Aliases for TRPM3 Gene
External Ids for TRPM3 Gene
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for TRPM3 Gene
TRPM3 (Transient Receptor Potential Cation Channel, Subfamily M, Member 3) is a Protein Coding gene. Diseases associated with TRPM3 include dentin sensitivity. Among its related pathways are CREB Pathway and Ion channel transport. GO annotations related to this gene include calcium channel activity and cation channel activity. An important paralog of this gene is TRPM1.
UniProtKB/Swiss-Prot for TRPM3 Gene
Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation.