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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRMT12 Gene

protein-coding   GIFtS: 46
GCID: GC08P125463

TRNA Methyltransferase 12 Homolog (S. Cerevisiae)

(Previous name: tRNA methyltranferase 12 homolog (S. cerevisiae))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
TRNA Methyltransferase 12 Homolog (S. Cerevisiae)1 2     Homolog Of Yeast TRNA Methyltransferase2
TRNA-YW Synthesizing Protein 21 2     TRNA Methyltranferase 12 Homolog2
Alpha-Amino-Alpha-Carboxypropyl Transferase TYW22 3     TRNA Wybutosine-Synthesizing Protein 2 Homolog2
TRM122 3     EC 2.5.1.-3
TYW22 3     EC 2.1.18
TRNA-YW-Synthesizing Protein 22 3     EC 2.1.1.328
TRNA Methyltranferase 12 Homolog (S. Cerevisiae)1     

External Ids:    HGNC: 260911   Entrez Gene: 550392   Ensembl: ENSG000001836657   OMIM: 6112445   UniProtKB: Q53H543   

Export aliases for TRMT12 gene to outside databases

Previous GC identifers: GC08P125534 GC08P120788


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRMT12 Gene:
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine
tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of
a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).(supplied by OMIM, Mar 2008)

GeneCards Summary for TRMT12 Gene: 
TRMT12 (tRNA methyltransferase 12 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with TRMT12 include noma, and breast cancer. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot: TYW2_HUMAN, Q53H54
Function: Probable S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine
biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position
adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity)

Gene Wiki entry for TRMT12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRMT12 gene promoter:
         Max1   Pbx1a   SREBP-1c   Nkx5-1   SREBP-1b   GATA-2   Max   AREB6   SREBP-1a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRMT12 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRMT12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRMT12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.13   Ensembl cytogenetic band:  8q24.13   HGNC cytogenetic band: 8q24.13

TRMT12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRMT12 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P125463:  view genomic region     (about GC identifiers)

Start:
125,463,048 bp from pter      End:
125,474,391 bp from pter
Size:
11,344 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TYW2_HUMAN, Q53H54 (See protein sequence)
Recommended Name: tRNA wybutosine-synthesizing protein 2 homolog  
Size: 448 amino acids; 50236 Da
Sequence caution: Sequence=AAH03057.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAH03057.2; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence
starting in position 371;
Secondary accessions: Q6PKB9 Q96F21 Q9NWK6

Explore the universe of human proteins at neXtProt for TRMT12: NX_Q53H54

Explore proteomics data for TRMT12 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q53H54

  • 4/6 DME Specific Peptides for TRMT12 (Q53H54) (see all 6)
     NLEINGV  GNITEKLR  VHACEWNP  LLSEDCFQA 

    TRMT12 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRMT12 Protein Expression
    REFSEQ proteins: NP_060426.2  
    ENSEMBL proteins: 
     ENSP00000429771   ENSP00000329858  

    Human Recombinant Protein Products for TRMT12: 
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    Novus Biologicals TRMT12 Proteins
    Novus Biologicals TRMT12 Lysates
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    Browse Proteins at Cloud-Clone Corp. 


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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR003402 tRNA_Trfase_Trm5/Tyw2

    Graphical View of Domain Structure for InterPro Entry Q53H54

    ProtoNet protein and cluster: Q53H54

    1 Blocks protein domain: IPB003402 Family of unknown function Met10

    UniProtKB/Swiss-Prot: TYW2_HUMAN, Q53H54
    Similarity: Belongs to the TRM5 / TYW2 family


    TRMT12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TYW2_HUMAN, Q53H54
    Function: Probable S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine
    biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position
    adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity)

         Enzyme Numbers (IUBMB): EC 2.1.12 EC 2.1.1.322 EC 2.5.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity IEA--
    GO:0016740transferase activity ----
         
    TRMT12 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRMT12 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRMT12 
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    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TRMT12:
    hsa-miR-629* hsa-miR-32* hsa-miR-450b-5p
    SwitchGear 3'UTR luciferase reporter plasmidTRMT12 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRMT12


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: TYW2_HUMAN, Q53H54
    Pathway: tRNA modification; wybutosine-tRNA(Phe) biosynthesis

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRMT12

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008033tRNA processing IEA--

    TRMT12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRMT12 (TYW2)

    1 HMDB Compound for TRMT12    About this table
    CompoundSynonyms CAS #PubMed Ids
    S-Adenosylmethionine(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine (see all 16)29908-03-0--

    Search CenterWatch for drugs/clinical trials and news about TRMT12 / TYW2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRMT12 gene: 
    NM_017956.3  

    Unigene Cluster for TRMT12:

    TRNA methyltransferase 12 homolog (S. cerevisiae)
    Hs.9925  [show with all ESTs]
    Unigene Representative Sequence: NM_017956
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000521443 ENST00000522518 ENST00000328599(uc003yra.4)
    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TRMT12:
    hsa-miR-629* hsa-miR-32* hsa-miR-450b-5p
    SwitchGear 3'UTR luciferase reporter plasmidTRMT12 3' UTR sequence
    Inhib. RNA
    Products:
         
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    GenScript: all cDNA clones in your preferred vector: TRMT12 (NM_017956)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRMT12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRMT12
    Sirion Biotech Customized lentivirus for stable overexpression of TRMT12 
                         Customized lentivirus expression plasmids for stable overexpression of TRMT12 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRMT12
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRMT12

    Additional mRNA sequence: 

    AK000779.1 AK222727.1 AK225083.1 BC003057.2 BC011713.2 

    3 DOTS entries:

    DT.456135  DT.121488314  DT.97795533 

    24/69 AceView cDNA sequences (see all 69):

    BC003057 BM128389 BM472116 AA305469 AW470700 BQ013767 AI768622 BX089632 
    AI624916 BU956459 CR592089 BM450240 BE549275 AA595233 BU742646 AW197704 
    BQ223922 BE276231 AW468601 AL582936 CF272203 BC011713 BQ212865 N71278 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRMT12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TRMT12 Expression
    About this image


    See TRMT12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRMT12

    SOURCE GeneReport for Unigene cluster: Hs.9925
        SABiosciences Custom PCR Arrays for TRMT12
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRMT12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TRMT12 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trmt121 , 5 tRNA methyltranferase 12 homolog (S. cerevisiae)5
    tRNA methyltranferase 121
    82.53(n)1
    81.38(a)1
      15 (25.09 cM)5
    682601  NM_026642.21  NP_080918.21 
     588726495 
    chicken
    (Gallus gallus)
    Aves TRMT121 tRNA methyltransferase 12 homolog (S. cerevisiae) 64.42(n)
    62.25(a)
      422259  XM_420244.3  XP_420244.3 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.38912 Transcribed sequence with weak similarity to protein more 74.36(n)    BX771664.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005354041 tRNA wybutosine-synthesizing protein 2 homolog 54.88(n)
    51.91(a)
      100535404  XM_003199929.1  XP_003199977.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F40F9.106
    Protein F40F9.10
    23(a)
    1 ↔ 1
    V(9711464-9713632)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TRM12(YML005W)4 S-adenosylmethionine-dependent methyltransferase of more   --   13(260221-261609) 855008  NP_013709.1 


    ENSEMBL Gene Tree for TRMT12 (if available)
    TreeFam Gene Tree for TRMT12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRMT12 gene

    TRMT12 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TRMT12
    PGOHUM00000241464


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/120 SNPs in TRMT12 are shown (see all 120)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1129512981,2
    C,F--125461066(+) TAGCTC/AGTTCA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1816843251,2
    --125461080(+) AAAAGG/TTCTTG 1 -- us2k10--------
    rs1150018941,2
    F--125461204(+) ACTCCC/TCAGGA 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs286683861,2
    F--125461247(+) TGGGTT/CACAGA 1 -- us2k1 tfbs31Minor allele frequency- C:0.09WA 118
    rs78129111,2
    C,F,A,H--125461287(+) gtttcC/Ttactg 1 -- us2k120Minor allele frequency- T:0.47NS EA NA WA CSA 878
    rs1841023011,2
    --125461308(+) GTTCAC/TCCCAT 1 -- us2k10--------
    rs1470296911,2
    --125461404(+) TTTCAC/TTTGCA 1 -- us2k10--------
    rs1151266481,2
    F--125461534(+) TTGCAA/GAGGGA 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1164182711,2
    C--125461559(+) TTCTGG/TTACTT 1 -- us2k10--------
    rs1155481051,2
    C,F--125461611(+) GAAGTC/TAGTGT 1 -- us2k11Minor allele frequency- T:0.06WA 118

    HapMap Linkage Disequilibrium report for TRMT12 (125463048 - 125474391 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TRMT12:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv7874n71CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TRMT12
    DNA2.0 Custom Variant and Variant Library Synthesis for TRMT12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611244    OMIM disorders: --

    2 diseases for TRMT12:    About MalaCards
    noma    breast cancer


    TRMT12 for disorders           About GeneDecksing


    Export disorders for TRMT12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRMT12 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TRMT12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis. (PubMed id 17150819)1, 3 Noma A. and Suzuki T. (2006)
    2. A novel methyltransferase required for the formation of the hypermodified nucleoside wybutosine in eucaryotic tRNA. (PubMed id 16005430)1, 3 Kalhor H.R....Clarke S. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Chromosome 8 BAC array comparative genomic hybridization and expression analysis identify amplification and overexpression of TRMT12 in breast cancer. (PubMed id 17440925)1 Rodriguez V....Chandrasekharappa S. (2007)
    6. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55039 HGNC: 26091 AceView: FLJ20772 Ensembl:ENSG00000183665 euGenes: HUgn55039
    ECgene: TRMT12 H-InvDB: TRMT12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRMT12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRMT12 gene:
    Search GeneIP for patents involving TRMT12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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