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Aliases for TRIM77 Gene

Aliases for TRIM77 Gene

  • Tripartite Motif Containing 77 2 3
  • Tripartite Motif Containing 77, Pseudogene 2 3
  • TRIM77P 3 4
  • Putative Tripartite Motif-Containing Protein 64D 3
  • Putative Tripartite Motif-Containing Protein 77 3
  • Tripartite Motif-Containing Protein 77 3
  • Tripartite Motif-Containing 77 2
  • TRIM77-Isoform 3

External Ids for TRIM77 Gene

Previous HGNC Symbols for TRIM77 Gene

  • TRIM77P

Previous GeneCards Identifiers for TRIM77 Gene

  • GC11P089085
  • GC11U901242
  • GC11P089445
  • GC11P085680

Summaries for TRIM77 Gene

GeneCards Summary for TRIM77 Gene

TRIM77 (Tripartite Motif Containing 77) is a Protein Coding gene. An important paralog of this gene is TRIM64C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM77 Gene

Genomics for TRIM77 Gene

Genomic Location for TRIM77 Gene

Start:
89,710,299 bp from pter
End:
89,717,872 bp from pter
Size:
7,574 bases
Orientation:
Plus strand

Genomic View for TRIM77 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIM77 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM77 Gene

No data available for Regulatory Elements for TRIM77 Gene

Proteins for TRIM77 Gene

  • Protein details for TRIM77 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    I1YAP6-TRI77_HUMAN
    Recommended name:
    Tripartite motif-containing protein 77
    Protein Accession:
    I1YAP6
    Secondary Accessions:

    Protein attributes for TRIM77 Gene

    Size:
    450 amino acids
    Molecular mass:
    52450 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM77 Gene

Proteomics data for TRIM77 Gene at MOPED

Post-translational modifications for TRIM77 Gene

No Post-translational modifications

Other Protein References for TRIM77 Gene

No data available for DME Specific Peptides for TRIM77 Gene

Domains for TRIM77 Gene

Gene Families for TRIM77 Gene

HGNC:
  • RNF :RING-type (C3HC4) zinc fingers
  • TRIM :Tripartite motif containing / Tripartite motif containing

Graphical View of Domain Structure for InterPro Entry

I1YAP6

UniProtKB/Swiss-Prot:

TRI77_HUMAN :
  • I1YAP6
Domain:
  • Contains 1 B30.2/SPRY domain.
Family:
  • Belongs to the TRIM/RBCC family.
Similarity:
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM77: view

No data available for Suggested Antigen Peptide Sequences for TRIM77 Gene

Function for TRIM77 Gene

Gene Ontology (GO) - Molecular Function for TRIM77 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with TRIM77: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRIM77 Gene

Localization for TRIM77 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRIM77 Gene COMPARTMENTS Subcellular localization image for TRIM77 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for TRIM77 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM77: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRIM77 Gene

Pathways for TRIM77 Gene

SuperPathways for TRIM77 Gene

No Data Available

Interacting Proteins for TRIM77 Gene

Gene Ontology (GO) - Biological Process for TRIM77 Gene

None

No data available for Pathways by source for TRIM77 Gene

Transcripts for TRIM77 Gene

mRNA/cDNA for TRIM77 Gene

(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM77 Gene

No ASD Table

Relevant External Links for TRIM77 Gene

GeneLoc Exon Structure for
TRIM77
ECgene alternative splicing isoforms for
TRIM77

Expression for TRIM77 Gene

mRNA expression in normal human tissues for TRIM77 Gene

SOURCE GeneReport for Unigene cluster for TRIM77 Gene Hs.723112

genes like me logo Genes that share expressions with TRIM77: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for TRIM77 Gene

Orthologs for TRIM77 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM77 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 44 (a)
ManyToMany
TRIM77P 35
  • 99.63 (n)
  • 99.56 (a)
cow
(Bos Taurus)
Mammalia RNF18 36
  • 61 (a)
OneToOne
TRIM77P 35
  • 75.85 (n)
  • 60.89 (a)
dog
(Canis familiaris)
Mammalia LOC485141 35
  • 76.89 (n)
  • 62.44 (a)
TRIM77 36
  • 62 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 33 (a)
ManyToMany
-- 36
  • 26 (a)
ManyToMany
-- 36
  • 25 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 18 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 25 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 15 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 24 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 16 (a)
ManyToMany
-- 36
  • 21 (a)
ManyToMany
-- 36
  • 20 (a)
ManyToMany
-- 36
  • 22 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii trim109 36
  • 16 (a)
ManyToMany
Species with no ortholog for TRIM77:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM77 Gene

ENSEMBL:
Gene Tree for TRIM77 (if available)
TreeFam:
Gene Tree for TRIM77 (if available)

Paralogs for TRIM77 Gene

Selected SIMAP similar genes for TRIM77 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TRIM77: view

Variants for TRIM77 Gene

Sequence variations from dbSNP and Humsavar for TRIM77 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1967074 -- 89,714,145(-) TTTTA(C/T)TCTTT intron-variant
rs1967075 -- 89,714,088(-) AAATA(C/T)AGTTT intron-variant
rs1967076 -- 89,712,420(-) ATTCC(A/C)CCACT intron-variant
rs2634261 -- 89,709,440(-) AAAGT(A/G)TATAA upstream-variant-2KB
rs2634262 -- 89,709,296(-) AATAA(A/G)ACTGG upstream-variant-2KB

Relevant External Links for TRIM77 Gene

HapMap Linkage Disequilibrium report
TRIM77

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TRIM77 Gene

Disorders for TRIM77 Gene

No disorders were found for TRIM77 Gene.

No data available for UniProtKB/Swiss-Prot for TRIM77 Gene

Publications for TRIM77 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4
  2. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K. … Sawyer S.L. (PLoS Genet. 2011) 3 4
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for TRIM77 Gene

Sources for TRIM77 Gene

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