Aliases for TSC22D1 Gene
Aliases for TSC22D1 Gene
External Ids for TSC22D1 Gene
- HGNC: 16826
- Entrez Gene: 8848
- Ensembl: ENSG00000102804
- OMIM: 607715
- UniProtKB: Q15714
Previous HGNC Symbols for TSC22D1 Gene
- TGFB1I4
Previous GeneCards Identifiers for TSC22D1 Gene
- GC13M043906
- GC13M045007
- GC13M025809
Summaries for TSC22D1 Gene
-
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for TSC22D1 Gene
TSC22D1 (TSC22 Domain Family Member 1) is a Protein Coding gene. Diseases associated with TSC22D1 include Salivary Gland Cancer and Brain Sarcoma. Among its related pathways are Ectoderm Differentiation and Development_TGF-beta receptor signaling. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity. An important paralog of this gene is TSC22D2.
UniProtKB/Swiss-Prot for TSC22D1 Gene
-
Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
Additional gene information for TSC22D1 Gene
- Monarch Initiative
- Search for TSC22D1 at DataMed
- Search for TSC22D1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSC22D1 Gene
Genomics for TSC22D1 Gene
GeneHancer (GH) Regulatory Elements for TSC22D1 Gene
Promoters and enhancers for TSC22D1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TSC22D1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for TSC22D1 Gene
Genomic Locations for TSC22D1 Gene
- chr13:44,432,143-44,577,147
- (GRCh38/hg38)
- Size:
- 145,005 bases
- Orientation:
- Minus strand
- chr13:45,007,655-45,151,283
- (GRCh37/hg19)
Genomic View for TSC22D1 Gene
Genes around TSC22D1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q14.11 by Ensembl
- 13q14.11 by Entrez Gene
- 13q14.11 by HGNC
TSC22D1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TSC22D1 Gene
Proteins for TSC22D1 Gene
-
Protein details for TSC22D1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q15714-T22D1_HUMAN
- Recommended name:
- TSC22 domain family protein 1
- Protein Accession:
- Q15714
- B3KRL7
- B9EGI0
- O00666
- Q6AHX5
- Q6IBU1
- Q8NCN1
- Q96JS5
Protein attributes for TSC22D1 Gene
- Size:
- 1073 amino acids
- Molecular mass:
- 109677 Da
- Quaternary structure:
-
- Homodimer or heterodimer. Can form a heterodimer with TSC22D4.
- SequenceCaution:
-
- Sequence=BAC02703.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for TSC22D1 Gene
Post-translational modifications for TSC22D1 Gene
No Post-translational modifications
Other Protein References for TSC22D1 Gene
Antibody Products
- R&D Systems Antibodies for TSC22D1 (TSC22)
- Novus Biologicals Antibodies for TSC22D1
-
Abcam antibodies for TSC22D1
-
Cloud-Clone Corp. Antibodies for TSC22D1
- Invitrogen Antibodies for TSC22D1
- Search GeneTex for Antibodies for TSC22D1
-
Santa Cruz Biotechnology (SCBT) Antibodies for TSC22D1
- Sino Biological Antibodies for TSC22D1
Protein Products
-
OriGene Purified Proteins for TSC22D1
- Search Origene for MassSpec and Protein Over-expression Lysates for TSC22D1
- Origene Custom Protein Services for TSC22D1
- Sino Biological Recombinant Proteins for TSC22D1
- Browse Sino Biological Cell Lysates
-
Cloud-Clone Corp. Proteins for TSC22D1
- Search GeneTex for Proteins for TSC22D1
-
Abcam proteins for TSC22D1
Assay Products
-
Cloud-Clone Corp. Assay Kits for TSC22D1
- antibodies-online: Search results for 9 available TSC22D1 Elisa Kits ranked by validation data
- Compare Top TSC22D1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for TSC22D1 Gene
Domains & Families for TSC22D1 Gene
Gene Families for TSC22D1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for TSC22D1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TSC22D1 Gene
Graphical View of Domain Structure for InterPro Entry
Q15714- Family:
-
- Belongs to the TSC-22/Dip/Bun family.
Function for TSC22D1 Gene
Molecular function for TSC22D1 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
- UniProtKB/Swiss-Prot Induction:
- In aortic endothelial cells, induced by cytokines, including TGFB1.
Phenotypes From GWAS Catalog for TSC22D1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003700 | DNA binding transcription factor activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 18325344 |
| GO:0046983 | protein dimerization activity | IEA | -- |
Phenotypes for TSC22D1 Gene
- MGI mutant phenotypes for TSC22D1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TSC22D1:
Animal Models for TSC22D1 Gene
- MGI Knock Outs for TSC22D1:
-
- Tsc22d1 tm1Clgr
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TSC22D1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for TSC22D1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
- Search ViGene Biosciences for TSC22D1
CRISPR Products
-
OriGene CRISPR knockouts for TSC22D1
- genomics-online: gRNA clones - Search results for available TSC22D1 gene related products
- Applied Biological Materials CRISPR for TSC22D1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TSC22D1
- GenScript: Design CRISPR guide RNA sequences for TSC22D1
miRNA for TSC22D1 Gene
- miRTarBase miRNAs that target TSC22D1
-
- hsa-mir-100-5p (MIRT048416)
- hsa-mir-9-3p (MIRT441494)
- hsa-mir-590-3p (MIRT441495)
- hsa-mir-6858-5p (MIRT486471)
- hsa-mir-4689 (MIRT486472)
- hsa-mir-4784 (MIRT486473)
- hsa-mir-3150b-3p (MIRT486474)
- hsa-mir-199b-5p (MIRT486475)
- hsa-mir-199a-5p (MIRT486476)
- hsa-mir-1825 (MIRT486477)
- hsa-mir-708-5p (MIRT486478)
- hsa-mir-3139 (MIRT486479)
- hsa-mir-28-5p (MIRT486480)
- hsa-mir-6758-5p (MIRT486481)
- hsa-mir-6856-5p (MIRT486482)
miRNA Products
- Search ViGene Biosciences for TSC22D1
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for TSC22D1
- Browse OriGene Inhibitory RNA Products For TSC22D1
- genomics-online: shRNA clones - Search results for available TSC22D1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
Clone Products
-
OriGene ORF clones in human for TSC22D1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for TSC22D1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for TSC22D1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TSC22D1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available TSC22D1 gene related products
- orf clones - Search results for available TSC22D1 gene related products
- Applied Biological Materials Clones for TSC22D1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for TSC22D1
-
ViGene Biosciences adenoviral particle packaged cDNA for TSC22D1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for TSC22D1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TSC22D1 Gene
Localization for TSC22D1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TSC22D1 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| extracellular | 2 |
- Nuclear bodies (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | -- |
| GO:0005737 | cytoplasm | IBA | -- |
Pathways & Interactions for TSC22D1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Development_TGF-beta receptor signaling | ||
| 2 | Ectoderm Differentiation | ||
Pathways by source for TSC22D1 Gene
1 BioSystems pathway for TSC22D1 Gene
1 GeneGo (Thomson Reuters) pathway for TSC22D1 Gene
Interacting Proteins for TSC22D1 Gene
Selected Interacting proteins:
ENSP00000397435
Q15714-T22D1_HUMAN
for TSC22D1 Gene via
STRING
MINT
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription by RNA polymerase II | TAS | 9022669 |
No data available for SIGNOR curated interactions for TSC22D1 Gene
Transcripts for TSC22D1 Gene
mRNA/cDNA for TSC22D1 Gene
- (8) REFSEQ mRNAs :
- (22) Additional mRNA sequences :
- (1195) Selected AceView cDNA sequences:
- (13) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TSC22D1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for TSC22D1
- genomics-online: gRNA clones - Search results for available TSC22D1 gene related products
- Applied Biological Materials CRISPR for TSC22D1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TSC22D1
- GenScript: Design CRISPR guide RNA sequences for TSC22D1
miRNA Products
- Search ViGene Biosciences for TSC22D1
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for TSC22D1
- Browse OriGene Inhibitory RNA Products For TSC22D1
- genomics-online: shRNA clones - Search results for available TSC22D1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
Clone Products
-
OriGene ORF clones in human for TSC22D1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for TSC22D1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for TSC22D1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TSC22D1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available TSC22D1 gene related products
- orf clones - Search results for available TSC22D1 gene related products
- Applied Biological Materials Clones for TSC22D1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | · | 11c | · | 11d | · | 11e | · | 11f | ^ | 12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||
| SP12: | - |
Expression for TSC22D1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Kidney (Urinary System)
- S-shaped Body Cells S-shaped Body
- S-shaped Body
- Metanephros
- Neural Tube (Nervous System)
-
Liver (Hepatobiliary System)
- Perivenous Hepatocytes Liver Lobule
- Lung (Respiratory System)
- Eye (Sensory Organs)
This gene is overexpressed in Brain (11.8) and Uterus (6.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TSC22D1 Gene
NURSA nuclear receptor signaling pathways regulating expression of TSC22D1 Gene:
TSC22D1SOURCE GeneReport for Unigene cluster for TSC22D1 Gene:
Hs.436383mRNA Expression by UniProt/SwissProt for TSC22D1 Gene:
Q15714-T22D1_HUMAN
Tissue specificity:
Widely expressed in fetal and adult tissues.
Evidence on tissue expression from TISSUES for TSC22D1 Gene
- Nervous system(5)
- Lung(4.9)
- Intestine(4.8)
- Kidney(4.7)
- Pancreas(4.2)
- Eye(3.4)
- Stomach(3.3)
- Skin(3.1)
- Heart(2.8)
- Gall bladder(2.2)
- Adrenal gland(2)
- Muscle(2)
- Thyroid gland(2)
Primer Products
-
OriGene qPCR primer pairs for TSC22D1
-
OriGene qPCR primer pairs and template standards for TSC22D1
- genomics-online: primer clones - Search results for available TSC22D1 gene related products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TSC22D1 Gene
Orthologs for TSC22D1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TSC22D1 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | TSC22D1 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Tsc22d1 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Tsc22d1 33 |
|
||
| cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToMany | |
| TSC22D1 34 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | TSC22D1 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | TSC22D1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TSC22D1 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | TSC22D1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | tsc22d1 33 |
|
||
| Str.1572 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.8414 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | TSC22D1 (1 of 2) 34 |
|
OneToMany | |
| tsc22d1 34 |
|
OneToMany | |||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.9702 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | bun 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | C30G4.7 34 |
|
ManyToMany | |
| T18D3.7 34 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
ManyToMany |
- Species where no ortholog for TSC22D1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for TSC22D1 Gene
(3) SIMAP similar genes for TSC22D1 Gene using alignment to 4 proteins:
Variants for TSC22D1 Gene
| SNP ID | Clin | Chr 13 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000050699 | -- | 44,515,828(-) | G/A | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant | |
| rs1000073894 | -- | 44,576,964(-) | A/C | upstream_transcript_variant | |
| rs1000078305 | -- | 44,483,705(-) | C/T | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant | |
| rs1000078660 | -- | 44,518,775(-) | T/C | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant | |
| rs1000082332 | -- | 44,559,366(-) | T/C | genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv23675 | CNV | loss | 19812545 |
| esv2661792 | CNV | deletion | 23128226 |
| esv2669361 | CNV | deletion | 23128226 |
| esv2677067 | CNV | deletion | 23128226 |
| esv2747332 | CNV | deletion | 23290073 |
| esv3309377 | CNV | mobile element insertion | 20981092 |
| esv3433809 | CNV | insertion | 20981092 |
| esv3550396 | CNV | deletion | 23714750 |
| esv3631934 | CNV | loss | 21293372 |
| esv3631936 | CNV | loss | 21293372 |
| esv3631937 | CNV | loss | 21293372 |
| nsv1124673 | CNV | duplication | 24896259 |
| nsv561575 | CNV | loss | 21841781 |
| nsv958104 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
3.14% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.22;
62.18% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TSC22D1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TSC22D1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TSC22D1 Gene
Disorders for TSC22D1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| salivary gland cancer |
|
|
| brain sarcoma |
|
|
Search TSC22D1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TSC22D1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for TSC22D1 Gene
Publications for TSC22D1 Gene
- Cloning of the human homologue of the TGF beta-stimulated clone 22 gene. (PMID: 8651929) Jay P … Berta P (Biochemical and biophysical research communications 1996) 2 3 4 22 58
- Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter. (PMID: 9022669) Ohta S … Nagata K (European journal of biochemistry 1996) 2 3 4 22 58
- TGF-beta1 and TSC-22 gene polymorphisms and susceptibility to microvascular complications in type 2 diabetes. (PMID: 17622752) Buraczynska M … Ksiazek A (Nephron. Physiology 2007) 3 22 44 58
- Expression and cellular localization of TSC-22 in normal salivary glands and salivary gland tumors: implications for tumor cell differentiation. (PMID: 18288391) Doi Y … Imai Y (Oncology reports 2008) 3 22 58
- Interaction between fortilin and transforming growth factor-beta stimulated clone-22 (TSC-22) prevents apoptosis via the destabilization of TSC-22. (PMID: 18325344) Lee JH … Chun T (FEBS letters 2008) 3 22 58
Products for TSC22D1 Gene
- R&D Systems Antibodies for TSC22D1 (TSC22)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for TSC22D1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TSC22D1
- Search Origene for MassSpec and Protein Over-expression Lysates for TSC22D1
- Origene Custom Protein Services for TSC22D1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TSC22D1
- Browse OriGene Inhibitory RNA Products For TSC22D1
- OriGene qPCR primer pairs and template standards for TSC22D1
- OriGene qPCR primer pairs for TSC22D1
- OriGene CRISPR knockouts for TSC22D1
- OriGene ORF clones in human for TSC22D1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TSC22D1
- GenScript: Next-day shipping of latest version cDNA ORF clones for TSC22D1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for TSC22D1
- GenScript Custom Assay Services for TSC22D1
- GenScript Custom overexpressing Cell Line Services for TSC22D1
- GenScript: Design CRISPR guide RNA sequences for TSC22D1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for TSC22D1
- Sino Biological Human cDNA Clone for TSC22D1
- Sino Biological Recombinant Proteins for TSC22D1
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for TSC22D1
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for TSC22D1
- Novus Biologicals lysates and proteins for TSC22D1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for TSC22D1
- Abcam proteins for TSC22D1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Cloud-Clone Corp. Antibodies for TSC22D1
- Cloud-Clone Corp. Proteins for TSC22D1
- Cloud-Clone Corp. Assay Kits for TSC22D1
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for TSC22D1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for TSC22D1
- VectorBuilder custom plasmid, inducible vectors for TSC22D1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TSC22D1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 78 available TSC22D1 Antibodies ranked by validation data
- Compare Top TSC22D1 Antibodies
- antibodies-online: Search results for 9 available TSC22D1 Elisa Kits ranked by validation data
- Compare Top TSC22D1 Elisa Kits
- Quality Products:
- antibodies-online: Search results for 8 available TSC22D1 Proteins ranked by validation data
- Compare Top TSC22D1 Proteins
- Quality Products:
- Search GeneTex for Antibodies for TSC22D1
- Search GeneTex for Proteins for TSC22D1
- ViGene Biosciences adenoviral particle packaged cDNA for TSC22D1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TSC22D1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
- Search ViGene Biosciences for TSC22D1
- Santa Cruz Biotechnology (SCBT) Antibodies for TSC22D1
- Search Santa Cruz Biotechnology (SCBT) for TSC22D1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TSC22D1
- Horizon Cell Lines for TSC22D1
- genomics-online: cdna clones - Search results for available TSC22D1 gene related products
- orf clones - Search results for available TSC22D1 gene related products
- genomics-online: gRNA clones - Search results for available TSC22D1 gene related products
- genomics-online: primer clones - Search results for available TSC22D1 gene related products
- genomics-online: shRNA clones - Search results for available TSC22D1 gene related products
Sources for TSC22D1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew