Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRIM7 Gene

protein-coding   GIFtS: 47
GCID: GC05M180620

tripartite motif containing 7

(Previous name: tripartite motif-containing 7 )
 Explore 1 disease affiliated with
TRIM7 via our new
 Human Malady Compendium 
Biological research products
for TRIM7
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Tripartite Motif Containing 71 2     Glycogenin-Interacting Protein2 3
GNIP1 2 3 5     RING Finger Protein 902 3
RNF901 2 3     Tripartite Motif Protein TRIM72
Tripartite Motif-Containing 71 2     Tripartite Motif-Containing Protein 72

External Ids:    HGNC: 162781   Entrez Gene: 817862   Ensembl: ENSG000001460547   OMIM: 6093155   UniProtKB: Q9C0293   

Export aliases for TRIM7 gene to outside databases

Previous GC identifers: GC05M180671 GC05P181733 GC05M180683 GC05M180739 GC05M180732 GC05M180553 GC05M175348


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRIM7:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both
the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Multiple
transcript variants have been found for this gene, and some of them encode the same isoform. (provided by RefSeq, Jul
2008)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_023133.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRIM7 gene promoter:
         AREB6   FAC1   Sp1   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TRIM7 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRIM7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

TRIM7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM7 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M180620:  view genomic region     (about GC identifiers)

Start:
180,620,924 bp from pter      End:
180,632,293 bp from pter
Size:
11,370 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TRIM7_HUMAN, Q9C029 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 7  
Size: 511 amino acids; 56631 Da
Subunit: Forms homodimers and heterodimers. Interacts with GYG and DES
Secondary accessions: A2RUE4 D3DWR7 Q969F5 Q96F67 Q96J89 Q96J90
Alternative splicing: 4 isoforms:  Q9C029-2   Q9C029-3   Q9C029-4   Q9C029-1   

Explore the universe of human proteins at neXtProt for TRIM7: NX_Q9C029

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9C029

  • TRIM7 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (6 alternative transcripts): 
    NP_203128.1  NP_976038.1  NP_976039.1  NP_976040.1  NP_976041.1  NP_976042.1  

    ENSEMBL proteins: 
     ENSP00000274773   ENSP00000376994   ENSP00000391458   ENSP00000334666   ENSP00000376991  
     ENSP00000355059  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate (see all 2): TRIM7
    OriGene Custom Protein Services for TRIM7 
    GenScript Custom Purified and Recombinant Proteins Services for TRIM7
    Novus Biologicals TRIM7 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TRIM7

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0043231intracellular membrane-bounded organelle IDA--


    TRIM7 for ontologies           About GeneDecksing



    TRIM7 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies: TRIM7
    OriGene Custom Antibody Services for TRIM7 
    GenScript Custom Superior Antibodies Services for TRIM7
    Novus Biologicals TRIM7 Antibody
    Search for Antibodies for TRIM7 at Abcam  
    Uscn Antibodies for TRIM7
    ThermoFisher Antibodies for TRIM7

    Assay Products for TRIM7: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TRIM7
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for TRIM7


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TRIM7 for domains           About GeneDecksing

    5/11 InterPro domains/families (see all 11):
     IPR006574 PRY
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR001870 B30.2/SPRY
     IPR020457 Znf_B-box_chordata

    Graphical View of Domain Structure for InterPro Entry Q9C029

    ProtoNet protein and cluster: Q9C029

    4 Blocks protein families:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger
    IPB003879 Butyrophylin C-terminal DUF signature
    IPB006574 SPRY-associated domain


    UniProtKB/Swiss-Prot: TRIM7_HUMAN, Q9C029
    Domain: The B30.2 domain mediates interaction with GYG. The coiled-coil region mediates homodimerization and
    heterodimerization
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 RING-type zinc finger


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 6): TRIM7
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM7
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM7 (see all 9):
    hsa-miR-607 hsa-miR-125a-5p hsa-miR-1271 hsa-miR-125b hsa-miR-670 hsa-miR-145 hsa-miR-96 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidTRIM7 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIM7 (see all 4)
    OriGene shRNA RFP: TRIM7
    OriGene siRNA: TRIM7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM7

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TRIM7

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM7 (see all 7)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM7 (see all 6)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 6): TRIM7 (NM_033342)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM7 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TRIM7
    Search LifeMap BioReagents cell lines for TRIM7

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM7

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--


    TRIM7 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIM7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/7 Interacting proteins for TRIM7 (Q9C0293 ENSP000002747734) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DESP176613, ENSP000003630714I2D: score=1 STRING: ENSP00000363071
    GYG1P469763, ENSP000003407364I2D: score=2 STRING: ENSP00000340736
    RB1ENSP000002671634STRING: ENSP00000267163
    UBE2D1ENSP000003630194STRING: ENSP00000363019
    UBE2D2ENSP000003817174STRING: ENSP00000381717
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRIM7
    Search CenterWatch for drugs/clinical trials and news about TRIM7 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRIM7 gene (6 alternative transcripts): 
    NM_033342.2  NM_203293.1  NM_203294.1  NM_203295.1  NM_203296.1  NM_203297.1  

    Unigene Cluster for TRIM7:

    Tripartite motif containing 7
    Hs.487412  [show with all ESTs]
    Unigene Representative Sequence: NM_203297
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000274773(uc003mmz.1) ENST00000504241 ENST00000393319(uc003mmv.1)
    ENST00000422067 ENST00000509199 ENST00000334421(uc003mna.2) ENST00000393315(uc003mmy.1)
    ENST00000361809(uc003mmw.1 uc003mmx.1)

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 6): TRIM7
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM7
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM7 (see all 9):
    hsa-miR-607 hsa-miR-125a-5p hsa-miR-1271 hsa-miR-125b hsa-miR-670 hsa-miR-145 hsa-miR-96 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidTRIM7 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIM7 (see all 4)
    OriGene shRNA RFP: TRIM7
    OriGene siRNA: TRIM7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM7
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM7 (see all 7)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM7 (see all 6)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 6): TRIM7 (NM_033342)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM7 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIM7
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRIM7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM7

    Additional cDNA sequence: 

    AF220032.1 AF396651.1 AF396652.1 AF396653.1 AF396654.1 AF396655.1 AK314872.1 BC011567.1 
    BC080553.1 BC132863.1 BC132867.1 

    8 DOTS entries:

    DT.104824  DT.91747128  DT.434212  DT.97828106  DT.97811527  DT.97828107  DT.97779939  DT.101975279 

    24/61 AceView cDNA sequences (see all 61):

    NM_203297 F36995 AW015471 NM_203294 F25118 AX776005 NM_203293 BX110649 
    BE676872 BM970007 AI380945 AI492496 AF396651 NM_203295 NM_033342 BF000049 
    AI347404 NM_203296 BC080553 BC011567 BM825056 F19336 AI566529 AF220032 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TRIM7 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7
    SP1:        -     -     -           -     -                           
    SP2:                    -           -     -                           
    SP3:                    -                 -                           
    SP4:                                -     -                           
    SP5:        -     -     -                                             


    ECgene alternative splicing isoforms for TRIM7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRIM7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    TRIM7 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneMaxillary ProcessBone
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    CD31, CD144 positive cells (Two-step protocol fo...)

    See TRIM7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRIM7

    SOURCE GeneReport for Unigene cluster: Hs.487412

    UniProtKB/Swiss-Prot: TRIM7_HUMAN, Q9C029
    Tissue specificity: Skeletal muscle and placenta, at lower levels in heart, brain and pancreas. Isoform 1 is widely
    expressed with high level in testis, kidney and heart

        SABiosciences Custom PCR Arrays for TRIM7
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIM7
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRIM7
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM7
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TRIM7 gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves TRIM71 tripartite motif-containing 7 64.57(n)
    55.87(a)
      417040  NM_001099352.1  NP_001092822.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRIM76
    --
    (see all 33)
    --
    52(a)
    38(a)
    (see all 33)
    1 ↔ 1
    possible ortholog
    (see all 33)
    2(188920221-188937195)
    2(188851296-188862893)
    zebrafish
    (Danio rerio)
    Actinopterygii trim476
    tripartite motif containing 47
    27(a)
    possible ortholog
    10(26752552-26762609)


    ENSEMBL Gene Tree for TRIM7 (if available)
    TreeFam Gene Tree for TRIM7 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRIM7 gene
    TRIM42  TRIM262  TRIM392  TRIM342  TRIML12  TRIM272  TRIM582  TRIM682  
    TRIM102  TRIM152  TRIM602  TRIM222  TRIM172  TRIM52  TRIM62  TRIM6-TRIM342  
    TRIM212  TRIM382  TRIM39-RPP212  TRIM112  
    16 SIMAP similar genes for TRIM7 using alignment to 1 protein entry:     TRIM7_HUMAN:
    TRIM39R    TRIM15    TRIM10    TRIM27    TRIM39    ZNFB7
    TRIM11    TRIM58    TRIM21    TRIM41    MEFV    TRIM68
    TRIM75    TRIM38    TRIM6    TRIM60

    TRIM7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/310 NCBI SNPs in TRIM7 are shown (see all 310    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs27709351,2
    C,--175350627(+) GGAGGT/CGGAGA 1 -- us2k12Minor allele frequency- C:0.25NA WA 4
    rs591269141,2
    F,--175350716(+) AATAAC/GAATAA 1 -- us2k11Minor allele frequency- G:0.07WA 118
    rs27709361,2
    C,--175350796(+) TCACAC/TGAGGT 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs131801721,2
    C,--175351296(+) catccG/Atctcc 1 -- us2k12Minor allele frequency- A:0.04NA 122
    rs100612611,2
    C,H,--175351376(+) ggagaG/Aaggat 1 -- us2k1 trp36Minor allele frequency- A:0.02NS EA WA 502
    rs131631161,2
    H--175351437(+) gcaacA/Gaagcg 1 -- us2k14Minor allele frequency- G:0.00NS EA 418
    rs589347811,2
    C,--175351681(+) GGCATC/TGAGCA 2 -- us2k12Minor allele frequency- T:0.04WA 120
    rs27709371,2
    C,F,A,--175351721(+) CCACAG/CGACTG 2 -- us2k16Minor allele frequency- C:0.19NA WA CSA EA 364
    rs100546301,2
    C,F,A,--175351823(+) GGAACC/AGCAGG 2 -- us2k14Minor allele frequency- A:0.46NA WA CSA 124
    rs100615311,2
    C,F,A,--175351827(+) CAGCAA/GGGAGG 2 -- us2k14Minor allele frequency- G:0.46NA WA CSA 124

    HapMap Linkage Disequilibrium report for TRIM7 (180620924 - 180632293 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for TRIM7
         2 CNVs: 51656 53320

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIM7
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TRIM7 for disorders           About GeneDecksing

    OMIM gene information: 609315    OMIM disorders: --

    1 disease for TRIM7:    About MalaCards
    precocious puberty


    Export disorders for TRIM7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRIM7 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TRIM7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The tripartite motif family identifies cell compartments. (PubMed id 11331580)1, 2, 3 Reymond A.... Ballabio A. (2001)
    2. Structure-function analysis of GNIP, the glycogenin-interacting protein. (PubMed id 14984203)1, 2 Zhai L.... Roach P.J. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. GNIP, a novel protein that binds and activates glycogenin, the self- glucosylating initiator of glycogen biosynthesis. (PubMed id 11916970)1, 2 Skurat A.V.... Roach P.J. (2002)
    5. Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7. (PubMed id 21940674)1 Liang Q.... Zhu F. (2011)
    6. Functional interactions between ubiquitin E2 enzymes a nd TRIM proteins. (PubMed id 21143188)1 Napolitano L.M....Meroni G. (2011)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81786 HGNC: 16278 AceView: TRIM7 Ensembl:ENSG00000146054 euGenes: HUgn81786
    ECgene: TRIM7 H-InvDB: TRIM7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRIM7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRIM7 gene:
    Search GeneIP for patents involving TRIM7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     OriGene Antibodies for TRIM7   OriGene shRNA RFP for TRIM7  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIM7   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIM7  
     OriGene Protein Over-expression Lysate for TRIM7   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for TRIM7   OriGene 3'-UTR Clone for TRIM7  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM7   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM7  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TRIM7   OriGene Custom Protein Services for TRIM7  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRIM7
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIM7
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM7
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM7
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM7
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM7
     GenScript Custom Purified and Recombinant Proteins Services for TRIM7 GenScript cDNA clones with any tag delivered in your preferred vector for TRIM7
     GenScript Custom Assay Services for TRIM7 GenScript Custom Superior Antibodies Services for TRIM7
     GenScript Custom overexpressing Cell Line Services for TRIM7 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TRIM7 promoter
     Search Chromatin IP Primers for TRIM7
     RT2 qPCR Primer Assay in human, mouse, rat TRIM7
     Search GNC Networks for TRIM7
     SABiosciences Custom PCR Arrays for TRIM7
     Search Tocris compounds for TRIM7
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TRIM7 antibodies
     TRIM7 lysates
     Search for Antibodies for TRIM7 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for TRIM7
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     TRIM7 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for TRIM7
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM7
     SwitchGear 3'UTR luciferase reporter plasmids for TRIM7
     SwitchGear Promoter luciferase reporter plasmids for TRIM7
     ThermoFisher Antibodies for TRIM7
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM7
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TRIM7 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4