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Aliases for TRIM64C Gene

Aliases for TRIM64C Gene

  • Tripartite Motif Containing 64C 2 3 5
  • Tripartite Motif-Containing 64C 2

External Ids for TRIM64C Gene

Previous GeneCards Identifiers for TRIM64C Gene

  • GC11M049038
  • GC11M048793
  • GC11M049075
  • GC11M049592
  • GC11M049618
  • GC11M050824

Summaries for TRIM64C Gene

GeneCards Summary for TRIM64C Gene

TRIM64C (Tripartite Motif Containing 64C) is a Protein Coding gene. An important paralog of this gene is TRIM64B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM64C Gene

Genomics for TRIM64C Gene

Genomic Location for TRIM64C Gene

Chromosome:
11
Start:
49,053,714 bp from pter
End:
49,059,112 bp from pter
Size:
5,399 bases
Orientation:
Minus strand

Genomic View for TRIM64C Gene

Genes around TRIM64C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM64C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM64C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM64C Gene

No data available for Regulatory Elements for TRIM64C Gene

Proteins for TRIM64C Gene

  • Protein details for TRIM64C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NLI5-TR64C_HUMAN
    Recommended name:
    Putative tripartite motif-containing protein 64C
    Protein Accession:
    A6NLI5

    Protein attributes for TRIM64C Gene

    Size:
    447 amino acids
    Molecular mass:
    51329 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM64C Gene

Post-translational modifications for TRIM64C Gene

No Post-translational modifications

Other Protein References for TRIM64C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM64C Gene

Domains & Families for TRIM64C Gene

Gene Families for TRIM64C Gene

Protein Domains for TRIM64C Gene

Suggested Antigen Peptide Sequences for TRIM64C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NLI5

UniProtKB/Swiss-Prot:

TR64C_HUMAN :
  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 1 B box-type zinc finger.
Domain:
  • Contains 1 B30.2/SPRY domain.
Family:
  • Belongs to the TRIM/RBCC family.
Similarity:
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM64C: view

Function for TRIM64C Gene

Gene Ontology (GO) - Molecular Function for TRIM64C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with TRIM64C: view

Phenotypes for TRIM64C Gene

GenomeRNAi human phenotypes for TRIM64C:
genes like me logo Genes that share phenotypes with TRIM64C: view

Animal Model Products

CRISPR Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIM64C Gene

Localization for TRIM64C Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRIM64C Gene COMPARTMENTS Subcellular localization image for TRIM64C gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for TRIM64C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM64C: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRIM64C Gene

Pathways & Interactions for TRIM64C Gene

SuperPathways for TRIM64C Gene

No Data Available

Interacting Proteins for TRIM64C Gene

Gene Ontology (GO) - Biological Process for TRIM64C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRIM64C Gene

Drugs & Compounds for TRIM64C Gene

No Compound Related Data Available

Transcripts for TRIM64C Gene

mRNA/cDNA for TRIM64C Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM64C Gene

No ASD Table

Relevant External Links for TRIM64C Gene

GeneLoc Exon Structure for
TRIM64C
ECgene alternative splicing isoforms for
TRIM64C

Expression for TRIM64C Gene

mRNA expression in normal human tissues for TRIM64C Gene

Protein differential expression in normal tissues from HIPED for TRIM64C Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TRIM64C Gene



Protein tissue co-expression partners for TRIM64C Gene

NURSA nuclear receptor signaling pathways regulating expression of TRIM64C Gene:

TRIM64C

SOURCE GeneReport for Unigene cluster for TRIM64C Gene:

Hs.740240
genes like me logo Genes that share expression patterns with TRIM64C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TRIM64C Gene

Orthologs for TRIM64C Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM64C Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TRIM64 34
  • 73.17 (n)
  • 60.99 (a)
-- 35
  • 59 (a)
ManyToMany
-- 35
  • 50 (a)
ManyToMany
-- 35
  • 57 (a)
ManyToMany
-- 35
  • 57 (a)
ManyToMany
-- 35
  • 56 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia TRIM64 34
  • 74.65 (n)
  • 61.66 (a)
-- 35
  • 56 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia TRIM64C 34
  • 99.11 (n)
  • 98.21 (a)
TRIM 35
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 33 (a)
ManyToMany
-- 35
  • 26 (a)
ManyToMany
-- 35
  • 26 (a)
ManyToMany
-- 35
  • 31 (a)
ManyToMany
-- 35
  • 19 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 25 (a)
ManyToMany
-- 35
  • 31 (a)
ManyToMany
-- 35
  • 30 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 18 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 25 (a)
ManyToMany
-- 35
  • 30 (a)
ManyToMany
-- 35
  • 17 (a)
ManyToMany
-- 35
  • 20 (a)
ManyToMany
-- 35
  • 22 (a)
ManyToMany
-- 35
  • 22 (a)
ManyToMany
-- 35
  • 27 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii trim109 35
  • 18 (a)
ManyToMany
Species where no ortholog for TRIM64C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM64C Gene

ENSEMBL:
Gene Tree for TRIM64C (if available)
TreeFam:
Gene Tree for TRIM64C (if available)

Paralogs for TRIM64C Gene

Pseudogenes.org Pseudogenes for TRIM64C Gene

genes like me logo Genes that share paralogs with TRIM64C: view

Variants for TRIM64C Gene

Sequence variations from dbSNP and Humsavar for TRIM64C Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs7947781 -- 49,058,984(+) TCTTC(G/T)GAGCA reference, synonymous-codon
rs7949585 -- 49,056,194(+) TTTAA(G/T)ATGGA intron-variant
rs1819409 -- 49,057,798(-) TTCAC(C/T)AAGAC intron-variant
rs1918842 -- 49,053,370(-) CCTGT(A/G)CACTT downstream-variant-500B
rs34132343 -- 49,054,314(+) AAAGG(-/G)AAACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRIM64C Gene

Variant ID Type Subtype PubMed ID
esv2421548 CNV deletion 20811451
esv2666171 CNV deletion 23128226
esv2671725 CNV deletion 23128226
esv2744485 CNV deletion 23290073
esv2759824 CNV gain+loss 17122850
esv2760191 CNV loss 21179565
esv3626291 CNV loss 21293372
esv3891984 CNV gain 25118596
esv3891986 CNV gain 25118596
esv3891994 CNV loss 25118596
nsv1051896 CNV loss 25217958
nsv1054955 CNV loss 25217958
nsv1159864 CNV deletion 26073780
nsv467874 CNV gain 19166990
nsv469956 CNV gain 18288195
nsv554223 CNV gain 21841781
nsv554346 CNV loss 21841781
nsv832145 CNV gain 17160897
nsv975174 CNV duplication 23825009

Variation tolerance for TRIM64C Gene

Gene Damage Index Score: 9.60; 89.03% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRIM64C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRIM64C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM64C Gene

Disorders for TRIM64C Gene

Relevant External Links for TRIM64C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRIM64C

No disorders were found for TRIM64C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM64C Gene

Publications for TRIM64C Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 65

Products for TRIM64C Gene

Sources for TRIM64C Gene

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