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Aliases for TRIQK Gene

Aliases for TRIQK Gene

  • Triple QxxK/R Motif Containing 2 3
  • Triple Repetitive-Sequence Of QXXK/R Protein Homolog 3 4
  • C8orf83 3 4
  • Triple QxxK/R Motif-Containing Protein 3
  • Chromosome 8 Open Reading Frame 83 2
  • Protein TRIQK 3
  • PRO0845 3
  • UPF0599 3

External Ids for TRIQK Gene

Previous HGNC Symbols for TRIQK Gene

  • C8orf83

Previous GeneCards Identifiers for TRIQK Gene

  • GC08M093896

Summaries for TRIQK Gene

GeneCards Summary for TRIQK Gene

TRIQK (Triple QxxK/R Motif Containing) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TRIQK Gene

  • May play a role in cell growth and maintenance of cell morphology.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIQK Gene

Genomics for TRIQK Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TRIQK Gene

Start:
92,883,530 bp from pter
End:
93,017,673 bp from pter
Size:
134,144 bases
Orientation:
Minus strand

Genomic View for TRIQK Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIQK Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIQK Gene

No data available for Regulatory Elements for TRIQK Gene

Proteins for TRIQK Gene

  • Protein details for TRIQK Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q629K1-TRIQK_HUMAN
    Recommended name:
    Triple QxxK/R motif-containing protein
    Protein Accession:
    Q629K1
    Secondary Accessions:

    Protein attributes for TRIQK Gene

    Size:
    86 amino acids
    Molecular mass:
    9683 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIQK Gene

Proteomics data for TRIQK Gene at MOPED

Post-translational modifications for TRIQK Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRIQK Gene

Domains for TRIQK Gene

Protein Domains for TRIQK Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q629K1

UniProtKB/Swiss-Prot:

TRIQK_HUMAN :
  • Belongs to the TRIQK family.
Family:
  • Belongs to the TRIQK family.
genes like me logo Genes that share domains with TRIQK: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TRIQK Gene

Function for TRIQK Gene

Molecular function for TRIQK Gene

UniProtKB/Swiss-Prot Function:
May play a role in cell growth and maintenance of cell morphology.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIQK Gene

Localization for TRIQK Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRIQK Gene

Endoplasmic reticulum membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TRIQK Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TRIQK: view

No data available for Subcellular locations from COMPARTMENTS for TRIQK Gene

Pathways for TRIQK Gene

SuperPathways for TRIQK Gene

No Data Available

Interacting Proteins for TRIQK Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000368138%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000368138 for TRIQK Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for TRIQK Gene

None

No data available for Pathways by source for TRIQK Gene

Transcripts for TRIQK Gene

Unigene Clusters for TRIQK Gene

Triple QxxK/R motif containing:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIQK

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIQK Gene

No ASD Table

Relevant External Links for TRIQK Gene

GeneLoc Exon Structure for
TRIQK
ECgene alternative splicing isoforms for
TRIQK

Expression for TRIQK Gene

mRNA expression in normal human tissues for TRIQK Gene

Protein differential expression in normal tissues for TRIQK Gene

This gene is overexpressed in Bone (17.8), Adrenal (12.6), and Pancreas (11.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TRIQK Gene

SOURCE GeneReport for Unigene cluster for TRIQK Gene Hs.440643

genes like me logo Genes that share expressions with TRIQK: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for TRIQK Gene

Orthologs for TRIQK Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIQK Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TRIQK 35
  • 92.64 (n)
  • 94.19 (a)
TRIQK 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TRIQK 35
  • 82.95 (n)
  • 80.23 (a)
mouse
(Mus musculus)
Mammalia Triqk 35
  • 90.31 (n)
  • 88.37 (a)
Triqk 16
Triqk 36
  • 88 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TRIQK 35
  • 100 (n)
  • 100 (a)
TRIQK 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Triqk 35
  • 87.6 (n)
  • 89.53 (a)
oppossum
(Monodelphis domestica)
Mammalia TRIQK 36
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves TRIQK 36
  • 79 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TRIQK 36
  • 74 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii triqk 35
  • 63.1 (n)
  • 67.86 (a)
triqk 36
  • 68 (a)
OneToOne
Species with no ortholog for TRIQK:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIQK Gene

ENSEMBL:
Gene Tree for TRIQK (if available)
TreeFam:
Gene Tree for TRIQK (if available)

Paralogs for TRIQK Gene

No data available for Paralogs for TRIQK Gene

Variants for TRIQK Gene

Sequence variations from dbSNP and Humsavar for TRIQK Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs138955090 -- 92,899,914(+) CATTC(A/G)TTCTT intron-variant
rs139063163 -- 92,891,598(+) ATTAC(A/G)TAATT intron-variant
rs139201809 -- 92,953,709(+) GAAGA(C/T)GAAAT intron-variant
rs138937338 -- 92,964,744(+) GTGGA(C/T)CATTA intron-variant
rs138876860 -- 92,929,373(+) AAATA(A/G)GAAAA intron-variant

Relevant External Links for TRIQK Gene

HapMap Linkage Disequilibrium report
TRIQK

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TRIQK Gene

Disorders for TRIQK Gene

No disorders were found for TRIQK Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TRIQK Gene

Publications for TRIQK Gene

  1. TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates. (PMID: 18828657) Onuma Y. … Whitman M. (Zool. Sci. 2008) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3

Products for TRIQK Gene

Sources for TRIQK Gene

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