Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TRIP12 Gene

Aliases for TRIP12 Gene

  • Thyroid Hormone Receptor Interactor 12 2 3 5
  • HECT-Type E3 Ubiquitin Transferase TRIP12 3 4
  • E3 Ubiquitin-Protein Ligase For Arf 3 4
  • TR-Interacting Protein 12 3 4
  • TRIP-12 3 4
  • ULF 3 4
  • Probable E3 Ubiquitin-Protein Ligase TRIP12 3
  • Thyroid Receptor Interacting Protein 12 3
  • Thyroid Receptor-Interacting Protein 12 4
  • E3 Ubiquitin-Protein Ligase TRIP12 3
  • EC 2.3.2.26 4
  • KIAA0045 4

External Ids for TRIP12 Gene

Previous GeneCards Identifiers for TRIP12 Gene

  • GC02M228692
  • GC02M229363
  • GC02M230595
  • GC02M230834
  • GC02M230457
  • GC02M230340
  • GC02M222471

Summaries for TRIP12 Gene

Entrez Gene Summary for TRIP12 Gene

  • The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]

GeneCards Summary for TRIP12 Gene

TRIP12 (Thyroid Hormone Receptor Interactor 12) is a Protein Coding gene. Diseases associated with TRIP12 include Chronic Inflammation Of Lacrimal Passage and Acute Inflammation Of Lacrimal Passage. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include binding and ubiquitin-protein transferase activity. An important paralog of this gene is HECTD1.

UniProtKB/Swiss-Prot for TRIP12 Gene

  • E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardeless of the presence of lysine residues in target proteins. In normal cells, mediates ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A, a lysine-less tumor suppressor required for p53/TP53 activation under oncogenic stress. In cancer cells, however, isoform p19ARF/ARF and TRIP12 are located in different cell compartments, preventing isoform p19ARF/ARF ubiquitination and degradation. Does not mediate ubiquitination of isoform p16-INK4a of CDKN2A. Also catalyzes ubiquitination of NAE1 and SMARCE1, leading to their degradation. Ubiquitination and degradation of target proteins is regulated by interaction with proteins such as MYC, TRADD or SMARCC1, which disrupt the interaction between TRIP12 and target proteins. Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of Lys-63-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spreading of ubiquitinated chromatin at damaged chromosomes.

Gene Wiki entry for TRIP12 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIP12 Gene

Genomics for TRIP12 Gene

Regulatory Elements for TRIP12 Gene

Enhancers for TRIP12 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G230599 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.7 -678.5 -678514 5.1 HDGF PKNOX1 FOXA2 CREB3L1 MLX AGO1 ZFP64 ARID4B SIN3A DMAP1 TRIP12 SLC16A14 SP140 SP110 SP140L GPR55 SP100 GC02P230588 LINC01907
GH02G230711 1.1 ENCODE 11 -790.6 -790575 5.3 HDGF FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 YBX1 ZNF2 RNU6-268P TRIP12 PSMD1 CAB39 DNER BANF1P3
GH02G230755 1.2 Ensembl ENCODE 10 -834.4 -834415 4.7 PKNOX1 FOXA2 ZNF493 ZFP64 YBX1 BMI1 ZNF155 ZNF138 FOS RELB FBXO36 SLC16A14 CAB39 TEX44 TRIP12 RNU6-451P RNU6-268P GC02P230779
GH02G230797 1 ENCODE 10.7 -874.6 -874564 0.6 ATF1 PKNOX1 CREB3L1 E2F7 SIN3A YY1 ELK1 ZNF143 ZNF207 ZNF263 RPL28P2 RNU6-268P CAB39 TRIP12 SPATA3 SPATA3-AS1 GC02P230779 ENSG00000270891
GH02G229919 1.6 Ensembl ENCODE dbSUPER 6 +1.7 1708 4.7 HNRNPUL1 PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 SLC30A9 FBXO36 TRIP12 RNU6-613P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRIP12 on UCSC Golden Path with GeneCards custom track

Promoters for TRIP12 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000131622 1539 3801 HNRNPUL1 PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 SLC30A9

Genomic Location for TRIP12 Gene

Chromosome:
2
Start:
229,763,837 bp from pter
End:
229,923,239 bp from pter
Size:
159,403 bases
Orientation:
Minus strand

Genomic View for TRIP12 Gene

Genes around TRIP12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIP12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIP12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIP12 Gene

Proteins for TRIP12 Gene

  • Protein details for TRIP12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14669-TRIPC_HUMAN
    Recommended name:
    E3 ubiquitin-protein ligase TRIP12
    Protein Accession:
    Q14669
    Secondary Accessions:
    • D4HL82
    • Q14CA3
    • Q14CF1
    • Q15644
    • Q53R87
    • Q53TE7

    Protein attributes for TRIP12 Gene

    Size:
    1992 amino acids
    Molecular mass:
    220434 Da
    Quaternary structure:
    • Interacts with MYC; leading to disrupt interaction with isoform p19ARF/ARF of CDKN2A. Interacts with TRADD; leading to disrupt interaction with isoform p19ARF/ARF of CDKN2A. Interacts with SMARCC1; leading to disrupt interaction with SMARCE1.
    SequenceCaution:
    • Sequence=AAY14681.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAY14755.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAA05837.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for TRIP12 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TRIP12 Gene

Post-translational modifications for TRIP12 Gene

  • Ubiquitination at Lys259, posLast=298298, Lys355, isoforms=2, 3, 41038, Lys1048, Lys1221, Lys1259, posLast=12881288, Lys1600, posLast=16611661, posLast=16681668, and isoforms=2, 3, 41941
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for TRIP12 Gene

Domains & Families for TRIP12 Gene

Protein Domains for TRIP12 Gene

Suggested Antigen Peptide Sequences for TRIP12 Gene

Graphical View of Domain Structure for InterPro Entry

Q14669

UniProtKB/Swiss-Prot:

TRIPC_HUMAN :
  • Belongs to the UPL family. K-HECT subfamily.
Family:
  • Belongs to the UPL family. K-HECT subfamily.
genes like me logo Genes that share domains with TRIP12: view

No data available for Gene Families for TRIP12 Gene

Function for TRIP12 Gene

Molecular function for TRIP12 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
UniProtKB/Swiss-Prot Function:
E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardeless of the presence of lysine residues in target proteins. In normal cells, mediates ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A, a lysine-less tumor suppressor required for p53/TP53 activation under oncogenic stress. In cancer cells, however, isoform p19ARF/ARF and TRIP12 are located in different cell compartments, preventing isoform p19ARF/ARF ubiquitination and degradation. Does not mediate ubiquitination of isoform p16-INK4a of CDKN2A. Also catalyzes ubiquitination of NAE1 and SMARCE1, leading to their degradation. Ubiquitination and degradation of target proteins is regulated by interaction with proteins such as MYC, TRADD or SMARCC1, which disrupt the interaction between TRIP12 and target proteins. Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of Lys-63-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spreading of ubiquitinated chromatin at damaged chromosomes.

Enzyme Numbers (IUBMB) for TRIP12 Gene

Gene Ontology (GO) - Molecular Function for TRIP12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity TAS,IEA --
GO:0005515 protein binding IPI 18627766
GO:0016740 transferase activity IEA --
GO:0046966 thyroid hormone receptor binding IDA 7776974
genes like me logo Genes that share ontologies with TRIP12: view
genes like me logo Genes that share phenotypes with TRIP12: view

Animal Models for TRIP12 Gene

MGI Knock Outs for TRIP12:

Animal Model Products

  • Taconic Biosciences Mouse Models for TRIP12

CRISPR Products

Inhibitory RNA Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TRIP12 Gene

Localization for TRIP12 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRIP12 Gene

Nucleus, nucleoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TRIP12 gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 1
mitochondrion 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TRIP12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA,IEA 21630459
GO:0005654 nucleoplasm IDA,IEA 20208519
GO:0005829 cytosol TAS --
GO:0016607 nuclear speck IDA --
genes like me logo Genes that share ontologies with TRIP12: view

Pathways & Interactions for TRIP12 Gene

genes like me logo Genes that share pathways with TRIP12: view

UniProtKB/Swiss-Prot Q14669-TRIPC_HUMAN

  • Pathway: Protein modification; protein ubiquitination.

Gene Ontology (GO) - Biological Process for TRIP12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000209 protein polyubiquitination TAS --
GO:0006281 DNA repair IEA --
GO:0006974 cellular response to DNA damage stimulus IMP 22884692
GO:0009790 embryo development ISS,IEA --
GO:0016567 protein ubiquitination IEA --
genes like me logo Genes that share ontologies with TRIP12: view

No data available for SIGNOR curated interactions for TRIP12 Gene

Drugs & Compounds for TRIP12 Gene

(3) Drugs for TRIP12 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Adenosine monophosphate Approved Nutra 0
Adenosine triphosphate Approved Nutra 0

(1) Additional Compounds for TRIP12 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
pyrophosphate
  • (4-)Diphosphoric acid ion
  • (P2O74-)Diphosphate
  • Diphosphate
  • Diphosphoric acid
  • PPi
14000-31-8
genes like me logo Genes that share compounds with TRIP12: view

Transcripts for TRIP12 Gene

Unigene Clusters for TRIP12 Gene

Thyroid hormone receptor interactor 12:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIP12 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19a · 19b ^ 20a ·
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9: -
SP10:
SP11:
SP12:
SP13:
SP14: - - -
SP15: - - -
SP16: - -
SP17:
SP18:
SP19:
SP20: - - - - -
SP21: - - - -
SP22: - -
SP23:

ExUns: 20b · 20c ^ 21a · 21b ^ 22a · 22b ^ 23 ^ 24 ^ 25a · 25b ^ 26 ^ 27 ^ 28 ^ 29a · 29b ^ 30a · 30b · 30c ^ 31a · 31b ^ 32 ^ 33a · 33b ^ 34a · 34b · 34c ^
SP1:
SP2: -
SP3: - -
SP4: -
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13: -
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:

ExUns: 35a · 35b ^ 36 ^ 37 ^ 38a · 38b ^ 39a · 39b ^ 40 ^ 41 ^ 42 ^ 43
SP1:
SP2:
SP3:
SP4:
SP5: -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:

Relevant External Links for TRIP12 Gene

GeneLoc Exon Structure for
TRIP12
ECgene alternative splicing isoforms for
TRIP12

Expression for TRIP12 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRIP12 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TRIP12 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (23.5) and Lymph node (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TRIP12 Gene



Protein tissue co-expression partners for TRIP12 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TRIP12 Gene:

TRIP12

SOURCE GeneReport for Unigene cluster for TRIP12 Gene:

Hs.591633

Evidence on tissue expression from TISSUES for TRIP12 Gene

  • Liver(4.4)
  • Bone marrow(4.3)
  • Nervous system(3.9)
  • Heart(3.1)
  • Muscle(2.3)
  • Spleen(2.1)
genes like me logo Genes that share expression patterns with TRIP12: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRIP12 Gene

Orthologs for TRIP12 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TRIP12 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRIP12 34 35
  • 99.7 (n)
dog
(Canis familiaris)
Mammalia TRIP12 34 35
  • 94.45 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 94 (a)
OneToMany
-- 35
  • 92 (a)
OneToMany
cow
(Bos Taurus)
Mammalia TRIP12 35 34
  • 93.49 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TRIP12 35
  • 93 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Trip12 34
  • 92.64 (n)
mouse
(Mus musculus)
Mammalia Trip12 16 35 34
  • 92.62 (n)
chicken
(Gallus gallus)
Aves TRIP12 34 35
  • 85.47 (n)
lizard
(Anolis carolinensis)
Reptilia TRIP12 35
  • 89 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia trip12 34
  • 79.19 (n)
Str.9526 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.12932 34
zebrafish
(Danio rerio)
Actinopterygii trip12 34 35
  • 72.97 (n)
Dr.16497 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10944 34
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001296 34
  • 55.58 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG17735 36
  • 55 (a)
ctrip 35
  • 15 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UFD4 35 37
  • 24 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons KAK 34
  • 46.94 (n)
rice
(Oryza sativa)
Liliopsida Os02g0101700 34
  • 49.37 (n)
Os.28066 34
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9340 35
  • 49 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4507 34
Species where no ortholog for TRIP12 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIP12 Gene

ENSEMBL:
Gene Tree for TRIP12 (if available)
TreeFam:
Gene Tree for TRIP12 (if available)

Paralogs for TRIP12 Gene

Paralogs for TRIP12 Gene

genes like me logo Genes that share paralogs with TRIP12: view

Variants for TRIP12 Gene

Sequence variations from dbSNP and Humsavar for TRIP12 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs193921087 Uncertain significance 229,858,949(-) CCAGC(A/C)CCAGA intron-variant, reference, missense
rs1000017238 -- 229,922,449(+) TTTGG(C/T)CCCTT intron-variant, upstream-variant-2KB
rs1000024289 -- 229,916,823(+) ATTTT(A/T)AAAAA intron-variant
rs1000034276 -- 229,855,010(+) TGTAA(A/T)CCCAG intron-variant
rs1000055648 -- 229,874,256(+) CTTTT(C/T)CCCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRIP12 Gene

Variant ID Type Subtype PubMed ID
dgv164e55 CNV gain 17911159
dgv4179n100 CNV gain 25217958
dgv7330n54 CNV gain 21841781
esv2751841 CNV gain 17911159
esv3575337 CNV gain 25503493
esv3594581 CNV gain 21293372
esv3594583 CNV loss 21293372
esv3594584 CNV loss 21293372
esv3594585 CNV gain 21293372
nsv1004285 CNV gain 25217958
nsv1008431 CNV gain 25217958
nsv3200 CNV insertion 18451855
nsv460118 CNV gain 19166990
nsv584649 CNV gain 21841781
nsv584650 CNV gain 21841781
nsv998132 CNV gain 25217958

Variation tolerance for TRIP12 Gene

Residual Variation Intolerance Score: 0.578% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.53; 29.69% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRIP12 Gene

Human Gene Mutation Database (HGMD)
TRIP12
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRIP12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIP12 Gene

Disorders for TRIP12 Gene

MalaCards: The human disease database

(4) MalaCards diseases for TRIP12 Gene - From: DISEASES and GeneCards

- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for TRIP12

Genetic Association Database (GAD)
TRIP12
Human Genome Epidemiology (HuGE) Navigator
TRIP12
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRIP12
genes like me logo Genes that share disorders with TRIP12: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TRIP12 Gene

Publications for TRIP12 Gene

  1. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. (PMID: 7776974) Lee J.W. … Moore D.D. (Mol. Endocrinol. 1995) 2 3 4 64
  2. TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation. (PMID: 22561347) Chio I.I. … Mak T.W. (Nat. Cell Biol. 2012) 3 4 64
  3. TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes. (PMID: 22884692) Gudjonsson T. … Lukas C. (Cell 2012) 3 4 64
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
  5. Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses. (PMID: 20208519) Chen D. … Gu W. (Nature 2010) 3 4 64

Products for TRIP12 Gene

Sources for TRIP12 Gene

Content
Loading form....