Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TRIM7 Gene

protein-coding   GIFtS: 48
GCID: GC05M180620

Tripartite Motif Containing 7

(Previous name: tripartite motif-containing 7)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Tripartite Motif Containing 71 2     RNF902 3
Glycogenin-Interacting Protein1 2 3     RING Finger Protein 902 3
GNIP2 3 5     Tripartite Motif-Containing 71
Tripartite Motif Protein TRIM71 2     Tripartite Motif-Containing Protein 72

External Ids:    HGNC: 162781   Entrez Gene: 817862   Ensembl: ENSG000001460547   OMIM: 6093155   UniProtKB: Q9C0293   

Export aliases for TRIM7 gene to outside databases

Previous GC identifers: GC05M180671 GC05P181733 GC05M180683 GC05M180739 GC05M180732 GC05M180553 GC05M175348


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for TRIM7 Gene:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to
both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis.
Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jul 2013)

GeneCards Summary for TRIM7 Gene:
TRIM7 (tripartite motif containing 7) is a protein-coding gene. Diseases associated with TRIM7 include precocious puberty, and endotheliitis. An important paralog of this gene is TRIM4.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000005.10  NT_023133.14  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRIM7 gene promoter:
         AREB6   FAC1   Sp1   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TRIM7 promoter sequence
   Search Chromatin IP Primers for TRIM7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

TRIM7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM7 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M180620:  view genomic region     (about GC identifiers)

Start:
180,620,924 bp from pter      End:
180,632,293 bp from pter
Size:
11,370 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TRIM7_HUMAN, Q9C029 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 7  
Size: 511 amino acids; 56631 Da
Subunit: Forms homodimers and heterodimers. Interacts with GYG and DES
Secondary accessions: A2RUE4 D3DWR7 Q969F5 Q96F67 Q96J89 Q96J90
Alternative splicing: 4 isoforms:  Q9C029-2   Q9C029-3   Q9C029-4   Q9C029-1   

Explore the universe of human proteins at neXtProt for TRIM7: NX_Q9C029

Explore proteomics data for TRIM7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRIM7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_203128.1  NP_976038.1  NP_976039.1  NP_976040.1  NP_976041.1  NP_976042.1  

    ENSEMBL proteins: 
     ENSP00000274773   ENSP00000376994   ENSP00000391458   ENSP00000334666   ENSP00000376991  
     ENSP00000355059  

    TRIM7 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TRIM7
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TRIM7
    GenScript Custom Purified and Recombinant Proteins Services for TRIM7
    Novus Biologicals TRIM7 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRIM7

    TRIM7 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for TRIM7
    OriGene Custom Antibody Services for TRIM7
    Novus Biologicals TRIM7 Antibodies
    Abcam antibodies for TRIM7
    Cloud-Clone Corp. Antibodies for TRIM7
    ThermoFisher Antibodies for TRIM7
    LSBio Antibodies in human, mouse, rat for TRIM7

    TRIM7 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TRIM7
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TRIM7
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TRIM7
    Cloud-Clone Corp. CLIAs for TRIM7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    Selected InterPro protein domains (see all 11):
     IPR006574 PRY
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR001870 B30.2/SPRY
     IPR020457 Znf_B-box_chordata

    Graphical View of Domain Structure for InterPro Entry Q9C029

    ProtoNet protein and cluster: Q9C029

    4 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger
    IPB003879 Butyrophylin C-terminal DUF signature
    IPB006574 SPRY-associated domain


    UniProtKB/Swiss-Prot: TRIM7_HUMAN, Q9C029
    Domain: The B30.2 domain mediates interaction with GYG. The coiled-coil region mediates homodimerization and
    heterodimerization
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 RING-type zinc finger


    TRIM7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    TRIM7 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIM7
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TRIM7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRIM7
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRIM7

    miRNA
    Products:
        
    miRTarBase miRNAs that target TRIM7:
    hsa-mir-124-3p (MIRT022939)

    Block miRNA regulation of human, mouse, rat TRIM7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TRIM7 (see all 9):
    hsa-miR-607 hsa-miR-125a-5p hsa-miR-1271 hsa-miR-125b hsa-miR-670 hsa-miR-145 hsa-miR-96 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidTRIM7 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TRIM7
    Predesigned siRNA for gene silencing in human, mouse, rat TRIM7

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TRIM7

    Clone
    Products:
         
    OriGene clones in human, mouse for TRIM7 (see all 33)
    OriGene ORF clones in mouse, rat for TRIM7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 6): TRIM7 (NM_033342)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM7

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TRIM7
    Browse ESI BIO Cell Lines and PureStem Progenitors for TRIM7 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA11331580
    GO:0005737cytoplasm IDA11331580
    GO:0043231intracellular membrane-bounded organelle ----

    TRIM7 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRIM7
    Interactions:

        Search GeneGlobe Interaction Network for TRIM7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for TRIM7 (Q9C0293 ENSP000002747734) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DESP176613, ENSP000003630714I2D: score=1 STRING: ENSP00000363071
    GYG1P469763, ENSP000003407364I2D: score=2 STRING: ENSP00000340736
    RB1ENSP000002671634STRING: ENSP00000267163
    UBE2D1ENSP000003630194STRING: ENSP00000363019
    UBE2D2ENSP000003817174STRING: ENSP00000381717
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRIM7



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TRIM7 gene (6 alternative transcripts): 
    NM_033342.3  NM_203293.2  NM_203294.1  NM_203295.1  NM_203296.1  NM_203297.1  

    Unigene Cluster for TRIM7:

    Tripartite motif containing 7
    Hs.487412  [show with all ESTs]
    Unigene Representative Sequence: NM_203297
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000274773(uc003mmz.1) ENST00000504241 ENST00000393319(uc003mmv.1)
    ENST00000422067 ENST00000509199 ENST00000334421(uc003mna.2) ENST00000393315(uc003mmy.1)
    ENST00000361809(uc003mmw.1 uc003mmx.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TRIM7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TRIM7 (see all 9):
    hsa-miR-607 hsa-miR-125a-5p hsa-miR-1271 hsa-miR-125b hsa-miR-670 hsa-miR-145 hsa-miR-96 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidTRIM7 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TRIM7
    Predesigned siRNA for gene silencing in human, mouse, rat TRIM7
    Clone
    Products:
         
    OriGene clones in human, mouse for TRIM7 (see all 33)
    OriGene ORF clones in mouse, rat for TRIM7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 6): TRIM7 (NM_033342)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM7
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM7
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM7
      QuantiTect SYBR Green Assays in human, mouse, rat TRIM7
      QuantiFast Probe-based Assays in human, mouse, rat TRIM7

    Additional mRNA sequence: 

    AF220032.1 AF396651.1 AF396652.1 AF396653.1 AF396654.1 AF396655.1 AK314872.1 BC011567.1 
    BC080553.1 BC132863.1 BC132867.1 

    8 DOTS entries:

    DT.104824  DT.91747128  DT.434212  DT.97828106  DT.97811527  DT.97828107  DT.97779939  DT.101975279 

    Selected AceView cDNA sequences (see all 61):

    NM_203295 NM_203296 F36995 AI380945 AI347404 AF396651 AI492496 NM_203294 
    AW015471 BC080553 BF000049 NM_203293 NM_203297 AX776005 NM_033342 BM970007 
    BE676872 F25118 BX110649 BI084394 AF396654 AI139356 AK124617 BF000691 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TRIM7 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7
    SP1:        -     -     -           -     -                           
    SP2:                    -           -     -                           
    SP3:                    -                 -                           
    SP4:                                -     -                           
    SP5:        -     -     -                                             


    ECgene alternative splicing isoforms for TRIM7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TRIM7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TRIM7 Expression
    About this image


    TRIM7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     NULL (Uncategorized)
             CD31, CD144 positive cells
     
     Endothelium (Cardiovascular System)
             Human umbilical vein endothelial cells (HUVEC)
     
     Colon (Gastrointestinal Tract)
    TRIM7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRIM7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.487412

    UniProtKB/Swiss-Prot: TRIM7_HUMAN, Q9C029
    Tissue specificity: Skeletal muscle and placenta, at lower levels in heart, brain and pancreas. Isoform 1 is
    widely expressed with high level in testis, kidney and heart

        Custom PCR Arrays for TRIM7
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM7
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM7
    QuantiTect SYBR Green Assays in human, mouse, rat TRIM7
    QuantiFast Probe-based Assays in human, mouse, rat TRIM7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TRIM7 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim71 , 5 tripartite motif-containing 71, 5 86.58(n)1
    92.74(a)1
      11 (28.80 cM)5
    940891  NM_053166.21  NP_444396.21 
     488261405 
    chicken
    (Gallus gallus)
    Aves TRIM71 tripartite motif containing 7 64.75(n)
    56.19(a)
      417040  NM_001099352.1  NP_001092822.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRIM76
    tripartite motif containing 7
    50(a)
    1 ↔ 1
    2(188920089-188939659)


    ENSEMBL Gene Tree for TRIM7 (if available)
    TreeFam Gene Tree for TRIM7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TRIM7 gene
    TRIM42  TRIM392  TRIM342  TRIML12  TRIM272  TRIM582  TRIM682  TRIM602  
    TRIM222  TRIM172  TRIM52  TRIM62  TRIM6-TRIM342  TRIM212  TRIM382  TRIM112  
    TRIM39-RPP212  
    13 SIMAP similar genes for TRIM7 using alignment to 1 protein entry:     TRIM7_HUMAN:
    TRIM39R    TRIM10    TRIM27    TRIM39    TRIM15    ZNFB7
    TRIM11    TRIM58    TRIM21    TRIM41    MEFV    TRIM68
    TRIM75

    TRIM7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TRIM7 (see all 211)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs345481581,2
    C--180630909(+) CCCCC-/CACCAG 5 -- int1 ut510--------
    rs352266431,2
    C--180633502(+) CGTTA-/ATCAAA 2 -- us2k10--------
    rs1893659231,2
    --180837822(+) CCTCTG/TGGATA 5 -- ds50010--------
    rs744673641,2
    C--180837871(+) GAGCTC/TGAAGC 5 -- ds50010--------
    rs783188131,2
    C--180837872(+) AGCTTG/TAAGCA 5 -- ds50010--------
    rs755653071,2
    C--180837873(+) GCTTGA/GAGCAC 5 -- ds50010--------
    rs1179209251,2
    C,F--180837989(+) TCCGAG/ATCTGG 5 -- ds50011Minor allele frequency- A:0.03EA 120
    rs2544611,2
    C,F,A,H--180838027(-) CTCTCA/GCTACC 5 -- ds500128Minor allele frequency- G:0.43NS EA NA WA CSA 2779
    rs1444146801,2
    --180838097(+) ATAGGC/GTATGA 5 -- ds50010--------
    rs1181274201,2
    C,F--180838125(+) TGTTTG/ACAACA 5 -- ds50011Minor allele frequency- A:0.03EA 120

    HapMap Linkage Disequilibrium report for TRIM7 (180620924 - 180632293 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for TRIM7:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv517697CNV Loss19592680
    dgv6408n71CNV Loss21882294
    nsv883310CNV Loss21882294
    nsv830567CNV Loss17160897
    nsv462591CNV Loss19166990
    dgv6409n71CNV Loss21882294
    nsv428133CNV Gain18775914
    dgv735n27CNV Gain19166990
    nsv883305CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM7
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 609315    OMIM disorders: --

    2 diseases for TRIM7:    
    About MalaCards
    precocious puberty    endotheliitis


    TRIM7 for disorders           About GeneDecksing


    Export disorders for TRIM7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TRIM7 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with TRIM7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The tripartite motif family identifies cell compartments. (PubMed id 11331580)1, 2, 3 Reymond A.... Ballabio A. (EMBO J. 2001)
    2. Structure-function analysis of GNIP, the glycogenin-interacting protein. (PubMed id 14984203)1, 2 Zhai L.... Roach P.J. (Arch. Biochem. Biophys. 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. GNIP, a novel protein that binds and activates glycogenin, the self- glucosylating initiator of glycogen biosynthesis. (PubMed id 11916970)1, 2 Skurat A.V.... Roach P.J. (J. Biol. Chem. 2002)
    5. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    6. Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7. (PubMed id 21940674)1 Liang Q.... Zhu F. (J. Immunol. 2011)
    7. Functional interactions between ubiquitin E2 enzymes and TRIM proteins. (PubMed id 21143188)1 Napolitano L.M....Meroni G. (Biochem. J. 2011)
    8. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PubMed id 18854154)1 KAPnig R....Chanda S.K. (Cell 2008)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H.... Kim N.S. (Mamm. Genome 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 81786 HGNC: 16278 AceView: TRIM7 Ensembl:ENSG00000146054 euGenes: HUgn81786
    ECgene: TRIM7 H-InvDB: TRIM7

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TRIM7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TRIM7 gene:
    Search GeneIP for patents involving TRIM7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for TRIM7   OriGene RNAi products in human, mouse, rat for TRIM7  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TRIM7  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TRIM7  
     OriGene qSTAR qPCR primer pairs in human, mouse for TRIM7   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TRIM7   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TRIM7   OriGene Custom Protein Services for TRIM7  

     
     
     Block miRNA regulation of human, mouse, rat TRIM7 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TRIM7
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM7 Predesigned siRNA for gene silencing in human, mouse, rat TRIM7
     QuantiFast Probe-based Assays in human, mouse, rat TRIM7 QuantiTect SYBR Green Assays in human, mouse, rat TRIM7
     Custom PCR Arrays for TRIM7 Search Chromatin IP Primers for TRIM7
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM7  Search GeneGlobe Interaction Network for TRIM7
     Regulatory tfbs in TRIM7 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TRIM7 GenScript cDNA clones with any tag delivered in your preferred vector for TRIM7
     GenScript Custom Assay Services for TRIM7 GenScript Custom overexpressing Cell Line Services for TRIM7
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TRIM7
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TRIM7 antibodies
     TRIM7 lysates
     Antibodies for TRIM7
     See all of Abcam's Antibodies, Kits and Proteins for TRIM7
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TRIM7
     Antibodies for TRIM7
     ELISAs for TRIM7
     CLIAs for TRIM7



     Browse ESI BIO Cell Lines and PureStem Progenitors for TRIM7
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM7
     SwitchGear 3'UTR luciferase reporter plasmids for TRIM7
     SwitchGear Promoter luciferase reporter plasmids for TRIM7
     ThermoFisher Antibodies for TRIM7
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM7
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIM7
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TRIM7
     LSBio Antibodies in human, mouse, rat for TRIM7
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TRIM7 gene at Home site.
    Version: 3.12.164 25 Aug 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4