TRIQK Gene
protein-coding GIFtS: 31
GCID: GC08M093896
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triple QxxK/R motif containing(Previous name: chromosome 8 open reading frame 83 )
(Previous symbol: C8orf83)
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Aliases
for TRIQK gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Triple QxxK/R Motif Containing1 2 | | LOC2861441 | | C8orf831 2 3 | | Chromosome 8 Open Reading Frame 831 | | PRO08451 2 | | UPF05992 | | Triple Repetitive-Sequence Of QXXK/R Protein Homolog2 3 | | Protein TRIQK2 | | DKFZp779L10681 | | Triple QxxK/R Motif-Containing Protein2 |
Export aliases for TRIQK gene to outside databases |
Summaries
for TRIQK gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: TRIQK_HUMAN, Q629K1Function: May play a role in cell growth and maintenance of cell morphology (By similarity)
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Genomic Views
for TRIQK gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008046.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TRIQK
Other transcription factors
Search SABiosciences Chromatin IP Primers for TRIQK
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIQK |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q22.1 Ensembl cytogenetic band: 8q22.1 HGNC cytogenetic band: 8q22.1TRIQK Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M093896: view genomic region
(about GC identifiers)
Start:
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93,895,758 bp from pter |
End:
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94,029,901 bp from pter |
Size:
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134,144 bases |
Orientation:
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minus strand |
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Proteins
for TRIQK gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TRIQK_HUMAN, Q629K1 (See
protein sequence)Recommended Name: Triple QxxK/R motif-containing protein Size: 86 amino acids; 9683 Da
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane proteinExplore the universe of human proteins at neXtProt for TRIQK: NX_Q629K1
TRIQK Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (7 alternative transcripts):
NP_001165266.1 NP_001165267.1 NP_001165268.1 NP_001165269.1 NP_001165270.1 NP_001177964.1 NP_001177965.1
ENSEMBL proteins: ENSP00000429517 ENSP00000430837 ENSP00000430915 ENSP00000429822 ENSP00000428822 ENSP00000428759 ENSP00000368138 ENSP00000427850 ENSP00000430992 ENSP00000428757 ENSP00000429742 ENSP00000429381 ENSP00000430683 ENSP00000430123 ENSP00000429302 ENSP00000442030
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005789 | endoplasmic reticulum membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
TRIQK for ontologies About GeneDecksing
TRIQK Antibody Products:
Assay Products for TRIQK: |
Protein
Domains /
Families
for TRIQK gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TRIQK for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q629K1ProtoNet protein and cluster: Q629K1 UniProtKB/Swiss-Prot: TRIQK_HUMAN, Q629K1Similarity: Belongs to the TRIQK family |
Function
for TRIQK gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TRIQK_HUMAN, Q629K1Function: May play a role in cell growth and maintenance of cell morphology (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIQK (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIQK (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for TRIQK | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRIQK | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIQK |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIQK |
|
Pathways & Interactions
for TRIQK gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIQK
|
Drugs & Compounds
for TRIQK gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TRIQK
Search CenterWatch for drugs/clinical trials and news about TRIQK
|
Transcripts
for TRIQK gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TRIQK gene (7 alternative transcripts): NM_001171795.1 NM_001171796.1 NM_001171797.1 NM_001171798.1 NM_001171799.1 NM_001191035.1 NM_001191036.1 Unigene Cluster for TRIQK: Triple QxxK/R motif containing Hs.440643 [show with all ESTs]Unigene Representative Sequence: NM_00117179618/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000521988(uc022axy.1 uc022axz.1 uc003yfn.4 uc003yfk.4 uc010map.3 uc003yfq.4 uc022aya.1 uc003yfr.4)
ENST00000518748 ENST00000523580 ENST00000520686 ENST00000520430 ENST00000517858
ENST00000517540 ENST00000378861 ENST00000524037 ENST00000521617 ENST00000518400
ENST00000520384 ENST00000519069 ENST00000524107 ENST00000519969 ENST00000517751
ENST00000522925 ENST00000522903
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIQK (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIQK (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for TRIQK | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRIQK | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIQK |
Additional cDNA sequence: AF130048.2 AK096398.1 AK097956.1 BC031029.1 BC065838.1 BC104254.1 BC104255.1 BC110326.1 BC113007.1 BC113008.1 CR749421.1 DQ351291.1 15 DOTS entries: DT.444331 DT.100798569 DT.91746338 DT.99935818 DT.97842764 DT.121482459 DT.100798571 DT.91746337 DT.100798568 DT.441957 DT.100718751 DT.121482465 DT.121482484 DT.91746332 DT.100798570 24/191 AceView cDNA sequences (see all 191): CA424893 CA848822 CR598592 AF130048 BQ574120 BC031029 AI692541 AI334186 AW468514 CR602063 AI924905 AA236570 AI888438 BM558912 BQ014917 AA362987 BU683830 CN481345 AI431851 CB156093 CR606814 AI400735 BQ067164 BM462105
GeneLoc Exon Structure
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Expression
for TRIQK gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
See TRIQK Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TRIQK
SOURCE GeneReport for Unigene cluster: Hs.440643
SABiosciences Custom PCR Arrays for TRIQK
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIQK
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TRIQK | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIQK | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIQK | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIQK |
Orthologs
for TRIQK gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TRIQK gene from 4/9 species (see all 9) About this table
ENSEMBL Gene Tree for TRIQK (if available)
TreeFam Gene Tree for TRIQK (if available) |
Paralogs
for TRIQK gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TRIQK gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TRIQK (93895758 - 94029901 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TRIQK: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIQK |
|
Disorders
/ Diseases
for TRIQK gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TRIQK gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TRIQK gene integrated from 9 sources:
(articles sorted by number of sources associating them with TRIQK) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates. (PubMed id 18828657)1, 2, 3 Onuma Y....Whitman M. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for TRIQK gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing TRIQK gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TRIQK gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TRIQK gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TRIQK | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for TRIQK gene:
Search GeneIP for patents involving TRIQK
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TRIQK gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIQK | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIQK | | | OriGene Protein Over-expression Lysate for TRIQK | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIQK | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIQK | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TRIQK | | OriGene Custom Protein Services for TRIQK | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRIQK | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIQK | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIQK | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIQK | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIQK | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIQK |
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 |  |  |  | |
| | | | Search Tocris compounds for TRIQK |
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 | | | TRIQK Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIQK |
|  |  |  | | | | Search ThermoFisher Antibodies for TRIQK |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIQK |
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