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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRIM54 Gene

protein-coding   GIFtS: 48
GCID: GC02P027506

Tripartite Motif Containing 54

(Previous names: ring finger protein 30, tripartite motif-containing 54)
(Previous symbol: RNF30)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tripartite Motif Containing 541 2     Muscle-Specific RING-Finger Protein 32
RING Finger Protein 301 2 3     Tripartite Motif-Containing Protein 542
RNF301 2 3     MURF33
Tripartite Motif-Containing 541 2     MuRF3
Muscle-Specific RING Finger Protein 32 3     MuRF-33
MURF2 3     MuRF33
MURF-32     Muscle-Specific RING Finger Protein3
muRF32     

External Ids:    HGNC: 160081   Entrez Gene: 571592   Ensembl: ENSG000001381007   OMIM: 6064745   UniProtKB: Q9BYV23   

Export aliases for TRIM54 gene to outside databases

Previous GC identifers: GC02P027418 GC02P027247


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRIM54 Gene:
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins
RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers,
which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated
muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by
RefSeq, Jul 2008)

GeneCards Summary for TRIM54 Gene: 
TRIM54 (tripartite motif containing 54) is a protein-coding gene. Diseases associated with TRIM54 include cardiac rupture, and macular degeneration. GO annotations related to this gene include microtubule binding and signal transducer activity. An important paralog of this gene is TRIM13.

UniProtKB/Swiss-Prot: TRI54_HUMAN, Q9BYV2
Function: May bind and stabilize microtubules during myotubes formation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022184.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRIM54 gene promoter:
         GR   AML1a   Lmo2   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   CREB   E2F   E2F-1   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM54 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRIM54

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM54


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3   Ensembl cytogenetic band:  2p23.3   HGNC cytogenetic band: 2p23.3

TRIM54 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM54 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P027506:  view genomic region     (about GC identifiers)

Start:
27,505,260 bp from pter      End:
27,530,307 bp from pter
Size:
25,048 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TRI54_HUMAN, Q9BYV2 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 54  
Size: 358 amino acids; 40301 Da
Subunit: Homooligomer and heterooligomer. Interacts with tubulin (By similarity). Interacts with TRIM63 and
probably with TRIM55
Subcellular location: Cytoplasm, cytoskeleton (By similarity). Cytoplasm, myofibril, sarcomere, Z line (By
similarity). Note=Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity)
Sequence caution: Sequence=AAY24296.1; Type=Erroneous initiation; Sequence=CAC32841.1; Type=Erroneous initiation;
Sequence=CAC32842.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for TRIM54:
3Q1D (3D)    
Secondary accessions: A5D8T7 Q53SY4 Q9BYV3
Alternative splicing: 2 isoforms:  Q9BYV2-1   Q9BYV2-2   

Explore the universe of human proteins at neXtProt for TRIM54: NX_Q9BYV2

Explore proteomics data for TRIM54 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BYV2

  • TRIM54 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRIM54 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_115935.3  NP_912730.2  

    ENSEMBL proteins: 
     ENSP00000369415   ENSP00000296098  

    Human Recombinant Protein Products for TRIM54: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRIM54 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005874microtubule NAS11243782
    GO:0005875microtubule associated complex IEA--
    GO:0030018Z disc IEA--

    TRIM54 for ontologies           About GeneDecksing



    TRIM54 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for TRIM54


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    5 InterPro protein domains:
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR017903 COS_domain
     IPR000315 Znf_B-box
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q9BYV2

    ProtoNet protein and cluster: Q9BYV2

    2 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: TRI54_HUMAN, Q9BYV2
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 COS domain
    Similarity: Contains 1 RING-type zinc finger


    TRIM54 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRI54_HUMAN, Q9BYV2
    Function: May bind and stabilize microtubules during myotubes formation (By similarity)

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity NAS11243782
    GO:0005515protein binding ----
    GO:0008017microtubule binding IEA--
    GO:0008270zinc ion binding NAS11243782
    GO:0046872metal ion binding ----
         
    TRIM54 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TRIM54:
     Increased cell death in HCC-19 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Trim54):
     behavior/neurological  cardiovascular system  cellular  mortality/aging  muscle 

    TRIM54 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Trim54tm1Eno for TRIM54

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRIM54 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TRIM54

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    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM54:
    hsa-miR-548t hsa-miR-593
    SwitchGear 3'UTR luciferase reporter plasmidTRIM54 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM54


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIM54

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/9 Interacting proteins for TRIM54 (Q9BYV23 ENSP000002960984) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIM63Q969Q13, ENSP000003633904I2D: score=2 STRING: ENSP00000363390
    UBE2UQ5VVX93, ENSP000003601164I2D: score=2 STRING: ENSP00000360116
    CKMP067323, ENSP000002214764I2D: score=1 STRING: ENSP00000221476
    UBE2IP632793, ENSP000003248974I2D: score=1 STRING: ENSP00000324897
    TRIM55Q9BYV63, ENSP000003239134I2D: score=1 STRING: ENSP00000323913
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007017microtubule-based process NAS11243782
    GO:0007026negative regulation of microtubule depolymerization NAS11243782
    GO:0007165signal transduction NAS11243782
    GO:0007275multicellular organismal development IEA--
    GO:0030154cell differentiation IEA--

    TRIM54 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRIM54 (TRI54)

    Search CenterWatch for drugs/clinical trials and news about TRIM54 / TRI54

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRIM54 gene (2 alternative transcripts): 
    NM_032546.3  NM_187841.2  

    Unigene Cluster for TRIM54:

    Tripartite motif containing 54
    Hs.516036  [show with all ESTs]
    Unigene Representative Sequence: NM_032546
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380075(uc002rjo.3) ENST00000296098(uc002rjn.3) ENST00000488321
    ENST00000485306
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM54
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM54:
    hsa-miR-548t hsa-miR-593
    SwitchGear 3'UTR luciferase reporter plasmidTRIM54 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AJ291714.1 AK300699.1 BC141807.1 

    5 DOTS entries:

    DT.97810288  DT.91755592  DT.91717945  DT.100739790  DT.75102302 

    24/40 AceView cDNA sequences (see all 40):

    BF058468 NM_032546 AI971801 CA417215 AI352333 F26252 AI631150 NM_187841 
    BM726338 AJ291714 BM680943 BU633919 AA182748 BF941825 AJ403135 AA868267 
    AA625641 AA447961 CA423690 AA428229 F23238 CA423735 AW294748 AA808889 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRIM54 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACCTGGCTG
    TRIM54 Expression
    About this image


    See TRIM54 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRIM54

    SOURCE GeneReport for Unigene cluster: Hs.516036

    UniProtKB/Swiss-Prot: TRI54_HUMAN, Q9BYV2
    Tissue specificity: Specifically expressed in heart and skeletal muscle

        SABiosciences Expression via Pathway-Focused PCR Array including TRIM54: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TRIM54 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim541 , 5 tripartite motif-containing 541, 5 89.66(n)1
    95.53(a)1
      5 (17.06 cM)5
    585221  NM_021447.21  NP_067422.11 
     311167125 
    zebrafish
    (Danio rerio)
    Actinopterygii trim541 tripartite motif-containing 54 71.56(n)
    75.17(a)
      563772  NM_001045025.1  NP_001038490.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Trim96
    Trim9
    11(a)
    1 → many
    2L(10544881-10627374)
    worm
    (Caenorhabditis elegans)
    Secernentea trim-96
    Protein TRIM-9, isoform b
    10(a)
    1 → many
    V(1223897-1235445)


    ENSEMBL Gene Tree for TRIM54 (if available)
    TreeFam Gene Tree for TRIM54 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRIM54 gene
    TRIM132  ENSG000002487102  FSD1L2  TRIM462  TRIM632  TRIM592  TRIM92  TRIM672  
    TRIM362  TRIM552  MID12  MID22  FSD12  
    2 SIMAP similar genes for TRIM54 using alignment to 1 protein entry:     TRI54_HUMAN:
    TRIM55    TRIM63

    TRIM54 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/498 SNPs in TRIM54 are shown (see all 498)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1165584641,2
    C,F--27505023(+) AAGAAG/AGGCCC 2 -- us2k11Minor allele frequency- A:0.06WA 118
    rs1851094501,2
    --27505386(+) ACTACA/GTGAGC 2 -- ut510--------
    rs1484948811,2
    C--27505401(+) CGAGGA/GTGCAG 2 -- ut510--------
    rs1901415031,2
    --27505435(+) AGACTG/TCTATC 2 -- ut510--------
    rs773269531,2
    C,F--27505446(+) TGGGAC/AGAGAC 2 -- ut511Minor allele frequency- A:0.05WA 118
    rs1811828611,2
    --27505525(+) GCCATC/GTAAGC 2 -- ut510--------
    rs1855781491,2
    C--27505583(+) GCCAGA/GCACGA 2 -- ut510--------
    rs1426721681,2
    C,F--27505680(+) TGCCCC/TATCTG 4 P syn11Minor allele frequency- T:0.01NA 4552
    rs1509932711,2
    C--27505741(+) TGTGCC/TGCAAA 4 R C mis10--------
    rs339949281,2
    C,F--27505758(+) AACGAC/TGTCTT 4 D syn14Minor allele frequency- T:0.05NA EU 5874

    HapMap Linkage Disequilibrium report for TRIM54 (27505260 - 27530307 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TRIM54:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2719835CNV Deletion23290073
    esv2571212CNV Insertion19546169
    nsv873754CNV Loss21882294
    nsv833614CNV Gain17160897
    esv33516CNV Gain17666407

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606474    OMIM disorders: --

    4 diseases for TRIM54:    About MalaCards
    cardiac rupture    macular degeneration    ataxia    myocardial infarction


    TRIM54 for disorders           About GeneDecksing


    Export disorders for TRIM54 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRIM54 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with TRIM54)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain. (PubMed id 11243782)1, 2, 3 Centner T....Labeit S. (2001)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    3. A microarray of ubiquitylated proteins for profiling d eubiquitylase activity reveals the critical roles of both chain and substrate. (PubMed id 22626734)1 Loch C.M. and Strickler J.E. (2012)
    4. Comparison of an expanded ataxia interactome with pat ient medical records reveals a relationship between macular degeneration and at axia. (PubMed id 21078624)1 Kahle J.J....Zoghbi H.Y. (2011)
    5. The Ubiquitin-interacting Motif Protein, S5a, Is Ubiquitinated by All Types of Ubiquitin Ligases by a Mechanism Different from Typical Substrate Recognition. (PubMed id 19240029)1 Uchiki T....Goldberg A.L. (2009)
    6. A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PubMed id 19690564)1 van Wijk S.J....Timmers H.T. (2009)
    7. Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction. (PubMed id 17360532)1 Fielitz J....Olson E.N. (2007)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1. (PubMed id 11927605)1 McElhinny A.S.... Gregorio C.C. (2002)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57159 HGNC: 16008 AceView: RNF30 Ensembl:ENSG00000138100 euGenes: HUgn57159
    ECgene: TRIM54 H-InvDB: TRIM54

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for TRIM54 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRIM54 gene:
    Search GeneIP for patents involving TRIM54

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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