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Aliases for TRIM49D1 Gene

Aliases for TRIM49D1 Gene

  • Tripartite Motif Containing 49D1 2 3 5
  • Tripartite Motif-Containing Protein 49-Like Protein 3 4
  • Tripartite Motif Containing 49D1, Pseudogene 2 3
  • Tripartite Motif Containing 49D, Pseudogene 2 3
  • Tripartite Motif-Containing Protein 49D1 3 4
  • TRIM49D2P 3 4
  • Tripartite Motif-Containing Protein 49D2 Pseudogene 3
  • Tripartite Motif-Containing Protein 49D2 4
  • Tripartite Motif Containing 49D 2
  • TRIM49D1 TRIM49D2 4
  • TRIM49D1P 3
  • TRIM49D2 3
  • TRIM49DP 3
  • TRIM49L1 4
  • TRIM49D 3
  • TRIM49L 4

External Ids for TRIM49D1 Gene

Previous HGNC Symbols for TRIM49D1 Gene

  • TRIM49DP
  • TRIM49D1P

Previous GeneCards Identifiers for TRIM49D1 Gene

  • GC11M089649

Summaries for TRIM49D1 Gene

GeneCards Summary for TRIM49D1 Gene

TRIM49D1 (Tripartite Motif Containing 49D1) is a Protein Coding gene. An important paralog of this gene is TRIM64C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM49D1 Gene

Genomics for TRIM49D1 Gene

Genomic Location for TRIM49D1 Gene

Chromosome:
11
Start:
89,911,111 bp from pter
End:
89,921,767 bp from pter
Size:
10,657 bases
Orientation:
Minus strand

Genomic View for TRIM49D1 Gene

Genes around TRIM49D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM49D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM49D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM49D1 Gene

No data available for Regulatory Elements for TRIM49D1 Gene

Proteins for TRIM49D1 Gene

  • Protein details for TRIM49D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9J1S8-TR49D_HUMAN
    Recommended name:
    Tripartite motif-containing protein 49D
    Protein Accession:
    C9J1S8
    Secondary Accessions:
    • I1YAP9

    Protein attributes for TRIM49D1 Gene

    Size:
    452 amino acids
    Molecular mass:
    52496 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM49D1 Gene

Proteomics data for TRIM49D1 Gene at MOPED

Post-translational modifications for TRIM49D1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM49D1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM49D1 Gene

Domains & Families for TRIM49D1 Gene

Gene Families for TRIM49D1 Gene

Protein Domains for TRIM49D1 Gene

Graphical View of Domain Structure for InterPro Entry

C9J1S8

UniProtKB/Swiss-Prot:

TR49D_HUMAN :
  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 1 B box-type zinc finger.
Domain:
  • Contains 1 B30.2/SPRY domain.
Family:
  • Belongs to the TRIM/RBCC family.
Similarity:
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM49D1: view

No data available for Suggested Antigen Peptide Sequences for TRIM49D1 Gene

Function for TRIM49D1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIM49D1 Gene

Localization for TRIM49D1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRIM49D1 Gene

Pathways & Interactions for TRIM49D1 Gene

SuperPathways for TRIM49D1 Gene

No Data Available

Interacting Proteins for TRIM49D1 Gene

Gene Ontology (GO) - Biological Process for TRIM49D1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRIM49D1 Gene

Drugs & Compounds for TRIM49D1 Gene

No Compound Related Data Available

Transcripts for TRIM49D1 Gene

mRNA/cDNA for TRIM49D1 Gene

(2) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM49D1 Gene

No ASD Table

Relevant External Links for TRIM49D1 Gene

GeneLoc Exon Structure for
TRIM49D1
ECgene alternative splicing isoforms for
TRIM49D1

Expression for TRIM49D1 Gene

mRNA expression in normal human tissues for TRIM49D1 Gene

Protein differential expression in normal tissues from HIPED for TRIM49D1 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TRIM49D1 Gene



SOURCE GeneReport for Unigene cluster for TRIM49D1 Gene Hs.705301

genes like me logo Genes that share expression patterns with TRIM49D1: view

Protein tissue co-expression partners for TRIM49D1 Gene

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TRIM49D1 Gene

Orthologs for TRIM49D1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM49D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRIM49 35
  • 98.85 (n)
  • 97.53 (a)
-- 36
  • 72 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 32 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 21 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 26 (a)
ManyToMany
-- 36
  • 25 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 17 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 28 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 19 (a)
ManyToMany
-- 36
  • 22 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii trim108 36
  • 18 (a)
ManyToMany
Species with no ortholog for TRIM49D1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM49D1 Gene

ENSEMBL:
Gene Tree for TRIM49D1 (if available)
TreeFam:
Gene Tree for TRIM49D1 (if available)

Paralogs for TRIM49D1 Gene

(16) SIMAP similar genes for TRIM49D1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TRIM49D1: view

Variants for TRIM49D1 Gene

Sequence variations from dbSNP and Humsavar for TRIM49D1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1849822 -- 89,919,184(-) CGTGG(C/T)GGGCA intron-variant, upstream-variant-2KB
rs1949287 -- 89,921,545(-) GAACC(G/T)TGACA upstream-variant-2KB
rs2076861 -- 89,921,729(+) TCAAA(A/G)CTTTG upstream-variant-2KB
rs7129963 -- 89,921,567(+) CAGAT(C/T)CCATA upstream-variant-2KB
rs61906473 -- 89,917,856(+) CAAAA(A/T)TAAAA intron-variant, upstream-variant-2KB

Variation tolerance for TRIM49D1 Gene

Gene Damage Index Score: 0.37; 8.24% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for TRIM49D1 Gene

Disorders for TRIM49D1 Gene

Relevant External Links for TRIM49D1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRIM49D1

No disorders were found for TRIM49D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM49D1 Gene

Publications for TRIM49D1 Gene

  1. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K. … Sawyer S.L. (PLoS Genet. 2011) 3 4 67
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3

Products for TRIM49D1 Gene

Sources for TRIM49D1 Gene

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