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Aliases for TRX-CAT2-1 Gene

Subcategory (RNA class) for TRX-CAT2-1 Gene

tRNA

Quality Score for this RNA gene is

2

Aliases for TRX-CAT2-1 Gene

  • Transfer RNA-IMet (CAT) 2-1 2 3
  • Transfer RNA Methionine Initiator 1 (Anticodon CAU) 2 3
  • Transfer RNA Initiator Methionine (CAT) 2-1 2 3
  • Transfer RNA Methionine 2 (Anticodon CAU) 2 3
  • TRNA Methionine Initiator 1 3
  • TRNA-IMet-CAT-2-1 3
  • TRNAMI2 3
  • TRNAMI1 3
  • RNTMI2 3
  • TRNAM2 3
  • RNTMI 3
  • TRMI1 3
  • TRM1 3

External Ids for TRX-CAT2-1 Gene

ORGUL Members for TRX-CAT2-1 Gene

Previous HGNC Symbols for TRX-CAT2-1 Gene

  • TRM1
  • TRMI1
  • TRNAMI1
  • TRNAM2

Previous GeneCards Identifiers for TRX-CAT2-1 Gene

  • GC06P027781
  • GC06P027785

Summaries for TRX-CAT2-1 Gene

Entrez Gene Summary for TRX-CAT2-1 Gene

  • Santos and Zasloff (1981) [PubMed 6261953] identified 12 initiator methionine tRNA genes, symbolized tRNA-i(met), in the haploid human genome. Zasloff et al. (1982) [PubMed 6923137] found a variant tRNA-i(met) with a G-to-T transversion in the highly conserved TCGA sequence in loop 4, a sequence position occupied exclusively by a purine (usually G) in almost 200 prokaryotic and eukaryotic tRNAs. One functional consequence of this base substitution is reduction in the rate of processing of the primary transcript of the gene. A second, demonstrated by microinjection into the germinal vesicle of the intact Xenopus laevis oocyte, is blockage of egress from the nucleus. It has been estimated that the human haploid genome contains 1,000 to 2,000 tRNA genes and that there are 50 to 60 chromatographically distinct tRNA species. These observations suggest redundancy of some tRNA genes. The studies of initiator methionine tRNA genes bear out this suspicion.[supplied by OMIM, Sep 2009]

GeneCards Summary for TRX-CAT2-1 Gene

TRX-CAT2-1 (Transfer RNA-IMet (CAT) 2-1) is an RNA Gene, and is affiliated with the tRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRX-CAT2-1 Gene

Genomics for TRX-CAT2-1 Gene

Genomic Location for TRX-CAT2-1 Gene

Chromosome:
6
Start:
27,777,885 bp from pter
End:
27,777,956 bp from pter
Size:
72 bases
Orientation:
Plus strand

Genomic View for TRX-CAT2-1 Gene

Genes around TRX-CAT2-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRX-CAT2-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRX-CAT2-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRX-CAT2-1 Gene

No data available for Regulatory Elements for TRX-CAT2-1 Gene

Proteins for TRX-CAT2-1 Gene

Post-translational modifications for TRX-CAT2-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRX-CAT2-1 Gene

Domains & Families for TRX-CAT2-1 Gene

Gene Families for TRX-CAT2-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRX-CAT2-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRX-CAT2-1 Gene

Function for TRX-CAT2-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRX-CAT2-1 Gene

Localization for TRX-CAT2-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRX-CAT2-1 Gene

Pathways & Interactions for TRX-CAT2-1 Gene

SuperPathways for TRX-CAT2-1 Gene

No Data Available

Interacting Proteins for TRX-CAT2-1 Gene

Gene Ontology (GO) - Biological Process for TRX-CAT2-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRX-CAT2-1 Gene

Drugs & Compounds for TRX-CAT2-1 Gene

No Compound Related Data Available

Transcripts for TRX-CAT2-1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRX-CAT2-1 Gene

No ASD Table

Relevant External Links for TRX-CAT2-1 Gene

GeneLoc Exon Structure for
TRX-CAT2-1
ECgene alternative splicing isoforms for
TRX-CAT2-1

No data available for mRNA/cDNA for TRX-CAT2-1 Gene

Expression for TRX-CAT2-1 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TRX-CAT2-1 Gene

Orthologs for TRX-CAT2-1 Gene

No data available for Orthologs and Evolution for TRX-CAT2-1 Gene

Paralogs for TRX-CAT2-1 Gene

No data available for Paralogs for TRX-CAT2-1 Gene

Variants for TRX-CAT2-1 Gene

Relevant External Links for TRX-CAT2-1 Gene

HapMap Linkage Disequilibrium report
TRX-CAT2-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRX-CAT2-1 Gene

Disorders for TRX-CAT2-1 Gene

No disorders were found for TRX-CAT2-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRX-CAT2-1 Gene

Publications for TRX-CAT2-1 Gene

  1. Comparative analysis of human chromosomal segments bearing nonallelic dispersed tRNAimet genes. (PMID: 6261953) Santos T. … Zasloff M. (Cell 1981) 2 3 67
  2. GtRNAdb: a database of transfer RNA genes detected in genomic sequence. (PMID: 18984615) Chan P.P. … Lowe T.M. (Nucleic Acids Res. 2009) 3
  3. Two nonallelic tRNAiMet genes are located in the p23 leads to q12 region of human chromosome 6. (PMID: 6308668) Naylor S.L. … Zasloff M. (Proc. Natl. Acad. Sci. U.S.A. 1983) 3
  4. Impaired nuclear transport of a human variant tRNAiMet. (PMID: 6923137) Zasloff M. … Santos T. (Nature 1982) 3

Products for TRX-CAT2-1 Gene

Sources for TRX-CAT2-1 Gene

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