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Aliases for TRMT10B Gene

Aliases for TRMT10B Gene

  • TRNA Methyltransferase 10 Homolog B (S. Cerevisiae) 2 3
  • RNA (Guanine-9-)-Methyltransferase Domain-Containing Protein 3 3 4
  • RNA (Guanine-9-) Methyltransferase Domain Containing 3 2 3
  • RG9MTD3 3 4
  • TRNA Methyltransferase 10 Homolog B 3
  • EC 2.1.1.- 4
  • BA3J10.9 3

External Ids for TRMT10B Gene

Previous Symbols for TRMT10B Gene

  • RG9MTD3

Summaries for TRMT10B Gene

GeneCards Summary for TRMT10B Gene

TRMT10B (TRNA Methyltransferase 10 Homolog B (S. Cerevisiae)) is a Protein Coding gene. GO annotations related to this gene include methyltransferase activity. An important paralog of this gene is TRMT10C.

UniProtKB/Swiss-Prot for TRMT10B Gene

  • Probable RNA methyltransferase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRMT10B Gene

Genomics for TRMT10B Gene

Genomic Location for TRMT10B Gene

Start:
37,753,800 bp from pter
End:
37,778,972 bp from pter
Size:
25,173 bases
Orientation:
Plus strand

Genomic View for TRMT10B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRMT10B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRMT10B Gene

No data available for Regulatory Elements for TRMT10B Gene

Proteins for TRMT10B Gene

  • Protein details for TRMT10B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PF06-TM10B_HUMAN
    Recommended name:
    tRNA methyltransferase 10 homolog B
    Protein Accession:
    Q6PF06
    Secondary Accessions:
    • B7Z216
    • B7Z3D3
    • Q05DJ4
    • Q5QP83
    • Q8NAG2
    • Q96N36

    Protein attributes for TRMT10B Gene

    Size:
    316 amino acids
    Molecular mass:
    36124 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB71074.1; Type=Erroneous termination; Positions=317; Note=Translated as stop.; Evidence={ECO:0000305};

    Alternative splice isoforms for TRMT10B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TRMT10B Gene

Proteomics data for TRMT10B Gene at MOPED

Post-translational modifications for TRMT10B Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRMT10B Gene

Domains for TRMT10B Gene

Protein Domains for TRMT10B Gene

UniProtKB/Swiss-Prot:

TM10B_HUMAN
Domain:
  • Contains 1 SAM-dependent MTase TRM10-type domain.:
    • Q6PF06
Family:
  • Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.:
    • Q6PF06
genes like me logo Genes that share domains with TRMT10B: view

No data available for Gene Families for TRMT10B Gene

Function for TRMT10B Gene

Molecular function for TRMT10B Gene

UniProtKB/Swiss-Prot Function: Probable RNA methyltransferase.

Enzyme Numbers (IUBMB) for TRMT10B Gene

Gene Ontology (GO) - Molecular Function for TRMT10B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008168 methyltransferase activity IEA --
genes like me logo Genes that share ontologies with TRMT10B: view

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRMT10B Gene

Localization for TRMT10B Gene

No data available for Gene Ontology (GO) - Cellular Components for TRMT10B Gene

Pathways for TRMT10B Gene

SuperPathways for TRMT10B Gene

No Data Available

Interacting Proteins for TRMT10B Gene

Gene Ontology (GO) - Biological Process for TRMT10B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032259 methylation IEA --
genes like me logo Genes that share ontologies with TRMT10B: view

No data available for Pathways by source for TRMT10B Gene

Transcripts for TRMT10B Gene

Unigene Clusters for TRMT10B Gene

TRNA methyltransferase 10 homolog B (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TRMT10B Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10
SP1: -
SP2: - - - - - - - -
SP3: - - - -
SP4: - - - -
SP5: - -
SP6: - - -
SP7: - -
SP8: -

Relevant External Links for TRMT10B Gene

GeneLoc Exon Structure for
TRMT10B
ECgene alternative splicing isoforms for
TRMT10B

Expression for TRMT10B Gene

mRNA expression in normal human tissues for TRMT10B Gene

SOURCE GeneReport for Unigene cluster for TRMT10B Gene Hs.655614

genes like me logo Genes that share expressions with TRMT10B: view

Orthologs for TRMT10B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TRMT10B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RG9MTD3 37
  • 100 (a)
OneToOne
TRMT10B 36
  • 99.89 (n)
  • 99.68 (a)
cow
(Bos Taurus)
Mammalia TRMT10B 36
  • 88.71 (n)
  • 85.76 (a)
TRMT10B 37
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TRMT10B 36
  • 90.51 (n)
  • 87.34 (a)
TRMT10B 37
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Trmt10b 36
  • 82.33 (n)
  • 78.41 (a)
Trmt10b 16
Trmt10b 37
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TRMT10B 37
  • 66 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TRMT10B 37
  • 62 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Trmt10b 36
  • 81.1 (n)
  • 78.03 (a)
chicken
(Gallus gallus)
Aves LOC768672 36
  • 61.36 (n)
  • 59.47 (a)
TRMT10B 37
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TRMT10B 37
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100493764 36
  • 68.12 (n)
  • 69.93 (a)
Str.616 36
zebrafish
(Danio rerio)
Actinopterygii trmt10b 36
  • 60.47 (n)
  • 58.1 (a)
trmt10b 37
  • 50 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F25H8.1 37
  • 24 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TRM10 37
  • 20 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 45 (a)
OneToOne
Species with no ortholog for TRMT10B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TRMT10B Gene

ENSEMBL:
Gene Tree for TRMT10B (if available)
TreeFam:
Gene Tree for TRMT10B (if available)

Paralogs for TRMT10B Gene

Paralogs for TRMT10B Gene

Pseudogenes.org Pseudogenes for TRMT10B Gene

genes like me logo Genes that share paralogs with TRMT10B: view

Variants for TRMT10B Gene

Sequence variations from dbSNP and Humsavar for TRMT10B Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs9858 -- 37,774,679(-) AGGAT(A/T)AAACT intron-variant
rs725687 -- 37,755,887(+) GTTTA(A/G)GTAAA intron-variant
rs764224 -- 37,760,995(+) CACTT(C/T)TGAGG intron-variant
rs764225 -- 37,760,691(+) CACTA(G/T)AGGTG intron-variant
rs764226 -- 37,760,648(+) TAATT(A/C)CCAAA intron-variant

Relevant External Links for TRMT10B Gene

HapMap Linkage Disequilibrium report
TRMT10B

No data available for Structural Variations from Database of Genomic Variants (DGV) for TRMT10B Gene

Disorders for TRMT10B Gene

No disorders were found for TRMT10B Gene.

No data available for UniProtKB/Swiss-Prot for TRMT10B Gene

Publications for TRMT10B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  3. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TRMT10B Gene

Sources for TRMT10B Gene

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