Aliases for TRPV5 Gene
Aliases for TRPV5 Gene
External Ids for TRPV5 Gene
- HGNC: 3145
- Entrez Gene: 56302
- Ensembl: ENSG00000127412
- OMIM: 606679
- UniProtKB: Q9NQA5
Previous HGNC Symbols for TRPV5 Gene
- ECAC1
Previous GeneCards Identifiers for TRPV5 Gene
- GC07M140931
- GC07M141999
- GC07M142076
- GC07M142122
- GC07M142315
- GC07M142606
- GC07M136943
Summaries for TRPV5 Gene
-
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]
GeneCards Summary for TRPV5 Gene
TRPV5 (Transient Receptor Potential Cation Channel Subfamily V Member 5) is a Protein Coding gene. Diseases associated with TRPV5 include Hypervitaminosis D and Aromatase Deficiency. Among its related pathways are Osteoclast Signaling and Endocrine and other factor-regulated calcium reabsorption. Gene Ontology (GO) annotations related to this gene include calmodulin binding and calcium channel activity. An important paralog of this gene is TRPV6.
UniProtKB/Swiss-Prot for TRPV5 Gene
-
Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:11549322, PubMed:18768590). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity).
-
Vanilloids are a group of compounds, structurally related to capsaicin, thought to exert their actions via vanilloid receptors. The vanilloid receptor family (TRPV) is a member of the transient receptor potential (TRP) superfamily of ion channels, and have six members (TRPV1-6).
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRPV5 Gene
Genomics for TRPV5 Gene
GeneHancer (GH) Regulatory Elements for TRPV5 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH07I142933 | Promoter | 0.5 | EPDnew | 550.8 | +0.0 | 42 | 0.1 | TRPV5 TRPV6 | ||
GH07I142908 | Enhancer | 0.8 | Ensembl ENCODE | 12.2 | +24.1 | 24077 | 2.4 | CTCF RXRA MCM5 MNT ELF1 RAD21 CTBP1 ZNF316 IKZF1 ZNF143 | CASP2 KEL TRPV5 LLCFC1 LOC154761 EPHB6 TCAF2 RN7SL535P OR9P1P OR6V1 | |
GH07I142838 | Enhancer | 0.8 | ENCODE | 9.8 | +95.1 | 95144 | 0.2 | PKNOX1 TCF12 GATA2 ATF7 NFIC SMARCA4 MYNN IKZF1 ZNF24 KDM1A | KEL TRPV5 LLCFC1 EPHB6 TRBV30 | |
GH07I142805 | Enhancer | 1.6 | FANTOM5 Ensembl ENCODE dbSUPER | 4.5 | +125.1 | 125071 | 5.7 | HDGF PKNOX1 SMAD1 IRF4 NCOA2 TCF12 GATA2 ZNF143 ATF7 FOS | TRBV30 TRPV6 GSTK1 EPHB6 TCAF1P1 TRPV5 CASP2 GC07M142813 TRBC2 TRB | |
GH07I143126 | Enhancer | 0.7 | Ensembl ENCODE | 10.1 | -192.4 | -192393 | 0.4 | JUND GATA3 FOS GABPA | KEL LLCFC1 TRPV5 TMEM139 PIP OR6W1P |
- Top Transcription factor binding sites by QIAGEN in the TRPV5 gene promoter:
Regulatory Element Products
Genomic Locations for TRPV5 Gene
- chr7:142,908,101-142,933,808
- (GRCh38/hg38)
- Size:
- 25,708 bases
- Orientation:
- Minus strand
- chr7:142,605,267-142,630,905
- (GRCh37/hg19)
Genomic View for TRPV5 Gene
- Cytogenetic band:
-
- 7q34 by Ensembl
- 7q34 by Entrez Gene
- 7q34 by HGNC


RefSeq DNA sequence for TRPV5 Gene
Proteins for TRPV5 Gene
-
Protein details for TRPV5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NQA5-TRPV5_HUMAN
- Recommended name:
- Transient receptor potential cation channel subfamily V member 5
- Protein Accession:
- Q9NQA5
- A4D2H7
- E9PBZ6
- Q8N4C1
- Q8NDW5
- Q8NDX7
- Q8NDX8
- Q96PM6
Protein attributes for TRPV5 Gene
- Size:
- 729 amino acids
- Molecular mass:
- 82551 Da
- Quaternary structure:
-
- Homotetramer and probably heterotetramer with TRPV6. Interacts with TRPV6 (By similarity). Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with calmodulin. Interacts with BSPRY, which results in its inactivation.
Protein Expression for TRPV5 Gene
Post-translational modifications for TRPV5 Gene
- Glycosylated.
- Glycosylation at isoforms=2358
Other Protein References for TRPV5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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No data available for DME Specific Peptides for TRPV5 Gene
Domains & Families for TRPV5 Gene
Gene Families for TRPV5 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Transporters
- Voltage-gated ion channels
Protein Domains for TRPV5 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TRPV5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9NQA5UniProtKB/Swiss-Prot:
TRPV5_HUMAN :- Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.
- Family:
-
- Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.
Function for TRPV5 Gene
Molecular function for TRPV5 Gene
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Activated by WNK3.
- UniProtKB/Swiss-Prot Function:
- Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:11549322, PubMed:18768590). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity).
Phenotypes From GWAS Catalog for TRPV5 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005262 | calcium channel activity | TAS | -- |
GO:0005515 | protein binding | IPI | 16763551 |
GO:0005516 | calmodulin binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for TRPV5 Gene
- MGI mutant phenotypes for TRPV5:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for TRPV5:
-
- Increased vaccinia virus (VACV) infection
- Decreased hepcidin::fluc mRNA expression
- shRNA abundance <= 50%
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Decreased viability
- Decreased shRNA abundance (Z-score < -2)
- Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation
Animal Models for TRPV5 Gene
- MGI Knock Outs for TRPV5:
-
- Trpv5 tm1Bind
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-
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- Mammalian expression: PiggyBac
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- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TRPV5
-
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TRPV5 Gene
Localization for TRPV5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TRPV5 Gene
- Apical cell membrane; Multi-pass membrane protein. Note=Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity). The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3 (PubMed:18768590). {ECO:0000250 UniProtKB:P69744, ECO:0000269 PubMed:18768590}.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | TAS | -- |
GO:0005887 | integral component of plasma membrane | IDA | 15489237 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO:0016324 | apical plasma membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for TRPV5 Gene
Pathways & Interactions for TRPV5 Gene
Pathways by source for TRPV5 Gene
1 BioSystems pathway for TRPV5 Gene
4 Reactome pathways for TRPV5 Gene
1 KEGG pathway for TRPV5 Gene
1 Qiagen pathway for TRPV5 Gene
Interacting Proteins for TRPV5 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006810 | transport | IEA | -- |
GO:0006811 | ion transport | IEA | -- |
GO:0006816 | calcium ion transport | TAS | 15665527 |
GO:0034220 | ion transmembrane transport | IEA | -- |
GO:0035809 | regulation of urine volume | ISS | -- |
Drugs & Compounds for TRPV5 Gene
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Econazole | Approved | Pharma | Antagonist, Pore Blocker, inhibitor | 8 | ||
Miconazole | Approved, Investigational, Vet_approved | Pharma | Antagonist, Pore Blocker, inhibitor | 3838 | ||
calcium | Approved | Nutra | 0 | |||
Calcium Citrate | Approved | Pharma | Transporter, substrate | 0 | ||
Calcium Phosphate | Approved | Pharma | Transporter, substrate | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
(E)-Capsaicin |
|
404-86-4 |
|
|
(5) Tocris Compounds for TRPV5 Gene
Compound | Action | Cas Number |
---|---|---|
(E)-Capsaicin | Prototypic vanilloid receptor agonist | 404-86-4 |
Capsazepine | Vanilloid receptor antagonist; also activator of ENaCdelta | 138977-28-3 |
Olvanil | Potent vanilloid receptor agonist | 58493-49-5 |
Resiniferatoxin | Potent vanilloid receptor agonist | 57444-62-9 |
STEARDA | Endogenous lipid, active in vivo. Enhances effects of endovanilloids at TRPV1 receptors | 105955-10-0 |
(1) ApexBio Compounds for TRPV5 Gene
Compound | Action | Cas Number |
---|---|---|
HC-030031 | TRPA1 channel blocker,potent and selective | 349085-38-7 |
Transcripts for TRPV5 Gene
mRNA/cDNA for TRPV5 Gene
- (1) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (7) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TRPV5 Gene
CRISPR Products
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Clone Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TRPV5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for TRPV5
Expression for TRPV5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Distal Tubule Cells Distal Tubule
-
Epithelial Cells
- Distal Tubule Cells Distal Tubule
mRNA differential expression in normal tissues according to GTEx for TRPV5 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TRPV5 Gene
NURSA nuclear receptor signaling pathways regulating expression of TRPV5 Gene:
TRPV5SOURCE GeneReport for Unigene cluster for TRPV5 Gene:
Hs.283369mRNA Expression by UniProt/SwissProt for TRPV5 Gene:
Q9NQA5-TRPV5_HUMANEvidence on tissue expression from TISSUES for TRPV5 Gene
- Intestine(4.4)
- Kidney(2.7)
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No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TRPV5 Gene
Orthologs for TRPV5 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | TRPV5 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | TRPV5 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | TRPV5 33 34 |
|
||
mouse (Mus musculus) |
Mammalia | Trpv5 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Trpv5 33 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | TRPV5 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | TRPV5 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | -- 34 |
|
OneToMany | |
lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
ManyToMany | |
-- 34 |
|
ManyToMany | |||
zebrafish (Danio rerio) |
Actinopterygii | trpv6 34 |
|
OneToMany | |
fruit fly (Drosophila melanogaster) |
Insecta | nan 35 34 |
|
||
iav 34 |
|
ManyToMany | |||
worm (Caenorhabditis elegans) |
Secernentea | ocr-4 35 34 |
|
||
osm-9 35 34 |
|
||||
ocr-1 34 |
|
ManyToMany | |||
ocr-3 34 |
|
ManyToMany | |||
ocr-2 34 |
|
ManyToMany | |||
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
ManyToMany | |
-- 34 |
|
ManyToMany |
- Species where no ortholog for TRPV5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for TRPV5 Gene
Variants for TRPV5 Gene
SNP ID | Clin | Chr 07 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs202171798 | uncertain-significance, not provided | 142,925,616(-) | C/G/T | coding_sequence_variant, synonymous_variant | |
rs373756563 | uncertain-significance, not provided | 142,929,073(-) | C/T | coding_sequence_variant, missense_variant | |
rs377258108 | uncertain-significance, not provided | 142,933,427(-) | G/A/T | coding_sequence_variant, synonymous_variant | |
rs387907541 | uncertain-significance, not provided | 142,908,736(-) | C/T | coding_sequence_variant, synonymous_variant | |
rs387907542 | uncertain-significance, not provided | 142,925,685(-) | G/A | coding_sequence_variant, synonymous_variant |
Additional Variant Information for TRPV5 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRPV5 Gene
Disorders for TRPV5 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
hypervitaminosis d |
|
|
aromatase deficiency |
|
|
idiopathic hypercalciuria |
|
|
Additional Disease Information for TRPV5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for TRPV5 Gene
Publications for TRPV5 Gene
- Molecular cloning, tissue distribution, and chromosomal mapping of the human epithelial Ca2+ channel (ECAC1). (PMID: 10945469) Müller D … Bindels RJ (Genomics 2000) 2 3 4 22 58
- Structural conservation of the genes encoding CaT1, CaT2, and related cation channels. (PMID: 11549322) Peng JB … Hediger MA (Genomics 2001) 3 4 22 58
- Gene structure and chromosomal mapping of human epithelial calcium channel. (PMID: 10944439) Müller D … Bindels RJ (Biochemical and biophysical research communications 2000) 2 3 22 58
- Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium. (PMID: 20405023) Kennedy BG … Mangini NJ (Molecular vision 2010) 3 22 58
- High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PMID: 19453261) Yerges LM … MrOS Research Group (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009) 3 44 58
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 73 available TRPV5 Antibodies ranked by validation data
- Compare Top TRPV5 Antibodies
- antibodies-online: Search results for 1 available TRPV5 Elisa Kits ranked by validation data
- Compare Top TRPV5 Elisa Kits
- Quality Products:
- antibodies-online: Search results for 7 available TRPV5 Proteins ranked by validation data
- Compare Top TRPV5 Proteins
- Quality Products:
- Search GeneTex for Antibodies for TRPV5
- Search GeneTex for Proteins for TRPV5
- ViGene Biosciences adenoviral particle packaged cDNA for TRPV5 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TRPV5 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TRPV5 gene
- Search ViGene Biosciences for TRPV5
- Santa Cruz Biotechnology (SCBT) Antibodies for TRPV5
- Search Santa Cruz Biotechnology (SCBT) for TRPV5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TRPV5
- Horizon Cell Lines for TRPV5
- genomics-online: cdna clones - Search results for 85 available TRPV5 gene related products
- Overview of 85 available TRPV5 gene related products
- orf clones - Search results for 85 available TRPV5 gene related products
- Overview of 85 available TRPV5 gene related products
- genomics-online: gRNA clones - Search results for 85 available TRPV5 gene related products
- Overview of 85 available TRPV5 gene related products
- genomics-online: primer clones - Search results for 85 available TRPV5 gene related products
- Overview of 85 available TRPV5 gene related products
- genomics-online: shRNA clones - Search results for 85 available TRPV5 gene related products
- Overview of 85 available TRPV5 gene related products
Sources for TRPV5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew