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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TSGA13 Gene

protein-coding GIFtS: 36
GCID: GC07M130353

testis specific, 13

Search for TSGA13
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Testis Specific, 13¹ ²
Testis-Specific A13²
Testis-Specific Gene 13 Protein²

External Ids:	HGNC: 12369¹	Entrez Gene: 114960²	Ensembl: ENSG00000213265⁷	UniProtKB: Q96PP4³

Export aliases for TSGA13 gene to outside databases

Previous GC identifers: GC07M128693 GC07M129755 GC07M129769 GC07M129703 GC07M129753 GC07M129810 GC07M129934 GC07M130004 GC07M124668

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TSGA13 gene promoter:
TBP RFX1 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 HNF-1A TFIID HNF-1 FOXO1a FOXO1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TSGA13 promoter sequence

Search SABiosciences Chromatin IP Primers for TSGA13

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSGA13

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q32 Ensembl cytogenetic band: 7q32.2 HGNC cytogenetic band: 7q32

TSGA13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSGA13 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M130353: view genomic region (about GC identifiers)

Start:	130,353,486 bp from pter	End:	130,372,268 bp from pter
Size:	18,783 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 129,689,988-129,707,909

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TSG13_HUMAN, Q96PP4 (See protein sequence)

Recommended Name: Testis-specific gene 13 protein

Size: 275 amino acids; 31778 Da

Secondary accessions: B3KSC9

Explore the universe of human proteins at neXtProt for TSGA13: NX_Q96PP4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96PP4

TSGA13 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_443165.1

ENSEMBL proteins:

ENSP00000406047 ENSP00000402098 ENSP00000348996 ENSP00000415856 ENSP00000407352

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q96PP4

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TSGA13

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TSGA13
Search CenterWatch for drugs/clinical trials and news about TSGA13 / TSG13

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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About This Section

REFSEQ mRNAs for TSGA13 gene:

NM_052933.2

Unigene Cluster for TSGA13:

Testis specific, 13

Hs.592266 [show with all ESTs]

Unigene Representative Sequence: AK093329

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000456951(uc003vqi.3 uc003vqj.3) ENST00000418126 ENST00000356588

ENST00000443954 ENST00000438346

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Additional cDNA sequence:

AF294347.1 AF431815.1 AK093329.1 BC038415.1

4 DOTS entries:

DT.100044641 DT.95094686 DT.95328531 DT.121100561

24/91 AceView cDNA sequences (see all 91):

BI826509 AF431815 BU501717 BQ286198 BQ269562 AW779612 BU621332 AA774034

BI222381 CR593178 AF294347 BU689642 BU952531 BQ949550 BE255440 BQ049150

AI566718 AI198538 BX375975 BM714405 BE253295 BI829418 BI754883 AX748057

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TSGA13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

TSGA13 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Somite

Lumbar Vertebral Body

Somite

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TSGA13 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TSGA13

SOURCE GeneReport for Unigene cluster: Hs.592266

UniProtKB/Swiss-Prot: TSG13_HUMAN, Q96PP4

Tissue specificity: Testis-specific

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for TSGA13 gene from 1/6 species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tsga13^{1 , 5}	testis specific gene A13^{1, 5}	74.66(n)¹ 59.78(a)¹		6 (12.54 cM)⁵ 116732¹ NM_054073.2¹ NP_473414.1¹ 30896981⁵

ENSEMBL Gene Tree for TSGA13 (if available)
TreeFam Gene Tree for TSGA13 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs77677084^1,2	C,	--	124671214(+)	`ATGATC/GTGTTT`	1	--	int¹		1		WA	118
rs6953927^1,2	A	--	124672317(+)	`accacA/Gcctgg`	1	--	int¹		0	--	--	--	--
rs78160016^1,2		--	124673331(+)	`ACACTA/CTTTTC`	1	--	int¹		0	--	--	--	--
rs76668322^1,2	F,	--	124673720(+)	`CAATCT/CTTCTT`	1	--	int¹		3		CSA WA	122
rs111278848^1,2	F,	--	124674304(+)	`AGGTTG/ACAGTG`	1	--	int¹		2		CSA	4
rs112256223^1,2		--	124675008(+)	`ATACTT/CGCTGC`	1	--	int¹		2		CSA WA	120
rs6969737^1,2	C,F,A,H,	--	124675448(+)	`TGTGTA/GTATAT`	1	--	int¹		17		NS EA NA CSA WA	2138
rs11979494^1,2	C,H,	--	124675993(+)	`ACCTGG/AAAACA`	1	--	int¹		5		NA WA	244
rs113370252^1,2		--	124676136(+)	`TTGTTG/TGGTCT`	1	--	int¹		2		CSA WA	120
rs75745176^1,2		--	124676566(+)	`ACAATA/TTAACT`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TSGA13 (130353486 - 130372268 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TSGA13
1 CNV: 4560

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TSGA13 for disorders About MalaCards

TSGA13 for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: TSGA13 (1 document)

Export disorders for TSGA13 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TSGA13 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TSGA13)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)^{1, 2} Scherer S.W.... Tsui L.-C. (2003)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST- flanking region at human chromosome 7q32. (PubMed id 14962666)¹ Yamada T.... Kishino T. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 114960	HGNC: 12369	AceView: COPG2	Ensembl:ENSG00000213265	euGenes: HUgn114960
ECgene: TSGA13	H-InvDB: TSGA13

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TSGA13	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TSGA13 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for TSGA13 gene:
Search GeneIP for patents involving TSGA13

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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About This Section


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TSGA13 Gene

testis specific, 13

Aliases
for TSGA13 gene

Summaries
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TSGA13 Gene

testis specific, 13

Aliasesfor TSGA13 gene

Summariesfor TSGA13 gene

Genomic Viewsfor TSGA13 gene

Proteinsfor TSGA13 gene

Protein Domains /Familiesfor TSGA13 gene

Functionfor TSGA13 gene

Pathways & Interactionsfor TSGA13 gene

Drugs & Compoundsfor TSGA13 gene

Transcriptsfor TSGA13 gene

Expression for TSGA13 gene

Orthologsfor TSGA13 gene

Paralogsfor TSGA13 gene

Genomic Variantsfor TSGA13 gene

Disorders / Diseasesfor TSGA13 gene

Publicationsfor TSGA13 gene

External Searches for TSGA13 gene

Genome Databases showing TSGA13 gene

Other Databases showing TSGA13 gene

Specialized Databases showing TSGA13 gene

Intellectual Propertyfor TSGA13 gene

Productsfor TSGA13 gene

View Random Gene

Aliases
for TSGA13 gene

Summaries
for TSGA13 gene

Genomic Views
for TSGA13 gene

Proteins
for TSGA13 gene

Protein Domains /
Families
for TSGA13 gene

Function
for TSGA13 gene

Pathways & Interactions
for TSGA13 gene

Drugs & Compounds
for TSGA13 gene

Transcripts
for TSGA13 gene

Expression
for TSGA13 gene

Orthologs
for TSGA13 gene

Paralogs
for TSGA13 gene

Genomic Variants
for TSGA13 gene

Disorders / Diseases
for TSGA13 gene

Publications
for TSGA13 gene

Intellectual Property
for TSGA13 gene

Products
for TSGA13 gene