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Aliases for TRIM77 Gene

Aliases for TRIM77 Gene

  • Tripartite Motif Containing 77 2 3 5
  • Tripartite Motif Containing 77, Pseudogene 2 3
  • TRIM77P 3 4
  • Putative Tripartite Motif-Containing Protein 64D 3
  • Putative Tripartite Motif-Containing Protein 77 3
  • Tripartite Motif-Containing Protein 77 3
  • Tripartite Motif-Containing 77 2
  • TRIM77-Isoform 3

External Ids for TRIM77 Gene

Previous HGNC Symbols for TRIM77 Gene

  • TRIM77P

Previous GeneCards Identifiers for TRIM77 Gene

  • GC11P089085
  • GC11U901242
  • GC11P089445
  • GC11P085680

Summaries for TRIM77 Gene

GeneCards Summary for TRIM77 Gene

TRIM77 (Tripartite Motif Containing 77) is a Protein Coding gene. An important paralog of this gene is TRIM43.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM77 Gene

Genomics for TRIM77 Gene

Genomic Location for TRIM77 Gene

Chromosome:
11
Start:
89,710,299 bp from pter
End:
89,717,872 bp from pter
Size:
7,574 bases
Orientation:
Plus strand

Genomic View for TRIM77 Gene

Genes around TRIM77 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM77 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM77 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM77 Gene

No data available for Regulatory Elements for TRIM77 Gene

Proteins for TRIM77 Gene

  • Protein details for TRIM77 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    I1YAP6-TRI77_HUMAN
    Recommended name:
    Tripartite motif-containing protein 77
    Protein Accession:
    I1YAP6

    Protein attributes for TRIM77 Gene

    Size:
    450 amino acids
    Molecular mass:
    52450 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM77 Gene

Post-translational modifications for TRIM77 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM77 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM77 Gene

Domains & Families for TRIM77 Gene

Gene Families for TRIM77 Gene

Graphical View of Domain Structure for InterPro Entry

I1YAP6

UniProtKB/Swiss-Prot:

TRI77_HUMAN :
  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 1 B box-type zinc finger.
Domain:
  • Contains 1 B30.2/SPRY domain.
Family:
  • Belongs to the TRIM/RBCC family.
Similarity:
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM77: view

No data available for Suggested Antigen Peptide Sequences for TRIM77 Gene

Function for TRIM77 Gene

Gene Ontology (GO) - Molecular Function for TRIM77 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with TRIM77: view

Phenotypes for TRIM77 Gene

GenomeRNAi human phenotypes for TRIM77:
genes like me logo Genes that share phenotypes with TRIM77: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIM77 Gene

Localization for TRIM77 Gene

Gene Ontology (GO) - Cellular Components for TRIM77 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM77: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TRIM77 Gene

Pathways & Interactions for TRIM77 Gene

SuperPathways for TRIM77 Gene

No Data Available

Interacting Proteins for TRIM77 Gene

Gene Ontology (GO) - Biological Process for TRIM77 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRIM77 Gene

Transcripts for TRIM77 Gene

mRNA/cDNA for TRIM77 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM77 Gene

No ASD Table

Relevant External Links for TRIM77 Gene

GeneLoc Exon Structure for
TRIM77
ECgene alternative splicing isoforms for
TRIM77

Expression for TRIM77 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRIM77 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRIM77 Gene:

TRIM77

SOURCE GeneReport for Unigene cluster for TRIM77 Gene:

Hs.723112
genes like me logo Genes that share expression patterns with TRIM77: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRIM77 Gene

Orthologs for TRIM77 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM77 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRIM77P 34
  • 99.63 (n)
-- 35
  • 44 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia LOC485141 34
  • 76.89 (n)
TRIM77 35
  • 62 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TRIM77P 34
  • 75.85 (n)
RNF18 35
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 33 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 26 (a)
ManyToMany
-- 35
  • 25 (a)
ManyToMany
-- 35
  • 25 (a)
ManyToMany
-- 35
  • 24 (a)
ManyToMany
-- 35
  • 24 (a)
ManyToMany
-- 35
  • 18 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 15 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 29 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 24 (a)
ManyToMany
-- 35
  • 22 (a)
ManyToMany
-- 35
  • 21 (a)
ManyToMany
-- 35
  • 20 (a)
ManyToMany
-- 35
  • 16 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii trim109 35
  • 16 (a)
ManyToMany
Species where no ortholog for TRIM77 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM77 Gene

ENSEMBL:
Gene Tree for TRIM77 (if available)
TreeFam:
Gene Tree for TRIM77 (if available)

Paralogs for TRIM77 Gene

(14) SIMAP similar genes for TRIM77 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for TRIM77 Gene

genes like me logo Genes that share paralogs with TRIM77: view

Variants for TRIM77 Gene

Sequence variations from dbSNP and Humsavar for TRIM77 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10765235 -- 89,708,512(+) caccc(A/G)tgtcc upstream-variant-2KB
rs10765236 -- 89,716,862(+) TTTGC(A/G)AAAAT intron-variant
rs10830353 -- 89,710,147(+) TGTTG(C/T)ACTGT upstream-variant-2KB
rs10830354 -- 89,710,168(+) CCATC(C/T)TATTT upstream-variant-2KB
rs10830355 -- 89,710,261(+) CATGG(A/G)GGAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TRIM77 Gene

Variant ID Type Subtype PubMed ID
dgv1250n100 CNV loss 25217958
esv2759849 CNV gain+loss 17122850
esv2762931 CNV gain 21179565
esv32702 CNV gain+loss 17666407
esv3579993 CNV gain 25503493
esv3627177 CNV loss 21293372
esv3627178 CNV gain 21293372
esv3892057 CNV gain 25118596
nsv1043643 CNV gain 25217958
nsv1052092 CNV gain 25217958
nsv468785 CNV gain 19166990
nsv555770 CNV gain 21841781
nsv975214 CNV duplication 23825009
nsv983050 CNV duplication 23825009

Variation tolerance for TRIM77 Gene

Gene Damage Index Score: 3.70; 57.37% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRIM77 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRIM77

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM77 Gene

Disorders for TRIM77 Gene

Relevant External Links for TRIM77

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRIM77

No disorders were found for TRIM77 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM77 Gene

Publications for TRIM77 Gene

  1. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K. … Sawyer S.L. (PLoS Genet. 2011) 3 4 64
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 64

Products for TRIM77 Gene

Sources for TRIM77 Gene

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