Aliases for TSC22D1 Gene
Aliases for TSC22D1 Gene
External Ids for TSC22D1 Gene
- HGNC: 16826
- Entrez Gene: 8848
- Ensembl: ENSG00000102804
- OMIM: 607715
- UniProtKB: Q15714
Previous HGNC Symbols for TSC22D1 Gene
- TGFB1I4
Previous GeneCards Identifiers for TSC22D1 Gene
- GC13M043906
- GC13M045007
- GC13M025809
Summaries for TSC22D1 Gene
-
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for TSC22D1 Gene
TSC22D1 (TSC22 Domain Family Member 1) is a Protein Coding gene. Diseases associated with TSC22D1 include Salivary Gland Cancer and Brain Sarcoma. Among its related pathways are Development_TGF-beta receptor signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is TSC22D2.
UniProtKB/Swiss-Prot for TSC22D1 Gene
-
Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSC22D1 Gene
Genomics for TSC22D1 Gene
Regulatory Elements for TSC22D1 Gene
Enhancers for TSC22D1 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around TSC22D1 on UCSC Golden Path with GeneCards custom track
Promoters for TSC22D1 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around TSC22D1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for TSC22D1 Gene
- Chromosome:
- 13
- Start:
- 44,432,143 bp from pter
- End:
- 44,577,147 bp from pter
- Size:
- 145,005 bases
- Orientation:
- Minus strand
Genomic View for TSC22D1 Gene
Genes around TSC22D1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q14.11 by Ensembl
- 13q14 by Entrez Gene
- 13q14 by HGNC
TSC22D1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TSC22D1 Gene
Proteins for TSC22D1 Gene
-
Protein details for TSC22D1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q15714-T22D1_HUMAN
- Recommended name:
- TSC22 domain family protein 1
- Protein Accession:
- Q15714
- B3KRL7
- B9EGI0
- O00666
- Q6AHX5
- Q6IBU1
- Q8NCN1
- Q96JS5
Protein attributes for TSC22D1 Gene
- Size:
- 1073 amino acids
- Molecular mass:
- 109677 Da
- Quaternary structure:
-
- Homodimer or heterodimer. Can form a heterodimer with TSC22D4.
- SequenceCaution:
-
- Sequence=BAC02703.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for TSC22D1 Gene
Post-translational modifications for TSC22D1 Gene
Other Protein References for TSC22D1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for TSC22D1 (TSC22)
- Novus Biologicals Antibodies for TSC22D1
- Abcam antibodies for "TSC22 domain family, member 4"
-
Cloud-Clone Corp. Antibodies for TSC22D1
- Invitrogen Antibodies for TSC22D1
- antibodies-online Antibodies for TSC22D1: See all 71
- Search GeneTex for Antibodies for TSC22D1
-
Santa Cruz Biotechnology (SCBT) Antibodies for TSC22D1
Protein Products
-
OriGene Purified Proteins for TSC22D1
- Search Origene for MassSpec and Protein Over-expression Lysates for TSC22D1
- Origene Custom Protein Services for TSC22D1
- Sino Biological Recombinant Proteins for TSC22D1
- Browse Sino Biological Cell Lysates
-
Cloud-Clone Corp. Proteins for TSC22D1
- antibodies-online Proteins for TSC22D1: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Proteins for TSC22D1
- Abcam proteins for "TSC22 domain family, member 4"
Assay Products
-
Cloud-Clone Corp Assay Kits for TSC22D1
- antibodies-online Kits for TSC22D1: See all 7
No data available for DME Specific Peptides for TSC22D1 Gene
Domains & Families for TSC22D1 Gene
Protein Domains for TSC22D1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TSC22D1 Gene
Graphical View of Domain Structure for InterPro Entry
Q15714- Family:
-
- Belongs to the TSC-22/Dip/Bun family.
No data available for Gene Families for TSC22D1 Gene
Function for TSC22D1 Gene
Molecular function for TSC22D1 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
- UniProtKB/Swiss-Prot Induction:
- In aortic endothelial cells, induced by cytokines, including TGFB1.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 18325344 |
Phenotypes for TSC22D1 Gene
- MGI mutant phenotypes for TSC22D1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TSC22D1:
Animal Models for TSC22D1 Gene
- MGI Knock Outs for TSC22D1:
-
- Tsc22d1 tm1Clgr
Animal Model Products
-
Taconic Biosciences Mouse Models for TSC22D1
-
ViGene Biosciences lentiviral particle packaged cDNA for TSC22D1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
- Search ViGene Biosciences for TSC22D1
CRISPR Products
-
OriGene CRISPR knockouts for TSC22D1
-
Santa Cruz Biotechnology (SCBT) CRISPR for TSC22D1
- GenScript: Design CRISPR guide RNA sequences for TSC22D1
miRNA for TSC22D1 Gene
- miRTarBase miRNAs that target TSC22D1
-
- hsa-mir-100-5p (MIRT048416)
- hsa-mir-9-3p (MIRT441494)
- hsa-mir-590-3p (MIRT441495)
- hsa-mir-6858-5p (MIRT486471)
- hsa-mir-4689 (MIRT486472)
- hsa-mir-4784 (MIRT486473)
- hsa-mir-3150b-3p (MIRT486474)
- hsa-mir-199b-5p (MIRT486475)
- hsa-mir-199a-5p (MIRT486476)
- hsa-mir-1825 (MIRT486477)
- hsa-mir-708-5p (MIRT486478)
- hsa-mir-3139 (MIRT486479)
- hsa-mir-28-5p (MIRT486480)
- hsa-mir-6758-5p (MIRT486481)
- hsa-mir-6856-5p (MIRT486482)
miRNA Products
- Search ViGene Biosciences for TSC22D1
Clone Products
- OriGene clones in human for TSC22D1
- OriGene ORF clones in human,mouse,rat for TSC22D1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for TSC22D1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for TSC22D1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for TSC22D1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TSC22D1 Gene
Localization for TSC22D1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TSC22D1 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
No data available for Gene Ontology (GO) - Cellular Components for TSC22D1 Gene
Pathways & Interactions for TSC22D1 Gene
More details on SuperPathways for TSC22D1| Superpath | Contained pathways | |
|---|---|---|
| 1 | Development_TGF-beta receptor signaling |
Pathways by source for TSC22D1 Gene
1 GeneGo (Thomson Reuters) pathway for TSC22D1 Gene
Interacting Proteins for TSC22D1 Gene
Selected Interacting proteins:
Q15714-T22D1_HUMAN
ENSP00000397435
for TSC22D1 Gene via
MINT
STRING
UniProtKB
I2D
No data available for SIGNOR curated interactions for TSC22D1 Gene
Transcripts for TSC22D1 Gene
mRNA/cDNA for TSC22D1 Gene
- (6) REFSEQ mRNAs :
- (22) Additional mRNA sequences :
- (1195) Selected AceView cDNA sequences:
- (13) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TSC22D1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for TSC22D1
-
Santa Cruz Biotechnology (SCBT) CRISPR for TSC22D1
- GenScript: Design CRISPR guide RNA sequences for TSC22D1
miRNA Products
- Search ViGene Biosciences for TSC22D1
Clone Products
- OriGene clones in human for TSC22D1
- OriGene ORF clones in human,mouse,rat for TSC22D1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for TSC22D1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | · | 11c | · | 11d | · | 11e | · | 11f | ^ | 12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||
| SP12: | - |
Expression for TSC22D1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Kidney (Urinary System)
- S-shaped Body Cells S-shaped Body
- S-shaped Body
- Metanephros
- Neural Tube (Nervous System)
-
Liver (Hepatobiliary System)
- Perivenous Hepatocytes Liver Lobule
- Lung (Respiratory System)
- Eye (Sensory Organs)
This gene is overexpressed in Brain (11.8) and Uterus (6.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for TSC22D1 Gene
SOURCE GeneReport for Unigene cluster for TSC22D1 Gene Hs.436383
mRNA Expression by UniProt/SwissProt for TSC22D1 Gene
Q15714-T22D1_HUMAN
Tissue specificity:
Widely expressed in fetal and adult tissues.
Primer Products
-
OriGene qPCR primer pairs and template standards for TSC22D1
-
OriGene qPCR primer pairs for TSC22D1
No data available for mRNA differential expression in normal tissues for TSC22D1 Gene
Orthologs for TSC22D1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | TSC22D1 35 |
|
||
| TSC22D1 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Tsc22d1 35 |
|
||
| Tsc22d1 16 |
|
||||
| Tsc22d1 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | TSC22D1 35 |
|
||
| TSC22D1 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Tsc22d1 35 |
|
||
| cow (Bos Taurus) |
Mammalia | -- 36 |
|
OneToMany | |
| TSC22D1 36 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | TSC22D1 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | TSC22D1 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TSC22D1 35 |
|
||
| TSC22D1 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | TSC22D1 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.1572 35 |
|
||
| tsc22d1 35 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.8414 35 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.9702 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | tsc22d1 36 |
|
OneToMany | |
| TSC22D1 (1 of 2) 36 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | bun 36 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | C30G4.7 36 |
|
ManyToMany | |
| T18D3.7 36 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
ManyToMany |
- Species with no ortholog for TSC22D1:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for TSC22D1 Gene
(3) SIMAP similar genes for TSC22D1 Gene using alignment to 4 proteins:
Variants for TSC22D1 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_057311 | - | ||||
| rs11692 | -- | 44,433,561(-) | TGTTG(C/G)ACTTG | utr-variant-3-prime | |
| rs12044 | -- | 44,433,760(-) | GCTGC(C/T)GAATA | utr-variant-3-prime | |
| rs15121 | -- | 44,433,734(-) | TTGTT(C/G)ACTGA | utr-variant-3-prime | |
| rs928708 | -- | 44,511,086(+) | GACCA(G/T)CCTGG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2677067 | CNV | Deletion | 23128226 |
| esv2747332 | CNV | Deletion | 23290073 |
| esv23675 | CNV | Loss | 19812545 |
| esv271017 | CNV | Insertion | 20981092 |
| esv273649 | CNV | Insertion | 20981092 |
| esv2669361 | CNV | Deletion | 23128226 |
| esv2661792 | CNV | Deletion | 23128226 |
Residual Variation Intolerance Score:
3.14% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.22;
62.18% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TSC22D1 Gene
Disorders for TSC22D1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| salivary gland cancer |
|
|
| brain sarcoma |
|
|
Search TSC22D1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for TSC22D1
No data available for UniProtKB/Swiss-Prot and Genatlas for TSC22D1 Gene
Publications for TSC22D1 Gene
- Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter. (PMID: 9022669) Ohta S. … Nagata K. (Eur. J. Biochem. 1996) 2 3 4 23 67
- Cloning of the human homologue of the TGF beta-stimulated clone 22 gene. (PMID: 8651929) Jay P. … Berta P. (Biochem. Biophys. Res. Commun. 1996) 2 3 23
- Expression and cellular localization of TSC-22 in normal salivary glands and salivary gland tumors: implications for tumor cell differentiation. (PMID: 18288391) Doi Y. … Imai Y. (Oncol. Rep. 2008) 3 23
- Interaction between fortilin and transforming growth factor-beta stimulated clone-22 (TSC-22) prevents apoptosis via the destabilization of TSC-22. (PMID: 18325344) Lee J.H. … Chun T. (FEBS Lett. 2008) 3 23
- TGF-beta1 and TSC-22 gene polymorphisms and susceptibility to microvascular complications in type 2 diabetes. (PMID: 17622752) Buraczynska M. … Ksiazek A. (Nephron Physiol 2007) 3 23
Products for TSC22D1 Gene
- R&D Systems Antibodies for TSC22D1 (TSC22)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- Browse ELISAs
- Browse Activity Assays
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- Browse Cell Selection and Detection Kits
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- Browse Immunoprecipitation Assays
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- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for TSC22D1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TSC22D1
- Search Origene for MassSpec and Protein Over-expression Lysates for TSC22D1
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- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for TSC22D1
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- OriGene qPCR primer pairs for TSC22D1
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- OriGene CRISPR knockouts for TSC22D1
- OriGene clones in human for TSC22D1
- OriGene ORF clones in human,mouse,rat for TSC22D1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for TSC22D1
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- GenScript: Design CRISPR guide RNA sequences for TSC22D1
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- GenScript Custom Peptide Services for TSC22D1
- Novus Biologicals Antibodies for TSC22D1
- Novus Biologicals proteins and lysates for TSC22D1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for "TSC22 domain family, member 4"
- Abcam proteins for "TSC22 domain family, member 4"
- Search for Assays for TSC22D1 at Abcam
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- Search knockout validated antibodies
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- Cloud-Clone Corp. Antibodies for TSC22D1
- Cloud-Clone Corp. Proteins for TSC22D1
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- Taconic Biosciences Mouse Models for TSC22D1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for TSC22D1: See all 71
- antibodies-online Kits for TSC22D1: See all 7
- antibodies-online Proteins for TSC22D1: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for TSC22D1
- Search GeneTex for Proteins for TSC22D1
- ViGene Biosciences adenoviral particle packaged cDNA for TSC22D1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TSC22D1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TSC22D1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TSC22D1 gene
- Search ViGene Biosciences for TSC22D1
- Search ViGene Biosciences for TSC22D1
- Santa Cruz Biotechnology (SCBT) Antibodies for TSC22D1
- Search Santa Cruz Biotechnology (SCBT) for TSC22D1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TSC22D1
Sources for TSC22D1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
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