Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TRIM66 Gene

protein-coding GIFtS: 46
GCID: GC11M008595

tripartite motif containing 66

(Previous names: chromosome 11 open reading frame 29, tripartite motif-containing...)
(Previous symbol: C11orf29)

Search for TRIM66
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Tripartite Motif Containing 66¹ ²		Chromosome 11 Open Reading Frame 29¹
C11orf29¹ ² ³		TIF1DELTA²
TIF1D¹ ² ⁵		Transcriptional Intermediary Factor 1 Delta²
KIAA0298¹ ³ ⁵		Tripartite Motif-Containing Protein 66²
Tripartite Motif-Containing 66¹ ²

External Ids:	HGNC: 29005¹	Entrez Gene: 9866²	Ensembl: ENSG00000166436⁷	OMIM: 612000⁵	UniProtKB: O15016³

Export aliases for TRIM66 gene to outside databases

Previous GC identifer: GC11M008301

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TRI66_HUMAN, O15016

Function: May function as transcription repressor; The repressive effects are mediated, at least in part, by

recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3

complex formation and centromere association (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TRIM66 gene promoter:
STAT5A AP-4 LUN-1 GATA-1 FOXL1 MZF-1 E2F-1 E2F Msx-1 Hlf
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for TRIM66

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM66

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4 Ensembl cytogenetic band: 11p15.4 HGNC cytogenetic band: 11p15.4

TRIM66 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM66 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M008595: view genomic region (about GC identifiers)

Start:	8,633,584 bp from pter	End:	8,693,413 bp from pter
Size:	59,830 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TRI66_HUMAN, O15016 (See protein sequence)

Recommended Name: Tripartite motif-containing protein 66

Size: 1216 amino acids; 134663 Da

Subunit: Can form homodimers and heterodimers. Interacts with CBX5, CBX1 and CBX3 via PxVxL motif (By similarity)

Subcellular location: Nucleus. Note=Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm

(By similarity)

Sequence caution: Sequence=BAA20758.2; Type=Frameshift; Positions=797;

Secondary accessions: Q9BQQ4

Alternative splicing: 2 isoforms: O15016-1 O15016-2

Explore the universe of human proteins at neXtProt for TRIM66: NX_O15016

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O15016

TRIM66 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055633.1

ENSEMBL proteins:

ENSP00000384876 ENSP00000437234 ENSP00000299550

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: TRIM66 OriGene Custom Protein Services for TRIM66
	GenScript Custom Purified and Recombinant Proteins Services for TRIM66
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for TRIM66

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0010369	chromocenter	--	--
GO:0016235	aggresome	IDA	--

TRIM66 for ontologies About GeneDecksing

TRIM66 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for TRIM66
	GenScript Custom Superior Antibodies Services for TRIM66
	Novus Biologicals TRIM66 Antibody
	Search for Antibodies for TRIM66 at Abcam
	Uscn Antibodies for TRIM66
	Search ThermoFisher Antibodies for TRIM66

Assay Products for TRIM66:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for TRIM66
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for TRIM66

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TRIM66 for domains About GeneDecksing

5/8 InterPro domains/families (see all 8):

IPR003649 Bbox_C

IPR019786 Zinc_finger_PHD-type_CS

IPR001965 Znf_PHD

IPR001487 Bromodomain

IPR000315 Znf_B-box

Graphical View of Domain Structure for InterPro Entry O15016

ProtoNet protein and cluster: O15016

4 Blocks protein families:

IPB000315 B-box zinc finger signature

IPB001487 Bromodomain signature

IPB001965 Zn-finger-like

IPB003649 B-box

UniProtKB/Swiss-Prot: TRI66_HUMAN, O15016

Similarity: Contains 2 B box-type zinc fingers

Similarity: Contains 1 bromo domain

Similarity: Contains 1 PHD-type zinc finger

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: TRI66_HUMAN, O15016

Function: May function as transcription repressor; The repressive effects are mediated, at least in part, by

recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3

complex formation and centromere association (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: TRIM66 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM66
		8/85 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM66 (see all 85):
		hsa-miR-124* hsa-miR-582-3p hsa-miR-520e hsa-miR-106a hsa-miR-15a hsa-miR-93 hsa-miR-556-3p hsa-miR-4273

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIM66 (see all 4) OriGene shRNA RFP: TRIM66 OriGene siRNA: TRIM66
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM66

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for TRIM66

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM66 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM66 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TRIM66 (NM_014818)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM66
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRIM66

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TRIM66
		Search LifeMap BioReagents cell lines for TRIM66

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM66

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--
GO:0008270	zinc ion binding	IEA	--
GO:0042803	protein homodimerization activity	--	--

TRIM66 for ontologies About GeneDecksing

Animal Models:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Trim66):

cellular

TRIM66 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TRIM66

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for TRIM66 (O15016³ ENSP00000299550⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CBX5	P45973³, ENSP00000209875⁴	I2D: score=1 STRING: ENSP00000209875
CBX1	P83916³, ENSP00000225603⁴	I2D: score=1 STRING: ENSP00000225603
CBX3	ENSP00000336687⁴	STRING: ENSP00000336687

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0045892	negative regulation of transcription, DNA-dependent	--	--

TRIM66 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TRIM66
Search CenterWatch for drugs/clinical trials and news about TRIM66 / TRI66

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TRIM66 gene:

NM_014818.1

Unigene Cluster for TRIM66:

Tripartite motif containing 66

Hs.130836 [show with all ESTs]

Unigene Representative Sequence: NM_014818

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000402157 ENST00000481014 ENST00000529211 ENST00000525788 ENST00000530502

ENST00000531498(uc009yfq.3) ENST00000529057 ENST00000299550(uc010rbo.2)

miRNA Products:		OriGene 3'-UTR Clone: TRIM66 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM66
		8/85 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM66 (see all 85):
		hsa-miR-124* hsa-miR-582-3p hsa-miR-520e hsa-miR-106a hsa-miR-15a hsa-miR-93 hsa-miR-556-3p hsa-miR-4273

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIM66 (see all 4) OriGene shRNA RFP: TRIM66 OriGene siRNA: TRIM66
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM66

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM66 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM66 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TRIM66 (NM_014818)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM66
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRIM66

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIM66 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat TRIM66
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM66
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM66

Additional cDNA sequence:

AK000908.1 AK307240.1 AK308310.1 BC031354.1

8 DOTS entries:

DT.443203 DT.206912 DT.75100692 DT.120725985 DT.120683384 DT.40292791 DT.95124270 DT.120683380

24/82 AceView cDNA sequences (see all 82):

BC031354 BX116665 BF436622 AI347789 AA632341 AA759118 AB002296 CD107202

AU133532 AI537517 AK000908 AA465716 AI831043 AU117317 BG682280 AA286734

AI286048 BG570211 BG654805 BU152921 AL079535 BQ448518 BQ372964 AW663213

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TRIM66 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGGAGGATA

About this image
See TRIM66 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TRIM66

SOURCE GeneReport for Unigene cluster: Hs.130836

SABiosciences Custom PCR Arrays for TRIM66

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIM66 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat TRIM66
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM66
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM66

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM66

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TRIM66 gene from 5/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	TRIM66¹	tripartite motif containing 66	61.21(n) 55.53(a)		423056 XM_420989.3 XP_420989.3
lizard (Anolis carolinensis)	Reptilia	TRIM66⁶	--	49(a)	1 ↔ 1	2(112578554-112645466)
African clawed frog (Xenopus laevis)	Amphibia	Xl.24102²	Xenopus laevis transcribed sequence with weak similarity to protein spO15164 (H.sapiens) TF1A_HUMAN Transcription intermediary factor 1-alpha (TIF1-alpha) less	73.65(n)		CB560073.1
zebrafish (Danio rerio)	Actinopterygii	trim66⁶ trim66⁶ (see all 3)	tripartite motif containing 66 (see all 3)	51(a) 28(a) (see all 3)	1 ↔ many 1 ↔ many (see all 3)	7(29781339-29799390) 7(29761279-29788043)
fruit fly (Drosophila melanogaster)	Insecta	bon⁶	bonus	15(a)	1 → many	3R(16418881-16438262)

ENSEMBL Gene Tree for TRIM66 (if available)
TreeFam Gene Tree for TRIM66 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TRIM66 gene

TRIM33² TRIM24² TRIM28²

3 SIMAP similar genes for TRIM66 using alignment to 3 protein entries: TRI66_HUMAN (see all proteins):

AIRE SP110 FLJ00340

TRIM66 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs150498295^1,2		--	8633137(+)	`TGGTGA/GCTCAC`	1	--	ds500¹		0	--	--	--	--
rs185440241^1,2		--	8633318(+)	`AGGATC/TGCTTG`	1	--	ds500¹		0	--	--	--	--
rs190704187^1,2		--	8633336(+)	`AAGGCA/GGAGGT`	1	--	ds500¹		0	--	--	--	--
rs12286011^1,2	C,F,	--	8633339(+)	`GCGGAG/AGTTGC`	1	--	ds500¹		4		NA CSA	8
rs75064825^1,2		--	8633425(+)	`AATAAG/TAAGAA`	1	--	ds500¹		0	--	--	--	--
rs77007523^1,2	C,	--	8633428(+)	`AATAAG/TAAGAA`	1	--	ds500¹		3		NA EA	242
rs145394332^1,2		--	8633577(+)	`TCCAGA/GACGCA`	1	--	ds500¹		0	--	--	--	--
rs115811045^1,2	F,	--	8633592(+)	`TTGGTA/GAAGAA`	1	--	ut3¹		1		WA	118
rs77813967^1,2		--	8633628(+)	`AATGTA/GTAGGT`	1	--	ut3¹		0	--	--	--	--
rs144813266^1,2		--	8633802(+)	`CAGCTA/GATAAG`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TRIM66 (8633584 - 8693413 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TRIM66
1 CNV: 9175

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIM66

DNA2.0 Custom Variant and Variant Library Synthesis for TRIM66

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TRIM66 for disorders About MalaCards

TRIM66 for disorders About GeneDecksing

OMIM gene information: 612000 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: TRIM66 (2 documents)

Export disorders for TRIM66 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TRIM66 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TRIM66)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)^{1, 2, 3} Nagase T.... Ohara O. (1997)
Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PubMed id 11528127)^{1, 2} Amid C.... Schmidt E.R. (2001)
TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids. (PubMed id 15322135)^{1, 9} Khetchoumian K....Losson R. (2004)
Thirty new loci for age at menarche identified by a m eta-analysis of genome-wide association studies. (PubMed id 21102462)¹ Elks C.E....Murray A. (2010)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
A germline-specific class of small RNAs binds mammali an Piwi proteins. (PubMed id 16751776)¹ Girard A....Carmell M.A. (2006)
Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)² Taylor T.D....Sakaki Y. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 9866	HGNC: 29005	AceView: KIAA0298	Ensembl:ENSG00000166436	euGenes: HUgn9866
ECgene: TRIM66	H-InvDB: TRIM66

(According to HUGE)
About This Section

HUGE: KIAA0298

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TRIM66	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TRIM66 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for TRIM66 gene:
Search GeneIP for patents involving TRIM66

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for TRIM66
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIM66		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIM66
	OriGene Protein Over-expression Lysate for TRIM66		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for TRIM66		OriGene 3'-UTR Clone for TRIM66
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM66		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM66
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for TRIM66		OriGene Custom Protein Services for TRIM66
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRIM66
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIM66
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM66
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM66
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM66
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM66

	GenScript Custom Purified and Recombinant Proteins Services for TRIM66		GenScript cDNA clones with any tag delivered in your preferred vector for TRIM66
	GenScript Custom Assay Services for TRIM66		GenScript Custom Superior Antibodies Services for TRIM66
	GenScript Custom overexpressing Cell Line Services for TRIM66		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in TRIM66 promoter
	Search Chromatin IP Primers for TRIM66
	RT² qPCR Primer Assay in human, mouse, rat TRIM66
	Search GNC Networks for TRIM66
	SABiosciences Custom PCR Arrays for TRIM66

Search Tocris compounds for TRIM66

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	TRIM66 antibodies

	Search for Antibodies for TRIM66 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for TRIM66
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

TRIM66 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for TRIM66

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM66

	Browse SwitchGear 3'UTR luciferase reporter plasmids for TRIM66
	Browse SwitchGear Promoter luciferase reporter plasmids for TRIM66

Search ThermoFisher Antibodies for TRIM66

Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRIM66

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes TRIM66 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

TRIM66 Gene

tripartite motif containing 66

Aliases
for TRIM66 gene

Summaries
for TRIM66 gene

Genomic Views
for TRIM66 gene

Proteins
for TRIM66 gene

Protein Domains /
Families
for TRIM66 gene

Function
for TRIM66 gene

Pathways & Interactions
for TRIM66 gene

Drugs & Compounds
for TRIM66 gene

Transcripts
for TRIM66 gene

Expression
for TRIM66 gene

Orthologs
for TRIM66 gene

Paralogs
for TRIM66 gene

Genomic Variants
for TRIM66 gene

Disorders / Diseases
for TRIM66 gene

Publications
for TRIM66 gene

External Searches for TRIM66 gene

Genome Databases showing TRIM66 gene

Other Databases showing TRIM66 gene

Specialized Databases showing TRIM66 gene

Intellectual Property
for TRIM66 gene

Products
for TRIM66 gene

View Random Gene

Advanced Search

Export list of displayed genes

TRIM66 Gene

tripartite motif containing 66

Aliasesfor TRIM66 gene

Summariesfor TRIM66 gene

Genomic Viewsfor TRIM66 gene

Proteinsfor TRIM66 gene

Protein Domains /Familiesfor TRIM66 gene

Functionfor TRIM66 gene

Pathways & Interactionsfor TRIM66 gene

Drugs & Compoundsfor TRIM66 gene

Transcriptsfor TRIM66 gene

Expression for TRIM66 gene

Orthologsfor TRIM66 gene

Paralogsfor TRIM66 gene

Genomic Variantsfor TRIM66 gene

Disorders / Diseasesfor TRIM66 gene

Publicationsfor TRIM66 gene

External Searches for TRIM66 gene

Genome Databases showing TRIM66 gene

Other Databases showing TRIM66 gene

Specialized Databases showing TRIM66 gene

Intellectual Propertyfor TRIM66 gene

Productsfor TRIM66 gene

View Random Gene

Aliases
for TRIM66 gene

Summaries
for TRIM66 gene

Genomic Views
for TRIM66 gene

Proteins
for TRIM66 gene

Protein Domains /
Families
for TRIM66 gene

Function
for TRIM66 gene

Pathways & Interactions
for TRIM66 gene

Drugs & Compounds
for TRIM66 gene

Transcripts
for TRIM66 gene

Expression
for TRIM66 gene

Orthologs
for TRIM66 gene

Paralogs
for TRIM66 gene

Genomic Variants
for TRIM66 gene

Disorders / Diseases
for TRIM66 gene

Publications
for TRIM66 gene

Intellectual Property
for TRIM66 gene

Products
for TRIM66 gene