Aliases for TRIM69 Gene
External Ids for TRIM69 Gene
Previous HGNC Symbols for TRIM69 Gene
Previous GeneCards Identifiers for TRIM69 Gene
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for TRIM69 Gene
TRIM69 (Tripartite Motif Containing 69) is a Protein Coding gene. Diseases associated with TRIM69 include herpes simplex encephalitic 6. Among its related pathways are Immune System and Antigen processing- Ubiquitination and Proteasome degradation. GO annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is TRIM50.
UniProtKB/Swiss-Prot for TRIM69 Gene
May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis.