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TRIM55 Gene

protein-coding   GIFtS: 53
GCID: GC08P067039

Tripartite Motif Containing 55

(Previous names: ring finger protein 29, tripartite motif-containing 55)
(Previous symbol: RNF29)
Pneumococci & Pneumococcal Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tripartite Motif Containing 551 2     MURF-22
RNF291 2 3 5     muRF22
RING Finger Protein 291 2 3     Muscle Specific Ring Finger 22
Tripartite Motif-Containing 551 2     Tripartite Motif-Containing Protein 552
Muscle-Specific RING Finger Protein 22 3     MuRF-23
MURF23 5     MuRF23

External Ids:    HGNC: 142151   Entrez Gene: 846752   Ensembl: ENSG000001475737   OMIM: 6064695   UniProtKB: Q9BYV63   

Export aliases for TRIM55 gene to outside databases

Previous GC identifers: GC08P067202 GC08P062529


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRIM55 Gene:
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein
interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere
assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four
alternatively spliced transcript variants encoding distinct isoforms have been described. (provided by RefSeq,
Jul 2008)

GeneCards Summary for TRIM55 Gene:
TRIM55 (tripartite motif containing 55) is a protein-coding gene. Diseases associated with TRIM55 include hiv-1. GO annotations related to this gene include identical protein binding and signal transducer activity. An important paralog of this gene is TRIM13.

UniProtKB/Swiss-Prot: TRI55_HUMAN, Q9BYV6
Function: May regulate gene expression and protein turnover in muscle cells (By similarity)

Gene Wiki entry for TRIM55 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_008183.20  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRIM55 gene promoter:
         c-Fos   USF1   AML1a   FOXF2   AP-1   HTF   CUTL1   AREB6   Egr-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM55 promoter sequence
   Search Chromatin IP Primers for TRIM55

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM55


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q13.1   Ensembl cytogenetic band:  8q13.1   HGNC cytogenetic band: 8q13.1

TRIM55 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM55 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P067039:  view genomic region     (about GC identifiers)

Start:
67,039,131 bp from pter      End:
67,087,720 bp from pter
Size:
48,590 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TRI55_HUMAN, Q9BYV6 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 55  
Size: 548 amino acids; 60466 Da
Subunit: Homooligomer and heterooligomer (Probable). Interacts with titin/TTN. Interacts with myosins. Interacts
with SQSTM1 and NBR1. Isoform 4 may not able to interact with isoform 1, isoform 2 and isoform 3. Probably
interacts with TRIM63 and TRIM54
Caution: It is uncertain whether Met-1 or Met-17 is the initiator
Sequence caution: Sequence=AAP35876.1; Type=Erroneous initiation; Sequence=CAC32839.1; Type=Erroneous initiation;
Sequence=CAC32840.1; Type=Erroneous initiation;
Secondary accessions: B3KRC0 B3KRJ3 Q53XX3 Q8IUD9 Q8IUE4 Q96DV2 Q96DV3 Q9BYV5
Alternative splicing: 4 isoforms:  Q9BYV6-1   Q9BYV6-2   Q9BYV6-3   Q9BYV6-4   

Explore the universe of human proteins at neXtProt for TRIM55: NX_Q9BYV6

Explore proteomics data for TRIM55 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRIM55 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_149047.2  NP_908973.1  NP_908974.1  NP_908975.1  

    ENSEMBL proteins: 
     ENSP00000323913   ENSP00000297348   ENSP00000276573   ENSP00000332302  

    TRIM55 Human Recombinant Protein Products:

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    Novus Biologicals TRIM55 Protein
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    5 InterPro protein domains:
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR017903 COS_domain
     IPR000315 Znf_B-box
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q9BYV6

    ProtoNet protein and cluster: Q9BYV6

    2 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: TRI55_HUMAN, Q9BYV6
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 COS domain
    Similarity: Contains 1 RING-type zinc finger


    TRIM55 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRI55_HUMAN, Q9BYV6
    Function: May regulate gene expression and protein turnover in muscle cells (By similarity)

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity NAS11243782
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0042802identical protein binding IPI--
    GO:0046872metal ion binding ----
         
    TRIM55 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TRIM55:
     Decreased p24 protein expressi  Increased cell death HMECs cel 

         8 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Trim55):
     adipose tissue  cardiovascular system  growth/size/body  homeostasis/metabolism  liver/biliary system 
     mortality/aging  muscle  respiratory system 

    TRIM55 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Trim55tm1Slbt for TRIM55

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIM55
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    4 qRT-PCR Assays for microRNAs that regulate TRIM55:
    hsa-miR-9 hsa-miR-3673 hsa-miR-133a hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidTRIM55 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat TRIM55

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 4): TRIM55 (NM_184086)
    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TRI55_HUMAN, Q9BYV6: Cytoplasm (By similarity). Nucleus (By similarity). Note=Nuclear under atrophic conditions
    and upon mechanical signals. Localizes to the sarcomeric M-band in cardiomyocytes. Colocalizes in part with
    microtubules (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus3
    cytosol2
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0005874microtubule NAS11243782

    TRIM55 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRIM55
    Interactions:

        Search GeneGlobe Interaction Network for TRIM55

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    Selected Interacting proteins for TRIM55 (Q9BYV61, 2, 3 ENSP000003239134) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GFM1Q96RP92, 3, ENSP000004190384MINT-6492275 I2D: score=1 STRING: ENSP00000419038
    EEF1GP266412, 3MINT-6492286 I2D: score=1 
    CCAR1Q8IX122, 3, ENSP000002658724MINT-6492264 I2D: score=1 STRING: ENSP00000265872
    TRIM63Q969Q13, ENSP000003633904I2D: score=2 STRING: ENSP00000363390
    UBE2D2P628373, ENSP000003817174I2D: score=2 STRING: ENSP00000381717
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction NAS11243782

    TRIM55 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRIM55 (TRI55)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TRIM55 gene (4 alternative transcripts): 
    NM_033058.2  NM_184085.1  NM_184086.1  NM_184087.1  

    Unigene Cluster for TRIM55:

    Tripartite motif containing 55
    Hs.85524  [show with all ESTs]
    Unigene Representative Sequence: NM_033058
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000315962(uc003xvu.3 uc003xvv.3) ENST00000353317(uc003xvw.3 uc003xvx.3)
    ENST00000276573 ENST00000350034 ENST00000517647

    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate TRIM55:
    hsa-miR-9 hsa-miR-3673 hsa-miR-133a hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidTRIM55 3' UTR sequence
    Inhib. RNA
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM55
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM55
    Primer
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    OriGene qPCR primer pairs and template standards for TRIM55
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM55
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM55
      QuantiTect SYBR Green Assays in human, mouse, rat TRIM55
      QuantiFast Probe-based Assays in human, mouse, rat TRIM55

    Additional mRNA sequence: 

    AJ243488.1 AJ243489.1 AJ277493.1 AJ291712.1 AJ431704.1 AK091310.1 AK091728.1 BC007750.2 
    BT007212.1 

    7 DOTS entries:

    DT.40227561  DT.106551  DT.101982784  DT.95267856  DT.91703258  DT.100751677  DT.40292865 

    Selected AceView cDNA sequences (see all 69):

    BG674823 BC007750 BQ013623 NM_184087 AI655180 AJ572152 AA443309 AJ277493 
    AK091310 AI457692 NM_184085 BQ013358 AJ243489 NM_033058 AK091728 AA443443 
    NM_184086 AJ431704 AI634359 AX747148 AI917684 AJ291712 BX100765 BX116127 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRIM55 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTTTAAATA
    TRIM55 Expression
    About this image

    TRIM55 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRIM55 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.85524

    UniProtKB/Swiss-Prot: TRI55_HUMAN, Q9BYV6
    Tissue specificity: Highly expressed in muscle. Low-level expression in liver

        Custom PCR Arrays for TRIM55
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TRIM55 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim551 , 5 tripartite motif-containing 551, 5 85.33(n)1
    84.71(a)1
      3 (5.65 cM)5
    3814851  NM_001081281.11  NP_001074750.11 
     196444605 
    chicken
    (Gallus gallus)
    Aves TRIM551 tripartite motif containing 55 80.49(n)
    89.02(a)
      420166  NM_001199404.1  NP_001186333.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRIM556
    tripartite motif containing 55
    68(a)
    1 ↔ 1
    4(30683945-30725180)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.159182 Xenopus laevis transcribed sequence with moderate similarity more 79.29(n)    BJ033623.1 
    zebrafish
    (Danio rerio)
    Actinopterygii trim55b1 tripartite motif-containing 55b 70.31(n)
    71.7(a)
      664753  NM_001039982.1  NP_001035071.1 


    ENSEMBL Gene Tree for TRIM55 (if available)
    TreeFam Gene Tree for TRIM55 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRIM55 gene
    TRIM132  FSD1L2  TRIM462  TRIM632  TRIM592  TRIM92  TRIM672  TRIM362  
    MID12  MID22  TRIM542  FSD12  
    2 SIMAP similar genes for TRIM55 using alignment to 1 protein entry:     TRI55_HUMAN:
    TRIM54    TRIM63

    TRIM55 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRIM55 (see all 979)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs69982581,2
    C,F,H--67039389(+) CCACCG/AAGAGA 4 -- ut51 ese314Minor allele frequency- A:0.10NS EA NA WA 1890
    rs1155372501,2
    C,F--67039422(+) ACAATC/ACCTGG 4 -- ut511Minor allele frequency- A:0.04WA 118
    rs1496639861,2
    C--67039462(+) CACTCA/GCAGCA 4 -- ut510--------
    rs1919358641,2
    C--67039509(+) ATGAGC/TGCATC 8 S syn10--------
    rs1448692821,2
    C,F--67039512(+) AGCGCA/GTCTCT 8 A syn12Minor allele frequency- G:0.00NA EU 5873
    rs119915491,2
    C,F,H--67039605(+) TTCACG/AAAACC 8 /T syn1 ese322Minor allele frequency- A:0.04NS EA NA CSA WA 6784
    rs1833179031,2
    --67039784(+) TTGCCA/GGGCGC 4 -- int10--------
    rs1882703161,2
    --67039831(+) CTGAGA/GCCAGT 4 -- int10--------
    rs1458900561,2
    --67039839(+) AGTGGA/TTCACC 4 -- int10--------
    rs23576691,2
    C,F--67039939(+) gtggcG/Cggcac 4 -- int12Minor allele frequency- C:0.50WA 4

    HapMap Linkage Disequilibrium report for TRIM55 (67039131 - 67087720 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TRIM55:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2660962CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM55
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM55

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606469    OMIM disorders: --

    1 disease for TRIM55:    
    About MalaCards
    hiv-1


    TRIM55 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Genetic Association Database (GAD): TRIM55
    Human Genome Epidemiology (HuGE) Navigator: TRIM55 (2 documents)

    Export disorders for TRIM55 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRIM55 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with TRIM55)
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    1. Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain. (PubMed id 11243782)1, 2, 3 Centner T....Labeit S. (J. Mol. Biol. 2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The kinase domain of titin controls muscle gene expression and protein turnover. (PubMed id 15802564)1, 2 Lange S.... Gautel M. (Science 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein. (PubMed id 12414993)1, 2 Pizon V.... Gautel M. (J. Cell Sci. 2002)
    7. Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (amp 2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate. (PubMed id 22626734)1 Loch C.M. and Strickler J.E. (Biochim. Biophys. Acta 2012)
    10. Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy. (PubMed id 22666496)1 Shiffman D....Jukema J.W. (PLoS ONE 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84675 HGNC: 14215 AceView: RNF29 Ensembl:ENSG00000147573 euGenes: HUgn84675
    ECgene: TRIM55 H-InvDB: TRIM55

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRIM55 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TRIM55 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRIM55 gene:
    Search GeneIP for patents involving TRIM55

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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