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Aliases for TRIM67 Gene

Aliases for TRIM67 Gene

  • Tripartite Motif Containing 67 2 3
  • TNL 3 4
  • Tripartite Motif-Containing Protein 67 3
  • Tripartite Motif-Containing 67 2
  • TRIM9-Like Protein TNL 3
  • TRIM9-Like Protein 4

External Ids for TRIM67 Gene

Previous GeneCards Identifiers for TRIM67 Gene

  • GC01P227606
  • GC01P229365
  • GC01P231298
  • GC01P201782

Summaries for TRIM67 Gene

GeneCards Summary for TRIM67 Gene

TRIM67 (Tripartite Motif Containing 67) is a Protein Coding gene. An important paralog of this gene is MID1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM67 Gene

Genomics for TRIM67 Gene

Regulatory Elements for TRIM67 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TRIM67 Gene

231,162,112 bp from pter
231,221,568 bp from pter
59,457 bases
Plus strand

Genomic View for TRIM67 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIM67 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM67 Gene

Proteins for TRIM67 Gene

  • Protein details for TRIM67 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tripartite motif-containing protein 67
    Protein Accession:
    Secondary Accessions:
    • Q5TER7
    • Q5TER8
    • Q7Z4K7

    Protein attributes for TRIM67 Gene

    783 amino acids
    Molecular mass:
    83823 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC86689.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

    Alternative splice isoforms for TRIM67 Gene


neXtProt entry for TRIM67 Gene

Proteomics data for TRIM67 Gene at MOPED

Post-translational modifications for TRIM67 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM67 Gene

No data available for DME Specific Peptides for TRIM67 Gene

Domains for TRIM67 Gene

Suggested Antigen Peptide Sequences for TRIM67 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 2 B box-type zinc fingers.
  • Contains 1 B30.2/SPRY domain.
  • Contains 1 COS domain.
  • Contains 1 fibronectin type-III domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 2 B box-type zinc fingers.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM67: view

Function for TRIM67 Gene

Gene Ontology (GO) - Molecular Function for TRIM67 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with TRIM67: view

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM67

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIM67 Gene

Localization for TRIM67 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRIM67 Gene

Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated. {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for TRIM67 Gene COMPARTMENTS Subcellular localization image for TRIM67 gene
Compartment Confidence
nucleus 3
cytoskeleton 2
cytosol 2

Gene Ontology (GO) - Cellular Components for TRIM67 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005737 cytoplasm IEA --
GO:0005856 cytoskeleton IEA --
genes like me logo Genes that share ontologies with TRIM67: view

Pathways for TRIM67 Gene

SuperPathways for TRIM67 Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays
    • Ubiquitin Ligases in human,mouse,rat

Interacting Proteins for TRIM67 Gene

Gene Ontology (GO) - Biological Process for TRIM67 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010976 positive regulation of neuron projection development IEA --
GO:0046580 negative regulation of Ras protein signal transduction IEA --
GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process IEA --
genes like me logo Genes that share ontologies with TRIM67: view

No data available for Pathways by source for TRIM67 Gene

Transcripts for TRIM67 Gene

mRNA/cDNA for TRIM67 Gene

Unigene Clusters for TRIM67 Gene

Tripartite motif containing 67:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM67

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM67 Gene

No ASD Table

Relevant External Links for TRIM67 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRIM67 Gene

mRNA expression in normal human tissues for TRIM67 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TRIM67 Gene

This gene is overexpressed in Brain - Cerebellum (15.3) and Brain - Cerebellar Hemisphere (14.7).

Protein differential expression in normal tissues for TRIM67 Gene

This gene is overexpressed in Fetal Brain (62.0) and Retina (6.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TRIM67 Gene

SOURCE GeneReport for Unigene cluster for TRIM67 Gene Hs.655089

genes like me logo Genes that share expressions with TRIM67: view

Expression partners for TRIM67 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TRIM67 Gene

Orthologs for TRIM67 Gene

This gene was present in the common ancestor of animals.

Orthologs for TRIM67 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TRIM67 35
  • 90.49 (n)
  • 95.14 (a)
TRIM67 36
  • 82 (a)
(Canis familiaris)
Mammalia TRIM67 35
  • 90.21 (n)
  • 95.77 (a)
TRIM67 36
  • 96 (a)
(Mus musculus)
Mammalia Trim67 35
  • 86.41 (n)
  • 92.71 (a)
Trim67 16
Trim67 36
  • 94 (a)
(Pan troglodytes)
Mammalia TRIM67 35
  • 99.19 (n)
  • 99.49 (a)
TRIM67 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Trim67 35
  • 86.54 (n)
  • 92.34 (a)
(Monodelphis domestica)
Mammalia TRIM67 36
  • 90 (a)
(Ornithorhynchus anatinus)
Mammalia TRIM67 36
  • 89 (a)
(Gallus gallus)
Aves TRIM67 35
  • 79.22 (n)
  • 88.98 (a)
TRIM67 36
  • 90 (a)
(Anolis carolinensis)
Reptilia TRIM67 36
  • 83 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia trim67 35
  • 72 (n)
  • 81.74 (a)
(Danio rerio)
Actinopterygii LOC100332164 35
  • 73.61 (n)
  • 76.81 (a)
TRIM67 36
  • 75 (a)
fruit fly
(Drosophila melanogaster)
Insecta Trim9 36
  • 43 (a)
(Caenorhabditis elegans)
Secernentea trim-9 36
  • 37 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
Species with no ortholog for TRIM67:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TRIM67 Gene

Gene Tree for TRIM67 (if available)
Gene Tree for TRIM67 (if available)

Paralogs for TRIM67 Gene

(5) SIMAP similar genes for TRIM67 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with TRIM67: view

Variants for TRIM67 Gene

Sequence variations from dbSNP and Humsavar for TRIM67 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs61394534 -- 231,206,223(+) AAGAG(A/T)TCGAG intron-variant
rs61444675 -- 231,170,762(+) TAATG(A/G)TTGCT intron-variant
rs61708532 -- 231,172,647(+) TGGGC(C/T)TTAGT intron-variant
rs111266010 -- 231,205,697(+) CTCCA(C/G)CCTGG intron-variant
rs80329296 -- 231,205,725(+) TGTCT(A/C)AAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRIM67 Gene

Variant ID Type Subtype PubMed ID
esv2494270 CNV Deletion 19546169
esv1972788 CNV Deletion 18987734
esv2724839 CNV Deletion 23290073
esv2678520 CNV Deletion 23128226
esv7591 CNV Loss 19470904
nsv517116 CNV Loss 19592680
esv2669296 CNV Deletion 23128226
esv27426 CNV Loss 19812545
nsv818833 CNV Loss 17921354
dgv18n17 CNV Loss 16327808
esv2555185 CNV Insertion 19546169
nsv873292 CNV Gain 21882294
esv2182022 CNV Deletion 18987734
esv2724850 CNV Deletion 23290073

Relevant External Links for TRIM67 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM67 Gene

Disorders for TRIM67 Gene

Relevant External Links for TRIM67

Genetic Association Database (GAD)

No disorders were found for TRIM67 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for TRIM67 Gene

Publications for TRIM67 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding. (PMID: 16434393) Short K.M. … Cox T.C. (J. Biol. Chem. 2006) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3

Products for TRIM67 Gene

Sources for TRIM67 Gene

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