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TRMT61A Gene

protein-coding   GIFtS: 50
GCID: GC14P103995

TRNA Methyltransferase 61 Homolog A (S. Cerevisiae)

(Previous name: chromosome 14 open reading frame 172)
(Previous symbol: C14orf172)
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Aliases
for TRMT61A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TRNA Methyltransferase 61 Homolog A (S. Cerevisiae)1 2     hTRM612
C14orf1721 2 3     TRNA (Adenine(58)-N(1))-Methyltransferase Catalytic Subunit TRMT61A2
TRM612 3     TRNA (Adenine-N(1)-)-Methyltransferase Catalytic Subunit TRM612
TRNA(M1A58)-Methyltransferase Subunit TRMT61A2 3     TRNA (Adenine-N(1)-)-Methyltransferase Catalytic Subunit TRMT61A2
TRNA(M1A58)MTase Subunit TRMT61A2 3     TRNA(M1A58)-Methyltransferase Subunit TRM612
Chromosome 14 Open Reading Frame 1721     TRNA(M1A58)MTase Subunit TRM612
GCD142     EC 2.1.1.2203
Gcd14p2     EC 2.1.1.368

External Ids:    HGNC: 237901   Entrez Gene: 1157082   Ensembl: ENSG000001661667   UniProtKB: Q96FX73   

Export aliases for TRMT61A gene to outside databases

Previous GC identifers: GC14P103067 GC14P084173


Summaries
for TRMT61A gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TRMT61A Gene:
TRMT61A (tRNA methyltransferase 61 homolog A (S. cerevisiae)) is a protein-coding gene. GO annotations related to this gene include tRNA (adenine-N1-)-methyltransferase activity.

UniProtKB/Swiss-Prot: TRM61_HUMAN, Q96FX7
Function: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of
N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA




Genomic Views
for TRMT61A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRMT61A gene promoter:
         Max1   USF1   AP-2alpha isoform 3   USF-1:USF-2   AP-2alpha isoform 2   SRY   USF-1   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TRMT61A promoter sequence
   Search Chromatin IP Primers for TRMT61A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRMT61A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32   Ensembl cytogenetic band:  14q32.32   HGNC cytogenetic band: 14q32

TRMT61A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRMT61A gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P103995:  view genomic region     (about GC identifiers)

Start:
 103,995,509 bp from pter      End:
 104,003,410 bp from pter
Size:
 7,902 bases      Orientation:
 plus strand

Proteins
for TRMT61A gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TRM61_HUMAN, Q96FX7 (See protein sequence)
Recommended Name: tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A  
Size: 289 amino acids; 31382 Da
Subunit: tRNA (adenine-N(1)-)-methyltransferase is a heterodimer of TRM6 and TRM61
Sequence caution: Sequence=BAC05168.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
Secondary accessions: A6NN78 Q8N7Q9

Explore the universe of human proteins at neXtProt for TRMT61A: NX_Q96FX7

Explore proteomics data for TRMT61A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
    • 3 DME Specific Peptides for TRMT61A (Q96FX7)
     LPHRTQI  PTPELWT  GHTGYLTFA 


    See TRMT61A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689520.2  
    ENSEMBL proteins: 
     ENSP00000374399   ENSP00000299202  

    TRMT61A Human Recombinant Protein Products:

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    Novus Biologicals TRMT61A Protein
    Novus Biologicals TRMT61A Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRMT61A

         		 Search eBioscience for Proteins for TRMT61A 

         		antibodies-online proteins for TRMT61A (5 products) 

         		antibodies-online peptides for TRMT61A

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    TRMT61A Assay Products:

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    Cloud-Clone Corp. ELISAs for TRMT61A
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    antibodies-online kits for TRMT61A (8 products) 

    Domains /
    Families
    for TRMT61A gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    TryGeneCards Plus    		 1 InterPro protein domain:
     IPR014816 tRNA_MeTrfase_Gcd14

    Graphical View of Domain Structure for InterPro Entry Q96FX7

    ProtoNet protein and cluster: Q96FX7

    UniProtKB/Swiss-Prot: TRM61_HUMAN, Q96FX7
    Similarity: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family


    Find genes that share domains with TRMT61A           About GenesLikeMe


    Function
    for TRMT61A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRM61_HUMAN, Q96FX7
    Function: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of
    N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA
    Catalytic activity: S-adenosyl-L-methionine + adenine(58) in tRNA = S-adenosyl-L-homocysteine +
    N(1)-methyladenine(58) in tRNA

         Enzyme Numbers (IUBMB): EC 2.1.1.362 EC 2.1.1.2201

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016429tRNA (adenine-N1-)-methyltransferase activity IEA--
         
    Find genes that share ontologies with TRMT61A           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for TRMT61A:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Decreased viability of wild-ty 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TRMT61A

    miRNA
    Products:            		miRTarBase miRNAs that target TRMT61A:
    hsa-mir-92a-3p (MIRT049081), hsa-mir-342-3p (MIRT043665), hsa-mir-769-5p (MIRT039179)

    Block miRNA regulation of human, mouse, rat TRMT61A using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate TRMT61A:
    hsa-miR-1184 hsa-miR-4254 hsa-miR-544 hsa-miR-196a* hsa-miR-2355-3p hsa-miR-591 hsa-miR-608
    SwitchGear 3'UTR luciferase reporter plasmid: TRMT61A 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for TRMT61A
    Predesigned siRNA for gene silencing in human, mouse, rat TRMT61A

    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
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    Localization
    for TRMT61A gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TRM61_HUMAN, Q96FX7: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus2
    cytosol1
    extracellular1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0031515tRNA (m1A) methyltransferase complex IEA--

    Find genes that share ontologies with TRMT61A           About GenesLikeMe


    Pathways & Interactions
    for TRMT61A gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRMT61A
    Interactions:

        Search GeneGlobe Interaction Network for TRMT61A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TRMT61A (Q96FX73 ENSP000003743994) via UniProtKB, MINT, STRING, and/or I2D (see all 76)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DDX55Q8NHQ93, ENSP000002381464I2D: score=1 STRING: ENSP00000238146
    EIF2AK4Q9P2K83, ENSP000002637914I2D: score=1 STRING: ENSP00000263791
    FARS2O953633, ENSP000002746804I2D: score=1 STRING: ENSP00000274680
    FKBP1AP629423, ENSP000003711384I2D: score=1 STRING: ENSP00000371138
    MRTO4Q9UKD23, ENSP000003643204I2D: score=1 STRING: ENSP00000364320
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030488tRNA methylation ----

    Find genes that share ontologies with TRMT61A           About GenesLikeMe



    Drugs & Compounds
    for TRMT61A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRMT61A (TRM61)

    2 HMDB Compounds for TRMT61A    About this table
    CompoundSynonyms CAS #PubMed Ids
    S-Adenosylhomocysteine(S)-5'-(S)-(3-Amino-3-carboxypropyl)-5'-thioadenosine (see all 19)979-92-0--
    S-Adenosylmethionine(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine (see all 16)29908-03-0--



    Transcripts
    for TRMT61A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRMT61A gene: 
    NM_152307.2  

    Unigene Cluster for TRMT61A:

    TRNA methyltransferase 61 homolog A (S. cerevisiae)
    Hs.525610  [show with all ESTs]
    Unigene Representative Sequence: NM_152307
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389749(uc001yng.3 uc010aws.3) ENST00000299202
    miRNA
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    7 qRT-PCR Assays for microRNAs that regulate TRMT61A:
    hsa-miR-1184 hsa-miR-4254 hsa-miR-544 hsa-miR-196a* hsa-miR-2355-3p hsa-miR-591 hsa-miR-608
    SwitchGear 3'UTR luciferase reporter plasmid: TRMT61A 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRMT61A
    Clone
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    GenScript: all cDNA clones in your preferred vector: TRMT61A (NM_152307)
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    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TRMT61A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRMT61A
      QuantiTect SYBR Green Assays in human, mouse, rat TRMT61A
      QuantiFast Probe-based Assays in human, mouse, rat TRMT61A

    Additional mRNA sequence: 

    BC007241.1 BC010167.2 BC016033.2 

    9 DOTS entries:

    DT.306574  DT.97840423  DT.100762946  DT.100772513  DT.100796595  DT.100833855  DT.75141547  DT.91761682 
    DT.120788522 

    Selected AceView cDNA sequences (see all 142):

    BQ648018 BE276214 AW196578 AA338075 BC010167 BM669685 CR620786 BE048174 
    CR624022 CR605570 CR599923 BM698902 AA319355 CR625555 AI168476 BQ950130 
    AI573079 AI885413 CR597205 AI668655 CR616463 BX361326 BG478727 AI734254 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for TRMT61A    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
    SP1:                                    
    SP2:              -                     


    ECgene alternative splicing isoforms for TRMT61A

    Expression
    for TRMT61A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRMT61A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGGAGGCCG
    TRMT61A Expression
    About this image

    TRMT61A Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    TRMT61A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.525610
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    In Situ
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    Orthologs
    for TRMT61A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TRMT61A gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Trmt61a1 , 5 tRNA methyltransferase 61 homolog A (S. cerevisiae)5
    tRNA methyltransferase 61A1    		 85.93(n)1
    91.35(a)1    		   12 (61.09 cM)5
    3281621  NM_001099792.11  NP_001093262.11 
     1116781055 
    chicken
    (Gallus gallus)    		 Aves TRMT61A1 tRNA methyltransferase 61 homolog A (S. cerevisiae) 67.83(n)
    72.13(a)    		   423481  XM_421386.4  XP_421386.4 
    lizard
    (Anolis carolinensis)    		 Reptilia TRMT61A6
    		 tRNA methyltransferase 61 homolog A (S. cerevisiae...
    		 67(a)
    		 1 ↔ 1
    		 GL343232.1(32338-90502)
    African clawed frog
    (Xenopus laevis)    		 Amphibia MGC533122 hypothetical protein MGC53312 73.18(n)    BC042219.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii trmt61a1 tRNA methyltransferase 61 homolog A (S. cerevisiae) 65.73(n)
    70.63(a)    		   436593  NM_001002321.1  NP_001002321.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG145441 CG14544 55.17(n)
    50.87(a)    		   43170  NM_143204.3  NP_651461.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea CELE_W02A11.11 CELE_W02A11.1 53.93(n)
    50.21(a)    		   173142  NM_060828.4  NP_493229.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes GCD141 GCD14 46.95(n)
    44.68(a)    		   853317   NP_012410.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G146001 AT5G14600 49.82(n)
    48.74(a)    		   831312  NM_121464.1  NP_568302.1 
    rice
    (Oryza sativa)    		 Liliopsida Os04g03263001 Os04g0326300 55.02(n)
    49.63(a)    		   4335490  NM_001059009.2  NP_001052474.2 


    ENSEMBL Gene Tree for TRMT61A (if available)
    TreeFam Gene Tree for TRMT61A (if available)

    Paralogs
    for TRMT61A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Genomic Variants
    for TRMT61A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRMT61A (see all 226)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1830099301,2
    		--103993577(+) TCAATA/GAGATG 1 -- us2k10--------
    rs1446102281,2
    		C--103993826(+) GGAAA-/CCCACC 1 -- us2k10--------
    rs1421177781,2
    		--103993864(+) CCTTAA/TAGGCA 1 -- us2k10--------
    rs563248431,2
    		C,F--103993875(+) CCCGGC/ACCTGA 1 -- us2k13Minor allele frequency- A:0.22WA 122
    rs1851538971,2
    		--103993898(+) CACAGC/TTGAGA 1 -- us2k10--------
    rs1457113711,2
    		--103993938(+) GAAAGC/TCAGAA 1 -- us2k10--------
    rs1481033051,2
    		--103994074(+) GAGGCC/TGTAAG 1 -- us2k10--------
    rs1434402871,2
    		--103994112(+) GTGGT-/GGGCCC 1 -- us2k10--------
    rs1118350851,2
    		C--103994273(+) CAAGGG/ACCACA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1418426841,2
    		--103994358(+) AGCTCA/GCTCTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TRMT61A (103995509 - 104003410 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for TRMT61A:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1992n71CNV Loss21882294
    nsv832883CNV Loss17160897
    dgv1993n71CNV Loss21882294
    nsv827068CNV Loss20364138
    nsv902300CNV Loss21882294
    dgv1994n71CNV Loss21882294
    nsv9170CNV Gain18304495

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    Disorders / Diseases
    for TRMT61A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Publications
    for TRMT61A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRMT61A gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with TRMT61A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The bipartite structure of the tRNA m1A58 methyltransferase from S. cerevisiae is conserved in humans. (PubMed id 16043508)1, 2, 3 Ozanick S.... Anderson J.T. (RNA 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PubMed id 22223895)2 Bienvenut W.V....Giglione C. (amp 2012)
    7. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)

    External Searches for TRMT61A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing TRMT61A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 115708 HGNC: 23790 AceView: FLJ40452 Ensembl:ENSG00000166166 euGenes: HUgn115708
    ECgene: TRMT61A H-InvDB: TRMT61A

    Other Databases showing TRMT61A gene

    (According to HUGE)
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    Specialized Databases showing TRMT61A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRMT61A Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TRMT61A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for TRMT61A gene:
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