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TRIM58 Gene

protein-coding   GIFtS: 49
GCID: GC01P248020

Tripartite Motif Containing 58

(Previous name: tripartite motif-containing 58)
  Search for TRIM58
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tripartite Motif Containing 581 2
Tripartite Motif-Containing 581 2
BIA22
Tripartite Motif-Containing Protein 582
Protein BIA23

External Ids:    HGNC: 241501   Entrez Gene: 258932   Ensembl: ENSG000001627227   UniProtKB: Q8NG063   

Export aliases for TRIM58 gene to outside databases

Previous GC identifers: GC01P244347 GC01P246087 GC01P218409


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TRIM58 Gene:
TRIM58 (tripartite motif containing 58) is a protein-coding gene. An important paralog of this gene is TRIM7.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_167186.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRIM58 gene promoter:
         GR   E2F-4   E2F-3a   E2F-5   E2F-2   E47   GATA-2   E2F   E2F-1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM58 promoter sequence
   Search Chromatin IP Primers for TRIM58

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM58


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44   Ensembl cytogenetic band:  1q44   HGNC cytogenetic band: 1q44

TRIM58 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM58 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P248020:  view genomic region     (about GC identifiers)

Start:
248,020,501 bp from pter      End:
248,043,440 bp from pter
Size:
22,940 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TRI58_HUMAN, Q8NG06 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 58  
Size: 486 amino acids; 54766 Da
Sequence caution: Sequence=AAM63958.1; Type=Erroneous initiation;
Secondary accessions: Q6B0H9

Explore the universe of human proteins at neXtProt for TRIM58: NX_Q8NG06

Explore proteomics data for TRIM58 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRIM58 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056246.3  
    ENSEMBL proteins: 
     ENSP00000355437  

    TRIM58 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TRIM58

     
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    LSBio Antibodies in human, mouse, rat for TRIM58

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    Cloud-Clone Corp. CLIAs for TRIM58
    Search eBioscience for ELISAs for TRIM58 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    Selected InterPro protein domains (see all 10):
     IPR006574 PRY
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR001870 B30.2/SPRY
     IPR003877 SPRY_rcpt

    Graphical View of Domain Structure for InterPro Entry Q8NG06

    ProtoNet protein and cluster: Q8NG06

    1 Blocks protein domain: IPB003879 Butyrophylin C-terminal DUF signature

    UniProtKB/Swiss-Prot: TRI58_HUMAN, Q8NG06
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 RING-type zinc finger


    Find genes that share domains with TRIM58           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    Find genes that share ontologies with TRIM58           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TRIM58:
     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIM58
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TRIM58

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRIM58
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRIM58

    miRNA
    Products:
        
    miRTarBase miRNAs that target TRIM58:
    hsa-mir-26b-5p (MIRT029012)

    Block miRNA regulation of human, mouse, rat TRIM58 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TRIM58:
    hsa-miR-3658 hsa-miR-7-1* hsa-miR-7-2* hsa-miR-3065-5p hsa-miR-3914
    SwitchGear 3'UTR luciferase reporter plasmidTRIM58 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TRIM58
    Predesigned siRNA for gene silencing in human, mouse, rat TRIM58

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TRIM58

    Clone
    Products:
         
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    OriGene ORF clones in mouse, rat for TRIM58
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TRIM58 (NM_015431)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM58
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRIM58

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TRIM58 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM58


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--

    Find genes that share ontologies with TRIM58           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRIM58
    Interactions:

        Search GeneGlobe Interaction Network for TRIM58

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRIM58 (TRI58)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRIM58 gene: 
    NM_015431.3  

    Unigene Cluster for TRIM58:

    Tripartite motif containing 58
    Hs.269151  [show with all ESTs]
    Unigene Representative Sequence: NM_015431
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000366481(uc001ido.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TRIM58 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TRIM58:
    hsa-miR-3658 hsa-miR-7-1* hsa-miR-7-2* hsa-miR-3065-5p hsa-miR-3914
    SwitchGear 3'UTR luciferase reporter plasmidTRIM58 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TRIM58
    Predesigned siRNA for gene silencing in human, mouse, rat TRIM58
    Clone
    Products:
         
    OriGene clones in human, mouse for TRIM58 (see all 7)
    OriGene ORF clones in mouse, rat for TRIM58
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TRIM58 (NM_015431)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM58
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRIM58
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM58
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM58
      QuantiTect SYBR Green Assays in human, mouse, rat TRIM58
      QuantiFast Probe-based Assays in human, mouse, rat TRIM58

    Additional mRNA sequence: 

    AF327057.1 AK096188.1 BC074748.2 BC146848.1 BX537432.1 

    4 DOTS entries:

    DT.100741838  DT.409988  DT.432546  DT.95099806 

    Selected AceView cDNA sequences (see all 40):

    BC074748 BX644877 NM_015431 N54332 BX093298 BX509111 NM_001001957 W02471 
    CK002540 BX091434 AF327057 BV183401 CF993737 BX537432 AI217090 AK096188 
    BX110624 N75737 BQ025714 BU659945 N72691 AA346729 BG026581 AA719133 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRIM58 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TRIM58 Expression
    About this image


    TRIM58 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Blood (Hematopoietic System)
             Erythroblasts Hematopoietic Bone Marrow
     
     Liver (Hepatobiliary System)
    TRIM58 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRIM58 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.269151
        Custom PCR Arrays for TRIM58
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM58
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM58
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    QuantiFast Probe-based Assays in human, mouse, rat TRIM58
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM58

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TRIM58 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim581 , 5 tripartite motif-containing 581, 5 81.52(n)1
    79.92(a)1
      11 (36.23 cM)5
    2167811  NM_001039047.11  NP_001034136.11 
     586404655 
    chicken
    (Gallus gallus)
    Aves LOC7707181 tripartite motif-containing protein 39-like 58.64(n)
    46.17(a)
      770718  XM_001232969.3  XP_001232970.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    40(a)
    1 → many
    GL343252.1(1250717-1269864)


    ENSEMBL Gene Tree for TRIM58 (if available)
    TreeFam Gene Tree for TRIM58 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRIM58 gene
    TRIM72  TRIM42  TRIM392  TRIM342  TRIML12  TRIM272  TRIM682  TRIM602  
    TRIM222  TRIM172  TRIM52  TRIM62  TRIM6-TRIM342  TRIM212  TRIM382  TRIM112  
    TRIM39-RPP212  
    Selected SIMAP similar genes for TRIM58 using alignment to 1 protein entry:     TRI58_HUMAN(see all similar genes):
    TRIM21    TRIM68    BTNL9    TRIM39R    TRIM11    TRIM38
    DKFZp686F23130    TRIM39    TRIM5    TRIM17    TRIM6    BT3.3
    DKFZp781D1977    TRIM27    TRIM34    TRIM4    TRIML1    TRIM43

    Find genes that share paralogs with TRIM58           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRIM58 (see all 722)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs752116951,2
    F--248018584(+) GCTCTG/CCCTGT 1 -- us2k11Minor allele frequency- C:0.03NA 120
    rs1850652781,2
    --248018590(+) CCTGTC/TGCCAG 1 -- us2k10--------
    rs1440809861,2
    --248018639(+) ACAAAC/TCCCAG 1 -- us2k10--------
    rs777611451,2
    C,F--248018899(+) GCCCCC/GGACCC 1 -- us2k11Minor allele frequency- G:0.06WA 118
    rs1920957271,2
    --248018909(+) CTGCAA/GCCTCA 1 -- us2k10--------
    rs1823173991,2
    --248018960(+) ACCTTC/GCTTGC 1 -- us2k10--------
    rs1868813441,2
    --248018985(+) AATTAC/TATGTT 1 -- us2k10--------
    rs1917140981,2
    --248018989(+) ATATGC/TTTGCA 1 -- us2k10--------
    rs1827254341,2
    --248019052(+) GTCCCA/TCCTCT 1 -- us2k10--------
    rs1855329241,2
    --248019053(+) TCCCAC/TCTCTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TRIM58 (248020501 - 248043440 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TRIM58 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2727906CNV Deletion23290073
    esv1620378CNV Insertion17803354
    nsv5321CNV Loss18451855
    nsv873442CNV Gain21882294
    nsv873440CNV Gain21882294
    nsv827775CNV Gain20364138
    nsv873443CNV Gain21882294
    nsv819723CNV Gain19587683
    esv34503CNV Gain17911159
    nsv515858CNV Gain+Loss19592680

    Human Gene Mutation Database (HGMD): TRIM58
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM58
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM58

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TRIM58           About GenesLikeMe

    Genetic Association Database (GAD): TRIM58
    Human Genome Epidemiology (HuGE) Navigator: TRIM58 (1 document)

    Export disorders for TRIM58 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRIM58 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TRIM58)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association study of hematological and biochemical traits in a Japanese population. (PubMed id 20139978)1, 4 Kamatani Y....Kamatani N. (Nat. Genet. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Seventy-five genetic loci influencing the human red blood cell. (PubMed id 23222517)1 van der Harst P....Chambers J.C. (Nature 2012)
    4. New gene functions in megakaryopoiesis and platelet formation. (PubMed id 22139419)1 Gieger C....Soranzo N. (Nature 2011)
    5. Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. (PubMed id 21083371)4 Chinn L.W....O'Brien S.J. (J. Infect. Dis. 2010)
    6. Identification of host proteins required for HIV infection through a functional genomic screen. (PubMed id 18187620)1 Brass A.L....Elledge S.J. (Science 2008)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25893 HGNC: 24150 AceView: BIA2andOR2W3 Ensembl:ENSG00000162722 euGenes: HUgn25893
    ECgene: TRIM58 H-InvDB: TRIM58

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRIM58 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TRIM58 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRIM58 gene:
    Search GeneIP for patents involving TRIM58

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TRIM58  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TRIM58  
     OriGene MassSpec something-or-other for TRIM58   OriGene clones in human, mouse for TRIM58  
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     OriGene Custom Antibody Services for TRIM58   OriGene Custom Protein Services for TRIM58  

     
     
     Block miRNA regulation of human, mouse, rat TRIM58 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TRIM58
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM58 Predesigned siRNA for gene silencing in human, mouse, rat TRIM58
     QuantiFast Probe-based Assays in human, mouse, rat TRIM58 QuantiTect SYBR Green Assays in human, mouse, rat TRIM58
     Custom PCR Arrays for TRIM58 Search Chromatin IP Primers for TRIM58
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM58  Search GeneGlobe Interaction Network for TRIM58
     Regulatory tfbs in TRIM58 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TRIM58 GenScript cDNA clones with any tag delivered in your preferred vector for TRIM58
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     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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     Search Tocris compounds for TRIM58 (TRI58)
     Browse Sino Biological Proteins
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TRIM58 antibodies
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     See all of Abcam's Antibodies, Kits and Proteins for TRIM58
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     Browse ProSpec Recombinant Proteins
     Proteins for TRIM58
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     ELISAs for TRIM58
     CLIAs for TRIM58



     Browse ESI BIO Cell Lines and PureStem Progenitors for TRIM58
     Gene Synthesis
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     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM58
     SwitchGear 3'UTR luciferase reporter plasmids for TRIM58
     SwitchGear Promoter luciferase reporter plasmids for TRIM58
     Search ThermoFisher Antibodies for TRIM58
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRIM58
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIM58
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TRIM58
     LSBio Antibodies in human, mouse, rat for TRIM58
    Customized transgenic rodents for:
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     Browse compounds at ApexBio
     Search Addgene for plasmids for TRIM58
      Search eBioscience for proteins for TRIM58
      Search eBioscience for elisas for TRIM58
      eBioscience FlowRNA Probe Sets
           
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