGTGTC/TCCGGC 1 -- us2k10--------
    rs14402981,2
    C,F--72775518(+) TCCTTG/CCAAGG 1 -- us2k14Minor allele frequency- C:0.05MN NA WA 308
    rs1857224381,2
    --72775589(+) GGGCGA/GGGAGC 1 -- us2k10--------
    rs1421212721,2
    --72775599(+) CCCTG-/CCCGCC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TSHZ1 (72922710 - 73001905 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TSHZ1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv458299CNV Loss19166990
    nsv132104CNV Loss16902084
    nsv132006CNV Loss16902084
    nsv833695CNV Gain17160897
    nsv909924CNV Gain21882294


    Human Gene Mutation Database (HGMD): TSHZ1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TSHZ1
    DNA2.0 Custom Variant and Variant Library Synthesis for TSHZ1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614427    OMIM disorders: --

    UniProtKB/Swiss-Prot: TSH1_HUMAN, Q6ZSZ6
  • Aural atresia, congenital (CAA) [MIM:607842]: A rare anomaly of the ear that involves some degree of
    failure of the development of the external auditory canal. The malformation can also involve the tympanic
    membrane, ossicles and middle ear space. The inner ear development is most often normal. Different CAA forms are
    known. CAA type I is characterized by bony or fibrous atresia of the lateral part of the external auditory canal
    and an almost normal medial part and middle ear. CAA type II is the most frequent type and is characterized by
    partial or total aplasia of the external auditory canal. CAA type IIA involves an external auditory canal with
    either complete bony atresia of the medial part or partial aplasia that ends blindly in a fistula leading to a
    rudimentary tympanic membrane. CAA type IIB is characterized by bony stenosis of the total length of the external
    auditory canal. CAA type III involves bony atresia of the external auditory canal and a very small or absent
    middle-ear cavity. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 8 diseases for TSHZ1:    About MalaCards
    congenital aural atresia    microtia    colon cancer    thyroid hormone resistance syndrome
    intellectual disability    blindness    thyroiditis    alzheimer's disease


    TSHZ1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): TSHZ1
    Human Genome Epidemiology (HuGE) Navigator: TSHZ1 (1 document)

    Export disorders for TSHZ1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TSHZ1 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with TSHZ1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Disruption of teashirt zinc finger homeobox 1 is asso ciated with congenital aural atresia in humans. (PubMed id 22152683)1, 2 Feenstra I....Cremers C.W. (2011)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. FE65 binds Teashirt, inhibiting expression of the pri mate-specific caspase-4. (PubMed id 19343227)1, 2 Kajiwara Y....Buxbaum J.D. (2009)
    4. Tshz1 is required for axial skeleton, soft palate and middle ear development in mice. (PubMed id 17586487)1, 3 Core N....Fasano L. (2007)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Characterization of human colon cancer antigens recognized by autologous antibodies. (PubMed id 9610721)1, 2 Scanlan M.J....Old L.J. (1998)
    7. Genetic variants associated with disordered eating. (PubMed id 23568457)1 Wade T.D....Martin N.G. (2013)
    8. Genome-wide copy number profiling using a 100K SNP ar ray reveals novel disease-related genes BORIS and TSHZ1 in juvenile angiofibrom a. (PubMed id 21874228)1 Schick B....Wendler O. (2011)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10194 HGNC: 10669 AceView: SDCCAG33 Ensembl:ENSG00000179981 euGenes: HUgn10194
    ECgene: TSHZ1 H-InvDB: TSHZ1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TSHZ1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TSHZ1 gene:
    Search GeneIP for patents involving TSHZ1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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