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Aliases for TRIM64B Gene

Aliases for TRIM64B Gene

  • Tripartite Motif Containing 64B 2 3 5
  • Tripartite Motif-Containing 64B 2

External Ids for TRIM64B Gene

Previous GeneCards Identifiers for TRIM64B Gene

  • GC11M089248
  • GC11M089603

Summaries for TRIM64B Gene

GeneCards Summary for TRIM64B Gene

TRIM64B (Tripartite Motif Containing 64B) is a Protein Coding gene. An important paralog of this gene is TRIM64.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM64B Gene

Genomics for TRIM64B Gene

Genomic Location for TRIM64B Gene

Chromosome:
11
Start:
89,869,282 bp from pter
End:
89,878,437 bp from pter
Size:
9,156 bases
Orientation:
Minus strand

Genomic View for TRIM64B Gene

Genes around TRIM64B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM64B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM64B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM64B Gene

No data available for Regulatory Elements for TRIM64B Gene

Proteins for TRIM64B Gene

  • Protein details for TRIM64B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NI03-TR64B_HUMAN
    Recommended name:
    Putative tripartite motif-containing protein 64B
    Protein Accession:
    A6NI03

    Protein attributes for TRIM64B Gene

    Size:
    449 amino acids
    Molecular mass:
    51557 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM64B Gene

Post-translational modifications for TRIM64B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM64B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM64B Gene

Domains & Families for TRIM64B Gene

Gene Families for TRIM64B Gene

Suggested Antigen Peptide Sequences for TRIM64B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NI03

UniProtKB/Swiss-Prot:

TR64B_HUMAN :
  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 1 B box-type zinc finger.
Domain:
  • Contains 1 B30.2/SPRY domain.
Family:
  • Belongs to the TRIM/RBCC family.
Similarity:
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM64B: view

Function for TRIM64B Gene

Gene Ontology (GO) - Molecular Function for TRIM64B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with TRIM64B: view

Phenotypes for TRIM64B Gene

GenomeRNAi human phenotypes for TRIM64B:
genes like me logo Genes that share phenotypes with TRIM64B: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIM64B Gene

Localization for TRIM64B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRIM64B Gene COMPARTMENTS Subcellular localization image for TRIM64B gene
Compartment Confidence
nucleus 3
cytosol 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for TRIM64B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM64B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRIM64B Gene

Pathways & Interactions for TRIM64B Gene

SuperPathways for TRIM64B Gene

No Data Available

Interacting Proteins for TRIM64B Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000332969%0d%0a9606.ENSP00000216297%0d%0a9606.ENSP00000278412%0d%0a9606.ENSP00000264108%0d%0a9606.ENSP00000262144%0d%0a9606.ENSP00000387982%0d%0a
Selected Interacting proteins: ENSP00000332969 A6NI03-TR64B_HUMAN for TRIM64B Gene via STRING IID

Gene Ontology (GO) - Biological Process for TRIM64B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRIM64B Gene

Transcripts for TRIM64B Gene

mRNA/cDNA for TRIM64B Gene

(3) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM64B Gene

No ASD Table

Relevant External Links for TRIM64B Gene

GeneLoc Exon Structure for
TRIM64B
ECgene alternative splicing isoforms for
TRIM64B

Expression for TRIM64B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRIM64B Gene

NURSA nuclear receptor signaling pathways regulating expression of TRIM64B Gene:

TRIM64B

SOURCE GeneReport for Unigene cluster for TRIM64B Gene:

Hs.730588
genes like me logo Genes that share expression patterns with TRIM64B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRIM64B Gene

Orthologs for TRIM64B Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM64B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRIM64B 34
  • 98.36 (n)
TRIM 35
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 35
  • 60 (a)
ManyToMany
-- 35
  • 58 (a)
ManyToMany
-- 35
  • 57 (a)
ManyToMany
-- 35
  • 57 (a)
ManyToMany
-- 35
  • 51 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 57 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 33 (a)
ManyToMany
-- 35
  • 32 (a)
ManyToMany
-- 35
  • 31 (a)
ManyToMany
-- 35
  • 31 (a)
ManyToMany
-- 35
  • 30 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 27 (a)
ManyToMany
-- 35
  • 27 (a)
ManyToMany
-- 35
  • 25 (a)
ManyToMany
-- 35
  • 20 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 18 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 30 (a)
ManyToMany
-- 35
  • 27 (a)
ManyToMany
-- 35
  • 25 (a)
ManyToMany
-- 35
  • 23 (a)
ManyToMany
-- 35
  • 22 (a)
ManyToMany
-- 35
  • 21 (a)
ManyToMany
-- 35
  • 18 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii trim109 35
  • 18 (a)
ManyToMany
Species where no ortholog for TRIM64B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM64B Gene

ENSEMBL:
Gene Tree for TRIM64B (if available)
TreeFam:
Gene Tree for TRIM64B (if available)

Paralogs for TRIM64B Gene

Pseudogenes.org Pseudogenes for TRIM64B Gene

genes like me logo Genes that share paralogs with TRIM64B: view

Variants for TRIM64B Gene

Sequence variations from dbSNP and Humsavar for TRIM64B Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10909600 -- 89,870,356(+) CATGA(A/C)TTTTA downstream-variant-500B, utr-variant-3-prime
rs10909601 -- 89,876,092(+) GGAAA(A/G)AAAGG intron-variant, upstream-variant-2KB
rs11018797 -- 89,876,846(+) AACCG(C/T)GATGC intron-variant, upstream-variant-2KB
rs111584426 -- 89,875,409(+) ACCTC(C/G)TTTAG intron-variant, upstream-variant-2KB
rs113477301 -- 89,873,232(+) ACAAA(C/T)TTTTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRIM64B Gene

Variant ID Type Subtype PubMed ID
dgv233n67 CNV gain 20364138
esv2759849 CNV gain+loss 17122850
esv3579817 CNV loss 25503493
esv3579830 CNV loss 25503493
esv3579831 CNV loss 25503493
esv3579993 CNV gain 25503493
esv3892056 CNV gain+loss 25118596
nsv1036092 CNV loss 25217958
nsv1043643 CNV gain 25217958
nsv1075433 CNV duplication 25765185
nsv1133000 OTHER inversion 24896259
nsv1139554 CNV duplication 24896259
nsv1152692 CNV duplication 26484159
nsv469862 CNV gain 16826518
nsv508645 CNV deletion 20534489
nsv7222 OTHER inversion 18451855
nsv832225 CNV gain 17160897
nsv8858 CNV gain+loss 18304495
nsv951053 CNV duplication 24416366
nsv972059 CNV duplication 23825009

Variation tolerance for TRIM64B Gene

Gene Damage Index Score: 3.56; 55.96% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRIM64B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRIM64B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM64B Gene

Disorders for TRIM64B Gene

Relevant External Links for TRIM64B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRIM64B

No disorders were found for TRIM64B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM64B Gene

Publications for TRIM64B Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 64
  2. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K. … Sawyer S.L. (PLoS Genet. 2011) 3 64

Products for TRIM64B Gene

Sources for TRIM64B Gene

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