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Aliases for TRPC2 Gene

Aliases for TRPC2 Gene

  • Transient Receptor Potential Cation Channel Subfamily C Member 2, Pseudogene 2 3 5
  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene 2
  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2 2

External Ids for TRPC2 Gene

Previous GeneCards Identifiers for TRPC2 Gene

  • GC11P004223
  • GC11U900038
  • GC11P003607
  • GC11P003601
  • GC11P003611
  • GC11P003385

Summaries for TRPC2 Gene

GeneCards Summary for TRPC2 Gene

TRPC2 (Transient Receptor Potential Cation Channel Subfamily C Member 2, Pseudogene) is a Pseudogene. Among its related pathways are CREB Pathway.

Gene Wiki entry for TRPC2 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRPC2 Gene

Genomics for TRPC2 Gene

Regulatory Elements for TRPC2 Gene

Enhancers for TRPC2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F003626 1 Ensembl ENCODE 9.6 +16.6 16600 1.0 CTCF RNF2 NRF1 TRPC2 ART5 ART1
GH11F003627 0.6 ENCODE 8.9 +17.7 17719 1.0 ATF1 PKNOX1 ARNT TAL1 ZBTB40 NCOR1 SMARCE1 L3MBTL2 MTA2 RNF2 ART5 TRPC2 ART1
GH11F002897 1.6 FANTOM5 Ensembl ENCODE 4.7 -710.8 -710801 3.0 TBP CBX3 RFX5 GLIS2 RCOR1 FOS CREM CEBPB USF2 JUNB SLC22A18 KCNQ1 TRPC2 CDKN1C
GH11F003614 1.1 FANTOM5 Ensembl ENCODE 0.8 +5.0 4979 1.8 BCOR SMARCE1 HDAC1 PKNOX1 ZMYM3 MAX ZIC2 RELA MBD2 GATA3 ART1 ART5 LOC101927708 NUP98 RHOG TRPC2
GH11F003609 0.6 ENCODE 0.8 0.0 -36 0.2 CTCF ZNF654 TRIM22 REST RAD21 GATA3 KLF16 ZNF143 SMC3 ART1 ART5 LOC101927708 TRPC2 OR7E117P
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TRPC2 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRPC2 Gene

Chromosome:
11
Start:
3,609,901 bp from pter
End:
3,637,559 bp from pter
Size:
27,659 bases
Orientation:
Plus strand

Genomic View for TRPC2 Gene

Genes around TRPC2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRPC2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRPC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRPC2 Gene

Proteins for TRPC2 Gene

Post-translational modifications for TRPC2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRPC2 Gene

Domains & Families for TRPC2 Gene

Gene Families for TRPC2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRPC2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRPC2 Gene

Function for TRPC2 Gene

Molecular function for TRPC2 Gene

GENATLAS Biochemistry:
transient receptor potential non voltage-channel 2,Drosophila store-operated channel (Soc) homolog,ubiquitous predominantly expressed in fetal brain,adult heart,brain,testis,ovaries,activated by calcium store depletion, component of the capacitative calcium entry,channels (homo or heterotetramer),may be a pseudogene

Animal Model Products

  • Taconic Biosciences Mouse Models for TRPC2

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRPC2 Gene

Localization for TRPC2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRPC2 Gene COMPARTMENTS Subcellular localization image for TRPC2 gene
Compartment Confidence
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TRPC2 Gene

Pathways & Interactions for TRPC2 Gene

SuperPathways for TRPC2 Gene

SuperPathway Contained pathways
1 CREB Pathway
genes like me logo Genes that share pathways with TRPC2: view

Pathways by source for TRPC2 Gene

1 Qiagen pathway for TRPC2 Gene

Interacting Proteins for TRPC2 Gene

Gene Ontology (GO) - Biological Process for TRPC2 Gene

None

No data available for SIGNOR curated interactions for TRPC2 Gene

Transcripts for TRPC2 Gene

mRNA/cDNA for TRPC2 Gene

(8) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRPC2 Gene

No ASD Table

Relevant External Links for TRPC2 Gene

GeneLoc Exon Structure for
TRPC2
ECgene alternative splicing isoforms for
TRPC2

Expression for TRPC2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRPC2 Gene

mRNA differential expression in normal tissues according to GTEx for TRPC2 Gene

This gene is overexpressed in Spleen (x4.1) and Whole Blood (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of TRPC2 Gene:

TRPC2

SOURCE GeneReport for Unigene cluster for TRPC2 Gene:

Hs.131910
genes like me logo Genes that share expression patterns with TRPC2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRPC2 Gene

Orthologs for TRPC2 Gene

Evolution for TRPC2 Gene

ENSEMBL:
Gene Tree for TRPC2 (if available)
TreeFam:
Gene Tree for TRPC2 (if available)

No data available for Orthologs for TRPC2 Gene

Paralogs for TRPC2 Gene

No data available for Paralogs for TRPC2 Gene

Variants for TRPC2 Gene

Sequence variations from dbSNP and Humsavar for TRPC2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1055470 -- 3,637,373(+) GGATT(C/G)TGAGG nc-transcript-variant
rs10742084 -- 3,626,064(+) GGCAC(A/G)GAGAA upstream-variant-2KB
rs10767372 -- 3,631,386(+) CAAGC(A/G)ATCCT intron-variant
rs10834658 -- 3,629,647(+) CACCA(C/G)GCCCA intron-variant
rs10834659 -- 3,629,654(+) CCCAG(C/G)TAATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRPC2 Gene

Variant ID Type Subtype PubMed ID
dgv186e199 CNV deletion 23128226
esv2658889 CNV deletion 23128226
esv2662660 CNV deletion 23128226
esv2675176 CNV deletion 23128226
esv2678063 CNV deletion 23128226
esv2744037 CNV deletion 23290073
esv2759796 CNV gain+loss 17122850
esv2760179 CNV loss 21179565
esv2760300 CNV gain 21179565
esv28322 CNV gain+loss 19812545
esv3547237 CNV deletion 23714750
esv3547238 CNV deletion 23714750
esv3625147 CNV gain 21293372
esv3625148 CNV gain 21293372
esv3625149 CNV loss 21293372
esv3625150 CNV loss 21293372
esv3625151 CNV loss 21293372
esv3625152 CNV loss 21293372
nsv1045810 CNV gain 25217958
nsv1046356 CNV gain 25217958
nsv1140120 CNV insertion 24896259
nsv1149571 CNV insertion 26484159
nsv428247 CNV loss 18775914
nsv467660 CNV gain 19166990
nsv509385 CNV insertion 20534489
nsv526441 CNV gain 19592680
nsv553140 CNV gain 21841781
nsv825717 CNV loss 20364138
nsv832051 CNV gain 17160897
nsv832052 CNV loss 17160897

Relevant External Links for TRPC2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRPC2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TRPC2 Gene

Disorders for TRPC2 Gene

Relevant External Links for TRPC2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRPC2

No disorders were found for TRPC2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRPC2 Gene

Publications for TRPC2 Gene

  1. TRPC2: molecular biology and functional importance. (PMID: 17217050) Yildirim E. … Birnbaumer L. (Handb Exp Pharmacol 2007) 2 3 64
  2. International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. (PMID: 16382100) Clapham D.E. … Schultz G. (Pharmacol. Rev. 2005) 2 3 64
  3. TRPC1, a human homolog of a Drosophila store-operated channel. (PMID: 7568191) Wes P.D. … Montell C. (Proc. Natl. Acad. Sci. U.S.A. 1995) 2 3 64
  4. TRPC2. (PMID: 24756702) Miller B.A. (Handb Exp Pharmacol 2014) 3 64
  5. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. (PMID: 20210993) Zhang Z.D. … Gerstein M. (Genome Biol. 2010) 3 64

Products for TRPC2 Gene

Sources for TRPC2 Gene

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