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Aliases for TRIQK Gene

Aliases for TRIQK Gene

  • Triple QxxK/R Motif Containing 2 3 5
  • Triple Repetitive-Sequence Of QXXK/R Protein Homolog 3 4
  • C8orf83 3 4
  • Triple QxxK/R Motif-Containing Protein 3
  • Chromosome 8 Open Reading Frame 83 2
  • Protein TRIQK 3
  • PRO0845 3
  • UPF0599 3

External Ids for TRIQK Gene

Previous HGNC Symbols for TRIQK Gene

  • C8orf83

Previous GeneCards Identifiers for TRIQK Gene

  • GC08M093896

Summaries for TRIQK Gene

GeneCards Summary for TRIQK Gene

TRIQK (Triple QxxK/R Motif Containing) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TRIQK Gene

  • May play a role in cell growth and maintenance of cell morphology.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIQK Gene

Genomics for TRIQK Gene

Regulatory Elements for TRIQK Gene

Enhancers for TRIQK Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G092963 1.1 ENCODE 7.6 +52.3 52337 2.8 HDGF PKNOX1 FOXA2 CREB3L1 ARID4B SIN3A DMAP1 ZBTB7B YY1 SLC30A9 TRIQK IRF5P1 ENSG00000253197
GH08G093050 0.4 ENCODE 11.7 -33.0 -32989 0.8 SMARCA4 EP300 TRIQK ENSG00000253197 FLJ46284 MIR8084 GC08P093115
GH08G092605 0.9 ENCODE dbSUPER 4.9 +411.5 411493 1.8 HDAC1 TAL1 CEBPB CEBPG ATF2 ARID1B E2F1 TCF12 GATA3 POLR2A TRIQK LOC102724710 LOC105375639
GH08G092805 0.4 ENCODE 4.7 +214.2 214246 0.2 FOXP2 TRIQK ENSG00000253577 GC08P092864
GH08G092951 0.5 FANTOM5 1.7 +66.1 66106 0.3 CBX5 GLIS1 TRIQK IRF5P1 ENSG00000253197
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRIQK on UCSC Golden Path with GeneCards custom track

Genomic Location for TRIQK Gene

Chromosome:
8
Start:
92,883,530 bp from pter
End:
93,017,673 bp from pter
Size:
134,144 bases
Orientation:
Minus strand

Genomic View for TRIQK Gene

Genes around TRIQK on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIQK Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIQK Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIQK Gene

Proteins for TRIQK Gene

  • Protein details for TRIQK Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q629K1-TRIQK_HUMAN
    Recommended name:
    Triple QxxK/R motif-containing protein
    Protein Accession:
    Q629K1

    Protein attributes for TRIQK Gene

    Size:
    86 amino acids
    Molecular mass:
    9683 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIQK Gene

Post-translational modifications for TRIQK Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TRIQK Gene

Domains & Families for TRIQK Gene

Protein Domains for TRIQK Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TRIQK Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q629K1

UniProtKB/Swiss-Prot:

TRIQK_HUMAN :
  • Belongs to the TRIQK family.
Family:
  • Belongs to the TRIQK family.
genes like me logo Genes that share domains with TRIQK: view

No data available for Gene Families for TRIQK Gene

Function for TRIQK Gene

Molecular function for TRIQK Gene

UniProtKB/Swiss-Prot Function:
May play a role in cell growth and maintenance of cell morphology.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TRIQK Gene

Localization for TRIQK Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRIQK Gene

Endoplasmic reticulum membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TRIQK gene
Compartment Confidence
endoplasmic reticulum 3
mitochondrion 2
cytosol 2
plasma membrane 1
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for TRIQK Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TRIQK: view

Pathways & Interactions for TRIQK Gene

SuperPathways for TRIQK Gene

No Data Available

Interacting Proteins for TRIQK Gene

Gene Ontology (GO) - Biological Process for TRIQK Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRIQK Gene

Drugs & Compounds for TRIQK Gene

No Compound Related Data Available

Transcripts for TRIQK Gene

Unigene Clusters for TRIQK Gene

Triple QxxK/R motif containing:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIQK Gene

No ASD Table

Relevant External Links for TRIQK Gene

GeneLoc Exon Structure for
TRIQK
ECgene alternative splicing isoforms for
TRIQK

Expression for TRIQK Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRIQK Gene

Protein differential expression in normal tissues from HIPED for TRIQK Gene

This gene is overexpressed in Bone (17.8), Adrenal (12.6), and Pancreas (11.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TRIQK Gene



NURSA nuclear receptor signaling pathways regulating expression of TRIQK Gene:

TRIQK

SOURCE GeneReport for Unigene cluster for TRIQK Gene:

Hs.440643

Evidence on tissue expression from TISSUES for TRIQK Gene

  • Liver(4.2)
  • Nervous system(3.8)
genes like me logo Genes that share expression patterns with TRIQK: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRIQK Gene

Orthologs for TRIQK Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIQK Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRIQK 34 35
  • 100 (n)
cow
(Bos Taurus)
Mammalia TRIQK 34 35
  • 92.64 (n)
mouse
(Mus musculus)
Mammalia Triqk 34 16 35
  • 90.31 (n)
rat
(Rattus norvegicus)
Mammalia Triqk 34
  • 87.6 (n)
dog
(Canis familiaris)
Mammalia TRIQK 34
  • 82.95 (n)
oppossum
(Monodelphis domestica)
Mammalia TRIQK 35
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves TRIQK 35
  • 79 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TRIQK 35
  • 74 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii triqk 34 35
  • 63.1 (n)
Species where no ortholog for TRIQK was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIQK Gene

ENSEMBL:
Gene Tree for TRIQK (if available)
TreeFam:
Gene Tree for TRIQK (if available)

Paralogs for TRIQK Gene

No data available for Paralogs for TRIQK Gene

Variants for TRIQK Gene

Sequence variations from dbSNP and Humsavar for TRIQK Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000024676 -- 92,943,832(+) AAAAA(C/T)AGACG intron-variant
rs1000032715 -- 92,900,726(+) TGAGG(A/C)TTTTT intron-variant
rs1000094811 -- 92,945,189(+) ACTTG(A/C)CCAAT intron-variant
rs1000104421 -- 92,929,575(+) ACTGC(C/T)TGGAA intron-variant, utr-variant-5-prime
rs1000133063 -- 92,908,125(+) GTTCA(A/C)TTCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRIQK Gene

Variant ID Type Subtype PubMed ID
dgv1215e201 CNV deletion 23290073
esv2737305 CNV deletion 23290073
esv2737306 CNV deletion 23290073
esv2737309 CNV deletion 23290073
nsv1022473 CNV loss 25217958
nsv1146317 CNV insertion 26484159
nsv520321 CNV gain 19592680

Relevant External Links for TRIQK Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRIQK

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TRIQK Gene

Disorders for TRIQK Gene

Relevant External Links for TRIQK

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRIQK

No disorders were found for TRIQK Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIQK Gene

Publications for TRIQK Gene

  1. TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates. (PMID: 18828657) Onuma Y. … Whitman M. (Zool. Sci. 2008) 2 3 4 64
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for TRIQK Gene

Sources for TRIQK Gene

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