Aliases for TRIM56 Gene
External Ids for TRIM56 Gene
Previous GeneCards Identifiers for TRIM56 Gene
GeneCards Summary for TRIM56 Gene
TRIM56 (Tripartite Motif Containing 56) is a Protein Coding gene. Among its related pathways are Immune System and Cytosolic sensors of pathogen-associated DNA. GO annotations related to this gene include poly(A) RNA binding and ubiquitin-protein transferase activity. An important paralog of this gene is NHLRC4.
UniProtKB/Swiss-Prot for TRIM56 Gene
E3 ubiquitin-protein ligase that mediates Lys-63-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING Lys-63-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA (By similarity).