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Aliases for TRIM49D1 Gene

Aliases for TRIM49D1 Gene

  • Tripartite Motif Containing 49D1 2 3
  • Tripartite Motif-Containing Protein 49-Like Protein 3 4
  • Tripartite Motif-Containing Protein 49D2 Pseudogene 3 4
  • Tripartite Motif Containing 49D1, Pseudogene 2 3
  • Tripartite Motif Containing 49D, Pseudogene 2 3
  • Tripartite Motif-Containing Protein 49D1 3
  • Tripartite Motif Containing 49D 2
  • TRIM49D1 TRIM49D2P 4
  • TRIM49D2P 3
  • TRIM49D1P 3
  • TRIM49DP 3
  • TRIM49L1 4
  • TRIM49D 3
  • TRIM49L 4

External Ids for TRIM49D1 Gene

Previous HGNC Symbols for TRIM49D1 Gene

  • TRIM49DP
  • TRIM49D1P

Previous GeneCards Identifiers for TRIM49D1 Gene

  • GC11M089649

Summaries for TRIM49D1 Gene

GeneCards Summary for TRIM49D1 Gene

TRIM49D1 (Tripartite Motif Containing 49D1) is a Protein Coding gene. An important paralog of this gene is TRIM77.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM49D1 Gene

Genomics for TRIM49D1 Gene

Genomic Location for TRIM49D1 Gene

Start:
89,911,111 bp from pter
End:
89,921,767 bp from pter
Size:
10,657 bases
Orientation:
Minus strand

Genomic View for TRIM49D1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIM49D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM49D1 Gene

No data available for Regulatory Elements for TRIM49D1 Gene

Proteins for TRIM49D1 Gene

  • Protein details for TRIM49D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9J1S8-T49D1_HUMAN
    Recommended name:
    Tripartite motif-containing protein 49D1
    Protein Accession:
    C9J1S8
    Secondary Accessions:
    • I1YAP9

    Protein attributes for TRIM49D1 Gene

    Size:
    452 amino acids
    Molecular mass:
    52496 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM49D1 Gene

Proteomics data for TRIM49D1 Gene at MOPED

Post-translational modifications for TRIM49D1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM49D1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM49D1 Gene

Domains for TRIM49D1 Gene

Gene Families for TRIM49D1 Gene

HGNC:
  • RNF :RING-type (C3HC4) zinc fingers
  • TRIM :Tripartite motif containing / Tripartite motif containing

Protein Domains for TRIM49D1 Gene

Graphical View of Domain Structure for InterPro Entry

C9J1S8

UniProtKB/Swiss-Prot:

T49D1_HUMAN :
  • C9J1S8
Domain:
  • Contains 1 B30.2/SPRY domain.
Family:
  • Belongs to the TRIM/RBCC family.
Similarity:
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM49D1: view

No data available for Suggested Antigen Peptide Sequences for TRIM49D1 Gene

Function for TRIM49D1 Gene

Gene Ontology (GO) - Molecular Function for TRIM49D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with TRIM49D1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRIM49D1 Gene

Localization for TRIM49D1 Gene

Gene Ontology (GO) - Cellular Components for TRIM49D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM49D1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TRIM49D1 Gene

Pathways for TRIM49D1 Gene

SuperPathways for TRIM49D1 Gene

No Data Available

Interacting Proteins for TRIM49D1 Gene

Gene Ontology (GO) - Biological Process for TRIM49D1 Gene

None

No data available for Pathways by source for TRIM49D1 Gene

Transcripts for TRIM49D1 Gene

mRNA/cDNA for TRIM49D1 Gene

(2) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM49D1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM49D1 Gene

No ASD Table

Relevant External Links for TRIM49D1 Gene

GeneLoc Exon Structure for
TRIM49D1
ECgene alternative splicing isoforms for
TRIM49D1

Expression for TRIM49D1 Gene

mRNA expression in normal human tissues for TRIM49D1 Gene

Protein differential expression in normal tissues for TRIM49D1 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TRIM49D1 Gene

SOURCE GeneReport for Unigene cluster for TRIM49D1 Gene Hs.705301

genes like me logo Genes that share expressions with TRIM49D1: view

Expression partners for TRIM49D1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TRIM49D1 Gene

Orthologs for TRIM49D1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM49D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRIM49 35
  • 98.85 (n)
  • 97.53 (a)
-- 36
  • 72 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 32 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 21 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 26 (a)
ManyToMany
-- 36
  • 25 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 17 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 28 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 19 (a)
ManyToMany
-- 36
  • 22 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii trim108 36
  • 18 (a)
ManyToMany
Species with no ortholog for TRIM49D1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM49D1 Gene

ENSEMBL:
Gene Tree for TRIM49D1 (if available)
TreeFam:
Gene Tree for TRIM49D1 (if available)

Paralogs for TRIM49D1 Gene

Selected SIMAP similar genes for TRIM49D1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TRIM49D1: view

Variants for TRIM49D1 Gene

Sequence variations from dbSNP and Humsavar for TRIM49D1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs58118513 -- 89,919,564(+) TGGAG(A/G)GCCCT upstream-variant-2KB
rs60214420 -- 89,919,652(+) TTTTA(G/T)TGAAA upstream-variant-2KB
rs60793278 -- 89,912,121(+) AAATA(-/AATAAATAAATA)GAAAG intron-variant
rs61906473 -- 89,917,856(+) CAAAA(A/T)TAAAA upstream-variant-2KB
rs112973335 -- 89,918,651(+) ATGTG(A/G)GTGGG upstream-variant-2KB

Relevant External Links for TRIM49D1 Gene

HapMap Linkage Disequilibrium report
TRIM49D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TRIM49D1 Gene

Disorders for TRIM49D1 Gene

No disorders were found for TRIM49D1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TRIM49D1 Gene

Publications for TRIM49D1 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4
  2. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K. … Sawyer S.L. (PLoS Genet. 2011) 3 4

Products for TRIM49D1 Gene

Sources for TRIM49D1 Gene

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