Aliases for TRIM58 Gene
External Ids for TRIM58 Gene
Previous GeneCards Identifiers for TRIM58 Gene
GeneCards Summary for TRIM58 Gene
TRIM58 (Tripartite Motif Containing 58) is a Protein Coding gene. GO annotations related to this gene include ligase activity. An important paralog of this gene is TRIM21.
UniProtKB/Swiss-Prot for TRIM58 Gene
E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.