TSHB Gene
protein-coding GIFtS: 62
GCID: GC01P115572
|
|
thyroid stimulating hormone, beta
| |
Aliases for TSHB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Thyroid Stimulating Hormone, Beta1 2 | | Thyrotropin Beta Subunit2 | | Thyroid-Stimulating Hormone Subunit Beta2 3 | | Thyrotropin Subunit Beta2 | | Thyrotropin Beta Chain2 3 | | TSH-Beta1 | | TSH-B2 3 | | Thyrotropin Alfa3 | | TSH-BETA2 | | CHNG45 |
Export aliases for TSHB gene to outside databasesPrevious GC identifers: GC01P115989 GC01P114458 GC01P114672 GC01P114874 GC01P114871 GC01P115284 GC01P113430 |
Summaries for TSHB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for TSHB: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulatinghormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that areassociated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are uniqueand confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure andmetabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in thisgene result in congenital hypothyroidism.(provided by RefSeq, Nov 2009) UniProtKB/Swiss-Prot: TSHB_HUMAN, P01222Function: Indispensable for the control of thyroid structure and metabolism Gene Wiki entry for TSHB
|
Genomic Views for TSHB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TSHB gene promoter: AP-1 ATF-2 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) Nkx2-5 E4BP4 POU3F2 POU2F1 POU2F1a c-Jun Other transcription factors
Search SABiosciences Chromatin IP Primers for TSHB
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSHB |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p13 Ensembl cytogenetic band: 1p13.2 HGNC cytogenetic band: 1p13TSHB Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P115572: view genomic region
(about GC identifiers)
Start:
|
115,572,415 bp from pter |
End:
|
115,576,941 bp from pter |
Size:
|
4,527 bases |
Orientation:
|
plus strand |
|
Proteins for TSHB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: TSHB_HUMAN, P01222 (See
protein sequence)Recommended Name: Thyrotropin subunit beta precursor Size: 138 amino acids; 15639 Da
Subunit: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity tothyrotropin, lutropin, follitropin and gonadotropin
Subcellular location: Secreted
Secondary accessions: B1AKP0 Q16163Explore the universe of human proteins at neXtProt for TSHB: NX_P01222
TSHB Protein expression data from MOPED and PaxDb: About this image 

REFSEQ proteins: NP_000540.2 ENSEMBL proteins: ENSP00000358530 ENSP00000256592 Reactome Protein details: P01222 Human Recombinant Protein Products for TSHB:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
TAS | -- |
TSHB for ontologies About GeneDecksing
TSHB Antibody Products: Assay Products for TSHB: |
Protein
Domains / Families for TSHB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TSHB for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P01222ProtoNet protein and cluster: P01222 3 Blocks protein families: IPB001545 Gonadotropin IPB002400 Growth factor cystine knot superfamily signature IPB006208 Cystine knot domain
UniProtKB/Swiss-Prot: TSHB_HUMAN, P01222Similarity: Belongs to the glycoprotein hormones subunit beta family |
Function for TSHB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: TSHB_HUMAN, P01222Function: Indispensable for the control of thyroid structure and metabolism Genatlas biochemistry entry for TSHB:thyroid stimulating hormone,beta polypeptide,thyroid hormones,secretion and metabolic pathway
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005179 | hormone activity |
IEA | -- |
TSHB for ontologies About GeneDecksing
Phenotypes: 3 GenomeRNAi human phenotypes for TSHB: Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TSHB (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TSHB OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TSHB (NM_000549) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TSHB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSHB  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSHB |
|
Pathways & Interactions for TSHB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glycoprotein hormones | | | 2 | Class A/1 (Rhodopsin-like receptors) | | | 3 | Signaling by GPCR | | | 4 | TSH signaling pathway | | | 5 | Allograft rejection | |
Pathway sources See GeneCards unified pathways Show all pathways
1 BioSystems Pathway for TSHB 
5/11
Reactome Pathways for TSHB (see all 11)
2
Kegg Pathways (Kegg details for TSHB):
TSHB for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TSHB
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
 2 Interacting proteins for TSHB (P012223 ENSP000002565924) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
TSHB for ontologies About GeneDecksing
|
Drugs & Compounds for TSHB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TSHB for compounds About GeneDecksing
Browse Tocris compounds for TSHB UniProtKB/Swiss-Prot: TSHB_HUMAN, P01222Pharmaceutical: Available under the name Thyrogen (Genzyme). Used in combination with other tests to detect recurringor leftover thyroid cancer cells in patients with a history of certain types of thyroid cancer 9 Novoseek chemical compound relationships for TSHB gene About this table
Search CenterWatch for drugs/clinical trials and news about TSHB 
|
Transcripts for TSHB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for TSHB gene: NM_000549.3 Unigene Cluster for TSHB: Thyroid stimulating hormone, beta Hs.406687 [show with all ESTs]Unigene Representative Sequence: AV7522952 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369517 ENST00000256592(uc001efs.1)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TSHB (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TSHB OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TSHB (NM_000549) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TSHB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSHB  |
Additional cDNA sequence: BC069298.1 S51112.1 3 DOTS entries: DT.108204 DT.97823333 DT.97824407 5 AceView cDNA sequences: BG202613 NM_000549 BC069298 AV745295 AV750117 GeneLoc Exon Structure
|
Expression for TSHB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TSHB expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AAGCCATCAA
 About this image See TSHB Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TSHB
SOURCE GeneReport for Unigene cluster: Hs.406687 SABiosciences Custom PCR Arrays for TSHB
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TSHB Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TSHB | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSHB | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSHB | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSHB |
Orthologs for TSHB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TSHB gene from 4/13 species (see all 13) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
TSHB1 |
thyroid stimulating hormone, beta |
70.51(n) 70.77(a) |
  |
395937 NM_205063.1 NP_990394.1 |
lizard (Anolis carolinensis) |
Reptilia |
TSHB6 |
-- |
65(a) |
1 ↔ 1 |
4(130658666-130660786) |
African clawed frog (Xenopus laevis) |
Amphibia |
L07618.12 |
-- |
72.62(n) |
  |
L07618.1 |
zebrafish (Danio rerio) |
Actinopterygii |
tshb1 |
thyroid stimulating hormone, beta subunit |
56.18(n) 48.39(a) |
  |
353223 NM_181494.2 NP_852471.1 |
ENSEMBL Gene Tree for TSHB (if available) TreeFam Gene Tree for TSHB (if available)  |
Paralogs for TSHB gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for TSHB gene
- FSHB2 CGB22 LHB2 CGB82 ENSG000002673352 CGB52 CGB2 CGB72
- CGB12
8 SIMAP similar genes for TSHB using alignment to 1 protein entry: TSHB_HUMAN:FSHB CGB CGB1 CGB2 CGB5 CGB8 CGB7 LHB
TSHB for paralogs About GeneDecksing
|
Genomic Variants for TSHB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for TSHB (115572415 - 115576941 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for TSHB 3 CNVs: 64659 2322 3306 Human Gene Mutation Database (HGMD): TSHB
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TSHB |
|
Disorders
/ Diseases for TSHB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TSHB for disorders About GeneDecksing
OMIM gene information: 188540 OMIM disorders: 275100 20 diseases for TSHB: About MalaCardsthyroiditis hypothryoidism, congenital, nongoitrous 4 congenital hypothyroidism hypothyroidism tsh producing pituitary tumor pituitary hormone deficiency combined pituitary hormone deficiency suprasellar meningioma sex reversal panhypopituitarism pituitary tumor pituitary adenoma familial hypothyroidism adenoma autoimmune thyroiditis graves' disease goiter thyroid cancer meningioma hepatitis 6 diseases from the University of Copenhagen DISEASES database for TSHB:Hypothyroidism Pituitary adenoma Adenoma Suprasellar meningioma Hyperthyroidism Goiter 10 Novoseek disease relationships for TSHB gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tsh deficiency |
95 |
5 |
1811097 (1), 8254929 (1), 2401711 (1), 8196185 (1) (see all 5) |
| panhypopituitarism |
82.5 |
1 |
18653712 (1) |
| congenital hypothyroidism |
72.8 |
3 |
15292359 (1), 8848697 (1), 9806481 (1) |
| hypothyroidism |
65.2 |
11 |
11297590 (2), 16804796 (2), 15297803 (2), 9039330 (1) (see all 7) |
| pituitary adenoma |
65.2 |
3 |
7543115 (2), 9039330 (1) |
| pituitary tumors |
64.7 |
1 |
7859921 (1) |
| adenoma |
45.7 |
20 |
8949563 (5), 9820613 (4), 9666878 (1), 12714791 (1) (see all 5) |
| rare disease |
13.1 |
1 |
16804796 (1) |
| hyperthyroidism |
12.8 |
1 |
9039330 (1) |
| tumors |
1.85 |
12 |
11081157 (3), 8077322 (2), 9003007 (1), 1310694 (1) (see all 5) |
Genatlas disease: TSHB hypothyroidism,pituitary,familial Genetic Association Database (GAD): TSHB Human Genome Epidemiology (HuGE) Navigator: TSHB (6 documents) Export disorders for TSHB gene to outside databases
|
Publications for TSHB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TSHB gene, integrated from 9 sources (see all 127): (articles sorted by number of sources associating them with TSHB) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species. (PubMed id 2457586)1, 2, 3 Wondisford F.E.... Weintraub B.D. (1988)
- The structure of the human thyrotropin beta-subunit gene. (PubMed id 3243440)1, 2, 3 Tatsumi K.... Matsubara K. (1988)
- Compound heterozygous and homozygous mutations of the TSHbeta gene as a cause of congenital central hypothyroidism in Europe. (PubMed id 15297803)1, 4, 9 Karges B....Karges W. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Congenital central hypothyroidism due to homozygous thyrotropin beta 313 Delta T mutation is caused by a Founder effect. (PubMed id 12364478)1, 4 Brumm H....Gruters A. (2002)
- Structure and regulation of human thyroid-stimulating hormone (TSH) gene. (PubMed id 8196184)1, 2 Miyoshi I.... Hayashizaki Y. (1994)
- The human thyrotropin beta-subunit gene differs in 5' structure from murine TSH-beta genes. (PubMed id 3234176)1, 2 Guidon P.T. Jr.... Kourides I.A. (1988)
- Molecular cloning of the human thyrotropin-beta subunit gene. (PubMed id 3839756)1, 2 Hayashizaki Y.... Matsubara K. (1985)
- Human pituitary thyrotropin. The primary structure of the alpha and beta subunits. (PubMed id 890569)1, 2 Sairam M.R. and Li C.H. (1977)
- A novel thyroid stimulating hormone beta-subunit isoform in human pituitary, peripheral blood leukocytes, and thyroid. (PubMed id 19364510)1, 9 Schaefer J.S. and Klein J.R. (2009)
|
External Searches for TSHB gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing TSHB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TSHB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TSHB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for TSHB | Pharmacogenomics, SNPs, Pathways | | Thyrogen | http://www.thyrogen.com/home/thy_home.asp | | Wikipedia | http://en.wikipedia.org/wiki/Thyroid-stimulating_hormone |
|
| | |
About This Section
| Patent Information for TSHB gene: Search GeneIP for patents involving TSHB
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for TSHB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for TSHB | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TSHB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TSHB | | OriGene Protein Over-expression Lysate for TSHB | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for TSHB | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TSHB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TSHB | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for TSHB | | OriGene Custom Protein Services for TSHB | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TSHB | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TSHB | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSHB | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TSHB | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TSHB | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TSHB |
| |
 |  |  |  | |
| | | Search Tocris compounds for TSHB |
| |  |  |  |  | | | | | Recombinant Protein for TSHB |
|
 |
 |
 |
 | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSHB |
|  |  |  |  | | | ThermoFisher Antibody for TSHB |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSHB |
| |  | |
|
|
|