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TRMT2B Gene

protein-coding   GIFtS: 50
GCID: GC0XM100264

TRNA Methyltransferase 2 Homolog B (S. Cerevisiae)

(Previous name: chromosome X open reading frame 34)
(Previous symbol: CXorf34)
Microbiology & Infectious Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TRNA Methyltransferase 2 Homolog B (S. Cerevisiae)1 2     dJ341D10.32
CXorf341 2 3     TRM2 TRNA Methyltransferase 2 Homolog B2
TRM2 Homolog2 3     TRNA (Uracil(54)-C(5))-Methyltransferase Homolog2
EC 2.1.1.353 8     TRNA (Uracil-5-)-Methyltransferase Homolog2
Chromosome X Open Reading Frame 341     

External Ids:    HGNC: 257481   Entrez Gene: 799792   Ensembl: ENSG000001889177   UniProtKB: Q96GJ13   

Export aliases for TRMT2B gene to outside databases

Previous GC identifers: GC0XM100150 GC0XM090068


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRMT2B Gene:
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase
that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in
DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.
(provided by RefSeq, Nov 2009)

GeneCards Summary for TRMT2B Gene:
TRMT2B (tRNA methyltransferase 2 homolog B (S. cerevisiae)) is a protein-coding gene. Diseases associated with TRMT2B include pneumonia. GO annotations related to this gene include S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity. An important paralog of this gene is TRMT2A.

UniProtKB/Swiss-Prot: TRM2_HUMAN, Q96GJ1
Function: Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of
5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRMT2B gene promoter:
         HOXA9   HOXA9B   RFX1   Brachyury   Gfi-1   POU2F1   POU2F1a   HOXA5   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRMT2B promoter sequence
   Search Chromatin IP Primers for TRMT2B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRMT2B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.1   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22.1

TRMT2B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRMT2B gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM100264:  view genomic region     (about GC identifiers)

Start:
100,264,334 bp from pter      End:
100,307,105 bp from pter
Size:
42,772 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TRM2_HUMAN, Q96GJ1 (See protein sequence)
Recommended Name: tRNA (uracil(54)-C(5))-methyltransferase homolog  
Size: 504 amino acids; 56476 Da
Secondary accessions: A6NDG5 A6NEI9 A6NMG6 Q5JPF0 Q5JVY6 Q96HU7 Q96IH9 Q9H9K2
Alternative splicing: 3 isoforms:  Q96GJ1-1   Q96GJ1-2   Q96GJ1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRMT2B: NX_Q96GJ1

Explore proteomics data for TRMT2B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for TRMT2B (Q96GJ1)
     EQAVEDA  TMTRCSH 


    See TRMT2B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001161442.1  NP_001161443.1  NP_001161444.1  NP_079193.2  

    ENSEMBL proteins: 
     ENSP00000362030   ENSP00000362026   ENSP00000362027   ENSP00000340970   ENSP00000438134  
     ENSP00000362022  

    TRMT2B Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR025714 Methyltranfer_dom
     IPR025823 tRNA_(uracil-5-)_MeTrfase_met

    Graphical View of Domain Structure for InterPro Entry Q96GJ1

    ProtoNet protein and cluster: Q96GJ1

    UniProtKB/Swiss-Prot: TRM2_HUMAN, Q96GJ1
    Similarity: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase
    family


    TRMT2B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRM2_HUMAN, Q96GJ1
    Function: Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of
    5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation (By
    similarity)
    Catalytic activity: S-adenosyl-L-methionine + uracil(54) in tRNA = S-adenosyl-L-homocysteine + 5-methyluracil(54)
    in tRNA

         Enzyme Number (IUBMB): EC 2.1.1.351 2

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity ----
    GO:0008173RNA methyltransferase activity ----
    GO:0030697S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity IEA--
         
    TRMT2B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TRMT2B:
     Decreased Wnt reporter activit 

    Animal Models:
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    miRTarBase miRNAs that target TRMT2B:
    hsa-mir-26b-5p (MIRT028766)

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    8 qRT-PCR Assays for microRNAs that regulate TRMT2B:
    hsa-miR-485-5p hsa-miR-137 hsa-miR-4268 hsa-miR-3942-5p hsa-miR-3120-3p hsa-miR-500a hsa-miR-1182 hsa-miR-556-3p
    SwitchGear 3'UTR luciferase reporter plasmidTRMT2B 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    cytosol1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    TRMT2B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRMT2B
    Interactions:

        Search GeneGlobe Interaction Network for TRMT2B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for TRMT2B (ENSP000003620264) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAD52ENSP000003512844STRING: ENSP00000351284
    EXO1ENSP000003118734STRING: ENSP00000311873
    NOLC1ENSP000003590244STRING: ENSP00000359024
    EIF3JENSP000002618684STRING: ENSP00000261868
    GPATCH4ENSP000003964414STRING: ENSP00000396441
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006396RNA processing ----

    TRMT2B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRMT2B (TRM2)

    1 HMDB Compound for TRMT2B    About this table
    CompoundSynonyms CAS #PubMed Ids
    Ribothymidine1-b-D-Ribofuranosylthymine (see all 17)1463-10-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TRMT2B gene (4 alternative transcripts): 
    NM_001167970.1  NM_001167971.1  NM_001167972.1  NM_024917.5  

    Unigene Cluster for TRMT2B:

    TRNA methyltransferase 2 homolog B (S. cerevisiae)
    Hs.496501  [show with all ESTs]
    Unigene Representative Sequence: NM_024917
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372939 ENST00000372935 ENST00000372936 ENST00000478422 ENST00000488615
    ENST00000338687(uc004egr.3 uc004egv.3) ENST00000545398(uc004egt.3 uc004egq.3 uc004egs.3 uc004egu.3)
    ENST00000372931
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    8 qRT-PCR Assays for microRNAs that regulate TRMT2B:
    hsa-miR-485-5p hsa-miR-137 hsa-miR-4268 hsa-miR-3942-5p hsa-miR-3120-3p hsa-miR-500a hsa-miR-1182 hsa-miR-556-3p
    SwitchGear 3'UTR luciferase reporter plasmidTRMT2B 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat TRMT2B

    Additional mRNA sequence: 

    AK022749.1 AK315780.1 AL832849.1 BC008067.2 BC009437.1 BC020116.1 BC034272.2 BX647969.1 

    16 DOTS entries:

    DT.95126701  DT.101984366  DT.70104983  DT.91765842  DT.121281428  DT.91765841  DT.95310537  DT.95126689 
    DT.100027702  DT.100789397  DT.100789400  DT.121281433  DT.91765849  DT.95362513  DT.92349294  DT.95144903 

    Selected AceView cDNA sequences (see all 130):

    W39709 BG473171 BQ919445 BQ059395 BQ643429 BE734445 BQ423218 BQ055470 
    BG481630 BE258334 BQ052955 BE409102 AL556799 BQ952071 CR605503 BG390275 
    BQ063167 BE256957 BI160971 NM_024917 BI333489 BG822657 BG759512 BC009437 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TRMT2B (see all 24)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c · 8d · 8e ^ 9a · 9b · 9c ^
    SP1:                                      -     -     -     -     -                                                                                             
    SP2:                                      -                                                                                                                     
    SP3:                                      -           -     -     -                                                                                             
    SP4:                                      -           -     -     -     -     -     -                 -     -                                                   
    SP5:                                            -     -     -     -                                                                                             

    ExUns: 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b
    SP1:                                                                        
    SP2:                                                        -               
    SP3:                                                        -               
    SP4:                                                                        
    SP5:                                                                        


    ECgene alternative splicing isoforms for TRMT2B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRMT2B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGTGAATAC
    TRMT2B Expression
    About this image

    TRMT2B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRMT2B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.496501
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TRMT2B gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trmt2b1 , 5 TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)5
    TRM2 tRNA methyltransferase 2B1
    82.35(n)1
    76.27(a)1
      X (55.95 cM)5
    2152011  NM_172540.21  NP_766128.21 
     1342223395 
    chicken
    (Gallus gallus)
    Aves LOC1008589091 tRNA (uracil-5-)-methyltransferase homolog 67.77(n)
    65.17(a)
      100858909  XM_004950093.1  XP_004950150.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia trmt2b1 tRNA methyltransferase 2 homolog B (S. cerevisiae) 60.2(n)
    54.5(a)
      100495482  XM_002939204.2  XP_002939250.2 
    zebrafish
    (Danio rerio)
    Actinopterygii trmt2b1 TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae) 58.5(n)
    55.73(a)
      606657  NM_001122943.1  NP_001116415.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG38086
    --
    25(a)
    1 → many
    3L(18990975-18993708)
    worm
    (Caenorhabditis elegans)
    Secernentea H24K24.46
    Protein H24K24.4 (H24K24.4) mRNA, complete cds
    23(a)
    1 → many
    V(904950-911604) WBGene00019241
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TRM26
    tRNA methyltransferase, 5-methylates the uridine r...
    13(a)
    1 → many
    XI(549448-551367) YKR056W


    ENSEMBL Gene Tree for TRMT2B (if available)
    TreeFam Gene Tree for TRMT2B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRMT2B gene
    TRMT2A2  
    2 SIMAP similar genes for TRMT2B using alignment to 2 protein entries:     TRM2_HUMAN (see all proteins):
    TUBA1C    TRMT2A

    TRMT2B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TRMT2B
    PGOHUM00000245120


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRMT2B (see all 659)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1379371931,2
    C--100230751(+) TCTGTC/GTTCTG 4 -- ds50010--------
    rs1425038261,2
    --100230768(+) GCCCAC/TCCTGG 4 -- ds50010--------
    rs20140061,2
    C,F--100231412(-) ctgaaA/Tttgtg 4 -- ut313Minor allele frequency- T:0.00NA EA 252
    rs1459365441,2
    --100231531(+) CATTCA/GAGATG 4 -- ut310--------
    rs107115061,2
    C--100231584(+) GATCA-/CTCAGT 4 -- ut310--------
    rs66209771,2
    C--100231739(+) CAATGT/GAAAAT 4 -- ut311Minor allele frequency- G:0.00NA 2
    rs1872600161,2
    --100231772(+) GTCATG/TTGTCC 4 -- ut310--------
    rs1486205791,2
    --100231898(+) CATGAC/TTGAAA 4 -- ut310--------
    rs1922374711,2
    --100231978(+) TTTGAA/GAGGCC 4 -- ut310--------
    rs1839097991,2
    --100231984(+) AGGCCA/GAGGCG 4 -- ut310--------

    HapMap Linkage Disequilibrium report for TRMT2B (100264334 - 100307105 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TRMT2B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv7013CNV Loss18451855
    nsv515758CNV Gain19592680
    nsv517937CNV Gain19592680

    Locus Specific Mutation Databases (LSDB): TRMT2B

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for TRMT2B:    About MalaCards
    pneumonia


    TRMT2B for disorders           About GeneDecksing


    Export disorders for TRMT2B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRMT2B gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TRMT2B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    4. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    6. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79979 HGNC: 25748 AceView: CXorf34 Ensembl:ENSG00000188917 euGenes: HUgn79979
    ECgene: TRMT2B H-InvDB: TRMT2B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRMT2B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRMT2B gene:
    Search GeneIP for patents involving TRMT2B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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