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Aliases for TRIM64 Gene

Aliases for TRIM64 Gene

  • Tripartite Motif Containing 64 2 3
  • C11orf28 3 4
  • Tripartite Motif-Containing Protein 64 3
  • Chromosome 11 Open Reading Frame 28 2
  • Tripartite Motif-Containing 64 2
  • TRIM64A 3

External Ids for TRIM64 Gene

Previous HGNC Symbols for TRIM64 Gene

  • C11orf28

Previous GeneCards Identifiers for TRIM64 Gene

  • GC11P089336
  • GC11P089701
  • GC11M085791

Summaries for TRIM64 Gene

GeneCards Summary for TRIM64 Gene

TRIM64 (Tripartite Motif Containing 64) is a Protein Coding gene. An important paralog of this gene is TRIM64B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM64 Gene

Genomics for TRIM64 Gene

Regulatory Elements for TRIM64 Gene

Genomic Location for TRIM64 Gene

Start:
89,968,502 bp from pter
End:
89,975,228 bp from pter
Size:
6,727 bases
Orientation:
Plus strand

Genomic View for TRIM64 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIM64 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM64 Gene

Proteins for TRIM64 Gene

  • Protein details for TRIM64 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGJ6-TRI64_HUMAN
    Recommended name:
    Tripartite motif-containing protein 64
    Protein Accession:
    A6NGJ6
    Secondary Accessions:

    Protein attributes for TRIM64 Gene

    Size:
    449 amino acids
    Molecular mass:
    51566 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM64 Gene

Proteomics data for TRIM64 Gene at MOPED

Post-translational modifications for TRIM64 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM64 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM64 Gene

Domains for TRIM64 Gene

Gene Families for TRIM64 Gene

HGNC:
  • RNF :RING-type (C3HC4) zinc fingers
  • TRIM :Tripartite motif containing / Tripartite motif containing

Suggested Antigen Peptide Sequences for TRIM64 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NGJ6

UniProtKB/Swiss-Prot:

TRI64_HUMAN :
  • A6NGJ6
Domain:
  • Contains 1 B30.2/SPRY domain.
Family:
  • Belongs to the TRIM/RBCC family.
Similarity:
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM64: view

Function for TRIM64 Gene

Gene Ontology (GO) - Molecular Function for TRIM64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with TRIM64: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRIM64 Gene

Localization for TRIM64 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRIM64 Gene COMPARTMENTS Subcellular localization image for TRIM64 gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for TRIM64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM64: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRIM64 Gene

Pathways for TRIM64 Gene

SuperPathways for TRIM64 Gene

No Data Available

Interacting Proteins for TRIM64 Gene

Gene Ontology (GO) - Biological Process for TRIM64 Gene

None

No data available for Pathways by source for TRIM64 Gene

Transcripts for TRIM64 Gene

mRNA/cDNA for TRIM64 Gene

(0) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TRIM64 Gene

Tripartite motif containing 64:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM64 Gene

No ASD Table

Relevant External Links for TRIM64 Gene

GeneLoc Exon Structure for
TRIM64
ECgene alternative splicing isoforms for
TRIM64

Expression for TRIM64 Gene

mRNA expression in normal human tissues for TRIM64 Gene

SOURCE GeneReport for Unigene cluster for TRIM64 Gene Hs.454490

genes like me logo Genes that share expressions with TRIM64: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for TRIM64 Gene

Orthologs for TRIM64 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TRIM64 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRIM64B 35
  • 98.29 (n)
  • 96.64 (a)
Species with no ortholog for TRIM64:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRIM64 Gene

ENSEMBL:
Gene Tree for TRIM64 (if available)
TreeFam:
Gene Tree for TRIM64 (if available)

Paralogs for TRIM64 Gene

Paralogs for TRIM64 Gene

genes like me logo Genes that share paralogs with TRIM64: view

Variants for TRIM64 Gene

Sequence variations from dbSNP and Humsavar for TRIM64 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1818530 -- 89,971,260(-) GTAAA(A/C)TCACC intron-variant
rs2388214 -- 89,967,681(+) ATCAC(A/G)GTTGT upstream-variant-2KB
rs2388215 -- 89,967,702(+) tattc(A/G)taagt upstream-variant-2KB
rs2388216 -- 89,967,756(+) caggg(A/T)gaaaa upstream-variant-2KB
rs3070281 -- 89,967,797(+) ttttt(C/T)ttgag upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TRIM64 Gene

Variant ID Type Subtype PubMed ID
nsv898094 CNV Gain 21882294
dgv412e1 CNV Complex 17122850
dgv1257n71 CNV Loss 21882294
nsv832225 CNV Gain 17160897
nsv7222 OTHER Inversion 18451855
nsv469862 CNV Complex 16826518
essv22404 CNV CNV 17122850
nsv8858 CNV Gain+Loss 18304495
dgv1258n71 CNV Loss 21882294
dgv1261n71 CNV Loss 21882294
nsv898118 CNV Gain 21882294
dgv1265n71 CNV Loss 21882294
nsv898133 CNV Loss 21882294
nsv819015 CNV Loss 19587683
dgv1266n71 CNV Gain 21882294
nsv508646 CNV Loss 20534489
nsv898136 CNV Gain 21882294
nsv898137 CNV Gain+Loss 21882294
nsv898138 CNV Gain 21882294

Relevant External Links for TRIM64 Gene

HapMap Linkage Disequilibrium report
TRIM64

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM64 Gene

Disorders for TRIM64 Gene

No disorders were found for TRIM64 Gene.

No data available for UniProtKB/Swiss-Prot for TRIM64 Gene

Publications for TRIM64 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4
  2. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K. … Sawyer S.L. (PLoS Genet. 2011) 3

Products for TRIM64 Gene

  • Pathway & Disease-focused RT² Profiler PCR Arrays
    • Ubiquitin Ligases in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TRIM64
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM64
    • Block miRNA regulation of TRIM64 using miScript Target Protectors

    Sources for TRIM64 Gene

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