Aliases for TRPC1 Gene
External Ids for TRPC1 Gene
Previous GeneCards Identifiers for TRPC1 Gene
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for TRPC1 Gene
TRPC1 (Transient Receptor Potential Cation Channel Subfamily C Member 1) is a Protein Coding gene. Among its related pathways are Serotonergic synapse and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include ion channel activity and calcium channel activity. An important paralog of this gene is TRPC5.
UniProtKB/Swiss-Prot for TRPC1 Gene
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.