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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TSEN15 Gene

protein-coding   GIFtS: 51
GCID: GC01P184020

tRNA splicing endonuclease 15 homolog (S. cerevisiae)

(Previous name: chromosome 1 open reading frame 19 )
(Previous symbol: C1orf19)
 Explore 4 diseases affiliated with
TSEN15 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TSEN15    

Aliases
for TSEN15 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
TRNA Splicing Endonuclease 15 Homolog (S. Cerevisiae)1 2     HsSen151
C1orf191 2 3     Sen151
SEN15 Homolog2 3     TRNA-Splicing Endonuclease Subunit Sen152
TRNA-Intron Endonuclease Sen152 3     HsSEN153
Chromosome 1 Open Reading Frame 191     SEN153

External Ids:    HGNC: 167911   Entrez Gene: 1164612   Ensembl: ENSG000001988607   OMIM: 6087565   UniProtKB: Q8WW013   
ORGUL members:         
NONCODE:n406458    

Export aliases for TSEN15 gene to outside databases

Previous GC identifers: GC01P182288 GC01P155256


Summaries
for TSEN15 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TSEN15:
tRNA splicing is a fundamental process required for cell growth and division. SEN15 is a subunit of the tRNA splicing
endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004 (PubMed
15109492)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: SEN15_HUMAN, Q8WW01
Function: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and
cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The
products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no
conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing
the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing
endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors,
establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits
function in multiple RNA-processing events

Gene Wiki entry for TSEN15 (C1orf19)


Genomic Views
for TSEN15 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TSEN15 gene promoter:
         AP-2rep   HFH-3   Nkx2-5   POU6F1 (c2)   E4BP4   FOXI1   FOXC1   HFH-1   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TSEN15 promoter sequence
   Search SABiosciences Chromatin IP Primers for TSEN15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TSEN15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q25   Ensembl cytogenetic band:  1q25.3   HGNC cytogenetic band: 1q25

TSEN15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSEN15 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P184020:  view genomic region     (about GC identifiers)

Start:
 184,020,811 bp from pter      End:
 184,043,346 bp from pter
Size:
 22,536 bases      Orientation:
 plus strand

Proteins
for TSEN15 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SEN15_HUMAN, Q8WW01 (See protein sequence)
Recommended Name: tRNA-splicing endonuclease subunit Sen15  
Size: 171 amino acids; 18641 Da
Subunit: Homodimer. tRNA splicing endonuclease is a heterotetramer composed of SEN2, SEN15, SEN34/LENG5 and SEN54. tRNA
splicing endonuclease complex also contains proteins of the Pre-mRNA 3' end processing machinery such as CLP1, CPSF1,
CPSF4 and CSTF2
Subcellular location: Nucleus (Probable). Nucleus, nucleolus (Probable). Note=May be transiently localized in the
nucleolus (Probable)
Caution: Although only weakly related to the S.cerevisiae SEN15 protein, it probably displays the same function within
the tRNA splicing endonuclease complex
Sequence caution: Sequence=AAG60614.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for TSEN15:
2GW6 (3D)    
Secondary accessions: B4DKP0 Q9BZQ5
Alternative splicing: 2 isoforms:  Q8WW01-1   Q8WW01-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TSEN15: NX_Q8WW01

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8WW01

    • TSEN15 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001120866.1  NP_443197.1  

    ENSEMBL proteins: 
     ENSP00000355299   ENSP00000435144   ENSP00000436996   ENSP00000402002   ENSP00000432397  

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    Novus Biologicals TSEN15 Lysates
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    ProSpec Recombinant Protein for TSEN15
    Uscn Proteins for TSEN15

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--


    TSEN15 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for TSEN15

    Protein Domains /
    Families
    for TSEN15 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TSEN15 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR024369 tRNA-intron_endonuclease_Sen15

    Graphical View of Domain Structure for InterPro Entry Q8WW01

    ProtoNet protein and cluster: Q8WW01

    UniProtKB/Swiss-Prot: SEN15_HUMAN, Q8WW01
    Similarity: Belongs to the SEN15 family


    Function
    for TSEN15 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SEN15_HUMAN, Q8WW01
    Function: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and
    cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The
    products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no
    conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing
    the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing
    endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors,
    establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits
    function in multiple RNA-processing events

    miRNA
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    hsa-miR-548g hsa-miR-4251 hsa-miR-616* hsa-miR-340 hsa-miR-2113 hsa-miR-371-5p hsa-miR-373* hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmid: TSEN15 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Pathways & Interactions
    for TSEN15 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TSEN15

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/9 Interacting proteins for TSEN15 (Q8WW012, 3 ENSP000003552994) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LMO4P619682, 3MINT-60892 I2D: score=3 
    TSEN34Q9BSV63, ENSP000003055244I2D: score=2 STRING: ENSP00000305524
    EXOSC4Q9NPD33, ENSP000003154764I2D: score=2 STRING: ENSP00000315476
    CLP1Q929893, ENSP000003047044I2D: score=1 STRING: ENSP00000304704
    TSEN2Q8NCE03, ENSP000002849954I2D: score=1 STRING: ENSP00000284995
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006397mRNA processing IEA--
    GO:0008033tRNA processing IEA--


    TSEN15 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TSEN15 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TSEN15
    Search CenterWatch for drugs/clinical trials and news about TSEN15 / SEN15 

    Transcripts
    for TSEN15 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TSEN15 gene (2 alternative transcripts): 
    NM_001127394.2  NM_052965.2  

    Unigene Cluster for TSEN15:

    TRNA splicing endonuclease 15 homolog (S. cerevisiae)
    Hs.548197  [show with all ESTs]
    Unigene Representative Sequence: NR_023349
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361641(uc009wyg.3 uc001gqt.4 uc001gqu.4) ENST00000485209
    ENST00000533373 ENST00000367518 ENST00000423085 ENST00000462677 ENST00000457455


    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate TSEN15:
    hsa-miR-548g hsa-miR-4251 hsa-miR-616* hsa-miR-340 hsa-miR-2113 hsa-miR-371-5p hsa-miR-373* hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmid: TSEN15 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TSEN15 (see all 4)
    OriGene shRNA RFP: TSEN15
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): TSEN15 (NM_052965)
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    Primer
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    Additional cDNA sequence: 

    AF288394.1 AK098196.1 AK296655.1 AK307241.1 BC022030.1 NR_023349.1 

    11 DOTS entries:

    DT.208943  DT.443301  DT.97858804  DT.95082653  DT.100789785  DT.100035818  DT.100789786  DT.40128007 
    DT.100035815  DT.443299  DT.101964593 

    24/186 AceView cDNA sequences (see all 186):

    AI524582 BF109586 AI720184 AA994567 BP341942 BM801842 BI821111 AI418101 
    AA194112 BU622552 CA429134 BF476359 BF001598 BE670994 BU166129 BF511051 
    AI198454 AI167587 BM993844 BF433006 AI141865 AW137283 CR612120 BE500978 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for TSEN15 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b · 7c · 7d · 7e · 7f
    SP1:                                                        -     -                       -     -                                       
    SP2:                                                  -     -     -                       -     -                                       
    SP3:                                                  -     -     -           -     -     -     -                                       
    SP4:                                                  -     -     -                             -                                       
    SP5:                                                  -           -                                                                     


    ECgene alternative splicing isoforms for TSEN15

    Expression
    for TSEN15 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TSEN15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCTGAAATAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See TSEN15 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TSEN15

    SOURCE GeneReport for Unigene cluster: Hs.548197

    UniProtKB/Swiss-Prot: SEN15_HUMAN, Q8WW01
    Tissue specificity: Widely expressed. Highly expressed in testis and uterus

        SABiosciences Custom PCR Arrays for TSEN15
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    In Situ
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    Orthologs
    for TSEN15 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for TSEN15 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Tsen151 , 5 tRNA splicing endonuclease 15 homolog (S. cerevisiae)1, 5 88.49(n)1
    92.86(a)1    		   1 (64.75 cM)5
    666371  NM_025677.31  NP_079953.21 
     1523707355 
    chicken
    (Gallus gallus)    		 Aves TSEN151 tRNA splicing endonuclease 15 homolog (S. cerevisiae) 62.85(n)
    56.69(a)    		   424448  XM_003641664.1  XP_003641712.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii tsen151 tRNA splicing endonuclease 15 homolog (S. cerevisiae) 51.39(n)
    48.33(a)    		   100005064  NM_001100090.1  NP_001093560.1 


    ENSEMBL Gene Tree for TSEN15 (if available)
    TreeFam Gene Tree for TSEN15 (if available) 

    Paralogs
    for TSEN15 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TSEN15 gene
    1 SIMAP similar gene for TSEN15 using alignment to 4 protein entries:     SEN15_HUMAN (see all proteins):
    C1orf19

    TSEN15 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for TSEN15
    PGOHUM00000237247 PGOHUM00000244717 PGOHUM00000232622


    Genomic Variants
    for TSEN15 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/432 NCBI SNPs in TSEN15 are shown (see all 432)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1481345101,2
    		--184018931(+) ACTAGC/TAAATG 3 -- us2k1 int10--------
    rs1419312011,2
    		--184018957(+) TTGGGA/GAAATT 3 -- us2k1 int10--------
    rs66710631,2
    		C,,--184018968(+) ctggcC/Taccac 3 -- int1 us2k10--------
    rs716943721,2
    		C,--184018974(+) ACCAC-/TCTT  
                TCTTC     		3 -- us2k1 int11Minor allele frequency- TCTT:0.50CSA 2
    rs1999008541,2
    		C--184018977(-) GAAGAA/GAGAGT 3 -- us2k1 int10--------
    rs1469761701,2
    		C,--184019000(+) GTCCC-/TTTTTT 3 -- us2k1 int10--------
    rs1885157061,2
    		--184019033(+) TGCATA/GTTGGA 3 -- us2k1 int10--------
    rs792309241,2
    		C,--184019034(+) GCATGC/TTGGAT 3 -- int1 us2k11Minor allele frequency- T:0.50WA 2
    rs1929410011,2
    		--184019154(+) TTTTTA/CTTTTG 3 -- us2k1 int10--------
    rs127598371,2
    		C,--184019184(+) AATTCA/GCCCAG 3 -- us2k1 int15Minor allele frequency- G:0.09NA WA EA 362

    HapMap Linkage Disequilibrium report for TSEN15 (184020811 - 184043346 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TSEN15: --

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    Disorders / Diseases
    for TSEN15 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TSEN15 for disorders           About GeneDecksing

    OMIM gene information: 608756    OMIM disorders: --

    4 diseases for TSEN15:    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    prostate cancer    prostatitis

    1 disease from the University of Copenhagen DISEASES database for TSEN15:
    Bartter disease
    Human Genome Epidemiology (HuGE) Navigator: TSEN15 (1 document)

    Export disorders for TSEN15 gene to outside databases

    Publications
    for TSEN15 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TSEN15 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with TSEN15)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Three-dimensional structure determined for a subunit of human tRNA splicing endonuclease (Sen15) reveals a novel dimeric fold. (PubMed id 17166513)1, 2, 3, 9 Song J. and Markley J.L. (2007)
    2. Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. (PubMed id 11318611)1, 2, 3 Sood R....Carpten J.D. (2001)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation. (PubMed id 15109492)1, 2 Paushkin S.V....Trotta C.R. (2004)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. The role of height-associated loci identified in geno me wide association studies in the determination of pediatric stature. (PubMed id 20546612)1 Zhao J....Grant S.F. (2010)
    9. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
    10. Hundreds of variants clustered in genomic loci and bi ological pathways affect human height. (PubMed id 20881960)1 Lango Allen H....Hirschhorn J.N. (2010)

    External Searches for TSEN15 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing TSEN15 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 116461 HGNC: 16791 AceView: C1orf19 Ensembl:ENSG00000198860 euGenes: HUgn116461
    ECgene: TSEN15 H-InvDB: TSEN15

    Other Databases showing TSEN15 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TSEN15 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TSEN15 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TSEN15 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TSEN15 gene:
    Search GeneIP for patents involving TSEN15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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