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TSC22D2 Gene

protein-coding   GIFtS: 47
GCID: GC03P150126

TSC22 Domain Family, Member 2

  Search for TSC22D2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TSC22 Domain Family, Member 21 2     TSC22 Domain Family 22
TSC22-Related-Inducible Leucine Zipper Protein 42 3     TSC22 Domain Family Protein 22
TILZ4a2     KIAA06693
TILZ4b2     TILZ43
TILZ4c2     

External Ids:    HGNC: 290951   Entrez Gene: 98192   Ensembl: ENSG000001964287   UniProtKB: O751573   

Export aliases for TSC22D2 gene to outside databases

Previous GC identifers: GC03P151609 GC03P147500


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TSC22D2 Gene:
TSC22D2 (TSC22 domain family, member 2) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is TSC22D3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the TSC22D2 gene promoter:
         STAT5B   GR   GR-beta   Arnt   YY1   AREB6   GR-alpha   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTSC22D2 promoter sequence
   Search Chromatin IP Primers for TSC22D2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TSC22D2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.1   Ensembl cytogenetic band:  3q25.1   HGNC cytogenetic band: 3q25.1

TSC22D2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TSC22D2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P150126:  view genomic region     (about GC identifiers)

Start:
150,126,122 bp from pter      End:
150,184,218 bp from pter
Size:
58,097 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: T22D2_HUMAN, O75157 (See protein sequence)
Recommended Name: TSC22 domain family protein 2  
Size: 780 amino acids; 79228 Da
Sequence caution: Sequence=BAA31644.2; Type=Erroneous initiation;
Secondary accessions: D3DNI5 Q6PI50 Q9H2Z6 Q9H2Z7 Q9H2Z8
Alternative splicing: 2 isoforms:  O75157-1   O75157-2   

Explore the universe of human proteins at neXtProt for TSC22D2: NX_O75157

Explore proteomics data for TSC22D2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys698
  • Modification sites at PhosphoSitePlus

  • See TSC22D2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055594.1  
    ENSEMBL proteins: 
     ENSP00000354543   ENSP00000418149   ENSP00000417747   ENSP00000420689   ENSP00000354893  

    TSC22D2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TSC22D2

     
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    Abcam antibodies for TSC22D2
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    LSBio Antibodies in human, mouse, rat for TSC22D2

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    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for TSC22D2
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    Search eBioscience for ELISAs for TSC22D2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000580 TSC-22_Dip_Bun

    Graphical View of Domain Structure for InterPro Entry O75157

    ProtoNet protein and cluster: O75157

    1 Blocks protein domain: IPB000580 TSC-22 / Dip / Bun family

    UniProtKB/Swiss-Prot: T22D2_HUMAN, O75157
    Similarity: Belongs to the TSC-22/Dip/Bun family


    Find genes that share domains with TSC22D2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
         
    Find genes that share ontologies with TSC22D2           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TSC22D2
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TSC22D2

    miRNA
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    miRTarBase miRNAs that target TSC22D2:
    hsa-mir-98-5p (MIRT027596), hsa-mir-221-3p (MIRT046928), hsa-mir-375 (MIRT019779), hsa-mir-320a (MIRT044409), hsa-mir-1227-3p (MIRT036396), hsa-mir-26b-5p (MIRT029295)

    Block miRNA regulation of human, mouse, rat TSC22D2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSC22D2 (see all 79):
    hsa-miR-140-5p hsa-miR-3152-3p hsa-miR-3146 hsa-miR-1224-3p hsa-miR-106a hsa-miR-4305 hsa-miR-1260b hsa-miR-219-5p
    SwitchGear 3'UTR luciferase reporter plasmidTSC22D2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TSC22D2
    Predesigned siRNA for gene silencing in human, mouse, rat TSC22D2

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: TSC22D2 (NM_014779)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSC22D2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSC22D2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TSC22D2
    Interactions:

        Search GeneGlobe Interaction Network for TSC22D2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for TSC22D2 (ENSP000003545434) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ETV6ENSP000002664274STRING: ENSP00000266427
    ETV7ENSP000003418434STRING: ENSP00000341843
    DHHENSP000002669914STRING: ENSP00000266991
    IHHENSP000002957314STRING: ENSP00000295731
    SHHENSP000002972614STRING: ENSP00000297261
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0006970response to osmotic stress IEA--

    Find genes that share ontologies with TSC22D2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TSC22D2 (T22D2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TSC22D2 gene: 
    NM_014779.2  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361875(uc003exv.3 uc003exw.3 uc003exx.3) ENST00000480589
    ENST00000466814 ENST00000485421 ENST00000492828 ENST00000460316 ENST00000361136

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TSC22D2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TSC22D2 (see all 79):
    hsa-miR-140-5p hsa-miR-3152-3p hsa-miR-3146 hsa-miR-1224-3p hsa-miR-106a hsa-miR-4305 hsa-miR-1260b hsa-miR-219-5p
    SwitchGear 3'UTR luciferase reporter plasmidTSC22D2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TSC22D2
    Predesigned siRNA for gene silencing in human, mouse, rat TSC22D2
    Clone
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    OriGene clones in human, mouse for TSC22D2 (see all 6)
    OriGene ORF clones in mouse, rat for TSC22D2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TSC22D2 (NM_014779)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TSC22D2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TSC22D2
    Primer
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    OriGene qPCR primer pairs and template standards for TSC22D2
    OriGene qSTAR qPCR primer pairs in human, mouse for TSC22D2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TSC22D2
      QuantiTect SYBR Green Assays in human, mouse, rat TSC22D2
      QuantiFast Probe-based Assays in human, mouse, rat TSC22D2

    Selected AceView cDNA sequences (see all 189):

    BE840400 AK123861 BE840394 BE840305 AA993976 AW276993 BE840317 AA233767 
    BE840388 BM984748 BQ447360 BE840397 BE840372 AF201292 BE840373 AA962731 
    BE812057 AW270114 AA040290 BC044643 BE840386 AA400064 CD520523 BE840376 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TSC22D2    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d
    SP1:                                -                                 
    SP2:                          -     -                                 
    SP3:                    -     -     -                                 
    SP4:                                                                  


    ECgene alternative splicing isoforms for TSC22D2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TSC22D2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCGACTGCCT
    TSC22D2 Expression
    About this image


    TSC22D2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 11 entries
             Cerebral Cortex
             Septum   
     
     Amnion (Extraembryonic Tissues)
     
     Prostate (Endocrine System)
    TSC22D2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TSC22D2 Protein Expression
        Custom PCR Arrays for TSC22D2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TSC22D2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TSC22D2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tsc22d21 , 5 TSC22 domain family, member 21, 5 87.66(n)1
    86.96(a)1
      3 (28.51 cM)5
    720331  NM_001081229.11  NP_001074698.11 
     584156895 
    chicken
    (Gallus gallus)
    Aves LOC1008598271 TSC22 domain family protein 2-like 71.9(n)
    67.16(a)
      100859827  XM_003641785.2  XP_003641833.1 
    lizard
    (Anolis carolinensis)
    Reptilia TSC22D26
    TSC22 domain family, member 2
    62(a)
    1 ↔ 1
    3(18420901-18459983)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.177672 Transcribed sequence with weak similarity to protein more 80.9(n)    BX750066.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kiaa06692 KIAA0669 protein homolog (human) 75.16(n)   378875  AY423039.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta bun6
    bunched
    15(a)
    1 → many
    2L(12455540-12546630)
    worm
    (Caenorhabditis elegans)
    Secernentea C30G4.76
    T18D3.76
    Protein C30G4.7 (C30G4.7) mRNA, complete cds
    Protein T18D3.7, isoform a (T18D3.7) mRNA, complet...
    40(a)
    28(a)
    many ↔ many
    many ↔ many
    X(17056927-17058536) WBGene00016272
    X(12434154-12443915) WBGene00011824


    ENSEMBL Gene Tree for TSC22D2 (if available)
    TreeFam Gene Tree for TSC22D2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TSC22D2 gene
    TSC22D32  TSC22D12  TSC22D42  
    3 SIMAP similar genes for TSC22D2 using alignment to 5 protein entries:     T22D2_HUMAN (see all proteins):
    TSC22D4    TSC22D1    TSC22D3

    Find genes that share paralogs with TSC22D2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TSC22D2 (see all 947)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs755369861,2
    F--150124894(+) GAACCG/AAGTTC 1 -- us2k12Minor allele frequency- A:0.15CSA WA 120
    rs1845512041,2
    --150124940(+) GCTAAC/GGCTGC 1 -- us2k10--------
    rs1893723611,2
    --150125010(+) TTAGTA/GTGTCA 1 -- us2k10--------
    rs1999137841,2
    --150125096(+) CCCCA-/TTTTTT 1 -- us2k10--------
    rs346162871,2
    C,F--150125239(+) TTACGG/CTTGTT 1 -- us2k111Minor allele frequency- C:0.15NA EA WA CSA 610
    rs38117191,2
    C,F--150125370(+) CGAAAG/CTAAAA 1 -- us2k16Minor allele frequency- C:0.10NA WA EA 364
    rs1807552251,2
    --150125377(+) AAAACA/GGTCTC 1 -- us2k10--------
    rs1487570261,2
    C--150125486(+) AGTAAA/CCACCC 1 -- us2k10--------
    rs748518981,2
    C,F--150125574(+) AATCAT/ACCCCA 1 -- us2k12Minor allele frequency- A:0.06CSA WA 120
    rs1420332911,2
    C--150125614(+) CAATGA/GTCAAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TSC22D2 (150126122 - 150184218 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TSC22D2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv29861CNV Loss19812545
    nsv829755CNV Loss17160897
    nsv877645CNV Loss21882294
    nsv822291CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TSC22D2
    DNA2.0 Custom Variant and Variant Library Synthesis for TSC22D2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TSC22D2           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: TSC22D2 (2 documents)

    Export disorders for TSC22D2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TSC22D2 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with TSC22D2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (DNA Res. 1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination. (PubMed id 23382044)1 Hast B.E....Major M.B. (Cancer Res. 2013)
    4. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. (PubMed id 22479202)1 Dastani Z....Kathiresan S. (PLoS Genet. 2012)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in Drosophila. (PubMed id 20149264)1 Gluderer S....Stocker H. (J. Biol. 2010)
    9. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9819 HGNC: 29095 AceView: KIAA0669 Ensembl:ENSG00000196428 euGenes: HUgn9819
    ECgene: TSC22D2 H-InvDB: TSC22D2

    (According to HUGE)
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    HUGE: KIAA0669

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TSC22D2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TSC22D2 gene:
    Search GeneIP for patents involving TSC22D2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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