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TRMT1L Gene

protein-coding   GIFtS: 42
GCID: GC01M185088

TRNA Methyltransferase 1 Homolog (S. Cerevisiae)-Like

(Previous names: chromosome 1 open reading frame 25, TRM1 tRNA methyltransferase...)
(Previous symbol: C1orf25)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TRNA Methyltransferase 1 Homolog (S. Cerevisiae)-Like1 2     MST0702
C1orf251 2 3 5     bG120K12.32
TRM1L2 3 5     TRM1-Like Protein2
TRM1 TRNA Methyltransferase 1-Like1 2     TRMT1-Like Protein2
TRM1-like1     EC 2.1.1.-3
Chromosome 1 Open Reading Frame 251     

External Ids:    HGNC: 167821   Entrez Gene: 816272   Ensembl: ENSG000001214867   OMIM: 6116735   UniProtKB: Q7Z2T53   

Export aliases for TRMT1L gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRMT1L Gene:
This gene encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other
organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and
exploratory behavior, and it may also be involved in modulating postnatal neuronal functions. Alternatively
spliced transcripts have been identified for this gene. (provided by RefSeq, Jan 2011)

GeneCards Summary for TRMT1L Gene:
TRMT1L (tRNA methyltransferase 1 homolog (S. cerevisiae)-like) is a protein-coding gene. Diseases associated with TRMT1L include neuronitis, and prostate cancer. GO annotations related to this gene include tRNA binding and tRNA (guanine-N2-)-methyltransferase activity. An important paralog of this gene is TRMT1.

UniProtKB/Swiss-Prot: TRM1L_HUMAN, Q7Z2T5
Function: May play a role in motor coordination and exploratory behavior (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_004487.20  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TRMT1L
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRMT1L promoter sequence
   Search Chromatin IP Primers for TRMT1L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRMT1L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q25.2   Ensembl cytogenetic band:  1q25.3   HGNC cytogenetic band: 1q25.2

TRMT1L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRMT1L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M185088:  view genomic region     (about GC identifiers)

Start:
185,087,217 bp from pter      End:
185,126,230 bp from pter
Size:
39,014 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TRM1L_HUMAN, Q7Z2T5 (See protein sequence)
Recommended Name: TRMT1-like protein  
Size: 733 amino acids; 81747 Da
Sequence caution: Sequence=AAH39738.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=AAQ13590.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAI17851.1; Type=Erroneous gene model prediction;
Secondary accessions: Q5TEN0 Q6ZMX0 Q8IWH5 Q8NC68 Q9BZQ1
Alternative splicing: 2 isoforms:  Q7Z2T5-1   Q7Z2T5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRMT1L: NX_Q7Z2T5

Explore proteomics data for TRMT1L at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRMT1L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001189352.1  NP_112196.3  

    ENSEMBL proteins: 
     ENSP00000356476   ENSP00000414339   ENSP00000356474  

    TRMT1L Human Recombinant Protein Products:

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    Novus Biologicals TRMT1L Protein
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR002905 Trm1
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q7Z2T5

    ProtoNet protein and cluster: Q7Z2T5

    UniProtKB/Swiss-Prot: TRM1L_HUMAN, Q7Z2T5
    Similarity: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family
    Similarity: Contains 1 C2H2-type zinc finger
    Similarity: Contains 1 Trm1 methyltransferase domain


    TRMT1L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRM1L_HUMAN, Q7Z2T5
    Function: May play a role in motor coordination and exploratory behavior (By similarity)

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000049tRNA binding IEA--
    GO:0003723RNA binding ----
    GO:0004809tRNA (guanine-N2-)-methyltransferase activity IEA--
    GO:0016740transferase activity ----
    GO:0044822poly(A) RNA binding IDA--
         
    TRMT1L for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TRMT1L:
     Increased HPV18 LCR reporter a 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Trmt1l):
     behavior/neurological  reproductive system 

    TRMT1L for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRMT1L
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRMT1L
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRMT1L

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TRMT1L (see all 27):
    hsa-miR-3607-5p hsa-let-7d hsa-miR-4251 hsa-let-7c hsa-let-7g hsa-miR-661 hsa-let-7a hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmidTRMT1L 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRMT1L

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    GenScript: all cDNA clones in your preferred vector (see all 2): TRMT1L (NM_030934)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRMT1L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRMT1L

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRMT1L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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      --

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRMT1L
    Interactions:

        Search GeneGlobe Interaction Network for TRMT1L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TRMT1L (Q7Z2T52, 3 ENSP000003564764) via UniProtKB, MINT, STRING, and/or I2D (see all 599)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=3 STRING: ENSP00000367207
    PPP4CP605103, ENSP000002793874I2D: score=1 STRING: ENSP00000279387
    TRUB1Q8WWH52, ENSP000002987464MINT-7947479 STRING: ENSP00000298746
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    CDC5LQ994592, ENSP000003605324MINT-7947479 STRING: ENSP00000360532
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008033tRNA processing ----
    GO:0008344adult locomotory behavior IEA--
    GO:0030534adult behavior ----

    TRMT1L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRMT1L (TRM1L)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TRMT1L gene (2 alternative transcripts): 
    NM_001202423.1  NM_030934.4  

    Unigene Cluster for TRMT1L:

    TRNA methyltransferase 1 homolog (S. cerevisiae)-like
    Hs.107149  [show with all ESTs]
    Unigene Representative Sequence: NM_030934
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367506 ENST00000465827 ENST00000458395 ENST00000487028 ENST00000367504(uc001grf.4 uc010pon.2)

    miRNA
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    Block miRNA regulation of human, mouse, rat TRMT1L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TRMT1L (see all 27):
    hsa-miR-3607-5p hsa-let-7d hsa-miR-4251 hsa-let-7c hsa-let-7g hsa-miR-661 hsa-let-7a hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmidTRMT1L 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRMT1L
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TRMT1L (NM_030934)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRMT1L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRMT1L
    Primer
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    OriGene qPCR primer pairs and template standards for TRMT1L
    OriGene qSTAR qPCR primer pairs in human, mouse for TRMT1L
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRMT1L
      QuantiTect SYBR Green Assays in human, mouse, rat TRMT1L
      QuantiFast Probe-based Assays in human, mouse, rat TRMT1L

    Additional mRNA sequence: 

    AF163261.1 AF288399.1 AK027418.1 AK074936.1 AK074993.1 AK098359.1 AK226103.1 AK302166.1 
    AK312801.1 BC026883.1 BC035430.1 BC039738.1 BC045535.1 BC053961.1 

    6 DOTS entries:

    DT.105480  DT.102825556  DT.40305804  DT.97857217  DT.99935150  DT.112969 

    Selected AceView cDNA sequences (see all 113):

    AL046178 C00896 AI379497 BM801578 BX499933 AI476656 AW576498 AF163261 
    AA788999 NM_030934 AA369197 AW572698 BX282707 CB128464 AW512122 BM722945 
    AK074993 AW003172 CA429717 BQ214011 AL120995 AI651996 BC045535 BM969965 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TRMT1L    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b · 17c
    SP1:        -     -                                                                       -                 -           -                           
    SP2:                                                                                                        -           -                           
    SP3:                                                                                      -                                                         
    SP4:              -                                                                                                                                 
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for TRMT1L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRMT1L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TRMT1L Expression
    About this image

    TRMT1L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRMT1L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.107149

    UniProtKB/Swiss-Prot: TRM1L_HUMAN, Q7Z2T5
    Tissue specificity: Widely expressed

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TRMT1L gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trmt1l1 , 5 RIKEN cDNA 1190005F20 gene5
    tRNA methyltransferase 1 like1
    86.72(n)1
    88.32(a)1
      1 (64.12 cM)5
    986851  NM_026876.31  NP_081152.21 
     1514286485 
    chicken
    (Gallus gallus)
    Aves TRMT1L1 TRM1 tRNA methyltransferase 1-like 75.03(n)
    72.29(a)
      426860  XM_003643174.2  XP_003643222.2 
    lizard
    (Anolis carolinensis)
    Reptilia TRMT1L6
    tRNA methyltransferase 1 homolog (S. cerevisiae)-l...
    66(a)
    1 ↔ 1
    GL343203.1(3202636-3225737)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.339862 Xenopus laevis transcribed sequence with weak similarity more 73.69(n)    BI442875.1 
    zebrafish
    (Danio rerio)
    Actinopterygii trmt1l1 tRNA methyltransferase 1 homolog (S. cerevisiae)-like 62.9(n)
    63.87(a)
      559583  XM_682939.4  XP_688031.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG63886
    --
    18(a)
    1 → many
    2L(12428028-12430021)
    worm
    (Caenorhabditis elegans)
    Secernentea trm-16
    Protein TRM-1 (trm-1) mRNA, complete cds
    17(a)
    1 → many
    V(14183124-14185623) WBGene00006613
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TRM16
    tRNA methyltransferase; two forms of the protein a...
    16(a)
    1 → many
    IV(691549-693261) YDR120C


    ENSEMBL Gene Tree for TRMT1L (if available)
    TreeFam Gene Tree for TRMT1L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRMT1L gene
    TRMT12  

    TRMT1L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRMT1L (see all 583)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1390949581,2
    C--185086804(+) TAGTC-/TTGACT 2 -- ds50010--------
    rs109116791,2
    C,F,A,H--185086991(+) GAAATT/ACCTAG 2 -- ds500128Minor allele frequency- A:0.32NS EA NA WA CSA 2761
    rs730669341,2
    C,F--185087006(+) TTCGGG/ACTCAC 2 -- ds50012Minor allele frequency- A:0.03WA 120
    rs1158384411,2
    C,F--185087028(+) AATTAG/ATCCTA 2 -- ds50011Minor allele frequency- A:0.05WA 118
    rs1408513501,2
    --185087037(+) TAATTC/TTGGGC 2 -- ds50010--------
    rs1929825411,2
    --185087058(+) TCAAAC/GACTTA 2 -- ds50010--------
    rs1842353831,2
    --185087060(+) AAACAC/TTTATT 2 -- ds50010--------
    rs1493739681,2
    C--185087106(+) GTTTTA/GACCCA 2 -- ds50010--------
    rs771775281,2
    C,F--185087228(+) TAACTC/TGTTCT 2 -- ut311Minor allele frequency- T:0.07NA 120
    rs1447028651,2
    --185087274(+) ATGCTA/GCTTTA 2 -- ut310--------

    HapMap Linkage Disequilibrium report for TRMT1L (185087217 - 185126230 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TRMT1L:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv872588CNV Loss21882294
    nsv521613CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611673    OMIM disorders: --

    4 diseases for TRMT1L:    
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    neuronitis    prostate cancer    prostatitis    hiv-1


    TRMT1L for disorders           About GeneDecksing


    Export disorders for TRMT1L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRMT1L gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with TRMT1L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. (PubMed id 11318611)1, 2, 3 Sood R....Carpten J.D. (Genomics 2001)
    2. The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour. (PubMed id 17198746)1, 3 Vauti F....Arnold H.H. (Gene 2007)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    6. Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (amp 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Purification and identification of endogenous polySUMO conjugates. (PubMed id 21252943)1 Bruderer R....Hay R.T. (EMBO Rep. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81627 HGNC: 16782 AceView: C1orf25 Ensembl:ENSG00000121486 euGenes: HUgn81627
    ECgene: TRMT1L H-InvDB: TRMT1L

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRMT1L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRMT1L gene:
    Search GeneIP for patents involving TRMT1L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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