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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRUB1 Gene

protein-coding   GIFtS: 55
GCID: GC10P116687

TruB Pseudouridine (Psi) Synthase Family Member 1

(Previous name: TruB pseudouridine (psi) synthase homolog 1 (E. coli))
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
TruB Pseudouridine (Psi) Synthase Family Member 11 2     TruB Pseudouridine (Psi) Synthase Homolog 12
PUS42 3 5     EC 5.4.99.-3
TruB Pseudouridine (Psi) Synthase Homolog 1 (E. Coli)1     EC 5.4.998
Probable TRNA Pseudouridine Synthase 12     

External Ids:    HGNC: 160601   Entrez Gene: 1429402   Ensembl: ENSG000001658327   OMIM: 6107265   UniProtKB: Q8WWH53   

Export aliases for TRUB1 gene to outside databases

Previous GC identifers: GC10P115616 GC10P115941 GC10P116829 GC10P116362 GC10P110325


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRUB1 Gene:
Pseudouridine is an abundant component of rRNAs and tRNAs and is enzymatically generated by isomerization of
uridine by pseudouridine synthase (Zucchini et al., 2003 (PubMed 12736709)).(supplied by OMIM, Mar 2008)

GeneCards Summary for TRUB1 Gene: 
TRUB1 (TruB pseudouridine (psi) synthase family member 1) is a protein-coding gene. Diseases associated with TRUB1 include dyskeratosis congenita-1, and dyskeratosis congenita. GO annotations related to this gene include pseudouridine synthase activity and RNA binding. An important paralog of this gene is TRUB2.

UniProtKB/Swiss-Prot: TRUB1_HUMAN, Q8WWH5
Function: May be responsible for synthesis of pseudouridine from uracil in transfer RNAs (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.2  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRUB1 gene promoter:
         COUP-TF1   RP58   COUP   HNF-4alpha2   Nkx2-5   HNF-4alpha1   PPAR-gamma1   COUP-TF   STAT3   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRUB1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRUB1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRUB1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.3   Ensembl cytogenetic band:  10q25.3   HGNC cytogenetic band: 10q25.3

TRUB1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRUB1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P116687:  view genomic region     (about GC identifiers)

Start:
116,697,952 bp from pter      End:
116,737,439 bp from pter
Size:
39,488 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TRUB1_HUMAN, Q8WWH5 (See protein sequence)
Recommended Name: Probable tRNA pseudouridine synthase 1  
Size: 349 amino acids; 37253 Da
Secondary accessions: B2R716 Q53ES2

Explore the universe of human proteins at neXtProt for TRUB1: NX_Q8WWH5

Explore proteomics data for TRUB1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WWH5

  • 4/5 DME Specific Peptides for TRUB1 (Q8WWH5) (see all 5)
     SALKKDG  KPKGPTS  GHGGTLD  LLNRLKEK 

    TRUB1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRUB1 Protein Expression
    REFSEQ proteins: NP_631908.1  
    ENSEMBL proteins: 
     ENSP00000298746  

    Human Recombinant Protein Products for TRUB1: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR020103 PsdUridine_synth_cat_dom
     IPR014780 tRNA_psdUridine_synth_TruB
     IPR002501 PsdUridine_synth

    Graphical View of Domain Structure for InterPro Entry Q8WWH5

    ProtoNet protein and cluster: Q8WWH5

    1 Blocks protein domain: IPB002501 Pseudouridylate synthase TruB

    UniProtKB/Swiss-Prot: TRUB1_HUMAN, Q8WWH5
    Similarity: Belongs to the pseudouridine synthase TruB family


    TRUB1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRUB1_HUMAN, Q8WWH5
    Function: May be responsible for synthesis of pseudouridine from uracil in transfer RNAs (By similarity)
    Catalytic activity: tRNA uridine = tRNA pseudouridine

         Enzyme Numbers (IUBMB): EC 5.4.992 EC 5.4.99.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0009982pseudouridine synthase activity IEA--
         
    TRUB1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRUB1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TRUB1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRUB1 
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    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate TRUB1 (see all 11):
    hsa-miR-22 hsa-miR-548am hsa-miR-7-2* hsa-miR-374b hsa-miR-3617 hsa-miR-374a hsa-miR-548aa hsa-miR-641
    SwitchGear 3'UTR luciferase reporter plasmidTRUB1 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRUB1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/800 Interacting proteins for TRUB1 (Q8WWH52, 3 ENSP000002987464) via UniProtKB, MINT, STRING, and/or I2D (see all 800)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EEF1A1P681042, 3MINT-7945693 MINT-7947479 I2D: score=1 
    RPL19P840982, 3MINT-7945693 I2D: score=2 
    RPS13P622772, 3MINT-7947479 I2D: score=1 
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    SNW1Q135732, ENSP000002615314MINT-7945693 MINT-7947479 STRING: ENSP00000261531
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001522pseudouridine synthesis IEA--
    GO:0006396RNA processing ----
    GO:0008033tRNA processing IEA--
    GO:0009451RNA modification ----

    TRUB1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRUB1

    1 HMDB Compound for TRUB1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Pseudouridine5-(b-D-Ribofuranosyl)uracil (see all 12)1445-07-4--

    Search CenterWatch for drugs/clinical trials and news about TRUB1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRUB1 gene: 
    NM_139169.4  

    Unigene Cluster for TRUB1:

    TruB pseudouridine (psi) synthase homolog 1 (E. coli)
    Hs.21187  [show with all ESTs]
    Unigene Representative Sequence: BC030601
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000298746(uc010qsl.2 uc001lcd.3) ENST00000485065
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate TRUB1 (see all 11):
    hsa-miR-22 hsa-miR-548am hsa-miR-7-2* hsa-miR-374b hsa-miR-3617 hsa-miR-374a hsa-miR-548aa hsa-miR-641
    SwitchGear 3'UTR luciferase reporter plasmidTRUB1 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRUB1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRUB1

    Additional mRNA sequence: 

    AF448144.1 AK026721.1 AK125554.1 AK223567.1 AK302800.1 AK312805.1 BC030601.2 BX648443.1 
    BX648479.1 BX648709.1 

    7 DOTS entries:

    DT.100718783  DT.121265035  DT.97809515  DT.101982095  DT.215681  DT.100751204  DT.97815200 

    24/111 AceView cDNA sequences (see all 111):

    AI763171 AI299932 Z39556 AA781326 AA806991 Z45109 AA494490 BX955486 
    BX091117 AI368111 AF448144 AI208778 AA927829 AW193222 AA243303 AA984328 
    CA429869 F04016 BX494667 BX648479 N23387 BQ961439 BM970359 BX648443 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TRUB1    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8
    SP1:                                            -                                 
    SP2:                          -                 -                                 
    SP3:                                      -     -                                 
    SP4:                                                                              


    ECgene alternative splicing isoforms for TRUB1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRUB1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGCATTAAC
    TRUB1 Expression
    About this image


    See TRUB1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRUB1

    SOURCE GeneReport for Unigene cluster: Hs.21187

    UniProtKB/Swiss-Prot: TRUB1_HUMAN, Q8WWH5
    Tissue specificity: Highly expressed in heart, skeletal muscle and liver. Expressed at lower levels in lung, small
    intestine, kidney and spleen

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TRUB1 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trub11 , 5 TruB pseudouridine (psi) synthase homolog 1 (E. coli)1, 5 81.15(n)1
    83.04(a)1
      19 (52.25 cM)5
    721331  NM_028115.31  NP_082391.11 
     574529065 
    chicken
    (Gallus gallus)
    Aves TRUB11 TruB pseudouridine (psi) synthase homolog 1 (E. coli) 76.54(n)
    75.56(a)
      423914  XM_421776.3  XP_421776.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRUB16
    Uncharacterized protein
    68(a)
    1 ↔ 1
    GL343206.1(3674344-3727762)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.154322 Xenopus laevis transcribed sequence with weak similarity more 73.47(n)    BU901199.1 
    zebrafish
    (Danio rerio)
    Actinopterygii trub11 TruB pseudouridine (psi) synthase homolog 1 (E. coli) 64.25(n)
    67.18(a)
      556642  NM_001128687.1  NP_001122159.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PUS4(YNL292W)4 Pseudouridine synthase, catalyzes only the formation more   --   14(82806-84017) 855424  NP_014107.1 


    ENSEMBL Gene Tree for TRUB1 (if available)
    TreeFam Gene Tree for TRUB1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRUB1 gene
    TRUB22  

    TRUB1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/808 SNPs in TRUB1 are shown (see all 808)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs78949761,2
    C--116695983(+) aacccC/Tgtccc 1 -- us2k10--------
    rs1453909961,2
    C--116696028(+) ACATG-/CCT   
       GTAAT
    CCCAC
    1 -- us2k10--------
    rs1900736411,2
    --116696051(+) CAGGAG/TTCTGA 1 -- us2k10--------
    rs1388884371,2
    --116696086(+) GAGGCA/GGAGGT 1 -- us2k10--------
    rs1821235831,2
    --116696342(+) ACATGA/TATTGG 1 -- us2k10--------
    rs1848572281,2
    --116696360(+) AAAACC/GTGTGA 1 -- us2k10--------
    rs1425283891,2
    --116696443(+) AATGCC/TGATAT 1 -- us2k10--------
    rs78985311,2
    C,F,H--116696450(+) ATATAA/GTAGCA 1 -- us2k18Minor allele frequency- G:0.12NS EA WA CSA NA 660
    rs792089111,2
    --116696550(+) CTCTGC/GTCCTA 1 -- us2k10--------
    rs1892715921,2
    --116696665(+) TTGCTA/GATGTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TRUB1 (116697952 - 116737439 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TRUB1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2666688CNV Deletion23128226
    nsv831997CNV Gain17160897
    nsv831996CNV Gain17160897
    nsv7211OTHER Inversion18451855

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610726    OMIM disorders: --

    5 diseases for TRUB1:    About MalaCards
    dyskeratosis congenita-1    dyskeratosis congenita    pneumonia    tuberculosis
    alzheimer's disease

    1 disease from the University of Copenhagen DISEASES database for TRUB1:
    Dyskeratosis congenita

    TRUB1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): TRUB1
    Human Genome Epidemiology (HuGE) Navigator: TRUB1 (1 document)

    Export disorders for TRUB1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRUB1 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with TRUB1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human TruB family of pseudouridine synthase genes, including the Dyskeratosis Congenita 1 gene and the novel member TRUB1. (PubMed id 12736709)1, 2, 3, 9 Zucchini C.... Valvassori L. (2003)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    10. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 142940 HGNC: 16060 AceView: TRUB1 Ensembl:ENSG00000165832 euGenes: HUgn142940
    ECgene: TRUB1 H-InvDB: TRUB1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRUB1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRUB1 gene:
    Search GeneIP for patents involving TRUB1

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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