Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TRPC2 Gene

Aliases for TRPC2 Gene

  • Transient Receptor Potential Cation Channel Subfamily C Member 2, Pseudogene 2 3 5
  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene 2
  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2 2

External Ids for TRPC2 Gene

Previous GeneCards Identifiers for TRPC2 Gene

  • GC11P004223
  • GC11U900038
  • GC11P003607
  • GC11P003601
  • GC11P003611
  • GC11P003385

Summaries for TRPC2 Gene

GeneCards Summary for TRPC2 Gene

TRPC2 (Transient Receptor Potential Cation Channel Subfamily C Member 2, Pseudogene) is a Pseudogene. Among its related pathways are CREB Pathway.

Gene Wiki entry for TRPC2 Gene

Additional gene information for TRPC2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRPC2 Gene

Genomics for TRPC2 Gene

GeneHancer (GH) Regulatory Elements for TRPC2 Gene

Promoters and enhancers for TRPC2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I003609 Enhancer 0.6 ENCODE 550.8 0.0 -35 0.2 CTCF ZNF654 TRIM22 REST RAD21 CC2D1A GATA3 KLF16 SMC3 ZNF143 TRPC2 ART1 ART5 LOC101927708 OR7E117P
GH11I002897 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 4.7 -710.8 -710799 2.6 SIN3A IRF4 GLIS2 FOS ATF7 RUNX3 DEK JUNB ZNF592 ATF4 SLC22A18 KCNQ1 TRPC2 SLC22A18AS CDKN1C
GH11I003626 Enhancer 0.6 Ensembl ENCODE 9.6 +16.7 16688 0.8 CTCF POLR2A NRF1 TRPC2 ART5 ART1
GH11I003627 Enhancer 0.4 ENCODE 8.9 +17.7 17718 1 FOSL1 GLIS1 TEAD2 ART5 TRPC2 ART1
GH11I003604 Enhancer 0.7 ENCODE 0.8 -4.4 -4368 2 NCOA3 HDAC1 MEIS2 ATF1 TEAD4 TAL1 HIC1 TCF12 CTBP1 GATA3 LOC101927708 OR7E117P TRPC2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRPC2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TRPC2 gene promoter:

Genomic Locations for TRPC2 Gene

Genomic Locations for TRPC2 Gene
27,659 bases
Plus strand

Genomic View for TRPC2 Gene

Genes around TRPC2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRPC2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRPC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRPC2 Gene

Proteins for TRPC2 Gene

Post-translational modifications for TRPC2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRPC2 Gene

Domains & Families for TRPC2 Gene

Gene Families for TRPC2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRPC2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRPC2 Gene

Function for TRPC2 Gene

Molecular function for TRPC2 Gene

GENATLAS Biochemistry:
transient receptor potential non voltage-channel 2,Drosophila store-operated channel (Soc) homolog,ubiquitous predominantly expressed in fetal brain,adult heart,brain,testis,ovaries,activated by calcium store depletion, component of the capacitative calcium entry,channels (homo or heterotetramer),may be a pseudogene

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRPC2 Gene

Localization for TRPC2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRPC2 Gene

Pathways & Interactions for TRPC2 Gene

SuperPathways for TRPC2 Gene

SuperPathway Contained pathways
1 CREB Pathway
genes like me logo Genes that share pathways with TRPC2: view

Pathways by source for TRPC2 Gene

1 Qiagen pathway for TRPC2 Gene

Interacting Proteins for TRPC2 Gene

Gene Ontology (GO) - Biological Process for TRPC2 Gene


No data available for SIGNOR curated interactions for TRPC2 Gene

Drugs & Compounds for TRPC2 Gene

No Compound Related Data Available

Transcripts for TRPC2 Gene

mRNA/cDNA for TRPC2 Gene

(8) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRPC2 Gene

No ASD Table

Relevant External Links for TRPC2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRPC2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRPC2 Gene

mRNA differential expression in normal tissues according to GTEx for TRPC2 Gene

This gene is overexpressed in Spleen (x4.1) and Whole Blood (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of TRPC2 Gene:


SOURCE GeneReport for Unigene cluster for TRPC2 Gene:

genes like me logo Genes that share expression patterns with TRPC2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRPC2 Gene

Orthologs for TRPC2 Gene

Evolution for TRPC2 Gene

Gene Tree for TRPC2 (if available)
Gene Tree for TRPC2 (if available)

No data available for Orthologs for TRPC2 Gene

Paralogs for TRPC2 Gene

No data available for Paralogs for TRPC2 Gene

Variants for TRPC2 Gene

Sequence variations from dbSNP and Humsavar for TRPC2 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000269661 -- 3,630,903(+) C/A/T intron_variant
rs1000364876 -- 3,629,846(+) AAAAAA/AAAA/AAAAAAA intron_variant
rs1000645690 -- 3,635,076(+) G/A non_coding_transcript_variant
rs1000688651 -- 3,624,585(+) C/T upstream_transcript_variant
rs1000738534 -- 3,629,708(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TRPC2 Gene

Variant ID Type Subtype PubMed ID
dgv186e199 CNV deletion 23128226
esv2658889 CNV deletion 23128226
esv2662660 CNV deletion 23128226
esv2675176 CNV deletion 23128226
esv2678063 CNV deletion 23128226
esv2744037 CNV deletion 23290073
esv2759796 CNV gain+loss 17122850
esv2760179 CNV loss 21179565
esv2760300 CNV gain 21179565
esv28322 CNV gain+loss 19812545
esv3547237 CNV deletion 23714750
esv3547238 CNV deletion 23714750
esv3625147 CNV gain 21293372
esv3625148 CNV gain 21293372
esv3625149 CNV loss 21293372
esv3625150 CNV loss 21293372
esv3625151 CNV loss 21293372
esv3625152 CNV loss 21293372
nsv1045810 CNV gain 25217958
nsv1046356 CNV gain 25217958
nsv1140120 CNV insertion 24896259
nsv1149571 CNV insertion 26484159
nsv428247 CNV loss 18775914
nsv467660 CNV gain 19166990
nsv509385 CNV insertion 20534489
nsv526441 CNV gain 19592680
nsv553140 CNV gain 21841781
nsv825717 CNV loss 20364138
nsv832051 CNV gain 17160897
nsv832052 CNV loss 17160897

Additional Variant Information for TRPC2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TRPC2 Gene

Disorders for TRPC2 Gene

Additional Disease Information for TRPC2

No disorders were found for TRPC2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRPC2 Gene

Publications for TRPC2 Gene

  1. TRPC2: molecular biology and functional importance. (PMID: 17217050) Yildirim E … Birnbaumer L (Handbook of experimental pharmacology 2007) 2 3 58
  2. International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. (PMID: 16382100) Clapham DE … Schultz G (Pharmacological reviews 2005) 2 3 58
  3. TRPC1, a human homolog of a Drosophila store-operated channel. (PMID: 7568191) Wes PD … Montell C (Proceedings of the National Academy of Sciences of the United States of America 1995) 2 3 58
  4. TRPC2. (PMID: 24756702) Miller BA (Handbook of experimental pharmacology 2014) 3 58
  5. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. (PMID: 20210993) Zhang ZD … Gerstein M (Genome biology 2010) 3 58

Products for TRPC2 Gene

Sources for TRPC2 Gene

Loading form....