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TRIM66 Gene

protein-coding   GIFtS: 46
GCID: GC11M008595

Tripartite Motif Containing 66

(Previous names: chromosome 11 open reading frame 29, tripartite motif-containing...)
(Previous symbol: C11orf29)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tripartite Motif Containing 661 2     Chromosome 11 Open Reading Frame 291
C11orf291 2 3     TIF1DELTA2
Tripartite Motif-Containing 661 2     Transcriptional Intermediary Factor 1 Delta2
TIF1D2 5     Tripartite Motif-Containing Protein 662
KIAA02983 5     

External Ids:    HGNC: 290051   Entrez Gene: 98662   Ensembl: ENSG000001664367   OMIM: 6120005   UniProtKB: O150163   

Export aliases for TRIM66 gene to outside databases

Previous GC identifer: GC11M008301


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TRIM66 Gene:
TRIM66 (tripartite motif containing 66) is a protein-coding gene. An important paralog of this gene is TRIM33.

UniProtKB/Swiss-Prot: TRI66_HUMAN, O15016
Function: May function as transcription repressor; The repressive effects are mediated, at least in part, by
recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through
CBX3 complex formation and centromere association (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRIM66 gene promoter:
         STAT5A   AP-4   LUN-1   GATA-1   FOXL1   MZF-1   E2F-1   E2F   Msx-1   Hlf   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TRIM66

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM66


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.4

TRIM66 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM66 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M008595:  view genomic region     (about GC identifiers)

Start:
8,633,584 bp from pter      End:
8,693,413 bp from pter
Size:
59,830 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TRI66_HUMAN, O15016 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 66  
Size: 1216 amino acids; 134663 Da
Subunit: Can form homodimers and heterodimers. Interacts with CBX5, CBX1 and CBX3 via PxVxL motif (By similarity)
Sequence caution: Sequence=BAA20758.2; Type=Frameshift; Positions=797;
Secondary accessions: Q9BQQ4
Alternative splicing: 2 isoforms:  O15016-1   O15016-2   

Explore the universe of human proteins at neXtProt for TRIM66: NX_O15016

Explore proteomics data for TRIM66 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRIM66 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055633.1  
    ENSEMBL proteins: 
     ENSP00000384876   ENSP00000437234   ENSP00000299550  

    TRIM66 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for TRIM66
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRIM66

     
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    Search antibodies-online for proteins for TRIM66 

     
    antibodies-online peptides for TRIM66

    TRIM66 Antibody Products:

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    Novus Biologicals TRIM66 Antibody
    Abcam antibodies for TRIM66
    Cloud-Clone Corp. Antibodies for TRIM66
    Search ThermoFisher Antibodies for TRIM66
    antibodies-online antibodies for TRIM66 (2 products) 

    TRIM66 Assay Products:

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    Cloud-Clone Corp. ELISAs for TRIM66
    Cloud-Clone Corp. CLIAs for TRIM66
    Search eBioscience for ELISAs for TRIM66 
    antibodies-online kits for TRIM66 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRIM: Tripartite motif containing / Tripartite motif containing
    PHF: Zinc fingers, PHD-type

    Selected InterPro protein domains (see all 8):
     IPR003649 Bbox_C
     IPR019786 Zinc_finger_PHD-type_CS
     IPR001965 Znf_PHD
     IPR001487 Bromodomain
     IPR000315 Znf_B-box

    Graphical View of Domain Structure for InterPro Entry O15016

    ProtoNet protein and cluster: O15016

    4 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001487 Bromodomain signature
    IPB001965 Zn-finger-like
    IPB003649 B-box


    UniProtKB/Swiss-Prot: TRI66_HUMAN, O15016
    Similarity: Contains 2 B box-type zinc fingers
    Similarity: Contains 1 bromo domain
    Similarity: Contains 1 PHD-type zinc finger


    Find genes that share domains with TRIM66           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRI66_HUMAN, O15016
    Function: May function as transcription repressor; The repressive effects are mediated, at least in part, by
    recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through
    CBX3 complex formation and centromere association (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0042803protein homodimerization activity ----
         
    Find genes that share ontologies with TRIM66           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Trim66):
     cellular 

    Find genes that share phenotypes with TRIM66           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TRIM66

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TRIM66 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TRIM66 (see all 85):
    hsa-miR-124* hsa-miR-582-3p hsa-miR-520e hsa-miR-106a hsa-miR-15a hsa-miR-93 hsa-miR-556-3p hsa-miR-4273
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    GenScript: all cDNA clones in your preferred vector: TRIM66 (NM_014818)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM66
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRIM66

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TRI66_HUMAN, O15016: Nucleus. Note=Forms discrete foci within the centromeric chromocenter and surrounding
    nucleoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0010369chromocenter ----
    GO:0016235aggresome IDA--

    Find genes that share ontologies with TRIM66           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRIM66
    Interactions:

        Search GeneGlobe Interaction Network for TRIM66

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for TRIM66 (O150163 ENSP000002995504) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CBX5P459733, ENSP000002098754I2D: score=1 STRING: ENSP00000209875
    CBX1P839163, ENSP000002256034I2D: score=1 STRING: ENSP00000225603
    CBX3ENSP000003366874STRING: ENSP00000336687
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045892negative regulation of transcription, DNA-templated ----

    Find genes that share ontologies with TRIM66           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRIM66 (TRI66)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRIM66 gene: 
    NM_014818.1  

    Unigene Cluster for TRIM66:

    Tripartite motif containing 66
    Hs.130836  [show with all ESTs]
    Unigene Representative Sequence: NM_014818
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000402157 ENST00000481014 ENST00000529211 ENST00000525788 ENST00000530502
    ENST00000531498(uc009yfq.3) ENST00000529057 ENST00000299550(uc010rbo.2)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TRIM66 (see all 85):
    hsa-miR-124* hsa-miR-582-3p hsa-miR-520e hsa-miR-106a hsa-miR-15a hsa-miR-93 hsa-miR-556-3p hsa-miR-4273
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRIM66
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    GenScript: all cDNA clones in your preferred vector: TRIM66 (NM_014818)
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRIM66
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM66
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM66
      QuantiTect SYBR Green Assays in human, mouse, rat TRIM66
      QuantiFast Probe-based Assays in human, mouse, rat TRIM66

    Additional mRNA sequence: 

    AK000908.1 AK307240.1 AK308310.1 BC031354.1 

    8 DOTS entries:

    DT.443203  DT.206912  DT.75100692  DT.120725985  DT.120683384  DT.40292791  DT.95124270  DT.120683380 

    Selected AceView cDNA sequences (see all 82):

    AB002296 AI537517 AK000908 BF436622 BG682280 AI347789 BC031354 AA465716 
    AU133532 BX116665 AI831043 CD107202 AA632341 AA286734 AA759118 AU117317 
    Z40307 AA861302 AI813370 AI052339 AI243330 CF143165 AW953503 AI675755 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRIM66 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGGAGGATA
    TRIM66 Expression
    About this image

    TRIM66 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRIM66 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.130836
        Custom PCR Arrays for TRIM66
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM66

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TRIM66 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim661 , 5 tripartite motif-containing 661, 5 86.44(n)1
    86.91(a)1
      7 (57.21 cM)5
    3306271  NM_001170912.11  NP_001164383.11 
     1094490065 
    chicken
    (Gallus gallus)
    Aves TRIM661 tripartite motif containing 66 63.07(n)
    57.36(a)
      423056  XM_004941392.1  XP_004941449.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRIM666
    tripartite motif containing 66
    52(a)
    1 ↔ 1
    2(112577231-112645520)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.241022 Xenopus laevis transcribed sequence with weak similarity to protein spO15164 (H.sapiens) TF1A_HUMAN Transcription intermediary factor 1-alpha (TIF1-alpha) less 73.65(n)    CB560073.1 
    zebrafish
    (Danio rerio)
    Actinopterygii trim666
    tripartite motif containing 66
    30(a)
    1 ↔ 1
    7(29760280-29799335) ENSDARG00000054332
    fruit fly
    (Drosophila melanogaster)
    Insecta mei-P266
    mei-P26
    12(a)
    1 → many
    X(9057288-9083342)
    worm
    (Caenorhabditis elegans)
    Secernentea nhl-26
    Protein NHL-2 (nhl-2) mRNA, complete cds
    11(a)
    1 → many
    III(4894647-4899085) WBGene00003598


    ENSEMBL Gene Tree for TRIM66 (if available)
    TreeFam Gene Tree for TRIM66 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRIM66 gene
    TRIM332  TRIM242  AIRE2  TRIM282  
    2 SIMAP similar genes for TRIM66 using alignment to 3 protein entries:     TRI66_HUMAN (see all proteins):
    AIRE    SP110

    Find genes that share paralogs with TRIM66           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRIM66 (see all 946)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1504982951,2
    --8633137(+) TGGTGA/GCTCAC 1 -- ds50010--------
    rs1854402411,2
    C--8633318(+) AGGATC/TGCTTG 1 -- ds50010--------
    rs1907041871,2
    --8633336(+) AAGGCA/GGAGGT 1 -- ds50010--------
    rs122860111,2
    C,F--8633339(+) GCGGAG/AGTTGC 1 -- ds50014Minor allele frequency- A:0.38NA CSA 8
    rs750648251,2
    C--8633425(+) AATAAG/TAAGAA 1 -- ds50010--------
    rs770075231,2
    C--8633428(+) AATAAG/TAAGAA 1 -- ds50013Minor allele frequency- T:0.05NA EA 242
    rs1453943321,2
    --8633577(+) TCCAGA/GACGCA 1 -- ds50010--------
    rs1158110451,2
    C,F--8633592(+) TTGGTA/GAAGAA 1 -- ut311Minor allele frequency- G:0.04WA 118
    rs778139671,2
    C--8633628(+) AATGTA/GTAGGT 1 -- ut310--------
    rs1448132661,2
    --8633802(+) CAGCTA/GATAAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TRIM66 (8633584 - 8693413 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TRIM66:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2751035CNV Loss17911159
    nsv896983CNV Loss21882294
    nsv499766OTHER Inversion21111241
    nsv7215OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM66
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM66

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612000    OMIM disorders: --


    Find genes that share disorders with TRIM66           About GenesLikeMe

    Genetic Association Database (GAD): TRIM66
    Human Genome Epidemiology (HuGE) Navigator: TRIM66 (2 documents)

    Export disorders for TRIM66 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRIM66 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with TRIM66)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1997)
    2. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (PubMed id 21102462)1, 4 Elks C.E....Murray A. (Nat. Genet. 2010)
    3. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PubMed id 11528127)1, 2 Amid C.... Schmidt E.R. (Cytogenet. Cell Genet. 2001)
    4. TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids. (PubMed id 15322135)1, 9 Khetchoumian K....Losson R. (J. Biol. Chem. 2004)
    5. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. (PubMed id 23563607)1 Berndt S.I....Ingelsson E. (Nat. Genet. 2013)
    6. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PubMed id 18854154)1 KAPnig R....Chanda S.K. (Cell 2008)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PubMed id 16751776)1 Girard A....Carmell M.A. (Nature 2006)
    9. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (Nature 2006)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9866 HGNC: 29005 AceView: KIAA0298 Ensembl:ENSG00000166436 euGenes: HUgn9866
    ECgene: TRIM66 H-InvDB: TRIM66

    (According to HUGE)
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    HUGE: KIAA0298

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TRIM66 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRIM66 gene:
    Search GeneIP for patents involving TRIM66

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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